#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9XVI2 uniprotkb:Q10666 intact:EBI-3871339|ensemblmetazoa:T23D8.9a.1|ensemblmetazoa:T23D8.9a.2 intact:EBI-317870|uniprotkb:O45007|ensemblmetazoa:W10C8.2.1 psi-mi:q9xvi2_caeel(display_long)|uniprotkb:sys-1(gene name)|psi-mi:sys-1(display_short)|uniprotkb:T23D8.9(orf name)|uniprotkb:CELE_T23D8.9(orf name) psi-mi:pop1_caeel(display_long)|uniprotkb:pop-1(gene name)|psi-mi:pop-1(display_short)|uniprotkb:W10C8.2(orf name)|uniprotkb:Posterior pharynx defect protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Liu et al. (2008) pubmed:18477457|imex:IM-21059 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6919455|imex:IM-21059-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492639.1|wormbase:T23D8.9a|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:3C2G|rcsb pdb:3C2H|ensemblmetazoa:T23D8.9a.1(transcript)|ensemblmetazoa:T23D8.9a.2(transcript)|ensemblmetazoa:WBGene00006379(gene)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008406"(gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0008584"(male gonad development) reactome:R-CEL-4641265|wormbase:W10C8.2|reactome:R-CEL-8853884|reactome:R-CEL-3769402|refseq:NP_491053.4|ensemblmetazoa:W10C8.2.1(transcript)|ensemblmetazoa:WBGene00004077(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061853"(regulation of neuroblast migration)|go:"GO:2000746"(regulation of defecation rhythm)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|interpro:IPR028782|interpro:IPR036910|rcsb pdb:3C2G|go:"GO:1990907"(beta-catenin-TCF complex)|dip:DIP-25683N|reactome:R-CEL-201722|reactome:R-CEL-4086398|reactome:R-CEL-8951430 - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/08/06 2014/10/16 rogid:snnG1C51tuSIfFLY/PYXbRjQimo6239 rogid:kzktFe2ZSDObXvcMQsdR9o90wGI6239 intact-crc:A07729A308F73C59|rigid:/U808cd2Eal87UP/CTXWXUU0hhw false mutation disrupting interaction strength:539-539|mutation disrupting interaction strength:533-533|sufficient binding region:180-811 sufficient binding region:1-45|glutathione s tranferase tag:?-?|mutation disrupting interaction strength:9-9 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9XVI2 uniprotkb:Q10666 intact:EBI-3871339|ensemblmetazoa:T23D8.9a.1|ensemblmetazoa:T23D8.9a.2 intact:EBI-317870|uniprotkb:O45007|ensemblmetazoa:W10C8.2.1 psi-mi:q9xvi2_caeel(display_long)|uniprotkb:sys-1(gene name)|psi-mi:sys-1(display_short)|uniprotkb:T23D8.9(orf name)|uniprotkb:CELE_T23D8.9(orf name) psi-mi:pop1_caeel(display_long)|uniprotkb:pop-1(gene name)|psi-mi:pop-1(display_short)|uniprotkb:W10C8.2(orf name)|uniprotkb:Posterior pharynx defect protein 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Liu et al. (2008) pubmed:18477457|imex:IM-21059 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-6919584|imex:IM-21059-2|pdbe:3c2g - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492639.1|wormbase:T23D8.9a|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:3C2G|rcsb pdb:3C2H|ensemblmetazoa:T23D8.9a.1(transcript)|ensemblmetazoa:T23D8.9a.2(transcript)|ensemblmetazoa:WBGene00006379(gene)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008406"(gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0008584"(male gonad development)|pdbe:3c2h reactome:R-CEL-4641265|wormbase:W10C8.2|reactome:R-CEL-8853884|reactome:R-CEL-3769402|refseq:NP_491053.4|ensemblmetazoa:W10C8.2.1(transcript)|ensemblmetazoa:WBGene00004077(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061853"(regulation of neuroblast migration)|go:"GO:2000746"(regulation of defecation rhythm)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|interpro:IPR028782|interpro:IPR036910|rcsb pdb:3C2G|go:"GO:1990907"(beta-catenin-TCF complex)|dip:DIP-25683N|reactome:R-CEL-201722|reactome:R-CEL-4086398|reactome:R-CEL-8951430 - - - figure legend:Table 1|3d-resolution:2.5A|3d-r-factors:Rfree=26.1%, Rwork=21.6%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/08/06 2014/10/16 rogid:snnG1C51tuSIfFLY/PYXbRjQimo6239 rogid:kzktFe2ZSDObXvcMQsdR9o90wGI6239 intact-crc:530D34D4394E77D7|rigid:/U808cd2Eal87UP/CTXWXUU0hhw false sufficient binding region:180-798 sufficient binding region:8-15 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)