#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9VQ91 uniprotkb:Q7PLK0 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915399|imex:IM-21057-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 - - - figure legend:Fig, 1B, 2A, 2E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 intact-crc:783224FD833B905B|rigid:A58hxmCYtIXymwqvkmrGw3uiplM false sufficient binding region:257-576 mutation disrupting interaction strength:68-68,70-70,72-72|necessary binding region:1-289 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O76922 uniprotkb:Q9VQ91 intact:EBI-98862|ensemblmetazoa:FBpp0079754|uniprotkb:A8DYZ0|uniprotkb:K7WQ34|uniprotkb:K7X543|uniprotkb:K7XHY9|uniprotkb:L0CPY1|uniprotkb:L0CQ70|uniprotkb:L0CRA0|uniprotkb:L0CRA6|uniprotkb:L0CRP1|uniprotkb:L0CRZ4|uniprotkb:L0CS00 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 psi-mi:aub_drome(display_long)|uniprotkb:aub(gene name)|psi-mi:aub(display_short)|uniprotkb:Protein sting(gene name synonym)|uniprotkb:CG6137(orf name) psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6916380|imex:IM-21057-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0000146(gene)|ensemblmetazoa:FBtr0080165(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016246"(RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|refseq:NP_476734.1|flybase:FBgn0000146|refseq:NP_001097144.1|go:"GO:0035282"(segmentation)|go:"GO:0043186"(P granule)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0046012"(positive regulation of oskar mRNA translation)|go:"GO:0046594"(maintenance of pole plasm mRNA location)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:O76922|rcsb pdb:3NTH|rcsb pdb:3NTI|rcsb pdb:7CFD ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 - - - figure legend:Fig, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/08/05 2014/10/16 rogid:dxvXt77vU7s/JVvdQ7nO+Lb7BRc7227 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 intact-crc:D5A1E012EEE3CE2E|rigid:p3zMOpVHaXXN088Cm0AnSSrT4HE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VKM1 uniprotkb:Q9VQ91 intact:EBI-3406276|ensemblmetazoa:FBpp0079755|ensemblmetazoa:FBpp0309202|uniprotkb:C0PTU6|uniprotkb:K7WKS7|uniprotkb:K7WKT2|uniprotkb:K7WQ39|uniprotkb:K7WS94|uniprotkb:K7XHZ2|uniprotkb:L0CPR8|uniprotkb:L0CPS4|uniprotkb:L0CQ04|uniprotkb:L0CR36|uniprotkb:L0CRH9|uniprotkb:L0CRI5|uniprotkb:L0CRU0|uniprotkb:O96674|uniprotkb:O96675|uniprotkb:Q6NNZ4|uniprotkb:Q6NP34 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 psi-mi:piwi_drome(display_long)|uniprotkb:piwi(gene name)|psi-mi:piwi(display_short)|uniprotkb:CG6122(orf name) psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915378|imex:IM-21057-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0004872(gene)|ensemblmetazoa:FBtr0080166(transcript)|ensemblmetazoa:FBtr0340227(transcript)|go:"GO:0000335"(negative regulation of transposition, DNA-mediated)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0007279"(pole cell formation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0010369"(chromocenter)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034584"(piRNA binding)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070725"(Yb body)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990511"(piRNA biosynthetic process)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|rcsb pdb:5YGD|rcsb pdb:5YGF|rcsb pdb:6KR6|go:"GO:0048132"(female germ-line stem cell asymmetric division)|dip:DIP-61694N|flybase:FBgn0004872|refseq:NP_001285825.1|refseq:NP_476875.1 ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 - - - figure legend:Fig, 1B, Supp. Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/08/05 2014/10/16 rogid:rciT/36xveNKYfXHDX/fTn4Ar8c7227 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 intact-crc:9853DEADF1364F28|rigid:0u/iTmdgVNc/IjmTv5CxeaH9XBg false mutation disrupting interaction strength:7-7,9-9|necessary binding region:1-257 sufficient binding region:257-576 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VQ91 uniprotkb:Q7PLK0 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6915560|imex:IM-21057-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 go:"GO:0043186"(P granule) - - figure legend:Fig, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 intact-crc:EF753E35909A0D14|rigid:A58hxmCYtIXymwqvkmrGw3uiplM false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9VQ91 uniprotkb:Q9VKM1 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-3406276|ensemblmetazoa:FBpp0079755|ensemblmetazoa:FBpp0309202|uniprotkb:C0PTU6|uniprotkb:K7WKS7|uniprotkb:K7WKT2|uniprotkb:K7WQ39|uniprotkb:K7WS94|uniprotkb:K7XHZ2|uniprotkb:L0CPR8|uniprotkb:L0CPS4|uniprotkb:L0CQ04|uniprotkb:L0CR36|uniprotkb:L0CRH9|uniprotkb:L0CRI5|uniprotkb:L0CRU0|uniprotkb:O96674|uniprotkb:O96675|uniprotkb:Q6NNZ4|uniprotkb:Q6NP34 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:piwi_drome(display_long)|uniprotkb:piwi(gene name)|psi-mi:piwi(display_short)|uniprotkb:CG6122(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6917723|imex:IM-21057-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 ensemblmetazoa:FBgn0004872(gene)|ensemblmetazoa:FBtr0080166(transcript)|ensemblmetazoa:FBtr0340227(transcript)|go:"GO:0000335"(negative regulation of transposition, DNA-mediated)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0007279"(pole cell formation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0010369"(chromocenter)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034584"(piRNA binding)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070725"(Yb body)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990511"(piRNA biosynthetic process)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|rcsb pdb:5YGD|rcsb pdb:5YGF|rcsb pdb:6KR6|go:"GO:0048132"(female germ-line stem cell asymmetric division)|dip:DIP-61694N|flybase:FBgn0004872|refseq:NP_001285825.1|refseq:NP_476875.1 - - - figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:rciT/36xveNKYfXHDX/fTn4Ar8c7227 intact-crc:6209159515B1EEB6|rigid:pJRiTWtzcAMIBZpxOn7ReLquMBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQ91 uniprotkb:O76922 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-98862|ensemblmetazoa:FBpp0079754|uniprotkb:A8DYZ0|uniprotkb:K7WQ34|uniprotkb:K7X543|uniprotkb:K7XHY9|uniprotkb:L0CPY1|uniprotkb:L0CQ70|uniprotkb:L0CRA0|uniprotkb:L0CRA6|uniprotkb:L0CRP1|uniprotkb:L0CRZ4|uniprotkb:L0CS00 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:aub_drome(display_long)|uniprotkb:aub(gene name)|psi-mi:aub(display_short)|uniprotkb:Protein sting(gene name synonym)|uniprotkb:CG6137(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6917723|imex:IM-21057-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 ensemblmetazoa:FBgn0000146(gene)|ensemblmetazoa:FBtr0080165(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016246"(RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|refseq:NP_476734.1|flybase:FBgn0000146|refseq:NP_001097144.1|go:"GO:0035282"(segmentation)|go:"GO:0043186"(P granule)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0046012"(positive regulation of oskar mRNA translation)|go:"GO:0046594"(maintenance of pole plasm mRNA location)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:O76922|rcsb pdb:3NTH|rcsb pdb:3NTI|rcsb pdb:7CFD - - - figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:dxvXt77vU7s/JVvdQ7nO+Lb7BRc7227 intact-crc:6209159515B1EEB6|rigid:pJRiTWtzcAMIBZpxOn7ReLquMBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQ91 uniprotkb:Q7PLK0 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6917723|imex:IM-21057-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 - - - figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 intact-crc:6209159515B1EEB6|rigid:pJRiTWtzcAMIBZpxOn7ReLquMBw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O76922 uniprotkb:Q9VQ91 