#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WVC8 uniprotkb:P26361 intact:EBI-6895537|uniprotkb:B2RTD9|ensembl:ENSMUSP00000001254 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 psi-mi:s26a3_mouse(display_long)|uniprotkb:Slc26a3(gene name)|psi-mi:Slc26a3(display_short)|uniprotkb:Dra(gene name synonym)|uniprotkb:Down-regulated in adenoma(gene name synonym)|uniprotkb:Solute carrier family 26 member 3(gene name synonym) psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6895558|imex:IM-21140-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067328.1|refseq:XP_017170439.1|ensembl:ENSMUSG00000001225(gene)|ensembl:ENSMUST00000001254(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0031526"(brush border membrane)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097225"(sperm midpiece)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030321|interpro:IPR036513|rcsb pdb:5DOW|reactome:R-MMU-427601 refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 - - - figure legend:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:N62pf5vy6XC1Oecss4jBnYvykxs10090 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 intact-crc:999677A7576C47E9|rigid:Y0gFxvfoc9zUbYEU4+6XzZMViH4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P26361 uniprotkb:Q8CIW6 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 intact:EBI-6895517|ensembl:ENSMUSP00000140849|uniprotkb:E9Q4D3|uniprotkb:Q3TQD3|uniprotkb:Q812E2|uniprotkb:Q8CJD0|uniprotkb:Q8K142|uniprotkb:Q923J3 psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:s26a6_mouse(display_long)|uniprotkb:Slc26a6(gene name)|psi-mi:Slc26a6(display_short)|uniprotkb:Anion exchange transporter(gene name synonym)|uniprotkb:Cfex(gene name synonym)|uniprotkb:Chloride-formate exchanger(gene name synonym)|uniprotkb:Pat1(gene name synonym)|uniprotkb:Pendrin-L1(gene name synonym)|uniprotkb:Pendrin-like protein 1(gene name synonym)|uniprotkb:Putative anion transporter-1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6895533|imex:IM-21140-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0008272"(sulfate transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015499"(formate transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015660"(formate efflux transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0015724"(formate transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0019532"(oxalate transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046724"(oxalic acid secretion)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097225"(sperm midpiece)|ensembl:ENSMUSG00000023259(gene)|ensembl:ENSMUST00000188557(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030323|interpro:IPR036513|reactome:R-MMU-427601|refseq:NP_599252.2 - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 rogid:3UGOy4VpK68Gw7KluLs5K1ZK5TQ10090 intact-crc:4C4955C5A2B8F9B6|rigid:feuEO0ZoZ9xcbwxbmGVz3JC7SII false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P26361 uniprotkb:P70441 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6895509|imex:IM-21140-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 - - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 intact-crc:96D3F391CBF37D0F|rigid:5uh53/tr3mWQNaDwGl/RE8KlsJs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9WVC8 uniprotkb:P26361 intact:EBI-6895537|uniprotkb:B2RTD9|ensembl:ENSMUSP00000001254 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 psi-mi:s26a3_mouse(display_long)|uniprotkb:Slc26a3(gene name)|psi-mi:Slc26a3(display_short)|uniprotkb:Dra(gene name synonym)|uniprotkb:Down-regulated in adenoma(gene name synonym)|uniprotkb:Solute carrier family 26 member 3(gene name synonym) psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895953|imex:IM-21140-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067328.1|refseq:XP_017170439.1|ensembl:ENSMUSG00000001225(gene)|ensembl:ENSMUST00000001254(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0031526"(brush border membrane)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097225"(sperm midpiece)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030321|interpro:IPR036513|rcsb pdb:5DOW|reactome:R-MMU-427601 refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:N62pf5vy6XC1Oecss4jBnYvykxs10090 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 