#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:17202" uniprotkb:Q9P2T1 intact:EBI-9007843|chebi:"CHEBI:5849"|chebi:"CHEBI:12057"|chebi:"CHEBI:12063"|chebi:"CHEBI:13372"|chebi:"CHEBI:13373"|chebi:"CHEBI:14457"|chebi:"CHEBI:19271"|chebi:"CHEBI:43418"|chebi:"CHEBI:43475"|chebi:"CHEBI:43524"|chebi:"CHEBI:43528"|chebi:"CHEBI:43563"|chebi:"CHEBI:43611"|chebi:"CHEBI:781325"|chebi:"CHEBI:47501" intact:EBI-2806548|uniprotkb:Q567T0|uniprotkb:Q6IAJ8|uniprotkb:D3DS66|ensembl:ENSP00000347449|ensembl:ENSP00000382369|ensembl:ENSP00000453299|ensembl:ENSP00000494224|ensembl:ENSP00000495583|ensembl:ENSP00000496504|uniprotkb:Q86T14 psi-mi:imp(display_short)|psi-mi:"CHEBI:17202"(display_long)|intact:2'-inosine-5'-monophosphate(synonym)|intact:5'-IMP(synonym)|intact:5'-Inosinate(synonym)|intact:5'-Inosine monophosphate(synonym)|intact:5'-Inosinic acid(synonym)|intact:hypoxanthosine 5'-monophosphate(synonym)|intact:IMP(synonym)|intact:Inosine 5'-monophosphate(synonym)|intact:Inosine 5'-phosphate(synonym)|intact:Inosine monophosphate(synonym)|intact:inosinic acid(synonym)|intact:Inosinic acid(synonym)|intact:ribosylhypoxanthine monophosphate(synonym)|intact:5'-inosinic acid(iupac name) psi-mi:gmpr2_human(display_long)|uniprotkb:Guanosine 5'-monophosphate oxidoreductase 2(gene name synonym)|uniprotkb:GMPR2(gene name)|psi-mi:GMPR2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Patton et al. (2011) imex:IM-21795|pubmed:22037469 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9005594|pubmed:2C6Q|imex:IM-21795-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001269950.1|refseq:NP_001269951.1|refseq:NP_001269952.1|refseq:NP_001002000.1|refseq:NP_001002001.1|refseq:NP_001002002.1|refseq:NP_057660.2|ensembl:ENSG00000100938(gene)|ensembl:ENSG00000284752(gene)|ensembl:ENST00000355299(transcript)|ensembl:ENST00000399440(transcript)|ensembl:ENST00000559836(transcript)|ensembl:ENST00000642276(transcript)|ensembl:ENST00000644066(transcript)|ensembl:ENST00000647320(transcript)|go:"GO:0003920"(GMP reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0046037"(GMP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1902560"(GMP reductase complex)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:2A7R|rcsb pdb:2BZN|rcsb pdb:2C6Q|reactome:R-HSA-74217|interpro:IPR005993(Guanosine monophosphate reductase 1) - inchi key:GRSZFWQUAKGDAV-KQYNXXCUSA-N - figure legend:suppl. fig 6b|3d-resolution:1.70 A|3d-r-factors:"R-factor: 0.165, R-free: 0.206"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2014/10/16 - rogid:/k9kNXIA6CIiiNIhpdrXTrR5wE89606 intact-crc:814390074109400A false - sufficient binding region:10-341 8 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16474" uniprotkb:Q9P2T1 intact:EBI-8785164|chebi:"CHEBI:44286"|chebi:"CHEBI:7425"|chebi:"CHEBI:13399"|chebi:"CHEBI:13400"|chebi:"CHEBI:21904"|chebi:"CHEBI:175555" intact:EBI-2806548|uniprotkb:Q567T0|uniprotkb:Q6IAJ8|uniprotkb:D3DS66|ensembl:ENSP00000347449|ensembl:ENSP00000382369|ensembl:ENSP00000453299|ensembl:ENSP00000494224|ensembl:ENSP00000495583|ensembl:ENSP00000496504|uniprotkb:Q86T14 psi-mi:nadph(display_short)|psi-mi:"CHEBI:16474"(display_long)|intact:dihydronicotinamide-adenine dinucleotide phosphate(synonym)|intact:NADPH(synonym)|intact:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE(synonym)|intact:reduced nicotinamide-adenine dinucleotide phosphate(synonym)|intact:TPNH(synonym)|intact:"2'-O-phosphonoadenosine 5'-{3-[1-(3-carbamoyl-1,4-dihydropyridin-1-yl)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate}"(iupac name) psi-mi:gmpr2_human(display_long)|uniprotkb:Guanosine 5'-monophosphate oxidoreductase 2(gene name synonym)|uniprotkb:GMPR2(gene name)|psi-mi:GMPR2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Patton et al. (2011) imex:IM-21795|pubmed:22037469 