#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0ACF0	uniprotkb:P03004	intact:EBI-547648|uniprotkb:P02342|uniprotkb:Q2M8T7|ensemblbacteria:BAE77319|ensemblbacteria:AAC76974	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	psi-mi:dbha_ecoli(display_long)|uniprotkb:hupA(gene name)|psi-mi:hupA(display_short)|uniprotkb:b4000(locus name)|uniprotkb:NS2(gene name synonym)|uniprotkb:HU-2(gene name synonym)|uniprotkb:JW3964(locus name)	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Chodavarapu et al. (2011)	pubmed:21288885|imex:IM-18693	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553000|imex:IM-18693-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418428.1|refseq:WP_001044513.1|dip:DIP-35892N|ensemblbacteria:BAE77319(gene)|ensemblbacteria:BAE77319(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016020"(membrane)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990178"(HU-DNA complex)|interpro:IPR000119(Histone-like bacterial DNA-binding protein)|interpro:IPR010992(IHF-like DNA-binding)|interpro:IPR020816|rcsb pdb:1MUL|rcsb pdb:2O97|rcsb pdb:4YEW|rcsb pdb:4YEX|rcsb pdb:4YEY|rcsb pdb:4YF0|rcsb pdb:4YFH|rcsb pdb:4YFT|rcsb pdb:6O6K|rcsb pdb:6O8Q|rcsb pdb:6OAJ|ensemblbacteria:AAC76974(transcript)|ensemblbacteria:b4000(gene)	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)	-	-	comment:"DnaA delta1-129aa significantly reduces binding to HU (dbha/bdhb) and DnaA delta220-294aa slightly reduces binding to HU (dbha/bdhb)."|figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/27	2014/10/16	rogid:RkQox7Fz5aPOfB/qm/Ffg0mwXK483333	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	intact-crc:E8B1BAF7876BC416|rigid:mfeSM2m0xAtDhd6vaz/nPdEdjlQ	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P03004	uniprotkb:P60422	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	intact:EBI-543515|uniprotkb:P02387|uniprotkb:Q2M6Y2|ensemblbacteria:AAC76342|ensemblbacteria:BAE77974	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:rl2_ecoli(display_long)|uniprotkb:rplB(gene name)|psi-mi:rplB(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym)|uniprotkb:JW3279(locus name)|uniprotkb:b3317(locus name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Chodavarapu et al. (2011)	pubmed:21288885|imex:IM-18693	