#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75342 uniprotkb:Q9BYJ1 intact:EBI-6925925|ensembl:ENSP00000497784 intact:EBI-6925949|ensembl:ENSP00000314879|ensembl:ENSP00000369494|ensembl:ENSP00000400581|uniprotkb:B2R981|uniprotkb:B7Z3W0|uniprotkb:Q3ZB74|uniprotkb:Q9H4F2|uniprotkb:Q9HC22 psi-mi:lx12b_human(display_long)|uniprotkb:ALOX12B(gene name)|psi-mi:ALOX12B(display_short)|uniprotkb:Epidermis-type lipoxygenase 12(gene name synonym) psi-mi:loxe3_human(display_long)|uniprotkb:Hydroperoxy icosatetraenoate dehydratase(gene name synonym)|uniprotkb:ALOXE3(gene name)|psi-mi:ALOXE3(display_short)|uniprotkb:Epidermis-type lipoxygenase 3(gene name synonym)|uniprotkb:Hydroperoxy dehydratase ALOXE3(gene name synonym)|uniprotkb:Hydroperoxy icosatetraenoate isomerase(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Li et al. (2012) pubmed:22622417|imex:IM-21147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-6925923|imex:IM-21147-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000179477(gene)|ensembl:ENST00000647874(transcript)|go:"GO:0004052"("arachidonate 12(S)-lipoxygenase activity")|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0016829"(lyase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0034440"(lipid oxidation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047677"("arachidonate 8(R)-lipoxygenase activity")|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0106237"("arachidonate 12(R)-lipoxygenase activity")|go:"GO:1990136"(linoleate 9S-lipoxygenase activity)|interpro:IPR000907(Lipoxygenase)|go:"GO:0051122"(hepoxilin biosynthetic process)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|reactome:R-HSA-2142712|refseq:NP_001130.1 ensembl:ENSG00000179148(gene)|ensembl:ENST00000318227(transcript)|ensembl:ENST00000380149(transcript)|ensembl:ENST00000448843(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050486"(intramolecular transferase activity, transferring hydroxy groups)|go:"GO:0051120"(hepoxilin A3 synthase activity)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0106255"(hydroperoxy icosatetraenoate isomerase activity)|go:"GO:0106256"(hydroperoxy icosatetraenoate dehydratase activity)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|rcsb pdb:6VB2|reactome:R-HSA-2142712|refseq:NP_001159432.1|refseq:NP_067641.2 - - - figure legend:4a-f, S5a-f, 6e, S10e|comment:"Interaction is increased in patients with NIPAL4 mutations (homozygous for the missense mutation p.Ala176Asp)."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-skin)|taxid:9606(Homo sapiens skin) - 2013/08/12 2014/10/16 rogid:TSuCh5lL8Vv86lLm4iOqyYBXGRw9606 rogid:X+cUOat5/4dAu1URlD51JvVR9yU9606 intact-crc:ED4861A9F845EF87|rigid:7qguBbWHkWOSAiWXMfuWoFYj6Hk false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P22735 uniprotkb:Q9BYJ1 intact:EBI-2562368|uniprotkb:Q197M4|ensembl:ENSP00000206765|ensembl:ENSP00000493587|uniprotkb:B4DWR7 intact:EBI-6925949|ensembl:ENSP00000314879|ensembl:ENSP00000369494|ensembl:ENSP00000400581|uniprotkb:B2R981|uniprotkb:B7Z3W0|uniprotkb:Q3ZB74|uniprotkb:Q9H4F2|uniprotkb:Q9HC22 psi-mi:tgm1_human(display_long)|uniprotkb:KTG(gene name synonym)|uniprotkb:Transglutaminase K(gene name synonym)|uniprotkb:Transglutaminase-1(gene name synonym)|uniprotkb:Epidermal TGase(gene name synonym)|uniprotkb:TGM1(gene name)|psi-mi:TGM1(display_short) psi-mi:loxe3_human(display_long)|uniprotkb:Hydroperoxy icosatetraenoate dehydratase(gene name synonym)|uniprotkb:ALOXE3(gene name)|psi-mi:ALOXE3(display_short)|uniprotkb:Epidermis-type lipoxygenase 3(gene name synonym)|uniprotkb:Hydroperoxy dehydratase