intact:EBI-98862|ensemblmetazoa:FBpp0079754|uniprotkb:A8DYZ0|uniprotkb:K7WQ34|uniprotkb:K7X543|uniprotkb:K7XHY9|uniprotkb:L0CPY1|uniprotkb:L0CQ70|uniprotkb:L0CRA0|uniprotkb:L0CRA6|uniprotkb:L0CRP1|uniprotkb:L0CRZ4|uniprotkb:L0CS00 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 psi-mi:aub_drome(display_long)|uniprotkb:aub(gene name)|psi-mi:aub(display_short)|uniprotkb:Protein sting(gene name synonym)|uniprotkb:CG6137(orf name) psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6918644|imex:IM-21057-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0000146(gene)|ensemblmetazoa:FBtr0080165(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016246"(RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030717"(oocyte karyosome formation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|refseq:NP_476734.1|flybase:FBgn0000146|refseq:NP_001097144.1|go:"GO:0035282"(segmentation)|go:"GO:0043186"(P granule)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0046011"(regulation of oskar mRNA translation)|go:"GO:0046012"(positive regulation of oskar mRNA translation)|go:"GO:0046594"(maintenance of pole plasm mRNA location)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0048477"(oogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:O76922|rcsb pdb:3NTH|rcsb pdb:3NTI|rcsb pdb:7CFD ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 go:"GO:0043186"(P granule) - - figure legend:Suppl fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-egg_chamber)|taxid:7227(drome egg chamber) - 2013/08/05 2014/10/16 rogid:dxvXt77vU7s/JVvdQ7nO+Lb7BRc7227 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 intact-crc:95D52B2FFE19B586|rigid:p3zMOpVHaXXN088Cm0AnSSrT4HE false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q7PLK0 uniprotkb:Q7KN62 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915579|imex:IM-21057-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 - - - figure legend:Fig, 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 intact-crc:0922784267A13B76|rigid:O8lQ1zPieQnQbU7SmSd8UCNx5IA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7PLK0 uniprotkb:M9PF20 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 intact:EBI-6915566|ensemblmetazoa:FBpp0304887 psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:m9pf20_drome(display_long)|uniprotkb:tral(gene name)|psi-mi:tral(display_short)|uniprotkb:CG10686(orf name)|uniprotkb:"BEST:GH08269"(gene name synonym)|uniprotkb:DmLSm15(gene name synonym)|uniprotkb:Dmel\CG10686(gene name synonym)|uniprotkb:LSm15(gene name synonym)|uniprotkb:Lsm15(gene name synonym)|uniprotkb:Scd6p(gene name synonym)|uniprotkb:TRAL(gene name synonym)|uniprotkb:Tral(gene name synonym)|uniprotkb:"anon-EST:Posey139"(gene name synonym)|uniprotkb:anon-WO0172774.89(gene name synonym)|uniprotkb:anon-WO02059370.24(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Dmel_CG10686(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915579|imex:IM-21057-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 ensemblmetazoa:FBgn0041775(gene)|ensemblmetazoa:FBtr0332641(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043186"(P granule)|go:"GO:0045169"(fusome)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|flybase:FBgn0041775|refseq:NP_001261775.1 - - - figure legend:Fig, 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 rogid:JLr+MDTyJ47q5z1i4OMP/fV/GgQ7227 intact-crc:0922784267A13B76|rigid:O8lQ1zPieQnQbU7SmSd8UCNx5IA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQ91 uniprotkb:Q7PLK0 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915415|imex:IM-21057-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 - - - figure legend:Fig, 1C, 2F|comment:Interaction not observed in dPRMT5-/- cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 intact-crc:9F491F3F8BE32922|rigid:A58hxmCYtIXymwqvkmrGw3uiplM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7PLK0 uniprotkb:Q9VQ91 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915442|imex:IM-21057-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 - - - figure legend:Fig, 1D|comment:The interaction between PAPI and AGO3 is RNA independent.