#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BT07 uniprotkb:Q7M6U3 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6674614|imex:IM-20859-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 - - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:15A7A185BC1F18BF|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BT07 uniprotkb:Q7M6U3 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6674622|imex:IM-20859-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 - - - figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:7231A327901F1C5F|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7M6U3 uniprotkb:Q7M6U3 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6674676|imex:IM-20859-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 - - - figure legend:Fig. 4b, Fig. 4c, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/05/16 2014/10/16 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:D503B25827B1A71A|rigid:+QUGtupUToBGn3b/xGNYuXGRrR8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BT07 uniprotkb:Q7M6U3 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6674685|imex:IM-20859-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 - - - figure legend:Fig. 4b, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:87B9AC337AF1AD0E|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BT07 uniprotkb:Q7M6U3 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6674691|imex:IM-20859-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 - - - figure legend:Fig. 4c, Fig. 5b, Fig. 5c, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:8BB06A1E7B1FE337|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false sufficient binding region:157-236 necessary binding region:789-815 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IWB6 uniprotkb:Q53EZ4 intact:EBI-6674697|intact:EBI-28973933|ensembl:ENSP00000240361|uniprotkb:A6NH19|uniprotkb:Q7RTP3|uniprotkb:Q8ND97|uniprotkb:Q9BXT9 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:tex14_human(display_long)|uniprotkb:TEX14(gene name)|psi-mi:TEX14(display_short)|uniprotkb:SGK307(gene name synonym)|uniprotkb:Protein kinase-like protein SgK307(gene name synonym)|uniprotkb:Sugen kinase 307(gene name synonym)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6674695|imex:IM-20859-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000240361|ensembl:ENST00000349033|ensembl:ENSP00000268910|ensembl:ENST00000389934|ensembl:ENSP00000374584|ensembl:ENSG00000121101(gene)|ensembl:ENST00000240361(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|rcsb pdb:3WUT|rcsb pdb:3WUU|go:"GO:0051306"(mitotic sister chromatid separation)|refseq:NP_001188386.1|refseq:NP_112562.3|refseq:NP_938207.2 refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N - - - figure legend:Fig. 4c, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/05/16 2014/10/16 rogid:D+snBRMsYqN6yqrtPhq+lC3L/NM9606 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:083BE22E32227CF2|rigid:WdBClI0HzTbeufwRpU/+OLmsy7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:E9Q5G3 uniprotkb:Q7M6U3 intact:EBI-2553152|uniprotkb:Q80V30|uniprotkb:Q99PT8|ensembl:ENSMUSP00000034815 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:kif23_mouse(display_long)|uniprotkb:Kif23(gene name)|psi-mi:Kif23(display_short) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6690457|imex:IM-20859-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077207.3|ensembl:ENSMUSG00000032254(gene)|ensembl:ENSMUST00000034815(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|reactome:R-MMU-2132295|reactome:R-MMU-6811434|reactome:R-MMU-68884|reactome:R-MMU-983189|go:"GO:0045171"(intercellular bridge) ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 - - - figure legend:Fig. 4b, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/05/16 2014/10/16 rogid:734bTofHqm+vN9dUUJ4YgpULwak10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:4C7AB73941C82587|rigid:6XZ46UovuTOENtT8axucDJZ4xG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WUM4 uniprotkb:Q53EZ4 intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679053|imex:IM-20859-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N - - - figure legend:Fig. 7c, Table 2|inhibition:This interaction is suppressed by overexpression of the Tex14 fragment that interacts with Cep55.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:8BB8223F68184CAA|rigid:dJTeFlG+QVQo5HRImWJqCc/hUqQ false sufficient binding region:780-868 sufficient binding region:157-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99816 uniprotkb:Q53EZ4 intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679082|imex:IM-20859-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N - - - figure legend:Fig. 7c, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:2072B22F36B21045|rigid:MqhkUeXdHGK0v3vLhhAkkO1oEh4 false sufficient binding region:146-234 sufficient binding region:157-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IWB6 uniprotkb:Q53EZ4 intact:EBI-6674697|intact:EBI-28973933|ensembl:ENSP00000240361|uniprotkb:A6NH19|uniprotkb:Q7RTP3|uniprotkb:Q8ND97|uniprotkb:Q9BXT9 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:tex14_human(display_long)|uniprotkb:TEX14(gene name)|psi-mi:TEX14(display_short)|uniprotkb:SGK307(gene name synonym)|uniprotkb:Protein kinase-like protein SgK307(gene name synonym)|uniprotkb:Sugen kinase 307(gene name synonym)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679138|imex:IM-20859-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000240361|ensembl:ENST00000349033|ensembl:ENSP00000268910|ensembl:ENST00000389934|ensembl:ENSP00000374584|ensembl:ENSG00000121101(gene)|ensembl:ENST00000240361(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|rcsb