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6552976|imex:IM-18693-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	rcsb pdb:3JCE|rcsb pdb:3JCJ|rcsb pdb:3JCN|rcsb pdb:487D|rcsb pdb:4CSU|rcsb pdb:4U1U|rcsb pdb:4U1V|rcsb pdb:4U20|rcsb pdb:4U24|rcsb pdb:4U25|rcsb pdb:4U26|rcsb pdb:4U27|rcsb pdb:4UY8|rcsb pdb:4V47|rcsb pdb:4V48|rcsb pdb:4V4H|rcsb pdb:4V4Q|rcsb pdb:4V4V|rcsb pdb:4V4W|rcsb pdb:4V50|rcsb pdb:4V52|rcsb pdb:4V53|rcsb pdb:4V54|rcsb pdb:4V55|rcsb pdb:4V56|rcsb pdb:4V57|rcsb pdb:4V5B|rcsb pdb:4V5H|rcsb pdb:4V5Y|rcsb pdb:4V64|rcsb pdb:4V65|rcsb pdb:4V66|rcsb pdb:4V69|rcsb pdb:4V6C|rcsb pdb:4V6D|rcsb pdb:4V6E|rcsb pdb:4V6K|rcsb pdb:4V6L|rcsb pdb:4V6M|rcsb pdb:4V6N|rcsb pdb:4V6O|rcsb pdb:4V6P|rcsb pdb:4V6Q|rcsb pdb:4V6R|rcsb pdb:4V6S|rcsb pdb:4V6T|rcsb pdb:4V6V|rcsb pdb:4V6Y|rcsb pdb:4V6Z|rcsb pdb:4V70|rcsb pdb:4V71|rcsb pdb:4V72|ensemblbacteria:AAC76342(transcript)|ensemblbacteria:b3317(gene)|ensemblbacteria:BAE77974(gene)|ensemblbacteria:BAE77974(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5WE4|rcsb pdb:5WE6|rcsb pdb:5WFK|rcsb pdb:6BU8|rcsb pdb:6BY1|rcsb pdb:6C4H|rcsb pdb:6ENF|rcsb pdb:6ENJ|rcsb pdb:6ENU|rcsb pdb:6GBZ|rcsb pdb:6GC0|rcsb pdb:6GC4|rcsb pdb:6GC6|rcsb pdb:6GC8|rcsb pdb:6GWT|rcsb pdb:6GXM|rcsb pdb:6GXN|rcsb pdb:6GXO|rcsb pdb:6GXP|rcsb pdb:6H4N|rcsb pdb:6H58|rcsb pdb:6HRM|rcsb pdb:6I0Y|rcsb pdb:6I7V|rcsb pdb:6O9J|rcsb pdb:6O9K|rcsb pdb:6OFX|rcsb pdb:6OG7|rcsb pdb:6OGF|rcsb pdb:5AKA|rcsb pdb:5GAD|rcsb pdb:5GAE|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5H5U|rcsb pdb:5IQR|rcsb pdb:5IT8|rcsb pdb:5J5B|rcsb pdb:5J7L|rcsb pdb:5J88|rcsb pdb:5J8A|rcsb pdb:5J91|rcsb pdb:5JC9|rcsb pdb:5JTE|rcsb pdb:5JU8|rcsb pdb:5KCR|rcsb pdb:5KCS|rcsb pdb:5KPS|rcsb pdb:5KPV|rcsb pdb:5KPW|rcsb pdb:5KPX|rcsb pdb:5L3P|rcsb pdb:5LZA|rcsb pdb:5LZB|rcsb pdb:5LZC|rcsb pdb:5LZD|rcsb pdb:5LZE|rcsb pdb:5LZF|rcsb pdb:5MDV|rcsb pdb:5MDW|rcsb pdb:5MDY|rcsb pdb:5MDZ|rcsb pdb:5MGP|rcsb pdb:5NCO|rcsb pdb:5NP6|rcsb pdb:5NWY|rcsb pdb:5O2R|rcsb pdb:5U4I|rcsb pdb:5U9F|rcsb pdb:5U9G|rcsb pdb:5UYK|rcsb pdb:5UYL|rcsb pdb:5UYM|rcsb pdb:5UYN|rcsb pdb:5UYP|rcsb pdb:5UYQ|rcsb pdb:5WDT|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR005880(Ribosomal protein L2, bacterial-type)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|rcsb pdb:2J28|rcsb pdb:2RDO|rcsb pdb:3BBX|rcsb pdb:3J5L|rcsb pdb:3J7Z|rcsb pdb:3J8G|rcsb