intact-crc:A6479565690E482A|rigid:Y0gFxvfoc9zUbYEU4+6XzZMViH4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CIW6 uniprotkb:Q9WVC8 intact:EBI-6895517|ensembl:ENSMUSP00000140849|uniprotkb:E9Q4D3|uniprotkb:Q3TQD3|uniprotkb:Q812E2|uniprotkb:Q8CJD0|uniprotkb:Q8K142|uniprotkb:Q923J3 intact:EBI-6895537|uniprotkb:B2RTD9|ensembl:ENSMUSP00000001254 psi-mi:s26a6_mouse(display_long)|uniprotkb:Slc26a6(gene name)|psi-mi:Slc26a6(display_short)|uniprotkb:Anion exchange transporter(gene name synonym)|uniprotkb:Cfex(gene name synonym)|uniprotkb:Chloride-formate exchanger(gene name synonym)|uniprotkb:Pat1(gene name synonym)|uniprotkb:Pendrin-L1(gene name synonym)|uniprotkb:Pendrin-like protein 1(gene name synonym)|uniprotkb:Putative anion transporter-1(gene name synonym) psi-mi:s26a3_mouse(display_long)|uniprotkb:Slc26a3(gene name)|psi-mi:Slc26a3(display_short)|uniprotkb:Dra(gene name synonym)|uniprotkb:Down-regulated in adenoma(gene name synonym)|uniprotkb:Solute carrier family 26 member 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895945|imex:IM-21140-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0008272"(sulfate transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015499"(formate transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015660"(formate efflux transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0015724"(formate transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0019532"(oxalate transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046724"(oxalic acid secretion)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097225"(sperm midpiece)|ensembl:ENSMUSG00000023259(gene)|ensembl:ENSMUST00000188557(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030323|interpro:IPR036513|reactome:R-MMU-427601|refseq:NP_599252.2 refseq:NP_067328.1|refseq:XP_017170439.1|ensembl:ENSMUSG00000001225(gene)|ensembl:ENSMUST00000001254(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0031526"(brush border membrane)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097225"(sperm midpiece)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030321|interpro:IPR036513|rcsb pdb:5DOW|reactome:R-MMU-427601 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:3UGOy4VpK68Gw7KluLs5K1ZK5TQ10090 rogid:N62pf5vy6XC1Oecss4jBnYvykxs10090 intact-crc:D21F246C9C60CDCD|rigid:uF9MHOUtWIqD0XVhkFTiDQPQyUw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVC8 uniprotkb:P70441 intact:EBI-6895537|uniprotkb:B2RTD9|ensembl:ENSMUSP00000001254 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 psi-mi:s26a3_mouse(display_long)|uniprotkb:Slc26a3(gene name)|psi-mi:Slc26a3(display_short)|uniprotkb:Dra(gene name synonym)|uniprotkb:Down-regulated in adenoma(gene name synonym)|uniprotkb:Solute carrier family 26 member 3(gene name synonym) psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895949|imex:IM-21140-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067328.1|refseq:XP_017170439.1|ensembl:ENSMUSG00000001225(gene)|ensembl:ENSMUST00000001254(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0031526"(brush border membrane)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097225"(sperm midpiece)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030321|interpro:IPR036513|rcsb pdb:5DOW|reactome:R-MMU-427601 refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:N62pf5vy6XC1Oecss4jBnYvykxs10090 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 intact-crc:931EF0075C70A9C5|rigid:LWvpkN//yfcjqSaCS1bcZtxA34I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CIW6 uniprotkb:P26361 intact:EBI-6895517|ensembl:ENSMUSP00000140849|uniprotkb:E9Q4D3|uniprotkb:Q3TQD3|uniprotkb:Q812E2|uniprotkb:Q8CJD0|uniprotkb:Q8K142|uniprotkb:Q923J3 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 psi-mi:s26a6_mouse(display_long)|uniprotkb:Slc26a6(gene name)|psi-mi:Slc26a6(display_short)|uniprotkb:Anion exchange transporter(gene name synonym)|uniprotkb:Cfex(gene name synonym)|uniprotkb:Chloride-formate exchanger(gene name synonym)|uniprotkb:Pat1(gene name synonym)|uniprotkb:Pendrin-L1(gene name synonym)|uniprotkb:Pendrin-like protein 1(gene name synonym)|uniprotkb:Putative anion transporter-1(gene name synonym) psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895965|imex:IM-21140-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0008272"(sulfate transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015499"(formate transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015660"(formate efflux transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0015724"(formate transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0019532"(oxalate transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046724"(oxalic acid secretion)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097225"(sperm midpiece)|ensembl:ENSMUSG00000023259(gene)|ensembl:ENSMUST00000188557(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030323|interpro:IPR036513|reactome:R-MMU-427601|refseq:NP_599252.2 refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:3UGOy4VpK68Gw7KluLs5K1ZK5TQ10090 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 intact-crc:7398B7079CDAF675|rigid:feuEO0ZoZ9xcbwxbmGVz3JC7SII false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVC8 uniprotkb:Q8CIW6 intact:EBI-6895537|uniprotkb:B2RTD9|ensembl:ENSMUSP00000001254 intact:EBI-6895517|ensembl:ENSMUSP00000140849|uniprotkb:E9Q4D3|uniprotkb:Q3TQD3|uniprotkb:Q812E2|uniprotkb:Q8CJD0|uniprotkb:Q8K142|uniprotkb:Q923J3 psi-mi:s26a3_mouse(display_long)|uniprotkb:Slc26a3(gene name)|psi-mi:Slc26a3(display_short)|uniprotkb:Dra(gene name synonym)|uniprotkb:Down-regulated in adenoma(gene name synonym)|uniprotkb:Solute carrier family 26 member 3(gene name synonym) psi-mi:s26a6_mouse(display_long)|uniprotkb:Slc26a6(gene name)|psi-mi:Slc26a6(display_short)|uniprotkb:Anion exchange transporter(gene name synonym)|uniprotkb:Cfex(gene name synonym)|uniprotkb:Chloride-formate exchanger(gene name synonym)|uniprotkb:Pat1(gene name synonym)|uniprotkb:Pendrin-L1(gene name synonym)|uniprotkb:Pendrin-like protein 1(gene name synonym)|uniprotkb:Putative anion transporter-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895957|imex:IM-21140-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067328.1|refseq:XP_017170439.1|ensembl:ENSMUSG00000001225(gene)|ensembl:ENSMUST00000001254(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0031526"(brush border membrane)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097225"(sperm midpiece)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030321|interpro:IPR036513|rcsb pdb:5DOW|reactome:R-MMU-427601 go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0008272"(sulfate transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015499"(formate transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015660"(formate efflux transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0015724"(formate transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0019532"(oxalate transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046724"(oxalic acid secretion)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097225"(sperm midpiece)|ensembl:ENSMUSG00000023259(gene)|ensembl:ENSMUST00000188557(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030323|interpro:IPR036513|reactome:R-MMU-427601|refseq:NP_599252.2 - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:N62pf5vy6XC1Oecss4jBnYvykxs10090 rogid:3UGOy4VpK68Gw7KluLs5K1ZK5TQ10090 intact-crc:F797B86E11FCC802|rigid:uF9MHOUtWIqD0XVhkFTiDQPQyUw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CIW6 uniprotkb:P70441 intact:EBI-6895517|ensembl:ENSMUSP00000140849|uniprotkb:E9Q4D3|uniprotkb:Q3TQD3|uniprotkb:Q812E2|uniprotkb:Q8CJD0|uniprotkb:Q8K142|uniprotkb:Q923J3 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 psi-mi:s26a6_mouse(display_long)|uniprotkb:Slc26a6(gene name)|psi-mi:Slc26a6(display_short)|uniprotkb:Anion exchange transporter(gene name synonym)|uniprotkb:Cfex(gene name synonym)|uniprotkb:Chloride-formate exchanger(gene name synonym)|uniprotkb:Pat1(gene name synonym)|uniprotkb:Pendrin-L1(gene name synonym)|uniprotkb:Pendrin-like protein 1(gene name synonym)|uniprotkb:Putative anion transporter-1(gene name synonym) psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895961|imex:IM-21140-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0008272"(sulfate transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015499"(formate transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015660"(formate efflux transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0015724"(formate transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0019532"(oxalate transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046724"(oxalic acid secretion)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097225"(sperm midpiece)|ensembl:ENSMUSG00000023259(gene)|ensembl:ENSMUST00000188557(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030323|interpro:IPR036513|reactome:R-MMU-427601|refseq:NP_599252.2 refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:3UGOy4VpK68Gw7KluLs5K1ZK5TQ10090 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 intact-crc:46C1D265A9A4179A|rigid:g4MSZP5z1q4kCXulWJYRrihuBik false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70441 uniprotkb:Q9WVC8 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 intact:EBI-6895537|uniprotkb:B2RTD9|ensembl:ENSMUSP00000001254 psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:s26a3_mouse(display_long)|uniprotkb:Slc26a3(gene name)|psi-mi:Slc26a3(display_short)|uniprotkb:Dra(gene name synonym)|uniprotkb:Down-regulated in adenoma(gene name synonym)|uniprotkb:Solute carrier family 26 member 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895992|imex:IM-21140-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 refseq:NP_067328.1|refseq:XP_017170439.1|ensembl:ENSMUSG00000001225(gene)|ensembl:ENSMUST00000001254(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0031526"(brush border membrane)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097225"(sperm midpiece)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030321|interpro:IPR036513|rcsb pdb:5DOW|reactome:R-MMU-427601 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 rogid:N62pf5vy6XC1Oecss4jBnYvykxs10090 intact-crc:B697DC05D1ECAC0A|rigid:LWvpkN//yfcjqSaCS1bcZtxA34I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26361 uniprotkb:P70441 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895978|imex:IM-21140-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 intact-crc:A9021153F59172CC|rigid:5uh53/tr3mWQNaDwGl/RE8KlsJs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CIW6 uniprotkb:P70441 intact:EBI-6895517|ensembl:ENSMUSP00000140849|uniprotkb:E9Q4D3|uniprotkb:Q3TQD3|uniprotkb:Q812E2|uniprotkb:Q8CJD0|uniprotkb:Q8K142|uniprotkb:Q923J3 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 psi-mi:s26a6_mouse(display_long)|uniprotkb:Slc26a6(gene name)|psi-mi:Slc26a6(display_short)|uniprotkb:Anion exchange transporter(gene name synonym)|uniprotkb:Cfex(gene name synonym)|uniprotkb:Chloride-formate exchanger(gene name synonym)|uniprotkb:Pat1(gene name synonym)|uniprotkb:Pendrin-L1(gene name synonym)|uniprotkb:Pendrin-like protein 1(gene name synonym)|uniprotkb:Putative anion transporter-1(gene name synonym) psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895988|imex:IM-21140-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0008272"(sulfate transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015499"(formate transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015660"(formate efflux transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0015724"(formate transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0019532"(oxalate transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046724"(oxalic acid secretion)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097225"(sperm midpiece)|ensembl:ENSMUSG00000023259(gene)|ensembl:ENSMUST00000188557(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030323|interpro:IPR036513|reactome:R-MMU-427601|refseq:NP_599252.2 refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:3UGOy4VpK68Gw7KluLs5K1ZK5TQ10090 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 intact-crc:634A2E6724381255|rigid:g4MSZP5z1q4kCXulWJYRrihuBik false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26361 uniprotkb:P70441 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6896004|imex:IM-21140-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 intact-crc:8C8C4D51780D7703|rigid:5uh53/tr3mWQNaDwGl/RE8KlsJs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WVC8 uniprotkb:P26361 intact:EBI-6895537|uniprotkb:B2RTD9|ensembl:ENSMUSP00000001254 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 psi-mi:s26a3_mouse(display_long)|uniprotkb:Slc26a3(gene