#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A2A121	uniprotkb:Q63450	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-7007884|ensembl:ENSRNOP00000033456|intact:MINT-3375300|uniprotkb:Q63084	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:kcc1a_rat(display_long)|uniprotkb:Camk1(gene name)|psi-mi:Camk1(display_short)|uniprotkb:CaM kinase I(gene name synonym)|uniprotkb:CaM kinase I alpha(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006356|imex:IM-21794-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	refseq:XP_006237065.1|ensembl:ENSRNOG00000021781(gene)|ensembl:ENSRNOT00000029728(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0060143"(positive regulation of syncytium formation by plasma membrane fusion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q63450|rcsb pdb:1A06|rcsb pdb:1MXE|rcsb pdb:2L7L|reactome:R-RNO-9619229|refseq:NP_604463.1|rgd:629473	go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	function:"Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes like transcriptional regulation, hormone production, translational regulation, regulation of actin filament organization and neurite outgrowth. Involved in calcium-dependent activation of the ERK pathway (By similarity). Recognizes the substrate consensus sequence [MVLIF]-x-R-x(2)-[ST]-x(3)-[MVLIF]. Phosphorylates EIF4G3/eIF4GII. In vitro phosphorylates CREB1, ATF1, CTFR, MYL9, SYN1/synapsin I and SYNII/synapsin II"|comment:mint	figure legend:2Bi, 3B|resulting-ptm:P02687 phosres|causality statement:A2A121 decreases activity of Q63450.|comment:"The inhibitory polypeptide, zDCLK(678–810), showed weak inhibition of CaMKI."|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:7KJ2wmUk+WzmKMUkzS52jSWZ54w10116	intact-crc:63E17B6A2993ED89|rigid:tGZ/1S8oLmN/5u0Jr3E2cQfAJhA	false	his tag:c-c|glutathione s tranferase tag:n-n|sufficient binding region:678-810	his tag:c-c|t7 tag:n-n|phosphorylated residue:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	uniprotkb:P02687	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-908215|uniprotkb:Q9BGM8|uniprotkb:Q9TS63|uniprotkb:Q9TSA6	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:mbp_bovin(display_long)|uniprotkb:MBP(gene name)|psi-mi:MBP(display_short)|uniprotkb:Myelin A1 protein(gene name synonym)|uniprotkb:20 kDa microtubule-stabilizing protein(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006356|imex:IM-21794-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	mint:P02687|dip:DIP-29967N|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0071944"(cell periphery)|interpro:IPR000548(Myelin basic protein)|go:"GO:0005516"(calmodulin binding)	go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:2Bi, 3B|resulting-ptm:P02687 phosres|causality statement:A2A121 decreases activity of Q63450.|comment:"The inhibitory polypeptide, zDCLK(678–810), showed weak inhibition of CaMKI."|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:+XOfpMhDq0quW7eKyc4SY6SHvXc9913	intact-crc:63E17B6A2993ED89|rigid:tGZ/1S8oLmN/5u0Jr3E2cQfAJhA	false	his tag:c-c|glutathione s tranferase tag:n-n|sufficient binding region:678-810	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q63450	uniprotkb:P02687	intact:EBI-7007884|ensembl:ENSRNOP00000033456|intact:MINT-3375300|uniprotkb:Q63084	intact:EBI-908215|uniprotkb:Q9BGM8|uniprotkb:Q9TS63|uniprotkb:Q9TSA6	psi-mi:kcc1a_rat(display_long)|uniprotkb:Camk1(gene name)|psi-mi:Camk1(display_short)|uniprotkb:CaM kinase I(gene name synonym)|uniprotkb:CaM kinase I alpha(gene name synonym)	psi-mi:mbp_bovin(display_long)|uniprotkb:MBP(gene name)|psi-mi:MBP(display_short)|uniprotkb:Myelin A1 protein(gene name synonym)|uniprotkb:20 kDa microtubule-stabilizing protein(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9037787|imex:IM-21794-20	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006237065.1|ensembl:ENSRNOG00000021781(gene)|ensembl:ENSRNOT00000029728(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0060143"(positive regulation of syncytium formation by plasma membrane fusion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q63450|rcsb pdb:1A06|rcsb pdb:1MXE|rcsb pdb:2L7L|reactome:R-RNO-9619229|refseq:NP_604463.1|rgd:629473	mint:P02687|dip:DIP-29967N|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0071944"(cell