#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P9WJA9	uniprotkb:P9WIS5	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	intact:EBI-6405560|uniprotkb:O50463|uniprotkb:Q7D8I9|uniprotkb:L0T8T9	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:kgd_myctu(display_long)|uniprotkb:kgd(gene name)|psi-mi:kgd(display_short)|uniprotkb:2-hydroxy-3-oxoadipate synthase(gene name synonym)|uniprotkb:2-oxoglutarate carboxy-lyase(gene name synonym)|uniprotkb:2-oxoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate-glyoxylate carboligase(gene name synonym)|uniprotkb:Rv1248c(locus name)	psi-mi:"MI:0096"(pull down)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8839054|imex:IM-21717-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	go:"GO:0000287"(magnesium ion binding)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0008683"(2-oxoglutarate decarboxylase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016624"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0050439"(2-hydroxy-3-oxoadipate synthase activity)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR023213|refseq:WP_003898790.1|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|refseq:NP_215764.2|interpro:IPR042179	-	-	-	figure legend:Fig. 1b, Fig. 5c, Suppl. Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	rogid:wnsh2XIKp9xaQSnRTQoNKTKmyZo83332	intact-crc:3046BF7D83E0FFA6|rigid:y6GxZNXyNUfqiT5PQpqLGAIMixU	false	glutathione s tranferase tag:?-?|mutation disrupting interaction:141-141|mutation disrupting interaction:117-117|O-phospho-L-threonine:22-22|mutation disrupting interaction:143-143|sufficient binding region:55-149(IPR000253)	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P96218	uniprotkb:P9WJA9	intact:EBI-8839139|uniprotkb:F2GDM1|uniprotkb:L0TDS2	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	psi-mi:gltb_myctu(display_long)|uniprotkb:gltB(gene name)|psi-mi:gltB(display_short)|uniprotkb:Glutamate synthase subunit alpha(gene name synonym)|uniprotkb:Rv3859c(locus name)	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:"MI:0096"(pull down)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8839164|imex:IM-21717-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003899733.1|interpro:IPR029055|refseq:NP_218376.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017932|interpro:IPR002489(Glutamate synthase, alpha subunit, C-terminal)|interpro:IPR002932(Glutamate synthase, central-C)|interpro:IPR006982(Glutamate synthase, central-N)|interpro:IPR036485|go:"GO:0004355"("glutamate synthase (NADPH) activity")|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0015930"(glutamate synthase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019676"(ammonia assimilation cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0097054"(L-glutamate biosynthetic process)	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	-	-	-	figure legend:Fig. 1b, Fig. 5c, Suppl. Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:lBHjDREafhtUPPRQaA3oZuY6F6883332	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	intact-crc:46F724703174A105|rigid:/g9hGlhj63Et8lkm7UG+ZlepgZI	false	-	sufficient binding region:55-149(IPR000253)|mutation disrupting interaction:95-95|mutation disrupting interaction:141-141|glutathione s tranferase tag:?-?|mutation disrupting interaction:117-117|O-phospho-L-threonine:22-22	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P9WJA9	uniprotkb:O53203	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	intact:EBI-6405569|uniprotkb:L0T9R1	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:dhe2_myctu(display_long)|uniprotkb:gdh(gene name)|psi-mi:gdh(display_short)|uniprotkb:"NAD(+)-dependent glutamate dehydrogenase"(gene name synonym)|uniprotkb:Rv2476c(locus name)	psi-mi:"MI:0096"(pull down)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8839177|imex:IM-21717-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR028971|refseq:WP_003916039.1|interpro:IPR007780(Bacterial NAD-glutamate dehydrogenase)|refseq:NP_216992.1|interpro:IPR036291	-	-	-	figure legend:Fig. 1b, Fig. 5c, Suppl. Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	rogid:8be/p2/CUxOL4km7m9ZPUWFfUXM83332	intact-crc:72F5F7417648DB1E|rigid:QCmvDYpW7p/Xrrt7P8yKzCSEOsA	false	O-phospho-L-threonine:22-22|sufficient binding region:55-149(IPR000253)|mutation disrupting interaction:141-141|mutation disrupting interaction:143-143|glutathione s tranferase tag:?