#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03343 uniprotkb:Q9Z266 intact:EBI-8754302 intact:EBI-6170320|ensembl:ENSMUSP00000122090|uniprotkb:Q3U8V4|uniprotkb:Q922V7 psi-mi:adcy6_rat(display_long)|uniprotkb:Adcy6(gene name)|psi-mi:Adcy6(display_short)|uniprotkb:ATP pyrophosphate-lyase 6(gene name synonym)|uniprotkb:Adenylate cyclase type VI(gene name synonym)|uniprotkb:Adenylyl cyclase 6(gene name synonym)|uniprotkb:"Ca(2+)-inhibitable adenylyl cyclase"(gene name synonym) psi-mi:snapn_mouse(display_long)|uniprotkb:Snapin(gene name)|psi-mi:Snapin(display_short)|uniprotkb:Snap25bp(gene name synonym)|uniprotkb:Snapap(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)|uniprotkb:Bloc1s7(gene name synonym) psi-mi:"MI:0096"(pull down) Wu et al. (2011) pubmed:21986494|imex:IM-21383 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8760866|imex:IM-21383-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032628|refseq:NP_036953.4|interpro:IPR030672|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR018297|interpro:IPR009398(Adenylate cyclase-like)|rgd:2035|interpro:IPR029787|reactome:R-RNO-163615|go:"GO:0000149"(SNARE binding)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008294"(calcium- and calmodulin-responsive adenylate cyclase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904322"(cellular response to forskolin)|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-400042|reactome:R-RNO-418597|reactome:R-RNO-5610787 ensembl:ENSMUSG00000001018(gene)|ensembl:ENSMUST00000149884(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|mint:Q9Z266|reactome:R-MMU-432722|refseq:NP_598615.1 - - - figure legend:7A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)") - 2013/09/03 2014/10/16 rogid:WCkazznu2efV8jfzpub4ijg6YiU10116 rogid:L66mKyBsv3V0+K6AhcHvc540uX810090 intact-crc:1F8DEA6E9138EC78|rigid:+ZC0sXxDxk99nbqJPjLmmW4XRaY false flag tag:?-?|fc-igg tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03343 uniprotkb:P60879 intact:EBI-8754302 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:adcy6_rat(display_long)|uniprotkb:Adcy6(gene name)|psi-mi:Adcy6(display_short)|uniprotkb:ATP pyrophosphate-lyase 6(gene name synonym)|uniprotkb:Adenylate cyclase type VI(gene name synonym)|uniprotkb:Adenylyl cyclase 6(gene name synonym)|uniprotkb:"Ca(2+)-inhibitable adenylyl cyclase"(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0096"(pull down) Wu et al. (2011) pubmed:21986494|imex:IM-21383 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8760866|imex:IM-21383-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032628|refseq:NP_036953.4|interpro:IPR030672|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR018297|interpro:IPR009398(Adenylate cyclase-like)|rgd:2035|interpro:IPR029787|reactome:R-RNO-163615|go:"GO:0000149"(SNARE binding)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008294"(calcium- and calmodulin-responsive adenylate cyclase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904322"(cellular response to forskolin)|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-400042|reactome:R-RNO-418597|reactome:R-RNO-5610787 refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N - - - figure legend:7A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)") - 2013/09/03 2014/10/16 rogid:WCkazznu2efV8jfzpub4ijg6YiU10116 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:1F8DEA6E9138EC78|rigid:+ZC0sXxDxk99nbqJPjLmmW4XRaY false flag tag:?-?