periphery)|interpro:IPR000548(Myelin basic protein)|go:"GO:0005516"(calmodulin binding)	go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	function:"Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes like transcriptional regulation, hormone production, translational regulation, regulation of actin filament organization and neurite outgrowth. Involved in calcium-dependent activation of the ERK pathway (By similarity). Recognizes the substrate consensus sequence [MVLIF]-x-R-x(2)-[ST]-x(3)-[MVLIF]. Phosphorylates EIF4G3/eIF4GII. In vitro phosphorylates CREB1, ATF1, CTFR, MYL9, SYN1/synapsin I and SYNII/synapsin II"|comment:mint	-	figure legend:2Bi, 3Bi|resulting-ptm:P02687 phosres|causality statement:A2A121decreases activity of Q63450.|comment:"The inhibitory polypeptide, zDCLK(678–810), showed weak inhibition of CaMKI."|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:7KJ2wmUk+WzmKMUkzS52jSWZ54w10116	rogid:+XOfpMhDq0quW7eKyc4SY6SHvXc9913	intact-crc:E28D60166783B9BB|rigid:nup3AFMOa9f1h3/TXJ4X3xe4hTM	false	phosphorylated residue:?-?|his tag:c-c|t7 tag:n-n	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	uniprotkb:P02687	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-908215|uniprotkb:Q9BGM8|uniprotkb:Q9TS63|uniprotkb:Q9TSA6	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:mbp_bovin(display_long)|uniprotkb:MBP(gene name)|psi-mi:MBP(display_short)|uniprotkb:Myelin A1 protein(gene name synonym)|uniprotkb:20 kDa microtubule-stabilizing protein(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006037|imex:IM-21794-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	mint:P02687|dip:DIP-29967N|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0071944"(cell periphery)|interpro:IPR000548(Myelin basic protein)|go:"GO:0005516"(calmodulin binding)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:1C, 2B, 3A/B|resulting-ptm:P02687 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:+XOfpMhDq0quW7eKyc4SY6SHvXc9913	intact-crc:4D36C8B6450E9E36|rigid:bYbYMGsJ0wQVskZQnNeD8LzDz0E	false	sufficient binding region:377-677(IPR000719)|necessary binding region:653-677|glutathione s tranferase tag:n-n|his tag:c-c	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	uniprotkb:A2A121	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006317|imex:IM-21794-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0033673"(negative regulation of kinase activity)	-	-	figure legend:2B|resulting-ptm:P02687 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	intact-crc:C69BE24B640B8D3F|rigid:bYbYMGsJ0wQVskZQnNeD8LzDz0E	false	his tag:c-c|glutathione s tranferase tag:n-n|necessary binding region:653-677|sufficient binding region:377-677(IPR000719)	sufficient binding region:678-810|glutathione s tranferase tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	uniprotkb:P02687	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-908215|uniprotkb:Q9BGM8|uniprotkb:Q9TS63|uniprotkb:Q9TSA6	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:mbp_bovin(display_long)|uniprotkb:MBP(gene name)|psi-mi:MBP(display_short)|uniprotkb:Myelin A1 protein(gene name synonym)|uniprotkb:20 kDa microtubule-stabilizing protein(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006317|imex:IM-21794-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	mint:P02687|dip:DIP-29967N|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0071944"(cell periphery)|interpro:IPR000548(Myelin basic protein)|go:"GO:0005516"(calmodulin binding)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0033673"(negative regulation of kinase activity)	-	-	figure legend:2B|resulting-ptm:P02687 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:+XOfpMhDq0quW7eKyc4SY6SHvXc9913	intact-crc:C69BE24B640B8D3F|rigid:bYbYMGsJ0wQVskZQnNeD8LzDz0E	false	his tag:c-c|glutathione s tranferase tag:n-n|necessary binding region:653-677|sufficient binding region:377-677(IPR000719)	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q63450	uniprotkb:P15337	intact:EBI-7007884|ensembl:ENSRNOP00000033456|intact:MINT-3375300|uniprotkb:Q63084	intact:EBI-973322|ensembl:ENSRNOP00000049369	psi-mi:kcc1a_rat(display_long)|uniprotkb:Camk1(gene name)|psi-mi:Camk1(display_short)|uniprotkb:CaM