ALOXE3(gene name synonym)|uniprotkb:Hydroperoxy icosatetraenoate isomerase(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Li et al. (2012) pubmed:22622417|imex:IM-21147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-6926034|imex:IM-21147-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000350.1|ensembl:ENSG00000092295(gene)|ensembl:ENSG00000285348(gene)|ensembl:ENST00000206765(transcript)|ensembl:ENST00000642845(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031424"(keratinization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043163"(cell envelope organization)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|rcsb pdb:2XZZ|reactome:R-HSA-6809371 ensembl:ENSG00000179148(gene)|ensembl:ENST00000318227(transcript)|ensembl:ENST00000380149(transcript)|ensembl:ENST00000448843(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050486"(intramolecular transferase activity, transferring hydroxy groups)|go:"GO:0051120"(hepoxilin A3 synthase activity)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0106255"(hydroperoxy icosatetraenoate isomerase activity)|go:"GO:0106256"(hydroperoxy icosatetraenoate dehydratase activity)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|rcsb pdb:6VB2|reactome:R-HSA-2142712|refseq:NP_001159432.1|refseq:NP_067641.2 - - - figure legend:5a-f, S7a-f, S8|comment:"Interaction is increased in patients with ALOX12B (homozygous for the missense mutation(s) p.Gly462Asp or compound heterozygous for p.Pro422Leu and p.Tyr521Cys) and ALOXE3 (compound heterozygous for the missense mutations p.Arg234X and p.Pro630Leu or compound heterozygous for the donor splice site mutations c.1305+1G>T and c.1305+2A>T) mutations."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-skin)|taxid:9606(Homo sapiens skin) - 2013/08/12 2014/10/16 rogid:5kr1FHRSfYLveMKchu772fNbkDM9606 rogid:X+cUOat5/4dAu1URlD51JvVR9yU9606 intact-crc:A9B4369891B72184|rigid:IuPChBVPiaFuCKkal/YRZre2jjY false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P22735 uniprotkb:O75342 intact:EBI-2562368|uniprotkb:Q197M4|ensembl:ENSP00000206765|ensembl:ENSP00000493587|uniprotkb:B4DWR7 intact:EBI-6925925|ensembl:ENSP00000497784 psi-mi:tgm1_human(display_long)|uniprotkb:KTG(gene name synonym)|uniprotkb:Transglutaminase K(gene name synonym)|uniprotkb:Transglutaminase-1(gene name synonym)|uniprotkb:Epidermal TGase(gene name synonym)|uniprotkb:TGM1(gene name)|psi-mi:TGM1(display_short) psi-mi:lx12b_human(display_long)|uniprotkb:ALOX12B(gene name)|psi-mi:ALOX12B(display_short)|uniprotkb:Epidermis-type lipoxygenase 12(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Li et al. (2012) pubmed:22622417|imex:IM-21147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-6926188|imex:IM-21147-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000350.1|ensembl:ENSG00000092295(gene)|ensembl:ENSG00000285348(gene)|ensembl:ENST00000206765(transcript)|ensembl:ENST00000642845(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031424"(keratinization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043163"(cell envelope organization)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|rcsb pdb:2XZZ|reactome:R-HSA-6809371 ensembl:ENSG00000179477(gene)|ensembl:ENST00000647874(transcript)|go:"GO:0004052"("arachidonate 12(S)-lipoxygenase activity")|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0016829"(lyase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0034440"(lipid oxidation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047677"("arachidonate 8(R)-lipoxygenase activity")|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0106237"("arachidonate 12(R)-lipoxygenase activity")|go:"GO:1990136"(linoleate 9S-lipoxygenase activity)|interpro:IPR000907(Lipoxygenase)|go:"GO:0051122"(hepoxilin biosynthetic process)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|reactome:R-HSA-2142712|refseq:NP_001130.1 - - - figure legend:S9a-f|comment:"Interaction is increased in patients with ALOX12B mutations (homozygous for the missense mutation(s) p.Gly462Asp or compound heterozygous for p.Pro422Leu and p.Tyr521Cys)."