#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8IUD2-2 uniprotkb:Q8R0S4 intact:EBI-6920871|ensembl:ENSP00000410064 intact:EBI-3647752|uniprotkb:Q3UHK2|uniprotkb:Q8BRN6|uniprotkb:Q8CAJ9|ensembl:ENSMUSP00000077438 psi-mi:q8iud2-2(display_long)|uniprotkb:ELKS beta(isoform synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym)|uniprotkb:Rab6-interacting protein 2(gene name synonym) psi-mi:cacb4_mouse(display_long)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short)|uniprotkb:Cacnlb4(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Billings et al. (2012) imex:IM-21128|pubmed:22107844 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6920882|imex:IM-21128-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082805(gene)|ensembl:ENST00000440394(transcript)|intact:EBI-1044755(isoform-parent) refseq:NP_001272356.1|refseq:XP_011237317.1|refseq:NP_001032176.1|refseq:NP_666235.1|refseq:XP_006497704.1|go:"GO:0045202"(synapse)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|reactome:R-MMU-112308|go:"GO:0042391"(regulation of membrane potential)|ensembl:ENSMUSG00000017412(gene)|ensembl:ENSMUST00000078324(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|refseq:XP_017170652.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/08/07 2014/10/16 rogid:kjgvTvz3akg340xuVNdXMRNogyU9606 rogid:a2B9SMgAy84Ou3mK3Q6aniE71vQ10090 intact-crc:5B189F5B2E632B97|rigid:+iq/5u73QBlKqY/MmhC72yqKSRE false flag tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IUD2-2 uniprotkb:Q8R0S4 intact:EBI-6920871|ensembl:ENSP00000410064 intact:EBI-3647752|uniprotkb:Q3UHK2|uniprotkb:Q8BRN6|uniprotkb:Q8CAJ9|ensembl:ENSMUSP00000077438 psi-mi:q8iud2-2(display_long)|uniprotkb:ELKS beta(isoform synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym)|uniprotkb:Rab6-interacting protein 2(gene name synonym) psi-mi:cacb4_mouse(display_long)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short)|uniprotkb:Cacnlb4(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Billings et al. (2012) imex:IM-21128|pubmed:22107844 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6920901|imex:IM-21128-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000082805(gene)|ensembl:ENST00000440394(transcript)|intact:EBI-1044755(isoform-parent) refseq:NP_001272356.1|refseq:XP_011237317.1|refseq:NP_001032176.1|refseq:NP_666235.1|refseq:XP_006497704.1|go:"GO:0045202"(synapse)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|reactome:R-MMU-112308|go:"GO:0042391"(regulation of membrane potential)|ensembl:ENSMUSG00000017412(gene)|ensembl:ENSMUST00000078324(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|refseq:XP_017170652.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/08/07 2014/10/16 rogid:kjgvTvz3akg340xuVNdXMRNogyU9606 rogid:a2B9SMgAy84Ou3mK3Q6aniE71vQ10090 intact-crc:55C2365DFAA2FE9F|rigid:+iq/5u73QBlKqY/MmhC72yqKSRE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)