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9005594|pubmed:2C6Q|imex:IM-21795-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001269950.1|refseq:NP_001269951.1|refseq:NP_001269952.1|refseq:NP_001002000.1|refseq:NP_001002001.1|refseq:NP_001002002.1|refseq:NP_057660.2|ensembl:ENSG00000100938(gene)|ensembl:ENSG00000284752(gene)|ensembl:ENST00000355299(transcript)|ensembl:ENST00000399440(transcript)|ensembl:ENST00000559836(transcript)|ensembl:ENST00000642276(transcript)|ensembl:ENST00000644066(transcript)|ensembl:ENST00000647320(transcript)|go:"GO:0003920"(GMP reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0046037"(GMP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1902560"(GMP reductase complex)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:2A7R|rcsb pdb:2BZN|rcsb pdb:2C6Q|reactome:R-HSA-74217|interpro:IPR005993(Guanosine monophosphate reductase 1) - inchi key:ACFIXJIJDZMPPO-NNYOXOHSSA-N - figure legend:suppl. fig 6b|3d-resolution:1.70 A|3d-r-factors:"R-factor: 0.165, R-free: 0.206"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2014/10/16 - rogid:/k9kNXIA6CIiiNIhpdrXTrR5wE89606 intact-crc:814390074109400A false - sufficient binding region:10-341 7 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:17202" uniprotkb:Q9P2T1 intact:EBI-9007843|chebi:"CHEBI:5849"|chebi:"CHEBI:12057"|chebi:"CHEBI:12063"|chebi:"CHEBI:13372"|chebi:"CHEBI:13373"|chebi:"CHEBI:14457"|chebi:"CHEBI:19271"|chebi:"CHEBI:43418"|chebi:"CHEBI:43475"|chebi:"CHEBI:43524"|chebi:"CHEBI:43528"|chebi:"CHEBI:43563"|chebi:"CHEBI:43611"|chebi:"CHEBI:781325"|chebi:"CHEBI:47501" intact:EBI-2806548|uniprotkb:Q567T0|uniprotkb:Q6IAJ8|uniprotkb:D3DS66|ensembl:ENSP00000347449|ensembl:ENSP00000382369|ensembl:ENSP00000453299|ensembl:ENSP00000494224|ensembl:ENSP00000495583|ensembl:ENSP00000496504|uniprotkb:Q86T14 psi-mi:imp(display_short)|psi-mi:"CHEBI:17202"(display_long)|intact:2'-inosine-5'-monophosphate(synonym)|intact:5'-IMP(synonym)|intact:5'-Inosinate(synonym)|intact:5'-Inosine monophosphate(synonym)|intact:5'-Inosinic acid(synonym)|intact:hypoxanthosine 5'-monophosphate(synonym)|intact:IMP(synonym)|intact:Inosine 5'-monophosphate(synonym)|intact:Inosine 5'-phosphate(synonym)|intact:Inosine monophosphate(synonym)|intact:inosinic acid(synonym)|intact:Inosinic acid(synonym)|intact:ribosylhypoxanthine monophosphate(synonym)|intact:5'-inosinic acid(iupac name) psi-mi:gmpr2_human(display_long)|uniprotkb:Guanosine 5'-monophosphate oxidoreductase 2(gene name synonym)|uniprotkb:GMPR2(gene name)|psi-mi:GMPR2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Patton et al. (2011) imex:IM-21795|pubmed:22037469 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9007836|pdbe:2BZN|imex:IM-21795-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001269950.1|refseq:NP_001269951.1|refseq:NP_001269952.1|refseq:NP_001002000.1|refseq:NP_001002001.1|refseq:NP_001002002.1|refseq:NP_057660.2|ensembl:ENSG00000100938(gene)|ensembl:ENSG00000284752(gene)|ensembl:ENST00000355299(transcript)|ensembl:ENST00000399440(transcript)|ensembl:ENST00000559836(transcript)|ensembl:ENST00000642276(transcript)|ensembl:ENST00000644066(transcript)|ensembl:ENST00000647320(transcript)|go:"GO:0003920"(GMP reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0046037"(GMP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1902560"(GMP reductase complex)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:2A7R|rcsb pdb:2BZN|rcsb pdb:2C6Q|reactome:R-HSA-74217|interpro:IPR005993(Guanosine monophosphate reductase 1) - inchi key:GRSZFWQUAKGDAV-KQYNXXCUSA-N - figure legend:suppl. fig 6|3d-resolution:2.15 A|3d-r-factors:"R-factor: 0.161, R-free: 0.210"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2019/01/30 - rogid:/k9kNXIA6CIiiNIhpdrXTrR5wE89606 intact-crc:76E07FCF52A859CE false - sufficient binding region:10-341 8 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)