#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q18688	uniprotkb:O16259	intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4	intact:EBI-6514174|ensemblmetazoa:R09E12.3.1	psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name)	psi-mi:stip1_caeel(display_long)|uniprotkb:sti-1(gene name)|psi-mi:sti-1(display_short)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:R09E12.3(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6917553|imex:IM-22058-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282	ensemblmetazoa:R09E12.3.1(transcript)|ensemblmetazoa:WBGene00019983(gene)|go:"GO:0000003"(reproduction)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|refseq:NP_503322.1|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:4GCN|rcsb pdb:4GCO|wormbase:R09E12.3|interpro:IPR041243|reactome:R-CEL-3371497	-	-	-	figure legend:Fig 3b, 3C, Table 3|comment:"Both the N-terminal (1-131) and C-terminal (191-32) domains of sti-1 were capable of weakly binding sti_1"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.04x10^-7(molar)	2013/02/14	2014/10/16	rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239	rogid:XgJZ4fAj22XuqwDIcbiHdYiUlos6239	intact-crc:FA6104EFF2530954|rigid:eqghDW9VdM2XV1wiY3nmOw86COI	false	necessary binding region:698-702	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O16259	uniprotkb:P09446	intact:EBI-6514174|ensemblmetazoa:R09E12.3.1	intact:EBI-322448|uniprotkb:Q93601|ensemblmetazoa:F26D10.3.1|ensemblmetazoa:F26D10.3.2	psi-mi:stip1_caeel(display_long)|uniprotkb:sti-1(gene name)|psi-mi:sti-1(display_short)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:R09E12.3(orf name)	psi-mi:hsp1_caeel(display_long)|uniprotkb:hsp-1(gene name)|psi-mi:hsp-1(display_short)|uniprotkb:hsp70a(gene name synonym)|uniprotkb:F26D10.3(orf name)|uniprotkb:Heat shock 70 kDa protein A(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6918510|imex:IM-22058-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:R09E12.3.1(transcript)|ensemblmetazoa:WBGene00019983(gene)|go:"GO:0000003"(reproduction)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|refseq:NP_503322.1|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:4GCN|rcsb pdb:4GCO|wormbase:R09E12.3|interpro:IPR041243|reactome:R-CEL-3371497	refseq:NP_503068.1|wormbase:F26D10.3|reactome:R-CEL-3371453|ensemblmetazoa:F26D10.3.1(transcript)|ensemblmetazoa:F26D10.3.2(transcript)|ensemblmetazoa:WBGene00002005(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2P32|rcsb pdb:4I2W|reactome:R-CEL-72163|reactome:R-CEL-6798695|reactome:R-CEL-3371571|reactome:R-CEL-8856828|dip:DIP-26882N|reactome:R-CEL-3371497|reactome:R-CEL-888590	-	-	-	figure legend:Fig. 4a, Table 3|comment:"Both the N-terminal (1-131) and C-terminal (191-32) domains of sti-1 were capable of weakly binding hsc-70"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.7x10^-6(molar)	2013/02/14	2014/10/16	rogid:XgJZ4fAj22XuqwDIcbiHdYiUlos6239	rogid:9ydEtLk204NKqMg4mSg+Oit/t0I6239	intact-crc:4127CD532F8F773E|rigid:zsFJ6yqUQ1pUIUtgvPT871ePvHI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09446	uniprotkb:O16259	intact:EBI-322448|uniprotkb:Q93601|ensemblmetazoa:F26D10.3.1|ensemblmetazoa:F26D10.3.2	intact:EBI-6514174|ensemblmetazoa:R09E12.3.1	psi-mi:hsp1_caeel(display_long)|uniprotkb:hsp-1(gene name)|psi-mi:hsp-1(display_short)|uniprotkb:hsp70a(gene name synonym)|uniprotkb:F26D10.3(orf name)|uniprotkb:Heat shock 70 kDa protein A(gene name synonym)	psi-mi:stip1_caeel(display_long)|uniprotkb:sti-1(gene name)|psi-mi:sti-1(display_short)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:R09E12.3(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6918699|imex:IM-22058-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_503068.1|wormbase:F26D10.3|reactome:R-CEL-3371453|ensemblmetazoa:F26D10.3.1(transcript)|ensemblmetazoa:F26D10.3.2(transcript)|ensemblmetazoa:WBGene00002005(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2P32|rcsb pdb:4I2W|reactome:R-CEL-72163|reactome:R-CEL-6798695|reactome:R-CEL-3371571|reactome:R-CEL-8856828|dip:DIP-26882N|reactome:R-CEL-3371497|reactome:R-CEL-888590	ensemblmetazoa:R09E12.3.1(transcript)|ensemblmetazoa:WBGene00019983(gene)|go:"GO:0000003"(reproduction)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|refseq:NP_503322.1|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:4GCN|rcsb pdb:4GCO|wormbase:R09E12.3|interpro:IPR041243|reactome:R-CEL-3371497	-	-	-	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/14	2014/10/16	rogid:9ydEtLk204NKqMg4mSg+Oit/t0I6239	rogid:XgJZ4fAj22XuqwDIcbiHdYiUlos6239	intact-crc:130D71FB060F0B2F|rigid:j1no0bZkdQLHMZQN79Seer8woGA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09446	uniprotkb:Q18688	intact:EBI-322448|uniprotkb:Q93601|ensemblmetazoa:F26D10.3.1|ensemblmetazoa:F26D10.3.2	intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4	psi-mi:hsp1_caeel(display_long)|uniprotkb:hsp-1(gene name)|psi-mi:hsp-1(display_short)|uniprotkb:hsp70a(gene name synonym)|uniprotkb:F26D10.3(orf name)|uniprotkb:Heat shock 70 kDa protein A(gene name