kinase I(gene name synonym)|uniprotkb:CaM kinase I alpha(gene name synonym)	psi-mi:creb1_rat(display_long)|uniprotkb:Creb1(gene name)|psi-mi:Creb1(display_short)|uniprotkb:Creb-1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006440|imex:IM-21794-6	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006237065.1|ensembl:ENSRNOG00000021781(gene)|ensembl:ENSRNOT00000029728(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0060143"(positive regulation of syncytium formation by plasma membrane fusion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q63450|rcsb pdb:1A06|rcsb pdb:1MXE|rcsb pdb:2L7L|reactome:R-RNO-9619229|refseq:NP_604463.1|rgd:629473	ensembl:ENSRNOG00000013412(gene)|go:"GO:0000785"(chromatin)|ensembl:ENSRNOT00000049654(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0060428"(lung epithelium development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|rcsb pdb:1KDX|reactome:R-RNO-198693|reactome:R-RNO-199920|reactome:R-RNO-375165|reactome:R-RNO-442742|reactome:R-RNO-881907|reactome:R-RNO-9031628|reactome:R-RNO-9634638|rgd:620218|refseq:NP_112279.1|refseq:NP_604392.1|refseq:XP_006245127.1|refseq:XP_006245128.1|dip:DIP-36407N	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	function:"Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes like transcriptional regulation, hormone production, translational regulation, regulation of actin filament organization and neurite outgrowth. Involved in calcium-dependent activation of the ERK pathway (By similarity). Recognizes the substrate consensus sequence [MVLIF]-x-R-x(2)-[ST]-x(3)-[MVLIF]. Phosphorylates EIF4G3/eIF4GII. In vitro phosphorylates CREB1, ATF1, CTFR, MYL9, SYN1/synapsin I and SYNII/synapsin II"|comment:mint	-	figure legend:3B|resulting-ptm:P15337 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2020/10/21	rogid:7KJ2wmUk+WzmKMUkzS52jSWZ54w10116	rogid:CwTrBzH0LR4Qlw71kKY1BmzXcuk10116	intact-crc:81E2195E9DC07F11|rigid:/0PUyDbgWtJy24A+fMz8aRQP584	false	his tag:c-c|phosphorylated residue:?-?|t7 tag:n-n	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	uniprotkb:C5NU62	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006516	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:c5nu62_danre(display_long)|uniprotkb:syn2b(gene name)|psi-mi:syn2b(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006830|imex:IM-21794-13	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR028712	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:"5D, 8B(RHS)"|resulting-ptm:C5NU62  ser-9 O-phospho-L-serine  C5NU62  ser-58 O-phospho-L-serine|comment:vector for synpasin 2 is derived form pET23+  - imidazole is in buffer used to elute from column, so presumably His tag is present.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:SXz0OM8CvNK/A9mpIsLy7LXwg5o7955	intact-crc:4F88EA729DA72220|rigid:DflHGIheXNeeZrptT9Lz3ihUxp8	false	his tag:c-c|glutathione s tranferase tag:n-n|sufficient binding region:377-677(IPR000719)	his tag:c-c|t7 tag:n-n|mutation decreasing interaction rate:9-9|mutation decreasing interaction rate:58-58	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	uniprotkb:B0UXI4	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006598|ensembl:ENSDARP00000115298|ensembl:ENSDARP00000154853	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:b0uxi4_danre(display_long)|uniprotkb:syn1(gene name)|psi-mi:syn1(display_short)|uniprotkb:"si:dkey-90n12.3"(gene name synonym)|uniprotkb:Synapsin-1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9007342|imex:IM-21794-18	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	refseq:NP_001119909.1|ensembl:ENSDARG00000060368(gene)|ensembl:ENSDARG00000111164(gene)|ensembl:ENSDART00000136578(transcript)|ensembl:ENSDART00000187537(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|reactome:R-DRE-181429|reactome:R-DRE-212676	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:"8B (RHS)"|resulting-ptm:B0UXI4  phosres|comment:vector for synpasin 1a is derived form pET23+  - imidazole is in buffer used to elute from column, so presumably His tag is present.