pdb:3J9Y|rcsb pdb:3J9Z|rcsb pdb:3JA1|rcsb pdb:3JBU|rcsb pdb:3JBV|rcsb pdb:3JCD|rcsb pdb:4V73|rcsb pdb:4V74|rcsb pdb:4V75|rcsb pdb:4V76|rcsb pdb:4V77|rcsb pdb:4V78|rcsb pdb:4V79|rcsb pdb:4V7A|rcsb pdb:4V7B|rcsb pdb:4V7C|rcsb pdb:4V7D|rcsb pdb:4V7I|rcsb pdb:4V7S|rcsb pdb:4V7T|rcsb pdb:4V7U|rcsb pdb:4V7V|rcsb pdb:4V85|rcsb pdb:4V89|rcsb pdb:4V9C|rcsb pdb:4V9D|rcsb pdb:4V9O|rcsb pdb:4V9P|rcsb pdb:4WF1|rcsb pdb:4WOI|rcsb pdb:4WWW|rcsb pdb:4YBB|rcsb pdb:5ADY|rcsb pdb:5AFI|rcsb pdb:6QDW|rcsb pdb:6QUL|rcsb pdb:6S0K|rcsb pdb:6SZS|rcsb pdb:6TBV|rcsb pdb:6TC3|rcsb pdb:6VU3|rcsb pdb:6VWL|rcsb pdb:6VWM|rcsb pdb:6VWN|rcsb pdb:6VYQ|rcsb pdb:6VYR|rcsb pdb:6VYS|rcsb pdb:6VYT|rcsb pdb:6VYU|rcsb pdb:6VYW|rcsb pdb:6VYX|rcsb pdb:6VYY|rcsb pdb:6VYZ|rcsb pdb:6VZ2|rcsb pdb:6VZ3|rcsb pdb:6VZ5|rcsb pdb:6VZ7|rcsb pdb:6VZJ|rcsb pdb:6WD0|rcsb pdb:6WD1|rcsb pdb:6WD2|rcsb pdb:6WD3|rcsb pdb:6WD4|rcsb pdb:6WD5|rcsb pdb:6WD6|rcsb pdb:6WD7|rcsb pdb:6WD8|rcsb pdb:6WD9|rcsb pdb:6WDA|rcsb pdb:6WDB|rcsb pdb:6WDC|rcsb pdb:6WDD|rcsb pdb:6WDE|rcsb pdb:6WDF|rcsb pdb:6WDG|rcsb pdb:6WDH|rcsb pdb:6WDI|rcsb pdb:6WDJ|rcsb pdb:6WDK|rcsb pdb:6WDL|rcsb pdb:6WDM|rcsb pdb:6WNT|rcsb pdb:6WNV|rcsb pdb:6WNW|rcsb pdb:6WYV|rcsb pdb:6X6T|rcsb pdb:6X7F|rcsb pdb:6OGG|rcsb pdb:6OGI|rcsb pdb:6OM6|rcsb pdb:6ORE|rcsb pdb:6ORL|rcsb pdb:6OST|rcsb pdb:6OT3|rcsb pdb:6OUO|rcsb pdb:6PC5|rcsb pdb:6PC6|rcsb pdb:6PC7|rcsb pdb:6PC8|rcsb pdb:6PCH|rcsb pdb:6PCQ|rcsb pdb:6PCR|rcsb pdb:6PCS|rcsb pdb:6PCT|rcsb pdb:6Q98|rcsb pdb:6Q9A|refseq:NP_417776.1|rcsb pdb:6X7K|rcsb pdb:6X9Q|rcsb pdb:6XDQ|rcsb pdb:6XDR|rcsb pdb:6XGF|rcsb pdb:6XII|rcsb pdb:6XIJ|rcsb pdb:6XZ7|rcsb pdb:6XZA|rcsb pdb:6XZB|rcsb pdb:6Y69|rcsb pdb:6YS3|rcsb pdb:6YSR|rcsb pdb:6YSS|rcsb pdb:6YST|rcsb pdb:6YSU|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:7B5K|rcsb pdb:7BL2|rcsb pdb:7BL3|rcsb pdb:7BL4|rcsb pdb:7BL5|rcsb pdb:7BL6|rcsb pdb:7BV8|rcsb pdb:7D6Z|rcsb pdb:7D80|rcsb pdb:7JSS|rcsb pdb:7JSW|rcsb pdb:7JSZ|rcsb pdb:7JT1|rcsb pdb:7JT2|rcsb pdb:7JT3|rcsb pdb:7K00|refseq:WP_000301864.1|dip:DIP-35747N	go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)	-	-	comment:DnaA delta1-129aa significantly reduces binding to L2 and DnaA delta220-294aa reduces binding to L2 by a lesser degree.|figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/27	2014/10/16	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	rogid:zBVODxTU/DGhZWyFaDT5VwWQOEI83333	intact-crc:2DEEAFDDCF5FD915|rigid:his0ZpwFGUEUGa4IMBbNp5isrwI	false	necessary binding region:1-129	sufficient binding region:214-273	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P03004	uniprotkb:P60422	intact:EBI-548951|uniprotkb:P78122|uniprotkb:Q2M814|ensemblbacteria:AAC76725|ensemblbacteria:BAE77592	intact:EBI-543515|uniprotkb:P02387|uniprotkb:Q2M6Y2|ensemblbacteria:AAC76342|ensemblbacteria:BAE77974	psi-mi:dnaa_ecoli(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:b3702(locus name)|uniprotkb:JW3679(locus name)	psi-mi:rl2_ecoli(display_long)|uniprotkb:rplB(gene name)|psi-mi:rplB(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym)|uniprotkb:JW3279(locus name)|uniprotkb:b3317(locus name)	psi-mi:"MI:0071"(molecular sieving)	Chodavarapu et al. (2011)	pubmed:21288885|imex:IM-18693	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553028|imex:IM-18693-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418157.1|refseq:WP_000059111.1|dip:DIP-9455N|ensemblbacteria:AAC76725(transcript)|ensemblbacteria:b3702(gene)|ensemblbacteria:BAE77592(gene)|ensemblbacteria:BAE77592(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010921(Trp repressor/replication initiator)|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR018312|interpro:IPR020591|interpro:IPR024633|interpro:IPR027417|interpro:IPR038454|rcsb pdb:1J1V|rcsb pdb:2E0G|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)	rcsb pdb:3JCE|rcsb pdb:3JCJ|rcsb pdb:3JCN|rcsb pdb:487D|rcsb pdb:4CSU|rcsb pdb:4U1U|rcsb pdb:4U1V|rcsb pdb:4U20|rcsb pdb:4U24|rcsb pdb:4U25|rcsb pdb:4U26|rcsb pdb:4U27|rcsb pdb:4UY8|rcsb pdb:4V47|rcsb pdb:4V48|rcsb pdb:4V4H|rcsb pdb:4V4Q|rcsb pdb:4V4V|rcsb pdb:4V4W|rcsb pdb:4V50|rcsb pdb:4V52|rcsb pdb:4V53|rcsb pdb:4V54|rcsb pdb:4V55|rcsb pdb:4V56|rcsb pdb:4V57|rcsb pdb:4V5B|rcsb pdb:4V5H|rcsb pdb:4V5Y|rcsb pdb:4V64|rcsb pdb:4V65|rcsb pdb:4V66|rcsb pdb:4V69|rcsb pdb:4V6C|rcsb pdb:4V6D|rcsb pdb:4V6E|rcsb pdb:4V6K|rcsb pdb:4V6L|rcsb pdb:4V6M|rcsb pdb:4V6N|rcsb pdb:4V6O|rcsb pdb:4V6P|rcsb pdb:4V6Q|rcsb pdb:4V6R|rcsb pdb:4V6S|rcsb pdb:4V6T|rcsb pdb:4V6V|rcsb pdb:4V6Y|rcsb pdb:4V6Z|rcsb pdb:4V70|rcsb pdb:4V71|rcsb pdb:4V72|ensemblbacteria:AAC76342(transcript)|ensemblbacteria:b3317(gene)|ensemblbacteria:BAE77974(gene)|ensemblbacteria:BAE77974(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5WE4|rcsb