#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02884 uniprotkb:P38874 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6559544|wwpdb:4EJS|imex:IM-20530-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 - crc64:276F0D1538EAA8FA crc64:DFD93D7BA583E2F5 figure legend:Fig. 1b, Fig. 3c, Fig. 3d, Suppl. Table S1|3d-resolution:2.61A|3d-r-factors:working 17.4%, free 22.4%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:99B9B3B0B59801D2|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372 sufficient binding region:1-238 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:Q04868 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6559544|wwpdb:4EJS|imex:IM-20530-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:276F0D1538EAA8FA crc64:1A5062465AF67F47 figure legend:Fig. 1b, Fig. 3c, Fig. 3d, Suppl. Table S1|3d-resolution:2.61A|3d-r-factors:working 17.4%, free 22.4%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:99B9B3B0B59801D2|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372 - 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:P38874 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6559654|imex:IM-20530-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 - crc64:276F0D1538EAA8FA crc64:DFD93D7BA583E2F5 figure legend:Fig. 3a, Fig. 3b, Suppl. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:7957959A0C389144|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372 sufficient binding region:1-238 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:Q04868 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6559654|imex:IM-20530-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:276F0D1538EAA8FA crc64:1A5062465AF67F47 figure legend:Fig. 3a, Fig. 3b, Suppl. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:7957959A0C389144|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372 - 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:P38874 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6621434|imex:IM-20530-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 - crc64:276F0D1538EAA8FA crc64:DFD93D7BA583E2F5 figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:2C8FFEC975290C7C|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372|mutation:293-293,302-302 sufficient binding region:1-238 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:Q04868 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6621434|imex:IM-20530-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:276F0D1538EAA8FA crc64:1A5062465AF67F47 figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:2C8FFEC975290C7C|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372|mutation:293-293,302-302 - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02884 uniprotkb:P38874 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6621040|imex:IM-20530-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 - crc64:276F0D1538EAA8FA crc64:DFD93D7BA583E2F5 figure legend:Suppl. Fig. 1c, Suppl. Fig. 1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:9402D8DD15FA9108|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372 sufficient binding region:1-238 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q02884 uniprotkb:Q04868 intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6621040|imex:IM-20530-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:276F0D1538EAA8FA crc64:1A5062465AF67F47 figure legend:Suppl. Fig. 1c, Suppl. Fig. 1d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:9402D8DD15FA9108|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false sufficient binding region:67-372 - 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04868 uniprotkb:Q02884 intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6621415|imex:IM-20530-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:1A5062465AF67F47 crc64:276F0D1538EAA8FA figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/03/21 2014/10/16 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 intact-crc:1CA3ECAAA60D2171|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q04868 uniprotkb:P38874 intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6621415|imex:IM-20530-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 - crc64:1A5062465AF67F47 crc64:DFD93D7BA583E2F5 figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/03/21 2014/10/16 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:1CA3ECAAA60D2171|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q04868 uniprotkb:Q04868 intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6621415|imex:IM-20530-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:1A5062465AF67F47 crc64:1A5062465AF67F47 figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/03/21 2014/10/16 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:1CA3ECAAA60D2171|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q04868 uniprotkb:Q02884 intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6622142|imex:IM-20530-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:1A5062465AF67F47 crc64:276F0D1538EAA8FA figure legend:Fig. 4|comment:"Less Myc-Elp6 co-precipitates with GFP-Elp6 when Elp4 is mutated (his293ala-phe302ala mutant), indicating that this mutation disrupts dimerization of the Elp4-Elp5-Elp6 heterotrimer."