#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P27958-PRO_0000037566	uniprotkb:P02675	intact:EBI-6377335	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	psi-mi:p27958-pro_0000037566(display_long)	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Ait-Goughoulte et al. (2010)	pubmed:20162731|imex:IM-26030	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6931833|imex:IM-26030-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N	-	chain-seq-start:2|chain-seq-end:191	-	figure legend:Fig. 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/08/20	2017/09/02	rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	intact-crc:5157FD620DA9B577|rigid:CguceLiBW7h5r5ibXDZyR1Lrf80	false	cYFP:?-?	nYFP:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P02675	uniprotkb:P27958-PRO_0000037566	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	intact:EBI-6377335	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:p27958-pro_0000037566(display_long)	psi-mi:"MI:0663"(confocal microscopy)	Ait-Goughoulte et al. (2010)	pubmed:20162731|imex:IM-26030	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6932428|imex:IM-26030-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N	intact:EBI-706378(chain-parent)	go:"GO:0030430"(host cell cytoplasm)	-	chain-seq-start:2|chain-seq-end:191	figure legend:Fig. 2A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2013/08/20	2017/09/02	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746	intact-crc:B4FA934264E9A285|rigid:CguceLiBW7h5r5ibXDZyR1Lrf80	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P02675	uniprotkb:P27958-PRO_0000037566	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	intact:EBI-6377335	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:p27958-pro_0000037566(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ait-Goughoulte et al. (2010)	pubmed:20162731|imex:IM-26030	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6932446|imex:IM-26030-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N	intact:EBI-706378(chain-parent)	-	-	chain-seq-start:2|chain-seq-end:191	figure legend:Fig. 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2013/08/20	2017/09/02	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746	intact-crc:58B7AE7ED8FA9B5C|rigid:CguceLiBW7h5r5ibXDZyR1Lrf80	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P27958-PRO_0000037566	uniprotkb:P02675	intact:EBI-6377335	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	psi-mi:p27958-pro_0000037566(display_long)	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ait-Goughoulte et al. (2010)	pubmed:20162731|imex:IM-26030	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6932456|imex:IM-26030-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N	-	chain-seq-start:2|chain-seq-end:191	-	figure legend:Fig. 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2013/08/20	2017/09/02	rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	intact-crc:5DDF3E12498A62C7|rigid:CguceLiBW7h5r5ibXDZyR1Lrf80	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)