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:jdFg9yb2lRy0Ynu7m8hDcDaf+1A7955	intact-crc:3CE5C7BF52433A74|rigid:VD98qoEOyITn4R0sUTjNPgGfIuk	false	sufficient binding region:377-677(IPR000719)|his tag:c-c|glutathione s tranferase tag:n-n	t7 tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	-	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	-	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	-	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9037464|imex:IM-21794-19	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	-	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:1C, 3A, 4A|resulting-ptm:A2A121  phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	-	intact-crc:0E7EA6A23B23E123	false	glutathione s tranferase tag:n-n|necessary binding region:653-677|sufficient binding region:377-677(IPR000719)|his tag:c-c	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	-
uniprotkb:C5NU62	uniprotkb:A2A121	intact:EBI-9006516	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	psi-mi:c5nu62_danre(display_long)|uniprotkb:syn2b(gene name)|psi-mi:syn2b(display_short)	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006549|imex:IM-21794-8	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR028712	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:5B|resulting-ptm:C5NU62  phosres|comment:vector for synpasin 2 is derived form pET23+  - imidazole is in buffer used to elute from column, so presumably His tag is present.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:SXz0OM8CvNK/A9mpIsLy7LXwg5o7955	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	intact-crc:8C0CCEBB00B2966E|rigid:DflHGIheXNeeZrptT9Lz3ihUxp8	false	his tag:c-c|t7 tag:n-n	sufficient binding region:377-677(IPR000719)|glutathione s tranferase tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:B0UXI4	uniprotkb:A2A121	intact:EBI-9006598|ensembl:ENSDARP00000115298|ensembl:ENSDARP00000154853	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	psi-mi:b0uxi4_danre(display_long)|uniprotkb:syn1(gene name)|psi-mi:syn1(display_short)|uniprotkb:"si:dkey-90n12.3"(gene name synonym)|uniprotkb:Synapsin-1(gene name synonym)	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006579|imex:IM-21794-9	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119909.1|ensembl:ENSDARG00000060368(gene)|ensembl:ENSDARG00000111164(gene)|ensembl:ENSDART00000136578(transcript)|ensembl:ENSDART00000187537(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|reactome:R-DRE-181429|reactome:R-DRE-212676	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:5Bi|resulting-ptm:B0UXI4  phosres|comment:vector for synpasin 1a is derived form pET23+  - imidazole is in buffer used to elute from column, so presumably His tag is present.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:jdFg9yb2lRy0Ynu7m8hDcDaf+1A7955	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	intact-crc:D1627315E7267DD8|rigid:VD98qoEOyITn4R0sUTjNPgGfIuk	false	t7 tag:n-n|his tag:c-c	his tag:c-c|glutathione s tranferase tag:n-n|sufficient binding region:377-677(IPR000719)	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:A2A121	uniprotkb:P02687	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-908215|uniprotkb:Q9BGM8|uniprotkb:Q9TS63|uniprotkb:Q9TSA6	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:mbp_bovin(display_long)|uniprotkb:MBP(gene name)|psi-mi:MBP(display_short)|uniprotkb:Myelin A1 protein(gene name synonym)|uniprotkb:20 kDa microtubule-stabilizing protein(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006668|imex:IM-21794-10	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	mint:P02687|dip:DIP-29967N|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0071944"(cell periphery)|interpro:IPR000548(Myelin basic protein)|go:"GO:0005516"(calmodulin binding)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:1D|resulting-ptm:P02687 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:+XOfpMhDq0quW7eKyc4SY6SHvXc9913	intact-crc:26DB09C427D1B7C7|rigid:bYbYMGsJ0wQVskZQnNeD8LzDz0E	false	sufficient binding region:377-677(IPR000719)|his tag:c-c|glutathione s tranferase tag:n-n|necessary binding region:653-677	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:A2A121	intact:EBI-1536909	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	-	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:syntide_2_peptide(display_short)|psi-mi:EBI-1536909(display_long)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9037892|imex:IM-21794-21	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	-	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:The native peptide PLARTLSVAGLPGKK is a selective Substrate for CaM kinase II and PKC. it is also a poor substrate for phosphorylase kinase and is not phosphorylated by myosin light chain kinase. The sequence of PLARTLSVAGLPGKK is homologous to phosphorylation site 2 in glycogen synthase.	