#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9P2M4	uniprotkb:Q15907	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	intact:EBI-722234|uniprotkb:Q2YDT2|uniprotkb:Q8NI07|uniprotkb:B2R7I4|uniprotkb:D6W671|uniprotkb:A5YM50|uniprotkb:Q5U0I1|uniprotkb:Q6FHR0|uniprotkb:Q6FI42|uniprotkb:B4DMK0|ensembl:ENSP00000333547	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:rb11b_human(display_long)|uniprotkb:GTP-binding protein YPT3(gene name synonym)|uniprotkb:RAB11B(gene name)|psi-mi:RAB11B(display_short)|uniprotkb:YPT3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8753952|imex:IM-22127-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	refseq:NP_004209.2|dip:DIP-50898N|ensembl:ENSG00000185236(gene)|ensembl:ENST00000328024(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0045054"(constitutive secretory pathway)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q15907|rcsb pdb:2F9L|rcsb pdb:2F9M|rcsb pdb:4OJK|reactome:R-HSA-8854214|reactome:R-HSA-8873719	-	-	-	figure legend:Figure 4 D|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	rogid:+fsu7NPmd5fgoe0TE67IcISlscA9606	intact-crc:42B7F94EB16B5C35|rigid:8K+K5aqz5mLb0+RAKa8mvKvmQso	false	myc tag:?-?	mutation decreasing interaction strength:25-25|green fluorescent protein tag:?-?|mutation increasing interaction strength:70-70	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75154	uniprotkb:Q9P2M4	intact:EBI-7942186|uniprotkb:B1AHQ0|uniprotkb:Q9H155|intact:MINT-6799564|uniprotkb:Q7Z5E9|uniprotkb:B4DEI7|uniprotkb:B0QYT8|uniprotkb:Q4VXV7|uniprotkb:B4DZR6|uniprotkb:Q9NUI0|uniprotkb:Q9H1G0|uniprotkb:B0QYI8|ensembl:ENSP00000262305|ensembl:ENSP00000482156	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	psi-mi:rfip3_human(display_long)|uniprotkb:RAB11FIP3(gene name)|psi-mi:RAB11FIP3(display_short)|uniprotkb:KIAA0665(gene name synonym)|uniprotkb:EF hands-containing Rab-interacting protein(gene name synonym)|uniprotkb:ARFO1(gene name synonym)|uniprotkb:Arfophilin-1(gene name synonym)|uniprotkb:MU-MB-17.148(gene name synonym)	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:"MI:0096"(pull down)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8758503|imex:IM-22127-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011521066.1|refseq:NP_001135744.1|refseq:NP_055515.1|refseq:XP_005255770.1|refseq:XP_005255772.1|dip:DIP-47494N|ensembl:ENSG00000090565(gene)|ensembl:ENSG00000275338(gene)|ensembl:ENST00000262305(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000611004(transcript)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070164"(negative regulation of adiponectin secretion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR019018|interpro:IPR032920|interpro:IPR037245|mint:O75154|rcsb pdb:2D7C|rcsb pdb:2HV8|rcsb pdb:4D0M|rcsb pdb:4UJ3|rcsb pdb:4UJ4|reactome:R-HSA-5620916|go:"GO:0043231"(intracellular membrane-bounded organelle)	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	-	comment:mint	-	figure legend:Figure 4 C|comment:"Author states: However, small amounts of TBC1D14 were detected bound to GST-FIP3, and substantially higher amounts of TBC1D14 were bound to GST-FIP3 in the presence of activated Rab11bQ70A."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:WhfTHiaO0UsZkmVPGHmOb64IsXQ9606	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	intact-crc:9CAA374659135E32|rigid:dJcTHs7+2KReutEchmX3I2dunTg	false	binding-associated region:300-756	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9P2M4	uniprotkb:O75385	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8752761|imex:IM-22127-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903	-	-	-	figure legend:Figure S2 B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/30	2014/10/16	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606	intact-crc:8C65D18B49D9ABF0|rigid:BpSdL82unEojGG4g4M7Q7uGYIFU	false	mutation:472-472	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62491	uniprotkb:Q9P2M4	intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym)	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:"MI:0018"(two hybrid)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8753433|imex:IM-22127-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	-	-	-	figure legend:Figure 4 A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/30	2014/10/16	rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	intact-crc:1CE01E910BA63CFA|rigid:hi5ugMBmdnb8CM/MBGRRPtCgeLU	false	-	mutation:472-472	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P2M4	uniprotkb:Q15907	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	intact:EBI-722234|uniprotkb:Q2YDT2|uniprotkb:Q8NI07|uniprotkb:B2R7I4|uniprotkb:D6W671|uniprotkb:A5YM50|uniprotkb:Q5U0I1|uniprotkb:Q6FHR0|uniprotkb:Q6FI42|uniprotkb:B4DMK0|ensembl:ENSP00000333547	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:rb11b_human(display_long)|uniprotkb:GTP-binding protein YPT3(gene name synonym)|uniprotkb:RAB11B(gene name)|psi-mi:RAB11B(display_short)|uniprotkb:YPT3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8758461|imex:IM-22127-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	refseq:NP_004209.2|dip:DIP-50898N|ensembl:ENSG00000185236(gene)|ensembl:ENST00000328024(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0045054"(constitutive secretory pathway)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q15907|rcsb pdb:2F9L|rcsb pdb:2F9M|rcsb pdb:4OJK|reactome:R-HSA-8854214|reactome:R-HSA-8873719	-	-	-	figure legend:Figure 4 A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/30	2014/10/16	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	rogid:+fsu7NPmd5fgoe0TE67IcISlscA9606	intact-crc:18D34C88D3968EED|rigid:8K+K5aqz5mLb0+RAKa8mvKvmQso	false	mutation:472-472	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75385	uniprotkb:Q9P2M4	intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym)	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8746777|imex:IM-22127-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	-	-	-	figure legend:Figure S2 C & D|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	intact-crc:1D1DDE207C184B4C|rigid:BpSdL82unEojGG4g4M7Q7uGYIFU	false	ha tag:?