#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6863959|imex:IM-20903-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 6a|variable_condition:0.2 NaCl|variable_condition_2:70 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:26E26CEFDDC62571	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P17888	-	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864025|imex:IM-20903-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 5a, Table 2|variable_condition_2:20 nt|variable_condition:0.2 M|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	intact-crc:05370B5DC8EAEDFD	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AGE0	uniprotkb:P17888	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6863586|imex:IM-20903-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	-	-	-	kinetic_conditions:pH 7.5, 10% glycerol, 25C, or  pH 7.0, 25% glycerol, 25C|figure legend:Fig.s 3, 4, Table 1, 2|variable_condition:"0.02 or 0.2 M (interaction doesn't change)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	intact-crc:C881E27B9546E62C|rigid:7HB8UU9xF4oik9yzcjvaSS3ICxg	false	mutation disrupting interaction:177-177|mutation:169-169|sufficient binding region:170-178	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P28905	-	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864087|imex:IM-20903-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	kinetic_conditions:pH 7.0, 25% glycerol, 25C, or  pH 8.1, 25C|figure legend:Fig. 6b, 6c, Table 2|variable_condition:0.02 M|variable_condition_2:70 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:B52902FCC4AA0C96	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864087|imex:IM-20903-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C, or  pH 8.1, 25C|figure legend:Fig. 6b, 6c, Table 2|variable_condition:0.02 M|variable_condition_2:70 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:B52902FCC4AA0C96	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P17888	-	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6863497|imex:IM-20903-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Table 2|variable_condition_2:70 nt|variable_condition:0.2 M|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	intact-crc:4E2B8EB1095187E9	false	-	-	1	3	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AGE0	uniprotkb:P28905	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6863985|imex:IM-20903-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 6b, Table 2|variable_condition:0.2 M|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:68E15F8D222911AB|rigid:NfLDt43Dzi1f+era/3o87/dHPU4	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AGE0	intact:EBI-3953546	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	-	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864039|imex:IM-20903-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 6a|variable_condition:0.02 NaCl|variable_condition_2:70 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	-	intact-crc:F46A98A94FF60A5F	false	-	-	8	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17888	uniprotkb:P0AGE0	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864137|imex:IM-20903-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 7, Table 2|variable_condition:0.2 M|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:C69282B7BD227D4A|rigid:7HB8UU9xF4oik9yzcjvaSS3ICxg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P17888	-	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864124|imex:IM-20903-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 7, Table 2|variable_condition:0.2 M|variable_condition_2:70 nt|caution:Stoichiometry for PriA =4 in text but =3 in Table 2! The modelled stoichiometry in Fig. 8 suggests that it most likely =4.|comment:"Stoichiometry for PriA with SSB-(dT)35 was difficult to calculate but a model suggests that it is most likely =2 (see Fig.8)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	intact-crc:B1CF25E35C0554AD	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864124|imex:IM-20903-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 7, Table 2|variable_condition:0.2 M|variable_condition_2:70 nt|caution:Stoichiometry for PriA =4 in text but =3 in Table 2! The modelled stoichiometry in Fig. 8 suggests that it most likely =4.|comment:"Stoichiometry for PriA with SSB-(dT)35 was difficult to calculate but a model suggests that it is most likely =2 (see Fig.8)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:B1CF25E35C0554AD	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P17888	-	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6863576|imex:IM-20903-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 5b|variable_condition:0.2 M|variable_condition_2:20 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	intact-crc:EA215A86BE1C31C4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6863576|imex:IM-20903-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 5b|variable_condition:0.2 M|variable_condition_2:20 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:EA215A86BE1C31C4	false	-	sufficient binding region:170-178|mutation:169-169	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AGE0	intact:EBI-3953546	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	-	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864054|imex:IM-20903-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 6a|variable_condition:0.02 NaCl|variable_condition_2:70 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	-	intact-crc:55FD0874B6CE514E	false	-	-	4	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P28905	-	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864097|imex:IM-20903-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 6d, Table 2|variable_condition:0.2 M|variable_condition_2:70 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:168BF5BAE2ECD8A8	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6864097|imex:IM-20903-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	kinetic_conditions:pH 7.0, 25% glycerol, 25C|figure legend:Fig. 6d, Table 2|variable_condition:0.2 M|variable_condition_2:70 nt|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:168BF5BAE2ECD8A8	false	-	-	1	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28905	uniprotkb:P0AGE0	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Kozlov et al. (2010)	pubmed:20329707|imex:IM-20903	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6863469|imex:IM-20903-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	crc64:7FEFFC359B28AA88	-	kinetic_conditions:pH 7.5, 10% glycerol, 25C, or  pH 7.0, 25% glycerol, 25C|figure legend:Fig.s 2, 3, 4, Tables 1, 2|variable_condition:"0.02 or 0.2 M (no change in interaction)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/18	2014/10/16	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:67CE82F3CE528C91|rigid:NfLDt43Dzi1f+era/3o87/dHPU4	false	-	sufficient binding region:170-178|mutation disrupting interaction:177-177|mutation:169-169	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)