#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:16761"	uniprotkb:P03004	intact:EBI-1188073	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0049"(filter binding)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553440|imex:IM-18696-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	go:"GO:0005524"(ATP binding)	-	-	figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	-	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:50CF35394940ABD8	false	32p radiolabel:?-?	mutation decreasing interaction:422-422|mutation decreasing interaction:423-423	1	1	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
chebi:"CHEBI:15422"	uniprotkb:P03004	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0049"(filter binding)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553435|imex:IM-18696-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	go:"GO:0005524"(ATP binding)	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.0x10^-8(molar)	2013/02/28	2014/10/16	-	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:AF39AE9E5E0E15E8	false	32p radiolabel:?-?	-	1	1	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
chebi:"CHEBI:15422"	uniprotkb:P03004	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0880"(atpase assay)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553536|imex:IM-18696-8	-	-	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	go:"GO:0006200"(obsolete ATP catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0005524"(ATP binding)	-	-	figure legend:Fig. 2d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	-	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:C58873E17C5B7D8F	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P03004	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0880"(atpase assay)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553550|imex:IM-18696-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATP hydrolysis activity)	-	-	figure legend:Fig. 2c, e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	-	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:DF25DDD99831D398	false	32p radiolabel:?-?	mutation decreasing interaction:423-423|mutation disrupting interaction:422-422|mutation disrupting interaction:422-422	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P69931	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:"MI:0880"(atpase assay)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553550|imex:IM-18696-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATP hydrolysis activity)	-	-	figure legend:Fig. 2c, e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	-	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	intact-crc:DF25DDD99831D398	false	32p radiolabel:?-?	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A988	uniprotkb:P69931	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6558672|imex:IM-18696-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	-	caution:This sequence has been withdrawn from Uniprot.	-	figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	intact-crc:44D6FD6C2CCC66B3|rigid:MP0+ueUvbIAk4nO8VSxixb9SGW4	false	-	his tag:c-c	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P69931	uniprotkb:P03004	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553731|imex:IM-18696-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	-	-	-	figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:F69316721FB0DA11|rigid:QrsqAnCy6ed2qXay11FzkGrFcJM	false	his tag:c-c|mutation disrupting interaction:6-6	mutation decreasing interaction:422-422|mutation decreasing interaction:422-422|mutation decreasing interaction:423-423	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P69931	uniprotkb:P0A988	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553731|imex:IM-18696-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	-	-	caution:This sequence has been withdrawn from Uniprot.	figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	intact-crc:F69316721FB0DA11|rigid:QrsqAnCy6ed2qXay11FzkGrFcJM	false	his tag:c-c|mutation disrupting interaction:6-6	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P69931	uniprotkb:P03004	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553761|imex:IM-18696-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	-	-	-	figure legend:Fig. 4b, c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/28	2014/10/16	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:48FA1821A4130ECD|rigid:vvIcB3kZ3q8VbCdW/y8sOOLojgg	false	his tag:c-c	mutation decreasing interaction:422-422|mutation decreasing interaction:422-422|mutation decreasing interaction:423-423	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16761"	chebi:"CHEBI:15422"	intact:EBI-1188073	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553787|imex:IM-18696-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0043234"	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2013/02/28	2014/10/16	-	-	intact-crc:7FB39A8AD4B7BAF4	false	32p radiolabel:?-?	32p radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
chebi:"CHEBI:16761"	uniprotkb:P03004	intact:EBI-1188073	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:adp(display_short)|psi-mi:"CHEBI:16761"(display_long)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Keyamura et al. (2011)	pubmed:21708944|imex:IM-18696	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553787|imex:IM-18696-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0043234"	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2013/02/28	2014/10/16	-	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:7FB39A8AD4B7BAF4	false	32p radiolabel:?-?	mutation decreasing interaction:423-423|mutation decreasing interaction:422-422|mutation decreasing interaction:422-422	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)