pdb:5WE6|rcsb pdb:5WFK|rcsb pdb:6BU8|rcsb pdb:6BY1|rcsb pdb:6C4H|rcsb pdb:6ENF|rcsb pdb:6ENJ|rcsb pdb:6ENU|rcsb pdb:6GBZ|rcsb pdb:6GC0|rcsb pdb:6GC4|rcsb pdb:6GC6|rcsb pdb:6GC8|rcsb pdb:6GWT|rcsb pdb:6GXM|rcsb pdb:6GXN|rcsb pdb:6GXO|rcsb pdb:6GXP|rcsb pdb:6H4N|rcsb pdb:6H58|rcsb pdb:6HRM|rcsb pdb:6I0Y|rcsb pdb:6I7V|rcsb pdb:6O9J|rcsb pdb:6O9K|rcsb pdb:6OFX|rcsb pdb:6OG7|rcsb pdb:6OGF|rcsb pdb:5AKA|rcsb pdb:5GAD|rcsb pdb:5GAE|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5H5U|rcsb pdb:5IQR|rcsb pdb:5IT8|rcsb pdb:5J5B|rcsb pdb:5J7L|rcsb pdb:5J88|rcsb pdb:5J8A|rcsb pdb:5J91|rcsb pdb:5JC9|rcsb pdb:5JTE|rcsb pdb:5JU8|rcsb pdb:5KCR|rcsb pdb:5KCS|rcsb pdb:5KPS|rcsb pdb:5KPV|rcsb pdb:5KPW|rcsb pdb:5KPX|rcsb pdb:5L3P|rcsb pdb:5LZA|rcsb pdb:5LZB|rcsb pdb:5LZC|rcsb pdb:5LZD|rcsb pdb:5LZE|rcsb pdb:5LZF|rcsb pdb:5MDV|rcsb pdb:5MDW|rcsb pdb:5MDY|rcsb pdb:5MDZ|rcsb pdb:5MGP|rcsb pdb:5NCO|rcsb pdb:5NP6|rcsb pdb:5NWY|rcsb pdb:5O2R|rcsb pdb:5U4I|rcsb pdb:5U9F|rcsb pdb:5U9G|rcsb pdb:5UYK|rcsb pdb:5UYL|rcsb pdb:5UYM|rcsb pdb:5UYN|rcsb pdb:5UYP|rcsb pdb:5UYQ|rcsb pdb:5WDT|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR005880(Ribosomal protein L2, bacterial-type)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|rcsb pdb:2J28|rcsb pdb:2RDO|rcsb pdb:3BBX|rcsb pdb:3J5L|rcsb pdb:3J7Z|rcsb pdb:3J8G|rcsb pdb:3J9Y|rcsb pdb:3J9Z|rcsb pdb:3JA1|rcsb pdb:3JBU|rcsb pdb:3JBV|rcsb pdb:3JCD|rcsb pdb:4V73|rcsb pdb:4V74|rcsb pdb:4V75|rcsb pdb:4V76|rcsb pdb:4V77|rcsb pdb:4V78|rcsb pdb:4V79|rcsb pdb:4V7A|rcsb pdb:4V7B|rcsb pdb:4V7C|rcsb pdb:4V7D|rcsb pdb:4V7I|rcsb pdb:4V7S|rcsb pdb:4V7T|rcsb pdb:4V7U|rcsb pdb:4V7V|rcsb pdb:4V85|rcsb pdb:4V89|rcsb pdb:4V9C|rcsb pdb:4V9D|rcsb pdb:4V9O|rcsb pdb:4V9P|rcsb pdb:4WF1|rcsb pdb:4WOI|rcsb pdb:4WWW|rcsb pdb:4YBB|rcsb pdb:5ADY|rcsb pdb:5AFI|rcsb pdb:6QDW|rcsb pdb:6QUL|rcsb pdb:6S0K|rcsb pdb:6SZS|rcsb pdb:6TBV|rcsb pdb:6TC3|rcsb pdb:6VU3|rcsb pdb:6VWL|rcsb pdb:6VWM|rcsb pdb:6VWN|rcsb pdb:6VYQ|rcsb pdb:6VYR|rcsb pdb:6VYS|rcsb pdb:6VYT|rcsb pdb:6VYU|rcsb pdb:6VYW|rcsb pdb:6VYX|rcsb pdb:6VYY|rcsb pdb:6VYZ|rcsb pdb:6VZ2|rcsb pdb:6VZ3|rcsb pdb:6VZ5|rcsb pdb:6VZ7|rcsb pdb:6VZJ|rcsb pdb:6WD0|rcsb pdb:6WD1|rcsb pdb:6WD2|rcsb pdb:6WD3|rcsb pdb:6WD4|rcsb pdb:6WD5|rcsb pdb:6WD6|rcsb