synonym)	psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6918699|imex:IM-22058-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_503068.1|wormbase:F26D10.3|reactome:R-CEL-3371453|ensemblmetazoa:F26D10.3.1(transcript)|ensemblmetazoa:F26D10.3.2(transcript)|ensemblmetazoa:WBGene00002005(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2P32|rcsb pdb:4I2W|reactome:R-CEL-72163|reactome:R-CEL-6798695|reactome:R-CEL-3371571|reactome:R-CEL-8856828|dip:DIP-26882N|reactome:R-CEL-3371497|reactome:R-CEL-888590	refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282	-	-	-	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/14	2014/10/16	rogid:9ydEtLk204NKqMg4mSg+Oit/t0I6239	rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239	intact-crc:130D71FB060F0B2F|rigid:j1no0bZkdQLHMZQN79Seer8woGA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O16259	uniprotkb:Q18688	intact:EBI-6514174|ensemblmetazoa:R09E12.3.1	intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4	psi-mi:stip1_caeel(display_long)|uniprotkb:sti-1(gene name)|psi-mi:sti-1(display_short)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:R09E12.3(orf name)	psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name)	psi-mi:"MI:0096"(pull down)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6514284|imex:IM-22058-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:R09E12.3.1(transcript)|ensemblmetazoa:WBGene00019983(gene)|go:"GO:0000003"(reproduction)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|refseq:NP_503322.1|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:4GCN|rcsb pdb:4GCO|wormbase:R09E12.3|interpro:IPR041243|reactome:R-CEL-3371497	refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282	-	-	-	figure legend:Fig 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/14	2014/10/16	rogid:XgJZ4fAj22XuqwDIcbiHdYiUlos6239	rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239	intact-crc:C84EBDE30E9BCE72|rigid:eqghDW9VdM2XV1wiY3nmOw86COI	false	his tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:15422"	uniprotkb:Q18688	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name)	psi-mi:"MI:0880"(atpase assay)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9104038|imex:IM-22058-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/14	2014/10/16	-	rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239	intact-crc:D80F3EC1F7C2B43F	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:O16259	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-6514174|ensemblmetazoa:R09E12.3.1	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:stip1_caeel(display_long)|uniprotkb:sti-1(gene name)|psi-mi:sti-1(display_short)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:R09E12.3(orf name)	psi-mi:"MI:0880"(atpase assay)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9104038|imex:IM-22058-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblmetazoa:R09E12.3.1(transcript)|ensemblmetazoa:WBGene00019983(gene)|go:"GO:0000003"(reproduction)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|refseq:NP_503322.1|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:4GCN|rcsb pdb:4GCO|wormbase:R09E12.3|interpro:IPR041243|reactome:R-CEL-3371497	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/14	2014/10/16	-	rogid:XgJZ4fAj22XuqwDIcbiHdYiUlos6239	intact-crc:D80F3EC1F7C2B43F	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P09446	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-322448|uniprotkb:Q93601|ensemblmetazoa:F26D10.3.1|ensemblmetazoa:F26D10.3.2	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hsp1_caeel(display_long)|uniprotkb:hsp-1(gene name)|psi-mi:hsp-1(display_short)|uniprotkb:hsp70a(gene name synonym)|uniprotkb:F26D10.3(orf name)|uniprotkb:Heat shock 70 kDa protein A(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6918632|imex:IM-22058-6	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_503068.1|wormbase:F26D10.3|reactome:R-CEL-3371453|ensemblmetazoa:F26D10.3.1(transcript)|ensemblmetazoa:F26D10.3.2(transcript)|ensemblmetazoa:WBGene00002005(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2P32|rcsb pdb:4I2W|reactome:R-CEL-72163|reactome:R-CEL-6798695|reactome:R-CEL-3371571|reactome:R-CEL-8856828|dip:DIP-26882N|reactome:R-CEL-3371497|reactome:R-CEL-888590	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/14	2014/10/16	-	rogid:9ydEtLk204NKqMg4mSg+Oit/t0I6239	intact-crc:0B5D72EF709C760E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q18688	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name)	psi-mi:"MI:0880"(atpase assay)	Gaiser et al. (2009)	pubmed:19559711|imex:IM-22058	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-9104032|imex:IM-22058-7	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282	go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0006200"(obsolete ATP catabolic process)	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/14	2014/10/16	-	rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239	intact-crc:5B62EBC9361E9048	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)