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-skin)|taxid:9606(Homo sapiens skin) - 2013/08/12 2014/10/16 rogid:5kr1FHRSfYLveMKchu772fNbkDM9606 rogid:TSuCh5lL8Vv86lLm4iOqyYBXGRw9606 intact-crc:E58A6D117D74694E|rigid:OxjoJnpqGDI+MBSlXDGHoWFQAoE false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9BYJ1 uniprotkb:O75342 intact:EBI-6925949|ensembl:ENSP00000314879|ensembl:ENSP00000369494|ensembl:ENSP00000400581|uniprotkb:B2R981|uniprotkb:B7Z3W0|uniprotkb:Q3ZB74|uniprotkb:Q9H4F2|uniprotkb:Q9HC22 intact:EBI-6925925|ensembl:ENSP00000497784 psi-mi:loxe3_human(display_long)|uniprotkb:Hydroperoxy icosatetraenoate dehydratase(gene name synonym)|uniprotkb:ALOXE3(gene name)|psi-mi:ALOXE3(display_short)|uniprotkb:Epidermis-type lipoxygenase 3(gene name synonym)|uniprotkb:Hydroperoxy dehydratase ALOXE3(gene name synonym)|uniprotkb:Hydroperoxy icosatetraenoate isomerase(gene name synonym) psi-mi:lx12b_human(display_long)|uniprotkb:ALOX12B(gene name)|psi-mi:ALOX12B(display_short)|uniprotkb:Epidermis-type lipoxygenase 12(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2012) pubmed:22622417|imex:IM-21147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6926012|imex:IM-21147-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000179148(gene)|ensembl:ENST00000318227(transcript)|ensembl:ENST00000380149(transcript)|ensembl:ENST00000448843(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050486"(intramolecular transferase activity, transferring hydroxy groups)|go:"GO:0051120"(hepoxilin A3 synthase activity)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0106255"(hydroperoxy icosatetraenoate isomerase activity)|go:"GO:0106256"(hydroperoxy icosatetraenoate dehydratase activity)|interpro:IPR000907(Lipoxygenase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|rcsb pdb:6VB2|reactome:R-HSA-2142712|refseq:NP_001159432.1|refseq:NP_067641.2 ensembl:ENSG00000179477(gene)|ensembl:ENST00000647874(transcript)|go:"GO:0004052"("arachidonate 12(S)-lipoxygenase activity")|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0016829"(lyase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0034440"(lipid oxidation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047677"("arachidonate 8(R)-lipoxygenase activity")|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0106237"("arachidonate 12(R)-lipoxygenase activity")|go:"GO:1990136"(linoleate 9S-lipoxygenase activity)|interpro:IPR000907(Lipoxygenase)|go:"GO:0051122"(hepoxilin biosynthetic process)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001885(Lipoxygenase, mammalian)|interpro:IPR013819(Lipoxygenase, C-terminal)|interpro:IPR020833|interpro:IPR020834|interpro:IPR036226|interpro:IPR036392|interpro:IPR042062|reactome:R-HSA-2142712|refseq:NP_001130.1 - - - figure legend:S6a, S6b|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-skin)|taxid:9606(Homo sapiens skin) - 2013/08/12 2014/10/16 rogid:X+cUOat5/4dAu1URlD51JvVR9yU9606 rogid:TSuCh5lL8Vv86lLm4iOqyYBXGRw9606 intact-crc:BD36253A7FAA56F0|rigid:7qguBbWHkWOSAiWXMfuWoFYj6Hk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)