pdb:6WD7|rcsb pdb:6WD8|rcsb pdb:6WD9|rcsb pdb:6WDA|rcsb pdb:6WDB|rcsb pdb:6WDC|rcsb pdb:6WDD|rcsb pdb:6WDE|rcsb pdb:6WDF|rcsb pdb:6WDG|rcsb pdb:6WDH|rcsb pdb:6WDI|rcsb pdb:6WDJ|rcsb pdb:6WDK|rcsb pdb:6WDL|rcsb pdb:6WDM|rcsb pdb:6WNT|rcsb pdb:6WNV|rcsb pdb:6WNW|rcsb pdb:6WYV|rcsb pdb:6X6T|rcsb pdb:6X7F|rcsb pdb:6OGG|rcsb pdb:6OGI|rcsb pdb:6OM6|rcsb pdb:6ORE|rcsb pdb:6ORL|rcsb pdb:6OST|rcsb pdb:6OT3|rcsb pdb:6OUO|rcsb pdb:6PC5|rcsb pdb:6PC6|rcsb pdb:6PC7|rcsb pdb:6PC8|rcsb pdb:6PCH|rcsb pdb:6PCQ|rcsb pdb:6PCR|rcsb pdb:6PCS|rcsb pdb:6PCT|rcsb pdb:6Q98|rcsb pdb:6Q9A|refseq:NP_417776.1|rcsb pdb:6X7K|rcsb pdb:6X9Q|rcsb pdb:6XDQ|rcsb pdb:6XDR|rcsb pdb:6XGF|rcsb pdb:6XII|rcsb pdb:6XIJ|rcsb pdb:6XZ7|rcsb pdb:6XZA|rcsb pdb:6XZB|rcsb pdb:6Y69|rcsb pdb:6YS3|rcsb pdb:6YSR|rcsb pdb:6YSS|rcsb pdb:6YST|rcsb pdb:6YSU|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:7B5K|rcsb pdb:7BL2|rcsb pdb:7BL3|rcsb pdb:7BL4|rcsb pdb:7BL5|rcsb pdb:7BL6|rcsb pdb:7BV8|rcsb pdb:7D6Z|rcsb pdb:7D80|rcsb pdb:7JSS|rcsb pdb:7JSW|rcsb pdb:7JSZ|rcsb pdb:7JT1|rcsb pdb:7JT2|rcsb pdb:7JT3|rcsb pdb:7K00|refseq:WP_000301864.1|dip:DIP-35747N	go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)	-	-	figure legend:Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/27	2014/10/16	rogid:p07cXpfl7bzSh/kImTD/+Zr0Ma883333	rogid:zBVODxTU/DGhZWyFaDT5VwWQOEI83333	intact-crc:35351BE9D1077D26|rigid:his0ZpwFGUEUGa4IMBbNp5isrwI	false	his tag:n-n	sufficient binding region:1-214	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P60422	uniprotkb:P0ACB0	intact:EBI-543515|uniprotkb:P02387|uniprotkb:Q2M6Y2|ensemblbacteria:AAC76342|ensemblbacteria:BAE77974	intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054	psi-mi:rl2_ecoli(display_long)|uniprotkb:rplB(gene name)|psi-mi:rplB(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym)|uniprotkb:JW3279(locus name)|uniprotkb:b3317(locus name)	psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name)	psi-mi:"MI:0071"(molecular sieving)	Chodavarapu et al. (2011)	pubmed:21288885|imex:IM-18693	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6553052|imex:IM-18693-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3JCE|rcsb pdb:3JCJ|rcsb pdb:3JCN|rcsb pdb:487D|rcsb pdb:4CSU|rcsb pdb:4U1U|rcsb pdb:4U1V|rcsb pdb:4U20|rcsb pdb:4U24|rcsb pdb:4U25|rcsb pdb:4U26|rcsb