#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99MK8	uniprotkb:Q9QXZ9	intact:EBI-771762|uniprotkb:Q99LL8|ensembl:ENSMUSP00000086114	intact:EBI-6902193|ensembl:ENSMUSP00000022331|uniprotkb:A4QPG3|uniprotkb:B2C712	psi-mi:arbk1_mouse(display_long)|uniprotkb:Grk2(gene name)|psi-mi:Grk2(display_short)|uniprotkb:Adrbk1(gene name synonym)|uniprotkb:G-protein-coupled receptor kinase 2(gene name synonym)	psi-mi:opn4_mouse(display_long)|uniprotkb:Opn4(gene name)|psi-mi:Opn4(display_short)|uniprotkb:Mop(gene name synonym)|uniprotkb:Mopn(gene name synonym)|uniprotkb:Opsin-4(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Blasic et al. (2012)	imex:IM-20979|pubmed:22159583	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6902246|imex:IM-20979-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277747.1|dip:DIP-32413N|ensembl:ENSMUSG00000024858(gene)|ensembl:ENSMUST00000088737(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0003108"(negative regulation of the force of heart contraction by chemical signal)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007217"(tachykinin receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0010661"(positive regulation of muscle cell apoptotic process)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019079"(viral genome replication)|go:"GO:0030424"(axon)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0031850"(delta-type opioid receptor binding)|go:"GO:0031851"(kappa-type opioid receptor binding)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0042311"(vasodilation)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1901081"(negative regulation of relaxation of smooth muscle)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|mint:Q99MK8|reactome:R-MMU-111933|reactome:R-MMU-416476|reactome:R-MMU-418555|reactome:R-MMU-5635838|reactome:R-MMU-8856825	go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-MMU-416476|reactome:R-MMU-419771|go:"GO:1990384"(hyaloid vascular plexus regression)|ensembl:ENSMUSG00000021799(gene)|ensembl:ENSMUST00000022331(transcript)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0048511"(rhythmic process)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0071482"(cellular response to light stimulus)|refseq:NP_001122071.1|refseq:NP_038915.1	-	-	-	figure legend:8i|comment:"Colocalisation was found in retinal ganglion cells (RGCs)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina)	-	2013/07/25	2014/10/16	rogid:boMMNI7l5ABURK9gD6uoeiJy7z810090	rogid:q1R6uZA7YBH+KQCTuGmsYrs657A10090	intact-crc:9DC9B9491C3753E6|rigid:PxvDej9uCeIYdMMO7FNUjiTPQDw	false	-	-	-	-	psi-mi:"MI:1198"(immunohistochemistry)	psi-mi:"MI:1198"(immunohistochemistry)
uniprotkb:Q9QXZ9	uniprotkb:Q3UYH7	intact:EBI-6902193|ensembl:ENSMUSP00000022331|uniprotkb:A4QPG3|uniprotkb:B2C712	intact:EBI-6903286|ensembl:ENSMUSP00000070445|uniprotkb:F8VPM8	psi-mi:opn4_mouse(display_long)|uniprotkb:Opn4(gene name)|psi-mi:Opn4(display_short)|uniprotkb:Mop(gene name synonym)|uniprotkb:Mopn(gene name synonym)|uniprotkb:Opsin-4(gene name synonym)	psi-mi:arbk2_mouse(display_long)|uniprotkb:Adrbk2(gene name)|psi-mi:Adrbk2(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Blasic et al. (2012)	imex:IM-20979|pubmed:22159583	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6902236|imex:IM-20979-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-MMU-416476|reactome:R-MMU-419771|go:"GO:1990384"(hyaloid vascular plexus regression)|ensembl:ENSMUSG00000021799(gene)|ensembl:ENSMUST00000022331(transcript)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0048511"(rhythmic process)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0071482"(cellular response to light stimulus)|refseq:NP_001122071.1|refseq:NP_038915.1	refseq:NP_001272735.1|ensembl:ENSMUSG00000042249(gene)|ensembl:ENSMUST00000065167(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0031623"(receptor internalization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046154"(rhodopsin metabolic process)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|reactome:R-MMU-418555|reactome:R-MMU-8856825|interpro:IPR011009(Protein kinase-like)|refseq:NP_796052.2	-	-	-	figure legend:8|comment:"Colocalisation was found in retinal ganglion cells (RGCs)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina)	-	2013/07/25	2014/10/16	rogid:q1R6uZA7YBH+KQCTuGmsYrs657A10090	rogid:m47GkeIFhWFm0T6NfQfcZcIvqUM10090	intact-crc:23EBB681BBCE133C|rigid:PIQSBEWBXq6YPWcRzWgYJ+t3kqg	false	-	-	-	-	psi-mi:"MI:1198"(immunohistochemistry)	psi-mi:"MI:1198"(immunohistochemistry)
