#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12003	uniprotkb:F1PUT6	intact:EBI-1039563|uniprotkb:Q91024|ensembl:ENSGALP00000008131	intact:EBI-6620952|ensembl:ENSCAFP00000015046	psi-mi:vinc_chick(display_long)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)|uniprotkb:VINC1(gene name synonym)|uniprotkb:Metavinculin(gene name synonym)	psi-mi:f1put6_canlf(display_long)|uniprotkb:PXN(gene name)|psi-mi:PXN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	le et al. (2010)	imex:IM-18864|pubmed:20584916	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6620950|imex:IM-18864-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015143689.1|refseq:NP_990772.1|ensembl:ENSGALG00000005079(gene)|ensembl:ENSGALT00000008145(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|rcsb pdb:1QKR|rcsb pdb:1ST6|rcsb pdb:1T01|rcsb pdb:1U6H|rcsb pdb:1XWJ|rcsb pdb:1ZVZ|rcsb pdb:1ZW2|rcsb pdb:1ZW3|rcsb pdb:2GDC|rcsb pdb:3JBI|rcsb pdb:3ZDL|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:6FQ4|rcsb pdb:6NR7|reactome:R-GGA-114608|reactome:R-GGA-445355|reactome:R-GGA-5674135|reactome:R-GGA-6798695|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P12003|dip:DIP-35191N	ensembl:ENSCAFG00000010241(gene)|ensembl:ENSCAFT00000016266(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001904(Paxillin)|reactome:R-CFA-180292|reactome:R-CFA-4420097|reactome:R-CFA-445355|reactome:R-CFA-446343|reactome:R-CFA-446388|reactome:R-CFA-8849471	-	-	-	figure legend:Fig 3C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2013/04/19	2020/01/08	rogid:94z6CivjYryFIKVVE4dRTbssflA9031	rogid:t6G70KC6189G+9Tka3WnCi4x3/U9615	intact-crc:48CC0D3A56A6717E|rigid:Y2YKL1tJMJL5CFBw0fumUHhajV4	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12003	uniprotkb:B6V8E6	intact:EBI-1039563|uniprotkb:Q91024|ensembl:ENSGALP00000008131	intact:EBI-1549187	psi-mi:vinc_chick(display_long)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)|uniprotkb:VINC1(gene name synonym)|uniprotkb:Metavinculin(gene name synonym)	psi-mi:ctnb1_canlf(display_long)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:Beta-catenin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	le et al. (2010)	imex:IM-18864|pubmed:20584916	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6620950|imex:IM-18864-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015143689.1|refseq:NP_990772.1|ensembl:ENSGALG00000005079(gene)|ensembl:ENSGALT00000008145(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|rcsb pdb:1QKR|rcsb pdb:1ST6|rcsb pdb:1T01|rcsb pdb:1U6H|rcsb pdb:1XWJ|rcsb pdb:1ZVZ|rcsb pdb:1ZW2|rcsb pdb:1ZW3|rcsb pdb:2GDC|rcsb pdb:3JBI|rcsb pdb:3ZDL|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:6FQ4|rcsb pdb:6NR7|reactome:R-GGA-114608|reactome:R-GGA-445355|reactome:R-GGA-5674135|reactome:R-GGA-6798695|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P12003|dip:DIP-35191N	refseq:NP_001131124.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|refseq:XP_013961954.1|refseq:XP_013961955.1|go:"GO:0000922"(spindle pole)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045202"(synapse)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000008"(regulation of protein localization to cell surface)	-	-	-	figure legend:Fig 3C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2013/04/19	2020/01/08	rogid:94z6CivjYryFIKVVE4dRTbssflA9031	rogid:29IyntaqY7McjU1KoKWKAJNCt809615	intact-crc:48CC0D3A56A6717E|rigid:Y2YKL1tJMJL5CFBw0fumUHhajV4	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P12003	uniprotkb:Q95LE0	intact:EBI-1039563|uniprotkb:Q91024|ensembl:ENSGALP00000008131	intact:EBI-1549266|intact:EBI-2643534	psi-mi:vinc_chick(display_long)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)|uniprotkb:VINC1(gene name synonym)|uniprotkb:Metavinculin(gene name synonym)	psi-mi:q95le0_canlf(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	le et al. (2010)	imex:IM-18864|pubmed:20584916	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6620950|imex:IM-18864-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015143689.1|refseq:NP_990772.1|ensembl:ENSGALG00000005079(gene)|ensembl:ENSGALT00000008145(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|rcsb pdb:1QKR|rcsb pdb:1ST6|rcsb pdb:1T01|rcsb pdb:1U6H|rcsb pdb:1XWJ|rcsb pdb:1ZVZ|rcsb pdb:1ZW2|rcsb pdb:1ZW3|rcsb pdb:2GDC|rcsb pdb:3JBI|rcsb pdb:3ZDL|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:6FQ4|rcsb pdb:6NR7|reactome:R-GGA-114608|reactome:R-GGA-445355|reactome:R-GGA-5674135|reactome:R-GGA-6798695|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P12003|dip:DIP-35191N	interpro:IPR015919(Cadherin-like)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR039808|interpro:IPR030049|mint:Q95LE0|go:"GO:0005509"(calcium ion binding)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045176"(apical protein localization)|go:"GO:0051234"(establishment of localization)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098609"(cell-cell adhesion)	-	-	-	figure legend:Fig 