pdb:4U27|rcsb pdb:4UY8|rcsb pdb:4V47|rcsb pdb:4V48|rcsb pdb:4V4H|rcsb pdb:4V4Q|rcsb pdb:4V4V|rcsb pdb:4V4W|rcsb pdb:4V50|rcsb pdb:4V52|rcsb pdb:4V53|rcsb pdb:4V54|rcsb pdb:4V55|rcsb pdb:4V56|rcsb pdb:4V57|rcsb pdb:4V5B|rcsb pdb:4V5H|rcsb pdb:4V5Y|rcsb pdb:4V64|rcsb pdb:4V65|rcsb pdb:4V66|rcsb pdb:4V69|rcsb pdb:4V6C|rcsb pdb:4V6D|rcsb pdb:4V6E|rcsb pdb:4V6K|rcsb pdb:4V6L|rcsb pdb:4V6M|rcsb pdb:4V6N|rcsb pdb:4V6O|rcsb pdb:4V6P|rcsb pdb:4V6Q|rcsb pdb:4V6R|rcsb pdb:4V6S|rcsb pdb:4V6T|rcsb pdb:4V6V|rcsb pdb:4V6Y|rcsb pdb:4V6Z|rcsb pdb:4V70|rcsb pdb:4V71|rcsb pdb:4V72|ensemblbacteria:AAC76342(transcript)|ensemblbacteria:b3317(gene)|ensemblbacteria:BAE77974(gene)|ensemblbacteria:BAE77974(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5WE4|rcsb pdb:5WE6|rcsb pdb:5WFK|rcsb pdb:6BU8|rcsb pdb:6BY1|rcsb pdb:6C4H|rcsb pdb:6ENF|rcsb pdb:6ENJ|rcsb pdb:6ENU|rcsb pdb:6GBZ|rcsb pdb:6GC0|rcsb pdb:6GC4|rcsb pdb:6GC6|rcsb pdb:6GC8|rcsb pdb:6GWT|rcsb pdb:6GXM|rcsb pdb:6GXN|rcsb pdb:6GXO|rcsb pdb:6GXP|rcsb pdb:6H4N|rcsb pdb:6H58|rcsb pdb:6HRM|rcsb pdb:6I0Y|rcsb pdb:6I7V|rcsb pdb:6O9J|rcsb pdb:6O9K|rcsb pdb:6OFX|rcsb pdb:6OG7|rcsb pdb:6OGF|rcsb pdb:5AKA|rcsb pdb:5GAD|rcsb pdb:5GAE|rcsb pdb:5GAF|rcsb pdb:5GAG|rcsb pdb:5GAH|rcsb pdb:5H5U|rcsb pdb:5IQR|rcsb pdb:5IT8|rcsb pdb:5J5B|rcsb pdb:5J7L|rcsb pdb:5J88|rcsb pdb:5J8A|rcsb pdb:5J91|rcsb pdb:5JC9|rcsb pdb:5JTE|rcsb pdb:5JU8|rcsb pdb:5KCR|rcsb pdb:5KCS|rcsb pdb:5KPS|rcsb pdb:5KPV|rcsb pdb:5KPW|rcsb pdb:5KPX|rcsb pdb:5L3P|rcsb pdb:5LZA|rcsb pdb:5LZB|rcsb pdb:5LZC|rcsb pdb:5LZD|rcsb pdb:5LZE|rcsb pdb:5LZF|rcsb pdb:5MDV|rcsb pdb:5MDW|rcsb pdb:5MDY|rcsb pdb:5MDZ|rcsb pdb:5MGP|rcsb pdb:5NCO|rcsb pdb:5NP6|rcsb pdb:5NWY|rcsb pdb:5O2R|rcsb pdb:5U4I|rcsb pdb:5U9F|rcsb pdb:5U9G|rcsb pdb:5UYK|rcsb pdb:5UYL|rcsb pdb:5UYM|rcsb pdb:5UYN|rcsb pdb:5UYP|rcsb pdb:5UYQ|rcsb pdb:5WDT|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016740"(transferase activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR005880(Ribosomal protein L2, bacterial-type)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|rcsb pdb:2J28|rcsb pdb:2RDO|rcsb pdb:3BBX|rcsb pdb:3J5L|rcsb pdb:3J7Z|rcsb pdb:3J8G|rcsb pdb:3J9Y|rcsb pdb:3J9Z|rcsb pdb:3JA1|rcsb pdb:3JBU|rcsb pdb:3JBV|rcsb pdb:3JCD|rcsb pdb:4V73|rcsb pdb:4V74|rcsb pdb:4V75|rcsb pdb:4V76|rcsb pdb:4V77|rcsb pdb:4V78|rcsb