figure legend:1E|resulting-ptm:syntide-2 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:plhkj+2Uljj+FC+b1vEI7VGxrnM-2	intact-crc:66218B8B155EA726|rigid:fu6iwEnXFoHsL0CwP6BYgcUFzNM	false	glutathione s tranferase tag:n-n|sufficient binding region:377-677(IPR000719)|necessary binding region:653-677|his tag:c-c	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:A2A121	uniprotkb:C5NU62	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006516	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:c5nu62_danre(display_long)|uniprotkb:syn2b(gene name)|psi-mi:syn2b(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006491|imex:IM-21794-7	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR028712	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:4|resulting-ptm:C5NU62  phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:SXz0OM8CvNK/A9mpIsLy7LXwg5o7955	intact-crc:15553DD0DA010EAD|rigid:DflHGIheXNeeZrptT9Lz3ihUxp8	false	his tag:c-c|sufficient binding region:377-677(IPR000719)|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:B0UXI4	uniprotkb:A2A121	intact:EBI-9006598|ensembl:ENSDARP00000115298|ensembl:ENSDARP00000154853	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	psi-mi:b0uxi4_danre(display_long)|uniprotkb:syn1(gene name)|psi-mi:syn1(display_short)|uniprotkb:"si:dkey-90n12.3"(gene name synonym)|uniprotkb:Synapsin-1(gene name synonym)	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006792|imex:IM-21794-12	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119909.1|ensembl:ENSDARG00000060368(gene)|ensembl:ENSDARG00000111164(gene)|ensembl:ENSDART00000136578(transcript)|ensembl:ENSDART00000187537(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|reactome:R-DRE-181429|reactome:R-DRE-212676	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:5C|resulting-ptm:B0UXI4  ser-9 O-phospho-L-serine|comment:vector for synpasin 1a is derived form pET23+  - imidazole is in buffer used to elute from column, so presumably His tag is present.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:jdFg9yb2lRy0Ynu7m8hDcDaf+1A7955	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	intact-crc:79B498CA21565D55|rigid:VD98qoEOyITn4R0sUTjNPgGfIuk	false	his tag:c-c|t7 tag:n-n	his tag:c-c|sufficient binding region:377-677(IPR000719)|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2A121	uniprotkb:C5NU62	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006516	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:c5nu62_danre(display_long)|uniprotkb:syn2b(gene name)|psi-mi:syn2b(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006753|imex:IM-21794-11	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR028712	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:5C|resulting-ptm:C5NU62  ser-9 O-phospho-L-serine|comment:vector for synpasin 2 is derived form pET23+  - imidazole is in buffer used to elute from column, so presumably His tag is present.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:SXz0OM8CvNK/A9mpIsLy7LXwg5o7955	intact-crc:0D8154CA8C2065BE|rigid:DflHGIheXNeeZrptT9Lz3ihUxp8	false	sufficient binding region:377-677(IPR000719)|glutathione s tranferase tag:n-n|his tag:c-c	t7 tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2A121	uniprotkb:C5NU62	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006516	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:c5nu62_danre(display_long)|uniprotkb:syn2b(gene name)|psi-mi:syn2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9007203|imex:IM-21794-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR028712	go:"GO:0043005"(neuron projection)	-	-	figure legend:7B|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7955(danre-brain)|taxid:7955(Danio rerio)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:SXz0OM8CvNK/A9mpIsLy7LXwg5o7955	