#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-6623343 uniprotkb:P02767 - intact:EBI-6675014|ensembl:ENSRNOP00000022113|uniprotkb:Q547K9 psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:tthy_rat(display_long)|uniprotkb:Ttr(gene name)|psi-mi:Ttr(display_short)|uniprotkb:Tt(gene name synonym)|uniprotkb:Prealbumin(gene name synonym)|uniprotkb:TBPA(gene name synonym) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692575|imex:IM-26566-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSRNOG00000016275(gene)|ensembl:ENSRNOT00000022113(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042403"(thyroid hormone metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR030178|interpro:IPR036817|mint:P02767|rcsb pdb:1GKE|rcsb pdb:1IE4|rcsb pdb:1KGI|rcsb pdb:1KGJ|rcsb pdb:1RVS|rcsb pdb:2M5K|rcsb pdb:2M5M|rcsb pdb:3ZPK|reactome:R-RNO-2453902|reactome:R-RNO-3000171|reactome:R-RNO-6798695|reactome:R-RNO-975634|refseq:XP_006254519.1|refseq:NP_036813.2|rgd:3916 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2014/10/16 - rogid:36h5MG2Ta1EfNQcgB1d8+GneH4810116 intact-crc:AD37F73566F9AF37 false 125i radiolabel:?-? - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 uniprotkb:P50390 - intact:EBI-6623357|ensembl:ENSSSCP00060036610|uniprotkb:Q2IA93 psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:tthy_pig(display_long)|uniprotkb:TTR(gene name)|psi-mi:TTR(display_short)|uniprotkb:Prealbumin(gene name synonym) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692557|imex:IM-26566-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSSSCG00060061967(gene)|ensembl:ENSSSCT00060084543(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0036094"(small molecule binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR036817|reactome:R-SSC-2453902|reactome:R-SSC-6798695|reactome:R-SSC-975634|interpro:IPR030178|refseq:NP_999377.1 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2014/10/16 - rogid:p5zA4OiZ1XSVhlY2OCbZiv4BNXE9823 intact-crc:2B89D6B3D0320B6B false 125i radiolabel:?-? - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 uniprotkb:P27731 - intact:EBI-6622511 psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:tthy_chick(display_long)|uniprotkb:TTR(gene name)|psi-mi:TTR(display_short)|uniprotkb:Prealbumin(gene name synonym)|uniprotkb:TBPA(gene name synonym) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692529|imex:IM-26566-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0001555"(oocyte growth)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036094"(small molecule binding)|go:"GO:0042562"(hormone binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060417"(yolk)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR030178|refseq:NP_990666.1|interpro:IPR023418|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023419|rcsb pdb:1TFP|interpro:IPR036817 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2019/01/30 - rogid:wG0MwmIpjkKk3XQmc9Zkag5RNwc9031 intact-crc:CE86E0DCE658321C false 125i radiolabel:?-? - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 intact:EBI-6623343 - - psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692537|imex:IM-26566-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2019/01/30 - - intact-crc:0BB18029618C2562 false - 125i radiolabel:?-? - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 uniprotkb:P27731 - intact:EBI-6622511 psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:tthy_chick(display_long)|uniprotkb:TTR(gene name)|psi-mi:TTR(display_short)|uniprotkb:Prealbumin(gene name synonym)|uniprotkb:TBPA(gene name synonym) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692537|imex:IM-26566-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0001555"(oocyte growth)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036094"(small molecule binding)|go:"GO:0042562"(hormone binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060417"(yolk)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR030178|refseq:NP_990666.1|interpro:IPR023418|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023419|rcsb pdb:1TFP|interpro:IPR036817 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2019/01/30 - rogid:wG0MwmIpjkKk3XQmc9Zkag5RNwc9031 intact-crc:0BB18029618C2562 false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 intact:EBI-6623343 - - psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692565|imex:IM-26566-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2014/10/16 - - intact-crc:E4D2C055937E7B20 false 125i radiolabel:?-? - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 uniprotkb:P02767 - intact:EBI-6675014|ensembl:ENSRNOP00000022113|uniprotkb:Q547K9 psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:tthy_rat(display_long)|uniprotkb:Ttr(gene name)|psi-mi:Ttr(display_short)|uniprotkb:Tt(gene name synonym)|uniprotkb:Prealbumin(gene name synonym)|uniprotkb:TBPA(gene name synonym) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692565|imex:IM-26566-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSRNOG00000016275(gene)|ensembl:ENSRNOT00000022113(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042403"(thyroid hormone metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR030178|interpro:IPR036817|mint:P02767|rcsb pdb:1GKE|rcsb pdb:1IE4|rcsb pdb:1KGI|rcsb pdb:1KGJ|rcsb pdb:1RVS|rcsb pdb:2M5K|rcsb pdb:2M5M|rcsb pdb:3ZPK|reactome:R-RNO-2453902|reactome:R-RNO-3000171|reactome:R-RNO-6798695|reactome:R-RNO-975634|refseq:XP_006254519.1|refseq:NP_036813.2|rgd:3916 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2014/10/16 - rogid:36h5MG2Ta1EfNQcgB1d8+GneH4810116 intact-crc:E4D2C055937E7B20 false 125i radiolabel:?-? - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 intact:EBI-6623343 - - psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692547|imex:IM-26566-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2019/01/30 - - intact-crc:EEBEB64657E61C15 false - 125i radiolabel:?-? - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) intact:EBI-6623343 uniprotkb:P50390 - intact:EBI-6623357|ensembl:ENSSSCP00060036610|uniprotkb:Q2IA93 psi-mi:"chebi:230446"(display_short)|psi-mi:EBI-6623343(display_long) psi-mi:tthy_pig(display_long)|uniprotkb:TTR(gene name)|psi-mi:TTR(display_short)|uniprotkb:Prealbumin(gene name synonym) psi-mi:"MI:0405"(competition binding) Yamauchi et al. (2011) pubmed:21147258|imex:IM-26566 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6692547|imex:IM-26566-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSSSCG00060061967(gene)|ensembl:ENSSSCT00060084543(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0036094"(small molecule binding)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR036817|reactome:R-SSC-2453902|reactome:R-SSC-6798695|reactome:R-SSC-975634|interpro:IPR030178|refseq:NP_999377.1 - - - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/16 2019/01/30 - rogid:p5zA4OiZ1XSVhlY2OCbZiv4BNXE9823 intact-crc:EEBEB64657E61C15 false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining)