#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P75830	uniprotkb:P75830	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8764343|imex:IM-21414-1|wwpdb:3fpp	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	-	-	-	figure legend:Fig.s 1b, 1c, 1d, 2, 3, S4|3d-r-factors:All = 0.29; Rwork = 0.28; Rfree = 0.35|3d-resolution:2.99 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	intact-crc:75CC90666407A6A2|rigid:YOAhxB9NB9Pl8YTzMERvLmCjAOg	false	sufficient binding region:32-371	sufficient binding region:32-371	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2EHL9	uniprotkb:Q2EHL9	intact:EBI-8765079	intact:EBI-8765079	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765134|imex:IM-21414-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	-	-	-	figure legend:"Fig. 5b (lower panel)"|comment:"The estimated molecular weight of the WT of the filtered product corresponds roughly to a hexameric conformation (210 kD).   This double mutant elutes at roughly the size of a trimer (120 kD) and dimer (70 kD)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	intact-crc:CE315FFD09E7F7F6|rigid:CJyJa9LocLlPcPbDQFu+PtlftNs	false	mutation:227-227,291-291|sufficient binding region:38-318	mutation:227-227,291-291|sufficient binding region:38-318	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2EHL9	uniprotkb:Q2EHL9	intact:EBI-8765079	intact:EBI-8765079	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765126|imex:IM-21414-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	-	-	-	figure legend:"Fig. 5b (upper panel)"|comment:"The estimated molecular weight of the WT of the filtered product corresponds roughly to a hexameric conformation (210 kD).   2/3 of this mutant elute in roughly hexamers while the remaining 1/3 elutes as roughly dimers (70 kD)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	intact-crc:27E2F8803F0C1EDF|rigid:CJyJa9LocLlPcPbDQFu+PtlftNs	false	mutation:227-227|sufficient binding region:38-318	mutation:227-227|sufficient binding region:38-318	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2EHL9	uniprotkb:Q2EHL9	intact:EBI-8765079	intact:EBI-8765079	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8848237|imex:IM-21414-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	-	-	-	figure legend:"Fig. 5b (upper panel)"|comment:"The estimated molecular weight of the WT of the filtered product corresponds roughly to a hexameric conformation (210 kD).   2/3 of this mutant elute in roughly hexamers while the remaining 1/3 elutes as roughly dimers (70 kD)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	intact-crc:3A5E21A047183B0B|rigid:CJyJa9LocLlPcPbDQFu+PtlftNs	false	sufficient binding region:38-318|mutation:227-227	sufficient binding region:38-318|mutation:227-227	3	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2EHL9	uniprotkb:Q2EHL9	intact:EBI-8765079	intact:EBI-8765079	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8848256|imex:IM-21414-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	-	-	-	figure legend:"Fig. 5b (lower panel)"|comment:"The estimated molecular weight of the WT of the filtered product corresponds roughly to a hexameric conformation (210 kD).   This double mutant elutes at roughly the size of a trimer (120 kD) and dimer (70 kD)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	intact-crc:74DC91F572EF3D4F|rigid:CJyJa9LocLlPcPbDQFu+PtlftNs	false	mutation:227-227,291-291|sufficient binding region:38-318	mutation:227-227,291-291|sufficient binding region:38-318	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2EHL9	uniprotkb:Q2EHL9	intact:EBI-8765079	intact:EBI-8765079	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765087|imex:IM-21414-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	-	-	-	figure legend:Fig. 4a, S6|comment:"Two truncated WT versions of this protein were put through the filter column: 20-394 aa and 38-318 aa.  The estimated molecular weight of the filtered products (210 and 200 kD) corresponds roughly to a hexameric conformation. The shorter construct (38-318 aa) also elutes at 60 kD which corresponds roughly to a dimer (Fig. S6).  The authors state in the legend: \"Aa MacA is hexameric in solution.\"  The crystal structure (Fig.s 1-3) and electron microscopy picture (Fig. 4b) also suggests a hexameric conformation."