intact-crc:F230B7C3842321BF|rigid:N1xS1/zqxWJQYFItovcBrrA91wU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2A121	uniprotkb:B0UXI4	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006598|ensembl:ENSDARP00000115298|ensembl:ENSDARP00000154853	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:b0uxi4_danre(display_long)|uniprotkb:syn1(gene name)|psi-mi:syn1(display_short)|uniprotkb:"si:dkey-90n12.3"(gene name synonym)|uniprotkb:Synapsin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9007203|imex:IM-21794-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	refseq:NP_001119909.1|ensembl:ENSDARG00000060368(gene)|ensembl:ENSDARG00000111164(gene)|ensembl:ENSDART00000136578(transcript)|ensembl:ENSDART00000187537(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|reactome:R-DRE-181429|reactome:R-DRE-212676	go:"GO:0043005"(neuron projection)	-	-	figure legend:7B|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7955(danre-brain)|taxid:7955(Danio rerio)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:jdFg9yb2lRy0Ynu7m8hDcDaf+1A7955	intact-crc:F230B7C3842321BF|rigid:N1xS1/zqxWJQYFItovcBrrA91wU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2A121	uniprotkb:C5NU62	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006516	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:c5nu62_danre(display_long)|uniprotkb:syn2b(gene name)|psi-mi:syn2b(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006908|imex:IM-21794-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR028712	-	-	-	figure legend:6B|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:SXz0OM8CvNK/A9mpIsLy7LXwg5o7955	intact-crc:F7A1188C4DF1BE39|rigid:DflHGIheXNeeZrptT9Lz3ihUxp8	false	necessary binding region:377-677(IPR000719)|flag tag:n-n	myc tag:c-c|his tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:B0UXI4	uniprotkb:A2A121	intact:EBI-9006598|ensembl:ENSDARP00000115298|ensembl:ENSDARP00000154853	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	psi-mi:b0uxi4_danre(display_long)|uniprotkb:syn1(gene name)|psi-mi:syn1(display_short)|uniprotkb:"si:dkey-90n12.3"(gene name synonym)|uniprotkb:Synapsin-1(gene name synonym)	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9007285|imex:IM-21794-17	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119909.1|ensembl:ENSDARG00000060368(gene)|ensembl:ENSDARG00000111164(gene)|ensembl:ENSDART00000136578(transcript)|ensembl:ENSDART00000187537(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|reactome:R-DRE-181429|reactome:R-DRE-212676	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:8Bi|resulting-ptm:A2A121 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:jdFg9yb2lRy0Ynu7m8hDcDaf+1A7955	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	intact-crc:64B7C0093D736399|rigid:VD98qoEOyITn4R0sUTjNPgGfIuk	false	-	glutathione s tranferase tag:n-n|his tag:c-c|sufficient binding region:377-677(IPR000719)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:A2A121	uniprotkb:C5NU62	intact:EBI-9006039|ensembl:ENSDARP00000151206|ensembl:ENSDARP00000152389	intact:EBI-9006516	psi-mi:a2a121_danre(display_long)|uniprotkb:dclk2a(gene name)|psi-mi:dclk2a(display_short)|uniprotkb:dclk2(gene name synonym)	psi-mi:c5nu62_danre(display_long)|uniprotkb:syn2b(gene name)|psi-mi:syn2b(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Shimomura et al. (2010)	pubmed:20097902|imex:IM-21794	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9007246|imex:IM-21794-16	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128593.1|ensembl:ENSDARG00000034093(gene)|ensembl:ENSDART00000191004(transcript)|ensembl:ENSDART00000192580(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572|interpro:IPR017441(Protein kinase ATP binding, conserved site)	interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR028712	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:8B|resulting-ptm:A2A121 phosres|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/11/29	2014/10/16	rogid:3usfAZABUOiATfCXO4Nfq6ss2GY7955	rogid:SXz0OM8CvNK/A9mpIsLy7LXwg5o7955	intact-crc:DCC6A8C0A1DFBB0E|rigid:DflHGIheXNeeZrptT9Lz3ihUxp8	false	sufficient binding region:377-677(IPR000719)|glutathione s tranferase tag:n-n|his tag:c-c	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)