3C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2013/04/19	2020/01/08	rogid:94z6CivjYryFIKVVE4dRTbssflA9031	rogid:OzarZALd0VlDjhuRhKJnzFpw2VE9615	intact-crc:48CC0D3A56A6717E|rigid:Y2YKL1tJMJL5CFBw0fumUHhajV4	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09803	uniprotkb:B6V8E6	intact:EBI-984420|uniprotkb:Q61377	intact:EBI-1549187	psi-mi:cadh1_mouse(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:ARC-1(gene name synonym)|uniprotkb:Cdh1(gene name)|psi-mi:Cdh1(display_short)	psi-mi:ctnb1_canlf(display_long)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:Beta-catenin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	le et al. (2010)	imex:IM-18864|pubmed:20584916	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6620980|imex:IM-18864-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0007566"(embryo implantation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019538"(protein metabolic process)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035847"(uterine epithelium development)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0090102"(cochlea development)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043296"(apical junction complex)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|go:"GO:0043679"(axon terminus)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060693"(regulation of branching involved in salivary gland morphogenesis)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|rcsb pdb:1EDH|rcsb pdb:1FF5|rcsb pdb:1I7W|rcsb pdb:1I7X|rcsb pdb:1Q1P|rcsb pdb:1SUH|rcsb pdb:2OMW|rcsb pdb:2QVF|rcsb pdb:3IFQ|rcsb pdb:3LNE|interpro:IPR015919(Cadherin-like)|rcsb pdb:3LNF|rcsb pdb:3LNG|rcsb pdb:3LNH|rcsb pdb:3LNI|rcsb pdb:3Q2L|rcsb pdb:3Q2N|rcsb pdb:3Q2V|rcsb pdb:3QRB|rcsb pdb:4QD2|rcsb pdb:7AR4|reactome:R-MMU-1474228|reactome:R-MMU-216083|reactome:R-MMU-351906|reactome:R-MMU-418990|reactome:R-MMU-5626467|refseq:NP_033994.1|dip:DIP-29635N|mint:P09803	refseq:NP_001131124.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|refseq:XP_013961954.1|refseq:XP_013961955.1|go:"GO:0000922"(spindle pole)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045202"(synapse)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000008"(regulation of protein localization to cell surface)	-	-	-	figure legend:Fig 3C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2013/04/19	2020/01/08	rogid:VC5bbvNrxRzOFvwFCr/+CS2cSG410090	rogid:29IyntaqY7McjU1KoKWKAJNCt809615	intact-crc:4DCE45A1DF390422|rigid:z4LIFe6hGdrKwa/giwZ+f8JAQp4	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09803	uniprotkb:J9P4F3	intact:EBI-984420|uniprotkb:Q61377	intact:EBI-6620982|ensembl:ENSCAFP00000040432	psi-mi:cadh1_mouse(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:ARC-1(gene name synonym)|uniprotkb:Cdh1(gene name)|psi-mi:Cdh1(display_short)	psi-mi:j9p4f3_canlf(display_long)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)|uniprotkb:Vinculin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	le et al. (2010)	imex:IM-18864|pubmed:20584916	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6620980|imex:IM-18864-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001701"(in utero embryonic development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0007566"(embryo implantation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0019538"(protein metabolic process)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033561"(regulation of water loss via skin)|go:"GO:0034332"(adherens junction organization)|go:"GO:0035847"(uterine epithelium development)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0090102"(cochlea development)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043296"(apical junction complex)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|go:"GO:0043679"(axon terminus)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060693"(regulation of branching involved in salivary gland morphogenesis)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|rcsb pdb:1EDH|rcsb pdb:1FF5|rcsb pdb:1I7W|rcsb pdb:1I7X|rcsb pdb:1Q1P|rcsb pdb:1SUH|rcsb pdb:2OMW|rcsb pdb:2QVF|rcsb pdb:3IFQ|rcsb pdb:3LNE|interpro:IPR015919(Cadherin-like)|rcsb pdb:3LNF|rcsb pdb:3LNG|rcsb pdb:3LNH|rcsb pdb:3LNI|rcsb pdb:3Q2L|rcsb pdb:3Q2N|rcsb pdb:3Q2V|rcsb pdb:3QRB|rcsb pdb:4QD2|rcsb pdb:7AR4|reactome:R-MMU-1474228|reactome:R-MMU-216083|reactome:R-MMU-351906|reactome:R-MMU-418990|reactome:R-MMU-5626467|refseq:NP_033994.1|dip:DIP-29635N|mint:P09803	ensembl:ENSCAFG00000015254(gene)|ensembl:ENSCAFT00000050185(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0042383"(sarcolemma)|go:"GO:0051015"(actin filament binding)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723	-	-	-	figure legend:Fig 3C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2013/04/19	2020/01/08	rogid:VC5bbvNrxRzOFvwFCr/+CS2cSG410090	rogid:f+Ok1AlKLNEDcT5NbTZiYOn3xJM9615	intact-crc:4DCE45A1DF390422|rigid:z4LIFe6hGdrKwa/giwZ+f8JAQp4	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)