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	intact-crc:BDB1C823C03DE763|rigid:CJyJa9LocLlPcPbDQFu+PtlftNs	false	sufficient binding region:38-318	sufficient binding region:38-318	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2EHL9	uniprotkb:Q2EHL9	intact:EBI-8765079	intact:EBI-8765079	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8848247|imex:IM-21414-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	-	-	-	figure legend:"Fig. 5b (lower panel)"|comment:"The estimated molecular weight of the WT of the filtered product corresponds roughly to a hexameric conformation (210 kD).   This double mutant elutes at roughly the size of a trimer (120 kD) and dimer (70 kD)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	intact-crc:3667E2776C2D0FE1|rigid:CJyJa9LocLlPcPbDQFu+PtlftNs	false	sufficient binding region:38-318|mutation:227-227,291-291	sufficient binding region:38-318|mutation:227-227,291-291	3	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P75830	uniprotkb:P75830	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765117|imex:IM-21414-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	-	-	-	figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	intact-crc:D88D4E521EF384AC|rigid:YOAhxB9NB9Pl8YTzMERvLmCjAOg	false	sufficient binding region:32-371	sufficient binding region:32-371	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AE06	uniprotkb:P0AE06	intact:EBI-875601|uniprotkb:P31223|uniprotkb:Q2MBW4|ensemblbacteria:AAC73565|ensemblbacteria:BAE76242	intact:EBI-875601|uniprotkb:P31223|uniprotkb:Q2MBW4|ensemblbacteria:AAC73565|ensemblbacteria:BAE76242	psi-mi:acra_ecoli(display_long)|uniprotkb:acrA(gene name)|psi-mi:acrA(display_short)|uniprotkb:lir(gene name synonym)|uniprotkb:mtcA(gene name synonym)|uniprotkb:b0463(locus name)|uniprotkb:JW0452(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrA(gene name synonym)|uniprotkb:Acridine resistance protein A(gene name synonym)	psi-mi:acra_ecoli(display_long)|uniprotkb:acrA(gene name)|psi-mi:acrA(display_short)|uniprotkb:lir(gene name synonym)|uniprotkb:mtcA(gene name synonym)|uniprotkb:b0463(locus name)|uniprotkb:JW0452(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrA(gene name synonym)|uniprotkb:Acridine resistance protein A(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765120|imex:IM-21414-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414996.1|refseq:WP_001295324.1|dip:DIP-29039N|ensemblbacteria:AAC73565(transcript)|ensemblbacteria:b0463(gene)|ensemblbacteria:BAE76242(gene)|ensemblbacteria:BAE76242(transcript)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990281"(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:2F1M|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S	refseq:NP_414996.1|refseq:WP_001295324.1|dip:DIP-29039N|ensemblbacteria:AAC73565(transcript)|ensemblbacteria:b0463(gene)|ensemblbacteria:BAE76242(gene)|ensemblbacteria:BAE76242(transcript)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990281"(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:2F1M|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S	-	crc64:5B81DD5BC2B0A077	crc64:5B81DD5BC2B0A077	figure legend:Fig. 4a|comment:The authors do not give the length of this construct while the other proteins were all expressed as slightly truncated versions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:SAeFuPoeyyXFuBiQN5ZAQH5f5W883333	rogid:SAeFuPoeyyXFuBiQN5ZAQH5f5W883333	intact-crc:F7FE13E0CF29D030|rigid:KiltC+lzX9A7t+9ldXTu9Mj2/F0	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2EHL9	uniprotkb:Q2EHL9	intact:EBI-8765079	intact:EBI-8765079	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:q2ehl9_aggac(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)	psi-mi:"MI:0040"(electron microscopy)	Yum et al. (2009)	pubmed:19254725|imex:IM-21414	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	taxid:714(aggac)|taxid:714(Aggregatibacter actinomycetemcomitans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765100|imex:IM-21414-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR006143(Secretion protein HlyD)|rcsb pdb:4DK0|interpro:IPR032317|rcsb pdb:4DK1|refseq:WP_025298383.1	-	-	-	figure legend:Fig. 4b, S5, S7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/17	2014/10/16	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	rogid:eSlEFHV4bbMaT4jYxnCOY8Frpfk714	intact-crc:AC07B77DB6D28B1C|rigid:CJyJa9LocLlPcPbDQFu+PtlftNs	false	sufficient binding region:38-318	sufficient binding region:38-318	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)