#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15066 uniprotkb:O15013 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 intact:EBI-2515636|uniprotkb:Q2KHR8|uniprotkb:Q8IY77|uniprotkb:Q68D55|uniprotkb:O14665|uniprotkb:Q8IWD9|ensembl:ENSP00000381571|ensembl:ENSP00000481974 psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:arhga_human(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:"MI:0018"(two hybrid) Aoki et al. (2009) pubmed:19635168|imex:IM-22102 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-6927722|imex:IM-22102-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 refseq:NP_001295081.1|refseq:NP_001295082.1|refseq:XP_016869492.1|refseq:NP_055444.2|ensembl:ENSG00000104728(gene)|ensembl:ENSG00000274726(gene)|ensembl:ENST00000398564(transcript)|ensembl:ENST00000610399(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR030632|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0019894"(kinesin binding) - - - figure legend:Fig 5A|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/08/14 2014/10/16 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 rogid:ItJsuYi6vx3O1aAzi4Jz1OXS2hI9606 intact-crc:C04D2C90CABF5456|rigid:We9gAGBINQItZFGoah2670H+hyg false sufficient binding region:480-747 sufficient binding region:1-1083 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15013 uniprotkb:O15066 intact:EBI-2515636|uniprotkb:Q2KHR8|uniprotkb:Q8IY77|uniprotkb:Q68D55|uniprotkb:O14665|uniprotkb:Q8IWD9|ensembl:ENSP00000381571|ensembl:ENSP00000481974 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 psi-mi:arhga_human(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Aoki et al. (2009) pubmed:19635168|imex:IM-22102 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-6927741|imex:IM-22102-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295081.1|refseq:NP_001295082.1|refseq:XP_016869492.1|refseq:NP_055444.2|ensembl:ENSG00000104728(gene)|ensembl:ENSG00000274726(gene)|ensembl:ENST00000398564(transcript)|ensembl:ENST00000610399(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR030632|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0019894"(kinesin binding) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 go:"GO:0005813"(centrosome) - - figure legend:Fig 5B|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2013/08/14 2014/10/16 rogid:ItJsuYi6vx3O1aAzi4Jz1OXS2hI9606 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 intact-crc:AA561264F2A92E42|rigid:We9gAGBINQItZFGoah2670H+hyg false - flag tag:n-n - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O15013 uniprotkb:O15066 intact:EBI-2515636|uniprotkb:Q2KHR8|uniprotkb:Q8IY77|uniprotkb:Q68D55|uniprotkb:O14665|uniprotkb:Q8IWD9|ensembl:ENSP00000381571|ensembl:ENSP00000481974 intact:EBI-3931791|uniprotkb:E1P5M5|uniprotkb:B2RMP4|ensembl:ENSP00000364864|uniprotkb:B4DSR5 psi-mi:arhga_human(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:kif3b_human(display_long)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Aoki et al. (2009) pubmed:19635168|imex:IM-22102 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-6927768|imex:IM-22102-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001295081.1|refseq:NP_001295082.1|refseq:XP_016869492.1|refseq:NP_055444.2|ensembl:ENSG00000104728(gene)|ensembl:ENSG00000274726(gene)|ensembl:ENST00000398564(transcript)|ensembl:ENST00000610399(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR030632|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0019894"(kinesin binding) ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005873"(plus-end kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016939"(kinesin II complex)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|rcsb pdb:3B6U|reactome:R-HSA-1445148|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0016020"(membrane)|refseq:NP_004789.1 - - - figure legend:Fig 5C|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/08/14 2014/10/16 rogid:ItJsuYi6vx3O1aAzi4Jz1OXS2hI9606 rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 intact-crc:433A2F9CF06528FD|rigid:We9gAGBINQItZFGoah2670H+hyg false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)