#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O15350-1	uniprotkb:Q9UKL3	intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545	intact:EBI-2339650|uniprotkb:Q6PH76|uniprotkb:Q9NZV9|uniprotkb:Q86YD9|uniprotkb:Q9P2N1|uniprotkb:Q9NUQ4|uniprotkb:Q7LCQ7|uniprotkb:Q9Y563|uniprotkb:A2RUB7|uniprotkb:E1P553	psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:c8ap2_human(display_long)|uniprotkb:CASP8AP2(gene name)|psi-mi:CASP8AP2(display_short)|uniprotkb:FLASH(gene name synonym)|uniprotkb:KIAA1315(gene name synonym)|uniprotkb:RIP25(gene name synonym)|uniprotkb:FLICE-associated huge protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	De et al. (2012)	pubmed:21725362|imex:IM-18630	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6480968|imex:IM-18630-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)	refseq:NP_001131139.1|refseq:NP_001131140.1|refseq:NP_036247.1|mint:Q9UKL3|dip:DIP-40986N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016505"(peptidase activator activity involved in apoptotic process)|go:"GO:0016605"(PML body)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR009057(Homeodomain-like)|interpro:IPR039674|rcsb pdb:2LR8|rcsb pdb:6ANO|rcsb pdb:6AOZ|rcsb pdb:6AP0|reactome:R-HSA-3899300	-	-	-	figure legend:4a,b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/01/18	2014/10/16	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rogid:MRT84GftrXoJmhrsnUtfJGFhPQQ9606	intact-crc:81B817DC88E3FD29|rigid:KbeoMySifbxIdtYhf5pIB+WSOHc	false	ha tag:?-?|sufficient binding region:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UKL3	uniprotkb:O15350-3	intact:EBI-2339650|uniprotkb:Q6PH76|uniprotkb:Q9NZV9|uniprotkb:Q86YD9|uniprotkb:Q9P2N1|uniprotkb:Q9NUQ4|uniprotkb:Q7LCQ7|uniprotkb:Q9Y563|uniprotkb:A2RUB7|uniprotkb:E1P553	intact:EBI-6480997	psi-mi:c8ap2_human(display_long)|uniprotkb:CASP8AP2(gene name)|psi-mi:CASP8AP2(display_short)|uniprotkb:FLASH(gene name synonym)|uniprotkb:KIAA1315(gene name synonym)|uniprotkb:RIP25(gene name synonym)|uniprotkb:FLICE-associated huge protein(gene name synonym)	psi-mi:o15350-3(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	De et al. (2012)	pubmed:21725362|imex:IM-18630	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6481006|imex:IM-18630-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001131139.1|refseq:NP_001131140.1|refseq:NP_036247.1|mint:Q9UKL3|dip:DIP-40986N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016505"(peptidase activator activity involved in apoptotic process)|go:"GO:0016605"(PML body)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR009057(Homeodomain-like)|interpro:IPR039674|rcsb pdb:2LR8|rcsb pdb:6ANO|rcsb pdb:6AOZ|rcsb pdb:6AP0|reactome:R-HSA-3899300	intact:EBI-389606(isoform-parent)	-	-	isoform-comment:Produced by alternative splicing of isoform Alpha. The splicing of exon 11 results in a frameshift from the original reading frame.	figure legend:4a|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/01/18	2014/10/16	rogid:MRT84GftrXoJmhrsnUtfJGFhPQQ9606	rogid:Ivp4huF71E61prZKia63X6lAl9k9606	intact-crc:60DC882BA2639EE2|rigid:IjvyxvqDwUjqCTKnBg9cP5DuDk4	false	green fluorescent protein tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UKL3	uniprotkb:O15350-1	intact:EBI-2339650|uniprotkb:Q6PH76|uniprotkb:Q9NZV9|uniprotkb:Q86YD9|uniprotkb:Q9P2N1|uniprotkb:Q9NUQ4|uniprotkb:Q7LCQ7|uniprotkb:Q9Y563|uniprotkb:A2RUB7|uniprotkb:E1P553	intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545	psi-mi:c8ap2_human(display_long)|uniprotkb:CASP8AP2(gene name)|psi-mi:CASP8AP2(display_short)|uniprotkb:FLASH(gene name synonym)|uniprotkb:KIAA1315(gene name synonym)|uniprotkb:RIP25(gene name synonym)|uniprotkb:FLICE-associated huge protein(gene name synonym)	psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	De et al. (2012)	pubmed:21725362|imex:IM-18630	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6481047|imex:IM-18630-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001131139.1|refseq:NP_001131140.1|refseq:NP_036247.1|mint:Q9UKL3|dip:DIP-40986N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0016505"(peptidase activator activity involved in apoptotic process)|go:"GO:0016605"(PML body)|go:"GO:0032184"(SUMO polymer binding)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR009057(Homeodomain-like)|interpro:IPR039674|rcsb pdb:2LR8|rcsb pdb:6ANO|rcsb pdb:6AOZ|rcsb pdb:6AP0|reactome:R-HSA-3899300	intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)	-	-	-	figure legend:4b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/01/18	2014/10/16	rogid:MRT84GftrXoJmhrsnUtfJGFhPQQ9606	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	intact-crc:60DE58E3FD299EE2|rigid:KbeoMySifbxIdtYhf5pIB+WSOHc	false	sufficient binding region:1553-1962|flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15350	ensembl:ENSG00000196532	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-6502329	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:hist1h3c_human_gene(display_short)|psi-mi:ENSG00000196532(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	De et al. (2012)	pubmed:21725362|imex:IM-18630	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6502349|imex:IM-18630-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	-	-	-	-	figure legend:4c|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/01/18	2014/10/16	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	-	intact-crc:C710C5F0CB2334A1	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O15350	ensembl:ENSG00000124635	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-6502331	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:hist1h2bj_human_gene(display_short)|psi-mi:ENSG00000124635(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	De et al. (2012)	pubmed:21725362|imex:IM-18630	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6502353|imex:IM-18630-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	-	-	-	-	figure legend:4c|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/01/18	2014/10/16	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	-	intact-crc:C09036AFE8E8CC92	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O15350	ensembl:ENSG00000198518	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-6502333	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:hist1h4e_human_gene(display_short)|psi-mi:ENSG00000198518(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	De et al. (2012)	pubmed:21725362|imex:IM-18630	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6502357|imex:IM-18630-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	-	-	-	-	figure legend:4c|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/01/18	2014/10/16	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	-	intact-crc:FB7CC978133668F9	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O15350	ensembl:ENSG00000197459	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-6502335	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:hist1h2bh_human_gene(display_short)|psi-mi:ENSG00000197459(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	De et al. (2012)	pubmed:21725362|imex:IM-18630	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1262"(I2D)	intact:EBI-6502361|imex:IM-18630-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	-	-	-	-	figure legend:4c|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/01/18	2014/10/16	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	-	intact-crc:45D9B75314E93A75	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)