name)|psi-mi:Slc26a3(display_short)|uniprotkb:Dra(gene name synonym)|uniprotkb:Down-regulated in adenoma(gene name synonym)|uniprotkb:Solute carrier family 26 member 3(gene name synonym) psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6895996|imex:IM-21140-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067328.1|refseq:XP_017170439.1|ensembl:ENSMUSG00000001225(gene)|ensembl:ENSMUST00000001254(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0031526"(brush border membrane)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097225"(sperm midpiece)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030321|interpro:IPR036513|rcsb pdb:5DOW|reactome:R-MMU-427601 refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:N62pf5vy6XC1Oecss4jBnYvykxs10090 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 intact-crc:83CAA967E4924DE5|rigid:Y0gFxvfoc9zUbYEU4+6XzZMViH4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8CIW6 uniprotkb:P26361 intact:EBI-6895517|ensembl:ENSMUSP00000140849|uniprotkb:E9Q4D3|uniprotkb:Q3TQD3|uniprotkb:Q812E2|uniprotkb:Q8CJD0|uniprotkb:Q8K142|uniprotkb:Q923J3 intact:EBI-6115317|uniprotkb:Q63893|uniprotkb:Q63894|uniprotkb:Q9JKQ6|ensembl:ENSMUSP00000049228 psi-mi:s26a6_mouse(display_long)|uniprotkb:Slc26a6(gene name)|psi-mi:Slc26a6(display_short)|uniprotkb:Anion exchange transporter(gene name synonym)|uniprotkb:Cfex(gene name synonym)|uniprotkb:Chloride-formate exchanger(gene name synonym)|uniprotkb:Pat1(gene name synonym)|uniprotkb:Pendrin-L1(gene name synonym)|uniprotkb:Pendrin-like protein 1(gene name synonym)|uniprotkb:Putative anion transporter-1(gene name synonym) psi-mi:cftr_mouse(display_long)|uniprotkb:Cftr(gene name)|psi-mi:Cftr(display_short)|uniprotkb:Abcc7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:cAMP-dependent chloride channel(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chávez et al. (2012) pubmed:21976599|imex:IM-21140 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6896000|imex:IM-21140-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0008272"(sulfate transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015499"(formate transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015660"(formate efflux transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0015724"(formate transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019531"(oxalate transmembrane transporter activity)|go:"GO:0019532"(oxalate transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046724"(oxalic acid secretion)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097225"(sperm midpiece)|ensembl:ENSMUSG00000023259(gene)|ensembl:ENSMUST00000188557(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|interpro:IPR030323|interpro:IPR036513|reactome:R-MMU-427601|refseq:NP_599252.2 refseq:NP_066388.1|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0106138"(Sec61 translocon complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904446"(positive regulation of establishment of Sertoli cell barrier)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:2000077"(negative regulation of type B pancreatic cell development)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR025837|interpro:IPR027417|interpro:IPR036640|mint:P26361|rcsb pdb:1Q3H|rcsb pdb:1R0W|ensembl:ENSMUSG00000041301(gene)|ensembl:ENSMUST00000045706(transcript)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006821"(chloride transport)|go:"GO:0006833"(water transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030324"(lung development)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042311"(vasodilation)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|refseq:XP_006505040.1|refseq:XP_006505041.1|dip:DIP-29618N|reactome:R-MMU-8856828|reactome:R-MMU-9013406|reactome:R-MMU-9646399|reactome:R-MMU-8856825|rcsb pdb:1R0X|rcsb pdb:1R0Y|rcsb pdb:1R0Z|rcsb pdb:1R10|rcsb pdb:1XF9|rcsb pdb:1XFA|rcsb pdb:3SI7|reactome:R-MMU-382556|reactome:R-MMU-5627083|reactome:R-MMU-5689880 - - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/07/16 2014/10/16 rogid:3UGOy4VpK68Gw7KluLs5K1ZK5TQ10090 rogid:DkfDbDUFD82LoluVzldqf0AJbhQ10090 intact-crc:56175B051146F3BA|rigid:feuEO0ZoZ9xcbwxbmGVz3JC7SII false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)