pdb:4V79|rcsb pdb:4V7A|rcsb pdb:4V7B|rcsb pdb:4V7C|rcsb pdb:4V7D|rcsb pdb:4V7I|rcsb pdb:4V7S|rcsb pdb:4V7T|rcsb pdb:4V7U|rcsb pdb:4V7V|rcsb pdb:4V85|rcsb pdb:4V89|rcsb pdb:4V9C|rcsb pdb:4V9D|rcsb pdb:4V9O|rcsb pdb:4V9P|rcsb pdb:4WF1|rcsb pdb:4WOI|rcsb pdb:4WWW|rcsb pdb:4YBB|rcsb pdb:5ADY|rcsb pdb:5AFI|rcsb pdb:6QDW|rcsb pdb:6QUL|rcsb pdb:6S0K|rcsb pdb:6SZS|rcsb pdb:6TBV|rcsb pdb:6TC3|rcsb pdb:6VU3|rcsb pdb:6VWL|rcsb pdb:6VWM|rcsb pdb:6VWN|rcsb pdb:6VYQ|rcsb pdb:6VYR|rcsb pdb:6VYS|rcsb pdb:6VYT|rcsb pdb:6VYU|rcsb pdb:6VYW|rcsb pdb:6VYX|rcsb pdb:6VYY|rcsb pdb:6VYZ|rcsb pdb:6VZ2|rcsb pdb:6VZ3|rcsb pdb:6VZ5|rcsb pdb:6VZ7|rcsb pdb:6VZJ|rcsb pdb:6WD0|rcsb pdb:6WD1|rcsb pdb:6WD2|rcsb pdb:6WD3|rcsb pdb:6WD4|rcsb pdb:6WD5|rcsb pdb:6WD6|rcsb pdb:6WD7|rcsb pdb:6WD8|rcsb pdb:6WD9|rcsb pdb:6WDA|rcsb pdb:6WDB|rcsb pdb:6WDC|rcsb pdb:6WDD|rcsb pdb:6WDE|rcsb pdb:6WDF|rcsb pdb:6WDG|rcsb pdb:6WDH|rcsb pdb:6WDI|rcsb pdb:6WDJ|rcsb pdb:6WDK|rcsb pdb:6WDL|rcsb pdb:6WDM|rcsb pdb:6WNT|rcsb pdb:6WNV|rcsb pdb:6WNW|rcsb pdb:6WYV|rcsb pdb:6X6T|rcsb pdb:6X7F|rcsb pdb:6OGG|rcsb pdb:6OGI|rcsb pdb:6OM6|rcsb pdb:6ORE|rcsb pdb:6ORL|rcsb pdb:6OST|rcsb pdb:6OT3|rcsb pdb:6OUO|rcsb pdb:6PC5|rcsb pdb:6PC6|rcsb pdb:6PC7|rcsb pdb:6PC8|rcsb pdb:6PCH|rcsb pdb:6PCQ|rcsb pdb:6PCR|rcsb pdb:6PCS|rcsb pdb:6PCT|rcsb pdb:6Q98|rcsb pdb:6Q9A|refseq:NP_417776.1|rcsb pdb:6X7K|rcsb pdb:6X9Q|rcsb pdb:6XDQ|rcsb pdb:6XDR|rcsb pdb:6XGF|rcsb pdb:6XII|rcsb pdb:6XIJ|rcsb pdb:6XZ7|rcsb pdb:6XZA|rcsb pdb:6XZB|rcsb pdb:6Y69|rcsb pdb:6YS3|rcsb pdb:6YSR|rcsb pdb:6YSS|rcsb pdb:6YST|rcsb pdb:6YSU|rcsb pdb:6ZTJ|rcsb pdb:6ZTL|rcsb pdb:6ZTM|rcsb pdb:6ZTN|rcsb pdb:6ZTO|rcsb pdb:6ZTP|rcsb pdb:6ZU1|rcsb pdb:7B5K|rcsb pdb:7BL2|rcsb pdb:7BL3|rcsb pdb:7BL4|rcsb pdb:7BL5|rcsb pdb:7BL6|rcsb pdb:7BV8|rcsb pdb:7D6Z|rcsb pdb:7D80|rcsb pdb:7JSS|rcsb pdb:7JSW|rcsb pdb:7JSZ|rcsb pdb:7JT1|rcsb pdb:7JT2|rcsb pdb:7JT3|rcsb pdb:7K00|refseq:WP_000301864.1|dip:DIP-35747N	refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM	-	-	-	figure legend:Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/27	2014/10/16	rogid:zBVODxTU/DGhZWyFaDT5VwWQOEI83333	rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333	intact-crc:00F8A0FD298B59C9|rigid:z4xyzqwWylIMihnPaVOzeKDbx2I	false	sufficient binding region:1-214	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)