pdb:3WUT|rcsb pdb:3WUU|go:"GO:0051306"(mitotic sister chromatid separation)|refseq:NP_001188386.1|refseq:NP_112562.3|refseq:NP_938207.2 refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N - - - figure legend:Fig. 7c, Fig. 7d, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:D+snBRMsYqN6yqrtPhq+lC3L/NM9606 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:3ACB20AB60D6F0F4|rigid:WdBClI0HzTbeufwRpU/+OLmsy7A false sufficient binding region:760-819 sufficient binding region:157-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8IWB6 uniprotkb:Q53EZ4 intact:EBI-6674697|intact:EBI-28973933|ensembl:ENSP00000240361|uniprotkb:A6NH19|uniprotkb:Q7RTP3|uniprotkb:Q8ND97|uniprotkb:Q9BXT9 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:tex14_human(display_long)|uniprotkb:TEX14(gene name)|psi-mi:TEX14(display_short)|uniprotkb:SGK307(gene name synonym)|uniprotkb:Protein kinase-like protein SgK307(gene name synonym)|uniprotkb:Sugen kinase 307(gene name synonym)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679415|imex:IM-20859-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000240361|ensembl:ENST00000349033|ensembl:ENSP00000268910|ensembl:ENST00000389934|ensembl:ENSP00000374584|ensembl:ENSG00000121101(gene)|ensembl:ENST00000240361(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|rcsb pdb:3WUT|rcsb pdb:3WUU|go:"GO:0051306"(mitotic sister chromatid separation)|refseq:NP_001188386.1|refseq:NP_112562.3|refseq:NP_938207.2 refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N - - - figure legend:Fig. 7e, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:D+snBRMsYqN6yqrtPhq+lC3L/NM9606 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:5705A036A3D7A887|rigid:WdBClI0HzTbeufwRpU/+OLmsy7A false necessary binding region:795-801|sufficient binding region:760-819 sufficient binding region:157-237 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BT07 uniprotkb:Q9WU78 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-641897|uniprotkb:Q3TED2|uniprotkb:O88695|uniprotkb:O89014|uniprotkb:Q8BSL8|uniprotkb:Q8R0H5|uniprotkb:Q99LR3|uniprotkb:Q9QZN8|ensembl:ENSMUSP00000035086 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:pdc6i_mouse(display_long)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679538|imex:IM-20859-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 refseq:NP_001158149.1|refseq:NP_001158150.1|refseq:NP_035182.2|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:0043209"(myelin sheath)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q9WU78|reactome:R-MMU-5213460|reactome:R-MMU-5675482|dip:DIP-41418N - - - figure legend:Fig. 8a, Fig. 9, Table 2|inhibition:This interaction is suppressed by overexpression of the Tex14 fragment that interacts with Cep55.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 intact-crc:8098EC7455168F31|rigid:PfRPBaRD5vEFdyY+rG57ME6uJKk false sufficient binding region:157-236 sufficient binding region:781-869 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BT07 uniprotkb:Q61187 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-1202711|ensembl:ENSMUSP00000014546 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:ts101_mouse(display_long)|uniprotkb:Tsg101(gene name)|psi-mi:Tsg101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679560|imex:IM-20859-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 refseq:NP_068684.1|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|reactome:R-MMU-917729|ensembl:ENSMUSG00000014402(gene)|ensembl:ENSMUST00000014546(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0005815"(microtubule organizing center) - - - figure legend:Fig. 8b, Fig. 9, Table 2|inhibition:This interaction is suppressed by overexpression of the Tex14 fragment that interacts with Cep55.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:xaaLuoyhyn1UgchT9KTyD5FCTHg10090 intact-crc:99CB57750F397D06|rigid:AbxdRIVKHrm5UwScfqAxHfs92gI false sufficient binding region:157-236 sufficient binding region:146-235 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7M6U3 uniprotkb:Q8BT07 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679685|imex:IM-20859-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 - - - figure legend:Fig. 7f, Fig. 8c, Fig. 9, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 intact-crc:2717B7E06C0405AF|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false sufficient binding region:756-815|mutation decreasing interaction:793-793|mutation disrupting interaction:792-792|necessary binding region:791-797|mutation disrupting interaction:797-797 sufficient binding region:157-236 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7M6U3 uniprotkb:Q8BT07 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:"MI:0728"(gal4 vp16 complementation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6679721|imex:IM-20859-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/05/16 2014/10/16 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 intact-crc:B9E84EC739DDF7DC|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false sufficient binding region:756-815|necessary binding region:791-797 sufficient binding region:157-236 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BT07 uniprotkb:Q7M6U3 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6694326|imex:IM-20859-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 go:"GO:0045171"(intercellular bridge) - - figure legend:Fig. 2, Fig. 10|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:0BBB7C873CFDA7FD|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q7M6U3 uniprotkb:Q8BT07 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:"MI:0027"(cosedimentation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6694466|imex:IM-20859-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 - - - figure legend:Fig. 1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/05/16 2014/10/16 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 intact-crc:9080ED265D6CD230|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q7M6U3 uniprotkb:Q8BT07 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:"MI:0027"(cosedimentation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6694419|imex:IM-20859-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 - - - figure legend:Fig. 