#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P30958 uniprotkb:P0A698 intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 intact:EBI-552091|uniprotkb:P07671|uniprotkb:P76788|uniprotkb:Q2M6P6|ensemblbacteria:AAC77028|ensemblbacteria:BAE78060 psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:uvra_ecoli(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:dinE(gene name synonym)|uniprotkb:b4058(locus name)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:JW4019(locus name) psi-mi:"MI:0114"(x-ray crystallography) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9004938|wwpdb:4dfc|imex:IM-21769-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ refseq:NP_418482.1|refseq:WP_000357740.1|dip:DIP-35876N|ensemblbacteria:AAC77028(transcript)|ensemblbacteria:b4058(gene)|ensemblbacteria:BAE78060(gene)|ensemblbacteria:BAE78060(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003439(ABC transporter-like)|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR017871|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552|rcsb pdb:4DFC - - - figure legend:Table S1|3d-r-factors:Rwork = 0.24, Rfree = 0.28|3d-resolution:2.8 A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 rogid:OKjfkRoH1Hiss54GfWRhLI6MPcg83333 intact-crc:B32D119B18265D33|rigid:MgEpyYsR6iE3rVxtlpYTTNzadW0 false sufficient binding region:127-213 sufficient binding region:131-250 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A698 uniprotkb:P30958 intact:EBI-552091|uniprotkb:P07671|uniprotkb:P76788|uniprotkb:Q2M6P6|ensemblbacteria:AAC77028|ensemblbacteria:BAE78060 intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 psi-mi:uvra_ecoli(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:dinE(gene name synonym)|uniprotkb:b4058(locus name)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:JW4019(locus name) psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:"MI:0096"(pull down) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9005583|imex:IM-21769-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418482.1|refseq:WP_000357740.1|dip:DIP-35876N|ensemblbacteria:AAC77028(transcript)|ensemblbacteria:b4058(gene)|ensemblbacteria:BAE78060(gene)|ensemblbacteria:BAE78060(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003439(ABC transporter-like)|interpro:IPR004602(Excinuclease ABC, A subunit)|interpro:IPR017871|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552|rcsb pdb:4DFC refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ - - - figure legend:Fig. S1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 rogid:OKjfkRoH1Hiss54GfWRhLI6MPcg83333 rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 intact-crc:539078141BFF22E8|rigid:MgEpyYsR6iE3rVxtlpYTTNzadW0 false sufficient binding region:131-250 sufficient binding region:127-213|his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) chebi:"CHEBI:15422" uniprotkb:P30958 intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:"MI:0826"(x ray scattering) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9005795|imex:IM-21769-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ - - - figure legend:Fig 3b, S6a, S6b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 - rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 intact-crc:E9CAB5F316868FE4 false - sufficient binding region:479-1148|mutation:730-730|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16761" uniprotkb:P30958 intact:EBI-1188073 intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long) psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:"MI:0826"(x ray scattering) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9005895|imex:IM-21769-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ - - - figure legend:Fig 3b, S6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 - rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 intact-crc:CBD32B40A2E41313 false - mutation:730-730|his tag:n-n|sufficient binding region:479-1148 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:15422" uniprotkb:P30958 intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:"MI:0880"(atpase assay) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0882"(atpase reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9006277|imex:IM-21769-11 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ go:"GO:0016887"(ATP hydrolysis activity) - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 - rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 intact-crc:E28D304002FD6B1C false - mutation decreasing interaction rate:527-527,1031-1031|mutation decreasing interaction rate:1051-1051,167-167|mutation disrupting interaction rate:730-730|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:15422" chebi:"CHEBI:15422" intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:"MI:0030"(cross-linking study) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9007503|imex:IM-21769-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - go:"GO:0016887"(ATP hydrolysis activity) - - figure legend:Fig. S2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 - - intact-crc:7F2838ED67ACFC5C false - 32p radiolabel:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:15422" uniprotkb:P30958 intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:"MI:0030"(cross-linking study) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9007503|imex:IM-21769-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ go:"GO:0016887"(ATP hydrolysis activity) - - figure legend:Fig. S2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 - rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 intact-crc:7F2838ED67ACFC5C false - his tag:n-n - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:15422" uniprotkb:P30958 intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249" intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name) psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:"MI:0030"(cross-linking study) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9082768|imex:IM-21769-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ go:"GO:0016887"(ATP hydrolysis activity) - - figure legend:Fig. S2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 - rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 intact-crc:2CD2583764929039 false 32p radiolabel:?-? his tag:n-n - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P30958 uniprotkb:A5PJB8 intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 intact:EBI-9007630|uniprotkb:E1BDT3|ensembl:ENSBTAP00000050246 psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:a5pjb8_bovin(display_long)|uniprotkb:CTRB1(gene name)|psi-mi:CTRB1(display_short)|uniprotkb:LOC618826(gene name synonym) psi-mi:"MI:0435"(protease assay) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-9007680|imex:IM-21769-8 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ refseq:NP_001098924.1|ensembl:ENSBTAG00000039914(gene)|ensembl:ENSBTAT00000053990(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006508"(proteolysis)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|reactome:R-BTA-1592389|reactome:R-BTA-196741 go:"GO:0006508"(proteolysis) - - figure legend:Fig. S3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2014/10/16 rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 rogid:S6a30MKlD12CAQ9jd4Q2HfmT4JA9913 intact-crc:4A3296CB13F1BF3F|rigid:tYcvWd0pb7AKPe3cn4OGWeQPb88 false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P00780 uniprotkb:P30958 intact:EBI-8090218|intact:MINT-1505000|uniprotkb:Q9F943 intact:EBI-554211|uniprotkb:P77592|ensemblbacteria:AAC74198|ensemblbacteria:BAA35929 psi-mi:subc_bacli(display_long)|uniprotkb:subC(gene name)|psi-mi:subC(display_short)|uniprotkb:apr(gene name synonym) psi-mi:mfd_ecoli(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:b1114(locus name)|uniprotkb:JW1100(locus name) psi-mi:"MI:0435"(protease assay) Deaconescu et al. (2012) pubmed:22331906|imex:IM-21769 taxid:1402(bacli)|taxid:1402(Bacillus licheniformis) taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0570"(protein cleavage) psi-mi:"MI:0469"(IntAct) intact:EBI-9007661|imex:IM-21769-6 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034202|rcsb pdb:1AVT|rcsb pdb:1SCN|rcsb pdb:1BE6|rcsb pdb:1YU6|rcsb pdb:1BFU|rcsb pdb:1BFK|rcsb pdb:1BE8|rcsb pdb:2SEC|interpro:IPR022398|interpro:IPR015500(Peptidase S8, subtilisin-related)|rcsb pdb:3UNX|rcsb pdb:1SBC|rcsb pdb:1AV7|rcsb pdb:2WUW|rcsb pdb:1SEL|interpro:IPR023828|rcsb pdb:2WUV|rcsb pdb:1SCA|rcsb pdb:1AF4|rcsb pdb:1SCD|interpro:IPR023827|rcsb pdb:1SCB|rcsb pdb:1OYV|rcsb pdb:1CSE|rcsb pdb:1R0R|rcsb pdb:3VSB|rcsb pdb:1VSB|rcsb pdb:1C3L|rcsb pdb:4C3U|rcsb pdb:4C3V|interpro:IPR036852|interpro:IPR037045|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR010259(Proteinase inhibitor I9, subtilisin propeptide)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6DWQ refseq:NP_415632.1|refseq:WP_001115094.1|dip:DIP-10199N|ensemblbacteria:AAC74198(transcript)|ensemblbacteria:b1114(gene)|ensemblbacteria:BAA35929(gene)|ensemblbacteria:BAA35929(transcript)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:2B2N|rcsb pdb:2EYQ|rcsb pdb:3HJH|rcsb pdb:4DFC|rcsb pdb:6XEO|rcsb pdb:6YHZ go:"GO:0006508"(proteolysis) function:Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides|comment:mint - figure legend:Fig. S3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/02 2019/09/20 rogid:nrQRFfDqi8EpoAZTJRh31jk/gks1402 rogid:ZcNsbIM/6DMXJzQ5MrvxXayy0IM83333 intact-crc:93395CD7C4C21F07|rigid:encmY2lwv6GGj53QhTF8xPxMljU false - his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)