uniprotkb:Q9QXZ9	uniprotkb:P35626	intact:EBI-6902193|ensembl:ENSMUSP00000022331|uniprotkb:A4QPG3|uniprotkb:B2C712	intact:EBI-2875868|ensembl:ENSP00000317578|uniprotkb:Q9UGW9	psi-mi:opn4_mouse(display_long)|uniprotkb:Opn4(gene name)|psi-mi:Opn4(display_short)|uniprotkb:Mop(gene name synonym)|uniprotkb:Mopn(gene name synonym)|uniprotkb:Opsin-4(gene name synonym)	psi-mi:arbk2_human(display_long)|uniprotkb:GRK3(gene name)|psi-mi:GRK3(display_short)|uniprotkb:ADRBK2(gene name synonym)|uniprotkb:BARK2(gene name synonym)|uniprotkb:G-protein-coupled receptor kinase 3(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Blasic et al. (2012)	imex:IM-20979|pubmed:22159583	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6902190|imex:IM-20979-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-MMU-416476|reactome:R-MMU-419771|go:"GO:1990384"(hyaloid vascular plexus regression)|ensembl:ENSMUSG00000021799(gene)|ensembl:ENSMUST00000022331(transcript)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0048511"(rhythmic process)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0071482"(cellular response to light stimulus)|refseq:NP_001122071.1|refseq:NP_038915.1	go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0031623"(receptor internalization)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0005886"(plasma membrane)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|reactome:R-HSA-418555|reactome:R-HSA-8856825|ensembl:ENSG00000100077(gene)|ensembl:ENST00000324198(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|refseq:NP_005151.2	-	-	-	figure legend:6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/07/25	2014/10/16	rogid:q1R6uZA7YBH+KQCTuGmsYrs657A10090	rogid:IXh7IeKOJ35sBT4TzFHPNB1xhnE9606	intact-crc:FED28E274FEC3351|rigid:snBTx6zjU7RuLRXHQjosNHthluQ	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9QXZ9	uniprotkb:P25098	intact:EBI-6902193|ensembl:ENSMUSP00000022331|uniprotkb:A4QPG3|uniprotkb:B2C712	intact:EBI-3904795|uniprotkb:Q6GTT3|uniprotkb:B0ZBE1|uniprotkb:Q13837|ensembl:ENSP00000312262	psi-mi:opn4_mouse(display_long)|uniprotkb:Opn4(gene name)|psi-mi:Opn4(display_short)|uniprotkb:Mop(gene name synonym)|uniprotkb:Mopn(gene name synonym)|uniprotkb:Opsin-4(gene name synonym)	psi-mi:arbk1_human(display_long)|uniprotkb:GRK2(gene name)|psi-mi:GRK2(display_short)|uniprotkb:ADRBK1(gene name synonym)|uniprotkb:BARK(gene name synonym)|uniprotkb:BARK1(gene name synonym)|uniprotkb:G-protein coupled receptor kinase 2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Blasic et al. (2012)	imex:IM-20979|pubmed:22159583	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6902190|imex:IM-20979-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|reactome:R-MMU-416476|reactome:R-MMU-419771|go:"GO:1990384"(hyaloid vascular plexus regression)|ensembl:ENSMUSG00000021799(gene)|ensembl:ENSMUST00000022331(transcript)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007634"(optokinetic behavior)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043052"(thermotaxis)|go:"GO:0043204"(perikaryon)|go:"GO:0048511"(rhythmic process)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0071482"(cellular response to light stimulus)|refseq:NP_001122071.1|refseq:NP_038915.1	refseq:NP_001610.2|dip:DIP-42429N|ensembl:ENSG00000173020(gene)|ensembl:ENST00000308595(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0003108"(negative regulation of the force of heart contraction by chemical signal)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007217"(tachykinin receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019079"(viral genome replication)|go:"GO:0031623"(receptor internalization)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0005737"(cytoplasm)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1901081"(negative regulation of relaxation of smooth muscle)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|mint:P25098|rcsb pdb:1BAK|rcsb pdb:3CIK|rcsb pdb:3KRW|rcsb pdb:3KRX|rcsb pdb:3V5W|rcsb pdb:4MK0|rcsb pdb:4PNK|rcsb pdb:5HE1|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UUU|rcsb pdb:5UVC|rcsb pdb:5WG3|rcsb pdb:5WG4|rcsb pdb:5WG5|rcsb pdb:6C2Y|rcsb pdb:6U7C|rcsb pdb:7K7L|rcsb pdb:7K7Z|reactome:R-HSA-111933|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-5635838|reactome:R-HSA-8856825|go:"GO:0045202"(synapse)	-	-	-	figure legend:6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/07/25	2014/10/16	rogid:q1R6uZA7YBH+KQCTuGmsYrs657A10090	rogid:iAd5kj9koCtmmVivrWfgN4y0YMc9606	intact-crc:FED28E274FEC3351|rigid:snBTx6zjU7RuLRXHQjosNHthluQ	false	tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)