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/03/21 2014/10/16 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 intact-crc:7475522AC128571D|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false green fluorescent protein tag:?-? mutation:293-293,302-302|myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q04868 uniprotkb:P38874 intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6622142|imex:IM-20530-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 - crc64:1A5062465AF67F47 crc64:DFD93D7BA583E2F5 figure legend:Fig. 4|comment:"Less Myc-Elp6 co-precipitates with GFP-Elp6 when Elp4 is mutated (his293ala-phe302ala mutant), indicating that this mutation disrupts dimerization of the Elp4-Elp5-Elp6 heterotrimer."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/03/21 2014/10/16 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:7475522AC128571D|rigid:wbH1mwX1y2jHIhI1x0A2lTOaxf0 false green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61830 uniprotkb:Q02884 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-35277|uniprotkb:D6W3R5|ensemblfungi:YPL101W psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:elp4_yeast(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:Gamma-toxin target 7(gene name synonym)|uniprotkb:HAT-associated protein 1(gene name synonym)|uniprotkb:YPL101W(locus name)|uniprotkb:HAP1(gene name synonym)|uniprotkb:TOT7(gene name synonym) psi-mi:"MI:0096"(pull down) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6622160|imex:IM-20530-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_015224.1|sgd:S000006022|mint:Q02884|dip:DIP-6718N|ensemblfungi:YPL101W(gene)|ensemblfungi:YPL101W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:A6115FEB480AC67A crc64:276F0D1538EAA8FA figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:LLHmiDxhPIIxIElMn9yVWoFnY4Q559292 intact-crc:0692C044E8DCF1C3|rigid:E8JAelo0PdAZjDEZj0z0fbSnboQ false sufficient binding region:1-28|glutathione s tranferase tag:28-28 mutation decreasing interaction:293-293,302-302|myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61830 uniprotkb:P38874 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-9061|ensemblfungi:YHR187W|uniprotkb:D3DLD5 psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:elp5_yeast(display_long)|uniprotkb:YHR187W(locus name)|uniprotkb:IKI1(gene name)|psi-mi:IKI1(display_short)|uniprotkb:ELP5(gene name synonym)|uniprotkb:HAP2(gene name synonym)|uniprotkb:TOT5(gene name synonym)|uniprotkb:Gamma-toxin target 5(gene name synonym)|uniprotkb:Protein IKI1(gene name synonym)|uniprotkb:HAT-associated protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6622160|imex:IM-20530-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G sgd:S000001230|ensemblfungi:YHR187W(gene)|ensemblfungi:YHR187W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR019519|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS|refseq:NP_012057.3|dip:DIP-1967N|mint:P38874 - crc64:A6115FEB480AC67A crc64:DFD93D7BA583E2F5 figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:Xl/ausdL/d79OM78at6ZZldvBMg559292 intact-crc:0692C044E8DCF1C3|rigid:E8JAelo0PdAZjDEZj0z0fbSnboQ false sufficient binding region:1-28|glutathione s tranferase tag:28-28 myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61830 uniprotkb:Q04868 intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C intact:EBI-27653|uniprotkb:D6W0D9|ensemblfungi:YMR312W psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short) psi-mi:elp6_yeast(display_long)|uniprotkb:YMR312W(locus name)|uniprotkb:YM9924.04(orf name)|uniprotkb:ELP6(gene name)|psi-mi:ELP6(display_short)|uniprotkb:HAP3(gene name synonym)|uniprotkb:TOT6(gene name synonym)|uniprotkb:Gamma-toxin target 6(gene name synonym)|uniprotkb:HAT-associated protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Lin et al. (2012) pubmed:22556426|imex:IM-20530 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6622160|imex:IM-20530-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G refseq:NP_014043.1|sgd:S000004929|dip:DIP-1966N|mint:Q04868|ensemblfungi:YMR312W(gene)|ensemblfungi:YMR312W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032447"(protein urmylation)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR018627|interpro:IPR027417|rcsb pdb:4A8J|rcsb pdb:4EJS - crc64:A6115FEB480AC67A crc64:1A5062465AF67F47 figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/21 2014/10/16 rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292 rogid:Nyp6/02bMFUoG//crZCg98Eepc8559292 intact-crc:0692C044E8DCF1C3|rigid:E8JAelo0PdAZjDEZj0z0fbSnboQ false sufficient binding region:1-28|glutathione s tranferase tag:28-28 myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)