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/05/16 2014/10/16 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 intact-crc:3D0F3D84021C706F|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BT07 uniprotkb:E9Q5G3 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-2553152|uniprotkb:Q80V30|uniprotkb:Q99PT8|ensembl:ENSMUSP00000034815 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:kif23_mouse(display_long)|uniprotkb:Kif23(gene name)|psi-mi:Kif23(display_short) psi-mi:"MI:0027"(cosedimentation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6694432|imex:IM-20859-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 refseq:NP_077207.3|ensembl:ENSMUSG00000032254(gene)|ensembl:ENSMUST00000034815(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR032384|interpro:IPR038105|reactome:R-MMU-2132295|reactome:R-MMU-6811434|reactome:R-MMU-68884|reactome:R-MMU-983189|go:"GO:0045171"(intercellular bridge) - - - figure legend:Fig. 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:734bTofHqm+vN9dUUJ4YgpULwak10090 intact-crc:12B7DD8DDC66400F|rigid:D9EyShsQ5hbc1XZ8fvAUmxtZEyE false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8BT07 uniprotkb:Q9WVM1 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-2552104|ensembl:ENSMUSP00000023756|ensembl:ENSMUSP00000126417|uniprotkb:Q3TI41|uniprotkb:Q3TM81|uniprotkb:Q3THR5 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:rgap1_mouse(display_long)|uniprotkb:Mgcracgap(gene name synonym)|uniprotkb:Male germ cell RacGap(gene name synonym)|uniprotkb:Racgap1(gene name)|psi-mi:Racgap1(display_short) psi-mi:"MI:0027"(cosedimentation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6694432|imex:IM-20859-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 refseq:NP_001240737.1|refseq:NP_001240738.1|refseq:XP_011243948.1|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013423|reactome:R-MMU-983189|ensembl:ENSMUSG00000023015(gene)|ensembl:ENSMUST00000023756(transcript)|ensembl:ENSMUST00000171702(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008272"(sulfate transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-2132295|reactome:R-MMU-6811434|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|refseq:NP_036155.1|dip:DIP-42340N - - - figure legend:Fig. 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:Ya95AbWK+nGljvPWXuNWqGm3sqo10090 intact-crc:12B7DD8DDC66400F|rigid:D9EyShsQ5hbc1XZ8fvAUmxtZEyE false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8BT07 uniprotkb:Q7M6U3 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6694432|imex:IM-20859-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 - - - figure legend:Fig. 1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2013/05/16 2014/10/16 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 intact-crc:12B7DD8DDC66400F|rigid:D9EyShsQ5hbc1XZ8fvAUmxtZEyE false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q7M6U3 uniprotkb:Q8BT07 intact:EBI-6674575|ensembl:ENSMUSP00000054444|uniprotkb:B2KGL0|uniprotkb:Q3UT36|uniprotkb:Q5NC10|uniprotkb:Q5NC11|uniprotkb:Q8CGK1|uniprotkb:Q8CGK2|uniprotkb:Q99MV8 intact:EBI-2552328|ensembl:ENSMUSP00000093802|ensembl:ENSMUSP00000127961|ensembl:ENSMUSP00000157898|uniprotkb:Q8C2J0|uniprotkb:Q8K2I8|uniprotkb:Q9DBZ8|uniprotkb:Q8R2Y4 psi-mi:tex14_mouse(display_long)|uniprotkb:Tex14(gene name)|psi-mi:Tex14(display_short)|uniprotkb:Testis-expressed sequence 14(gene name synonym)|uniprotkb:Testis-expressed sequence 14 protein(gene name synonym) psi-mi:cep55_mouse(display_long)|uniprotkb:Cep55(gene name)|psi-mi:Cep55(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Iwamori et al. (2010) pubmed:20176808|imex:IM-20859 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6694478|imex:IM-20859-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000010342(gene)|ensembl:ENSMUST00000060835(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043063"(intercellular bridge organization)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039339|refseq:NP_001186222.1|refseq:NP_113563.2 refseq:XP_011245683.1|ensembl:ENSMUSG00000024989(gene)|ensembl:ENSMUST00000096096(transcript)|refseq:NP_001157834.1|refseq:NP_082569.1|refseq:NP_083036.2|ensembl:ENSMUST00000169673(transcript)|ensembl:ENSMUST00000236044(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|refseq:XP_006527459.1|refseq:XP_006527460.1|refseq:XP_006527461.1|refseq:XP_006527462.1|refseq:XP_006527463.1|refseq:XP_006527464.1 go:"GO:0045171"(intercellular bridge) - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-ovary)|taxid:10090(Mouse ovary) - 2013/05/16 2014/10/16 rogid:ETQECv/No8jdKuQJSMCqESuBotA10090 rogid:5th2H2Jgr4f+P5AAr8j34GnOiOo10090 intact-crc:7DCF459EEAB7960A|rigid:Zy+3UoARsYfa43fi5IqHM9Xksec false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)