-?|mutation decreasing interaction:95-95	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P9WJA9	uniprotkb:P9WJA9	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8839226|imex:IM-21717-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	-	-	-	figure legend:Suppl. Fig. S2, Suppl. Table S2|kinetic_conditions:Temp = 20C, pH = 8.0|kinetics:"Gara peptide (residues 16-28) phosphorylated at thr21 bound to full length Gara with Kd = 22.8 x 10E-6 molar and to Gara-fha (residues 55-149) with Kd = 9.6 x 10E-6 molar. Gara peptide (residues 16-28) phosphorylated at thr22 bound to full length Gara with Kd = 12.6 x 10E-6 molar and to Gara-fha (residues 55-149) with Kd = 4.2 x 10E-6 molar."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	intact-crc:E00F8CD100EAB2CE|rigid:Ywnu5rwE497aGjCVXmz8DkgnbOg	false	sufficient binding region:16-28(LIG_FHA_1)|O-phospho-L-threonine:22-22|O-phospho-L-threonine:21-21	sufficient binding region:55-149(IPR000253)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIS5	uniprotkb:P9WJA9	intact:EBI-6405560|uniprotkb:O50463|uniprotkb:Q7D8I9|uniprotkb:L0T8T9	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	psi-mi:kgd_myctu(display_long)|uniprotkb:kgd(gene name)|psi-mi:kgd(display_short)|uniprotkb:2-hydroxy-3-oxoadipate synthase(gene name synonym)|uniprotkb:2-oxoglutarate carboxy-lyase(gene name synonym)|uniprotkb:2-oxoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate-glyoxylate carboligase(gene name synonym)|uniprotkb:Rv1248c(locus name)	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8839341|imex:IM-21717-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000287"(magnesium ion binding)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0008683"(2-oxoglutarate decarboxylase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016624"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0050439"(2-hydroxy-3-oxoadipate synthase activity)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR023213|refseq:WP_003898790.1|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|refseq:NP_215764.2|interpro:IPR042179	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	-	-	-	figure legend:Fig 5c|causality statement:P64897 decreases activity of O50463|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:wnsh2XIKp9xaQSnRTQoNKTKmyZo83332	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	intact-crc:14BFA05D8349773F|rigid:y6GxZNXyNUfqiT5PQpqLGAIMixU	false	-	mutation disrupting interaction:117-117|mutation disrupting interaction:141-141|mutation disrupting interaction:143-143	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJA9	uniprotkb:O53203	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	intact:EBI-6405569|uniprotkb:L0T9R1	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:dhe2_myctu(display_long)|uniprotkb:gdh(gene name)|psi-mi:gdh(display_short)|uniprotkb:"NAD(+)-dependent glutamate dehydrogenase"(gene name synonym)|uniprotkb:Rv2476c(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8839371|imex:IM-21717-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR028971|refseq:WP_003916039.1|interpro:IPR007780(Bacterial NAD-glutamate dehydrogenase)|refseq:NP_216992.1|interpro:IPR036291	-	-	-	figure legend:Fig. 5c|causality statement:P64897 decreases activity of O53203|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	rogid:8be/p2/CUxOL4km7m9ZPUWFfUXM83332	intact-crc:8E5A30A285117492|rigid:QCmvDYpW7p/Xrrt7P8yKzCSEOsA	false	mutation disrupting interaction:141-141|mutation disrupting interaction:143-143|mutation decreasing interaction:95-95|mutation decreasing interaction:117-117	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJA9	uniprotkb:P9WJA9	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8839476|imex:IM-21717-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	-	-	-	figure legend:Fig. 3, 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	intact-crc:3A1EEA5577394E19|rigid:Ywnu5rwE497aGjCVXmz8DkgnbOg	false	sufficient binding region:16-28(LIG_FHA_1)|O-phospho-L-threonine:22-22	glutathione s tranferase tag:n-n|15n label:?-?