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 intact-crc:9AEFC19C7E7D7993|rigid:A58hxmCYtIXymwqvkmrGw3uiplM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQ91 uniprotkb:Q7KN62 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-224053|uniprotkb:A8DY85|uniprotkb:A8DY86|uniprotkb:O76279|uniprotkb:Q9U463|intact:EBI-868187|ensemblmetazoa:FBpp0087479 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:tera_drome(display_long)|uniprotkb:TER94(gene name)|psi-mi:TER94(display_short)|uniprotkb:VCP(gene name synonym)|uniprotkb:Valosin-containing protein homolog(gene name synonym)|uniprotkb:CG2331(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915572|imex:IM-21057-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 refseq:NP_001097249.1|refseq:NP_001097250.1|refseq:NP_477369.1|flybase:FBgn0286784|dip:DIP-52184N|ensemblmetazoa:FBgn0286784(gene)|ensemblmetazoa:FBtr0088391(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007279"(pole cell formation)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044754"(autolysosome)|go:"GO:0045169"(fusome)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048477"(oogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|rcsb pdb:4RV0|reactome:R-DME-110320|reactome:R-DME-3371511|reactome:R-DME-382556|reactome:R-DME-532668|reactome:R-DME-5358346|reactome:R-DME-5689896|reactome:R-DME-6798695|reactome:R-DME-8876725|reactome:R-DME-9013407 - - - figure legend:Fig, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:fnh+1rCUacMwGJRyZV82HEjkNCA7227 intact-crc:01920295FF1A7318|rigid:ZoYovdyAkPyu6HFuhFaRkzvyHQU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQ91 uniprotkb:P23128 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-300281|ensemblmetazoa:FBpp0079565|uniprotkb:Q8IPC9|uniprotkb:Q961D2|uniprotkb:Q9VL17 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:ddx6_drome(display_long)|uniprotkb:me31B(gene name)|psi-mi:me31B(display_short)|uniprotkb:CG4916(orf name)|uniprotkb:Maternal expression at 31B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915572|imex:IM-21057-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 ensemblmetazoa:FBgn0004419(gene)|ensemblmetazoa:FBtr0079975(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007279"(pole cell formation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043186"(P granule)|go:"GO:0046959"(habituation)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0060148"(positive regulation of posttranscriptional gene silencing)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0071683"(sensory dendrite)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:0098794"(postsynapse)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:6S8R|reactome:R-DME-430039|refseq:NP_523533.2|refseq:NP_723539.1|flybase:FBgn0004419 - - - figure legend:Fig, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:qN9bybi82EScbklfgAdPnCZV/G07227 intact-crc:01920295FF1A7318|rigid:ZoYovdyAkPyu6HFuhFaRkzvyHQU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQ91 uniprotkb:M9PF20 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-6915566|ensemblmetazoa:FBpp0304887 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:m9pf20_drome(display_long)|uniprotkb:tral(gene name)|psi-mi:tral(display_short)|uniprotkb:CG10686(orf name)|uniprotkb:"BEST:GH08269"(gene name synonym)|uniprotkb:DmLSm15(gene name synonym)|uniprotkb:Dmel\CG10686(gene name synonym)|uniprotkb:LSm15(gene name synonym)|uniprotkb:Lsm15(gene name synonym)|uniprotkb:Scd6p(gene name synonym)|uniprotkb:TRAL(gene name synonym)|uniprotkb:Tral(gene name synonym)|uniprotkb:"anon-EST:Posey139"(gene name synonym)|uniprotkb:anon-WO0172774.89(gene name synonym)|uniprotkb:anon-WO02059370.24(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Dmel_CG10686(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915572|imex:IM-21057-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 