|fc-igg tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03343 uniprotkb:P60879 intact:EBI-8754302 intact:EBI-445270|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:A2AIC2|uniprotkb:A2AIC3|ensembl:ENSMUSP00000028727 psi-mi:adcy6_rat(display_long)|uniprotkb:Adcy6(gene name)|psi-mi:Adcy6(display_short)|uniprotkb:ATP pyrophosphate-lyase 6(gene name synonym)|uniprotkb:Adenylate cyclase type VI(gene name synonym)|uniprotkb:Adenylyl cyclase 6(gene name synonym)|uniprotkb:"Ca(2+)-inhibitable adenylyl cyclase"(gene name synonym) psi-mi:snp25_mouse(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym) psi-mi:"MI:0096"(pull down) Wu et al. (2011) pubmed:21986494|imex:IM-21383 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8754282|imex:IM-21383-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032628|refseq:NP_036953.4|interpro:IPR030672|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR018297|interpro:IPR009398(Adenylate cyclase-like)|rgd:2035|interpro:IPR029787|reactome:R-RNO-163615|go:"GO:0000149"(SNARE binding)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008294"(calcium- and calmodulin-responsive adenylate cyclase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904322"(cellular response to forskolin)|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-400042|reactome:R-RNO-418597|reactome:R-RNO-5610787 refseq:NP_001277985.1|refseq:NP_035558.1|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60879|rcsb pdb:2BU0|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|go:"GO:0045121"(membrane raft)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|reactome:R-MMU-6798695|reactome:R-MMU-888590|reactome:R-MMU-449836|refseq:XP_017172247.1|refseq:XP_017172249.1|reactome:R-MMU-264642|ensembl:ENSMUST00000028727(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|ensembl:ENSMUSG00000027273(gene)|go:"GO:0007616"(long-term memory)|dip:DIP-29066N - - - figure legend:7B|comment:Snapin S50A, which had no interaction with Snap25, prevented the pulldown of Snap25 by Fc-AC6.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)") - 2013/09/03 2014/10/16 rogid:WCkazznu2efV8jfzpub4ijg6YiU10116 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10090 intact-crc:1A119F24BDAF86B0|rigid:+ZC0sXxDxk99nbqJPjLmmW4XRaY false fc-igg tag:c-c|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03343 uniprotkb:Q9Z266 intact:EBI-8754302 intact:EBI-6170320|ensembl:ENSMUSP00000122090|uniprotkb:Q3U8V4|uniprotkb:Q922V7 psi-mi:adcy6_rat(display_long)|uniprotkb:Adcy6(gene name)|psi-mi:Adcy6(display_short)|uniprotkb:ATP pyrophosphate-lyase 6(gene name synonym)|uniprotkb:Adenylate cyclase type VI(gene name synonym)|uniprotkb:Adenylyl cyclase 6(gene name synonym)|uniprotkb:"Ca(2+)-inhibitable adenylyl cyclase"(gene name synonym) psi-mi:snapn_mouse(display_long)|uniprotkb:Snapin(gene name)|psi-mi:Snapin(display_short)|uniprotkb:Snap25bp(gene name synonym)|uniprotkb:Snapap(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)|uniprotkb:Bloc1s7(gene name synonym) psi-mi:"MI:0096"(pull down) Wu et al. (2011) pubmed:21986494|imex:IM-21383 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8754282|imex:IM-21383-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032628|refseq:NP_036953.4|interpro:IPR030672|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR018297|interpro:IPR009398(Adenylate cyclase-like)|rgd:2035|interpro:IPR029787|reactome:R-RNO-163615|go:"GO:0000149"(SNARE binding)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008294"(calcium- and calmodulin-responsive adenylate cyclase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1904322"(cellular response to forskolin)|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-400042|reactome:R-RNO-418597|reactome:R-RNO-5610787 ensembl:ENSMUSG00000001018(gene)|ensembl:ENSMUST00000149884(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|mint:Q9Z266|reactome:R-MMU-432722|refseq:NP_598615.1 - - - figure legend:7B|comment:Snapin S50A, which had no interaction with Snap25, prevented the pulldown of Snap25 by Fc-AC6.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)") - 2013/09/03 2014/10/16 rogid:WCkazznu2efV8jfzpub4ijg6YiU10116 rogid:L66mKyBsv3V0+K6AhcHvc540uX810090 intact-crc:1A119F24BDAF86B0|rigid:+ZC0sXxDxk99nbqJPjLmmW4XRaY false fc-igg tag:c-c|flag tag:?-? mutation decreasing interaction:50-50|myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)