|13c label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WI81	uniprotkb:P9WJA9	intact:EBI-2946037|uniprotkb:L0T5F6|uniprotkb:P71584|uniprotkb:P0A5S4	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	psi-mi:pknb_myctu(display_long)|uniprotkb:pknB(gene name)|psi-mi:pknB(display_short)|uniprotkb:MTCY10H4.14c(orf name)|uniprotkb:Rv0014c(locus name)	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8844423|imex:IM-21717-9	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0052572"(response to host immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:1MRU|rcsb pdb:1O6Y|rcsb pdb:2FUM|rcsb pdb:2KUD|rcsb pdb:2KUE|rcsb pdb:2KUF|rcsb pdb:2KUI|rcsb pdb:3F61|rcsb pdb:3F69|rcsb pdb:3ORI|rcsb pdb:3ORO|rcsb pdb:5E0Y|rcsb pdb:5E0Z|rcsb pdb:5E10|rcsb pdb:5U94|rcsb pdb:6B2P|rcsb pdb:6I2P|rcsb pdb:5E12|refseq:NP_214528.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR005543(PASTA)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003400356.1|mint:P9WI81	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	-	crc64:6C27EEBE9D5A453B	-	figure legend:Suppl. Fig. S3a|resulting-ptm:P64897 thr-22 O-phospho-L-threonine|causality statement:P0A5S4 decreases activity of P64897|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:KZ9ghc/5dguERQl5GY7dMe8Zc2I83332	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	intact-crc:104708BAE68A118F|rigid:m9yyi/Z4FIKo7MqjwJPnxNuodcM	false	sufficient binding region:1-279(IPR002290)	15n label:?-?|O-phospho-L-threonine:22-22|13c label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	uniprotkb:P9WJA9	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:"MI:1138"(decarboxylation assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8844498|imex:IM-21717-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1c, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	intact-crc:56901AC0051AC6E5	false	-	mutation disrupting interaction:141-141|sufficient binding region:55-149(IPR000253)|O-phospho-L-threonine:22-22|mutation disrupting interaction:117-117|mutation disrupting interaction:143-143	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	uniprotkb:P9WIS5	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-6405560|uniprotkb:O50463|uniprotkb:Q7D8I9|uniprotkb:L0T8T9	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:kgd_myctu(display_long)|uniprotkb:kgd(gene name)|psi-mi:kgd(display_short)|uniprotkb:2-hydroxy-3-oxoadipate synthase(gene name synonym)|uniprotkb:2-oxoglutarate carboxy-lyase(gene name synonym)|uniprotkb:2-oxoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate-glyoxylate carboligase(gene name synonym)|uniprotkb:Rv1248c(locus name)	psi-mi:"MI:1138"(decarboxylation assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8844498|imex:IM-21717-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0000287"(magnesium ion binding)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0008683"(2-oxoglutarate decarboxylase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016624"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0050439"(2-hydroxy-3-oxoadipate synthase activity)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR023213|refseq:WP_003898790.1|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|refseq:NP_215764.2|interpro:IPR042179	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1c, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	rogid:wnsh2XIKp9xaQSnRTQoNKTKmyZo83332	intact-crc:56901AC0051AC6E5	false	-	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	uniprotkb:P9WIS5	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-6405560|uniprotkb:O50463|uniprotkb:Q7D8I9|uniprotkb:L0T8T9	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:kgd_myctu(display_long)|uniprotkb:kgd(gene name)|psi-mi:kgd(display_short)|uniprotkb:2-hydroxy-3-oxoadipate synthase(gene name synonym)|uniprotkb:2-oxoglutarate carboxy-lyase(gene name synonym)|uniprotkb:2-oxoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate decarboxylase(gene name synonym)|uniprotkb:Alpha-ketoglutarate-glyoxylate carboligase(gene name synonym)|uniprotkb:Rv1248c(locus name)	psi-mi:"MI:1138"(decarboxylation assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:1140"(decarboxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873227|imex:IM-21717-12	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0000287"(magnesium ion binding)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0008683"(2-oxoglutarate decarboxylase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016624"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0050439"(2-hydroxy-3-oxoadipate