ensemblmetazoa:FBgn0041775(gene)|ensemblmetazoa:FBtr0332641(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043186"(P granule)|go:"GO:0045169"(fusome)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|flybase:FBgn0041775|refseq:NP_001261775.1 - - - figure legend:Fig, 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:JLr+MDTyJ47q5z1i4OMP/fV/GgQ7227 intact-crc:01920295FF1A7318|rigid:ZoYovdyAkPyu6HFuhFaRkzvyHQU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VKM1 uniprotkb:Q9VQ91 intact:EBI-3406276|ensemblmetazoa:FBpp0079755|ensemblmetazoa:FBpp0309202|uniprotkb:C0PTU6|uniprotkb:K7WKS7|uniprotkb:K7WKT2|uniprotkb:K7WQ39|uniprotkb:K7WS94|uniprotkb:K7XHZ2|uniprotkb:L0CPR8|uniprotkb:L0CPS4|uniprotkb:L0CQ04|uniprotkb:L0CR36|uniprotkb:L0CRH9|uniprotkb:L0CRI5|uniprotkb:L0CRU0|uniprotkb:O96674|uniprotkb:O96675|uniprotkb:Q6NNZ4|uniprotkb:Q6NP34 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 psi-mi:piwi_drome(display_long)|uniprotkb:piwi(gene name)|psi-mi:piwi(display_short)|uniprotkb:CG6122(orf name) psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:"MI:0018"(two hybrid) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6915303|imex:IM-21057-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0004872(gene)|ensemblmetazoa:FBtr0080166(transcript)|ensemblmetazoa:FBtr0340227(transcript)|go:"GO:0000335"(negative regulation of transposition, DNA-mediated)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0007279"(pole cell formation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0010369"(chromocenter)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034584"(piRNA binding)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070725"(Yb body)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990511"(piRNA biosynthetic process)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|rcsb pdb:5YGD|rcsb pdb:5YGF|rcsb pdb:6KR6|go:"GO:0048132"(female germ-line stem cell asymmetric division)|dip:DIP-61694N|flybase:FBgn0004872|refseq:NP_001285825.1|refseq:NP_476875.1 ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 - - - figure legend:Fig, 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/08/05 2014/10/16 rogid:rciT/36xveNKYfXHDX/fTn4Ar8c7227 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 intact-crc:3205C8E2DD65B224|rigid:0u/iTmdgVNc/IjmTv5CxeaH9XBg false sufficient binding region:1-491 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9VQ91 uniprotkb:Q9VTZ0 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-126687|uniprotkb:Q8T0T8|ensemblmetazoa:FBpp0075691|ensemblmetazoa:FBpp0304881 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:q9vtz0_drome(display_long)|uniprotkb:tral(gene name)|psi-mi:tral(display_short)|uniprotkb:"BEST:GH08269"(gene name synonym)|uniprotkb:TRAL(gene name synonym)|uniprotkb:Tral(gene name synonym)|uniprotkb:"anon-EST:Posey139"(gene name synonym)|uniprotkb:anon-WO0172774.89(gene name synonym)|uniprotkb:anon-WO02059370.24(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Dmel_CG10686(orf name)|uniprotkb:DmLSm15(gene name synonym)|uniprotkb:Dmel\CG10686(gene name synonym)|uniprotkb:LSm15(gene name synonym)|uniprotkb:Lsm15(gene name synonym)|uniprotkb:Scd6p(gene name synonym)|uniprotkb:CG10686(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-8786658|imex:IM-21057-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 ensemblmetazoa:FBgn0041775(gene)|ensemblmetazoa:FBtr0075959(transcript)|ensemblmetazoa:FBtr0332635(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043186"(P granule)|go:"GO:0045169"(fusome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR025768|rcsb pdb:2VXE|interpro:IPR025761|refseq:NP_648585.3|flybase:FBgn0041775|refseq:NP_001261769.1 go:"GO:0043186"(P granule) - - figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:UNa1GhfQYzq9jsDGbatJmeJ8Nfg7227 intact-crc:FFBE53F874C98472|rigid:4X/Hn+ltbNryg5tlx8LRacTXIq0 