-?	green fluorescent protein tag:?-?|necessary binding region:224-669(IPR000195)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9P2M4	uniprotkb:O75385	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8752621|imex:IM-22127-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903	go:"GO:0005776"(autophagosome)	-	-	figure legend:Figure 2A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606	intact-crc:658C27B019F0F435|rigid:BpSdL82unEojGG4g4M7Q7uGYIFU	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:O75143	uniprotkb:Q9P2M4	intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym)	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8754410|imex:IM-22127-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	go:"GO:0055037"(recycling endosome)	-	-	figure legend:Figure 7 A|comment:Alexa Fluor 647-Tfn also colocalized with TBC1D14 and Atg13. However, its source could not be traced.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	intact-crc:7CD84FCFD8F3A6EC|rigid:eof9iIwoJh5UmNVlZenz1Bwamj4	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:P02786	uniprotkb:Q9P2M4	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8754461|imex:IM-22127-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	-	-	-	figure legend:Figure 7 B & C|comment:"Authors state: We quantified the extent of colocalization of overexpressed GFP-TBC1D14 and TfnR and found that the colocalization of TfnR-positive REs with GFP-TBC1D14 was independent of starvation."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	intact-crc:99A117F58F0B9BB5|rigid:I5Tq3Wc8zmf4KinJScMeOMoN5dw	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:Q7Z3C6	uniprotkb:P02786	intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710	intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197	psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym)	psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8754553|imex:IM-22127-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852	refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N	go:"GO:0055038"(recycling endosome membrane)	-	-	figure legend:Figure 8 A, B, C, D & E|comment:"Author states: The colocalization of ULK1 and TfnR was unaffected by starvation."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:arvq+TjXETr14g/FkOITnLfYVh89606	rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606	intact-crc:9ABC53424B2856F3|rigid:jGxZkvaPSLxy4L+CAngTFRz8FIU	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:Q7Z3C6	uniprotkb:O75385	intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710	intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560	psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym)	psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8754553|imex:IM-22127-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852	refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903	go:"GO:0055038"(recycling endosome membrane)	-	-	figure legend:Figure 8 A, B, C, D & E|comment:"Author states: The colocalization of ULK1 and TfnR was unaffected by starvation."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:arvq+TjXETr14g/FkOITnLfYVh89606	rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606	intact-crc:9ABC53424B2856F3|rigid:jGxZkvaPSLxy4L+CAngTFRz8FIU	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:Q9P2M4	uniprotkb:O75385	intact:EBI-2797718|uniprotkb:E9PAZ6|uniprotkb:Q8NDK3|uniprotkb:Q8IW15|uniprotkb:D3DVT4|uniprotkb:B9A6L5|ensembl:ENSP00000386921|ensembl:ENSP00000404041	intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560	psi-mi:tbc14_human(display_long)|uniprotkb:KIAA1322(gene name synonym)|uniprotkb:TBC1D14(gene name)|psi-mi:TBC1D14(display_short)	psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Longatti et al. (2012)	pubmed:22613832|imex:IM-22127	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8753175|imex:IM-22127-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273734.1|refseq:NP_001106832.1|refseq:NP_001106834.1|refseq:NP_065824.2|refseq:XP_006713958.1|ensembl:ENSG00000132405(gene)|ensembl:ENST00000409757(transcript)|ensembl:ENST00000448507(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055037"(recycling endosome)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:2QQ8|reactome:R-HSA-8854214|refseq:NP_001317567.1	refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903	-	-	-	figure legend:Figure 2 D E & F.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/08/30	2014/10/16	rogid:McWkCZDFfkR1cVQHBJ3yj2PvsP09606	rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606	intact-crc:82894B9008163974|rigid:BpSdL82unEojGG4g4M7Q7uGYIFU	false	green fluorescent protein tag:?-?|necessary binding region:224-330	myc tag:?-?|necessary binding region:429-828	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)