synthase activity)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR023213|refseq:WP_003898790.1|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|refseq:NP_215764.2|interpro:IPR042179	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1c, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	rogid:wnsh2XIKp9xaQSnRTQoNKTKmyZo83332	intact-crc:673410A2978B56EB	false	-	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	uniprotkb:O53203	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-6405569|uniprotkb:L0T9R1	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:dhe2_myctu(display_long)|uniprotkb:gdh(gene name)|psi-mi:gdh(display_short)|uniprotkb:"NAD(+)-dependent glutamate dehydrogenase"(gene name synonym)|uniprotkb:Rv2476c(locus name)	psi-mi:"MI:0979"(oxidoreductase assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873242|imex:IM-21717-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR028971|refseq:WP_003916039.1|interpro:IPR007780(Bacterial NAD-glutamate dehydrogenase)|refseq:NP_216992.1|interpro:IPR036291	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1d, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	rogid:8be/p2/CUxOL4km7m9ZPUWFfUXM83332	intact-crc:A2930BABA5471F85	false	-	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	chebi:"CHEBI:16908"	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-4421847	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:nadh(display_short)|psi-mi:"CHEBI:16908"(display_long)	psi-mi:"MI:0979"(oxidoreductase assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8873242|imex:IM-21717-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1d, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	-	intact-crc:A2930BABA5471F85	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	uniprotkb:O53203	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-6405569|uniprotkb:L0T9R1	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:dhe2_myctu(display_long)|uniprotkb:gdh(gene name)|psi-mi:gdh(display_short)|uniprotkb:"NAD(+)-dependent glutamate dehydrogenase"(gene name synonym)|uniprotkb:Rv2476c(locus name)	psi-mi:"MI:0979"(oxidoreductase assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8844565|imex:IM-21717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|interpro:IPR028971|refseq:WP_003916039.1|interpro:IPR007780(Bacterial NAD-glutamate dehydrogenase)|refseq:NP_216992.1|interpro:IPR036291	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1d, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	rogid:8be/p2/CUxOL4km7m9ZPUWFfUXM83332	intact-crc:1F8A21503B8FB9E0	false	-	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	uniprotkb:P9WJA9	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-6405522|uniprotkb:I3V6A5|uniprotkb:P64897|uniprotkb:Q50606	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:gara_myctu(display_long)|uniprotkb:MTCY1A11.16c(orf name)|uniprotkb:Rv1827(locus name)|uniprotkb:garA(gene name)|psi-mi:garA(display_short)	psi-mi:"MI:0979"(oxidoreductase assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8844565|imex:IM-21717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046777"(protein autophosphorylation)|rcsb pdb:2KFU|rcsb pdb:6I2P|mint:P9WJA9|refseq:WP_003899041.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|refseq:NP_216343.1	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1d, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	rogid:cpnICH5xaIAtVWEyiFy2N7YRkuo83332	intact-crc:1F8A21503B8FB9E0	false	-	O-phospho-L-threonine:22-22|mutation disrupting interaction:143-143|sufficient binding region:55-149(IPR000253)|mutation disrupting interaction:95-95|mutation disrupting interaction:141-141|mutation decreasing interaction:117-117	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	chebi:"CHEBI:16908"	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-4421847	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:nadh(display_short)|psi-mi:"CHEBI:16908"(display_long)	psi-mi:"MI:0979"(oxidoreductase assay)	Nott et al. (2009)	pubmed:19318624|imex:IM-21717	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8844565|imex:IM-21717-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	figure legend:Fig. 1d, Suppl. Fig. S6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	-	-	intact-crc:1F8A21503B8FB9E0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)