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9VQ91 uniprotkb:Q7PLK0 intact:EBI-6915287|ensemblmetazoa:FBpp0077508|ensemblmetazoa:FBpp0077509|ensemblmetazoa:FBpp0077510|ensemblmetazoa:FBpp0077511 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 psi-mi:tdrkh_drome(display_long)|uniprotkb:papi(gene name)|psi-mi:papi(display_short)|uniprotkb:Partner of PIWIs protein(gene name synonym)|uniprotkb:Tdrd2(gene name synonym)|uniprotkb:CG7082(orf name) psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6915545|imex:IM-21057-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0031401(gene)|ensemblmetazoa:FBtr0077836(transcript)|ensemblmetazoa:FBtr0077837(transcript)|ensemblmetazoa:FBtr0077838(transcript)|ensemblmetazoa:FBtr0077839(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043186"(P granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070895"(negative regulation of transposon integration)|go:"GO:1903829"(positive regulation of protein localization)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|rcsb pdb:5YGB|rcsb pdb:5YGC|rcsb pdb:5YGD|rcsb pdb:5YGF|refseq:NP_608657.1|refseq:NP_722773.1|refseq:NP_722774.1|refseq:NP_722775.1|flybase:FBgn0031401 refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 go:"GO:0043186"(P granule) - - figure legend:Fig, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:fEM/FhkTXBcBij8hGLFYhmnwCrM7227 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 intact-crc:D4D1D2B62FBAFE3B|rigid:A58hxmCYtIXymwqvkmrGw3uiplM false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q7PLK0 uniprotkb:Q9VTZ0 intact:EBI-3431981|uniprotkb:A4GND8|uniprotkb:A4GUJ7|uniprotkb:A7YFW6|uniprotkb:B6IDV1|uniprotkb:B7FNN2|uniprotkb:K7WKR9|uniprotkb:K7XHY4|ensemblmetazoa:FBpp0289158|ensemblmetazoa:FBpp0289159|ensemblmetazoa:FBpp0289160 intact:EBI-126687|uniprotkb:Q8T0T8|ensemblmetazoa:FBpp0075691|ensemblmetazoa:FBpp0304881 psi-mi:ago3_drome(display_long)|uniprotkb:AGO3(gene name)|psi-mi:AGO3(display_short)|uniprotkb:CG40300(orf name) psi-mi:q9vtz0_drome(display_long)|uniprotkb:tral(gene name)|psi-mi:tral(display_short)|uniprotkb:"BEST:GH08269"(gene name synonym)|uniprotkb:TRAL(gene name synonym)|uniprotkb:Tral(gene name synonym)|uniprotkb:"anon-EST:Posey139"(gene name synonym)|uniprotkb:anon-WO0172774.89(gene name synonym)|uniprotkb:anon-WO02059370.24(gene name synonym)|uniprotkb:p67(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Dmel_CG10686(orf name)|uniprotkb:DmLSm15(gene name synonym)|uniprotkb:Dmel\CG10686(gene name synonym)|uniprotkb:LSm15(gene name synonym)|uniprotkb:Lsm15(gene name synonym)|uniprotkb:Scd6p(gene name synonym)|uniprotkb:CG10686(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Liu et al. (2011) pubmed:21447556|imex:IM-21057 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-8786653|imex:IM-21057-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036627.2|refseq:NP_001036628.2|refseq:NP_001036629.2|flybase:FBgn0250816|ensemblmetazoa:FBgn0250816(gene)|ensemblmetazoa:FBtr0299880(transcript)|ensemblmetazoa:FBtr0299881(transcript)|ensemblmetazoa:FBtr0299882(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034584"(piRNA binding)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7PLK0|rcsb pdb:7CFC|refseq:NP_001163498.1 ensemblmetazoa:FBgn0041775(gene)|ensemblmetazoa:FBtr0075959(transcript)|ensemblmetazoa:FBtr0332635(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043186"(P granule)|go:"GO:0045169"(fusome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR025768|rcsb pdb:2VXE|interpro:IPR025761|refseq:NP_648585.3|flybase:FBgn0041775|refseq:NP_001261769.1 go:"GO:0043186"(P granule) - - figure legend:Fig, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-ovary)|taxid:7227(Drosophila melanogaster ovary) - 2013/08/05 2014/10/16 rogid:LkGeU/cR7ptgRUCi24KjcZ2YG3Y7227 rogid:UNa1GhfQYzq9jsDGbatJmeJ8Nfg7227 intact-crc:4D770B0FA2705C07|rigid:NXje3lOhQ+zAh1VELXIt2n1uaL0 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)