#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6XLQ0	uniprotkb:Q90ZH5	intact:EBI-6663486|ensembl:ENSGALP00000058796	intact:EBI-6663469	psi-mi:q6xlq0_chick(display_long)|uniprotkb:hairy1(gene name)|psi-mi:hairy1(display_short)|uniprotkb:HES4(gene name synonym)	psi-mi:q90zh5_chick(display_long)|uniprotkb:chSAP18(gene name)|psi-mi:chSAP18(display_short)	psi-mi:"MI:0018"(two hybrid)	Sheeba et al. (2007)	pubmed:17623094|imex:IM-25936	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6671545|imex:IM-25936-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSGALG00000002055(gene)|ensembl:ENSGALT00000085574(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060173"(limb development)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001005848.1	go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR042534|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR010516(Sin3 associated polypeptide p18)|refseq:NP_989643.1	go:"GO:0004565"(beta-galactosidase activity)	-	-	comment:Hairy1 associate with Sap18 through the C-terminal domain|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/03	2014/10/16	rogid:Y4h/+819RPYGvdOtYBhsIBK/PcU9031	rogid:/AkXOVTwHva41C7WFHkqiOGGLjQ9031	intact-crc:B242A0139D72D465|rigid:ghFnjX41pFHcjLm/KuMzL6+f25I	false	necessary binding region:150-290	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6XLQ0	uniprotkb:Q6XLQ0	intact:EBI-6663486|ensembl:ENSGALP00000058796	intact:EBI-6663486|ensembl:ENSGALP00000058796	psi-mi:q6xlq0_chick(display_long)|uniprotkb:hairy1(gene name)|psi-mi:hairy1(display_short)|uniprotkb:HES4(gene name synonym)	psi-mi:q6xlq0_chick(display_long)|uniprotkb:hairy1(gene name)|psi-mi:hairy1(display_short)|uniprotkb:HES4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sheeba et al. (2007)	pubmed:17623094|imex:IM-25936	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6663453|imex:IM-25936-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSGALG00000002055(gene)|ensembl:ENSGALT00000085574(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060173"(limb development)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001005848.1	ensembl:ENSGALG00000002055(gene)|ensembl:ENSGALT00000085574(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060173"(limb development)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001005848.1	go:"GO:0004565"(beta-galactosidase activity)	-	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/03	2014/10/16	rogid:Y4h/+819RPYGvdOtYBhsIBK/PcU9031	rogid:Y4h/+819RPYGvdOtYBhsIBK/PcU9031	intact-crc:644301ED10F8A6E8|rigid:379sPPpJeQj44RraZib09jGaehM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q90ZH5	uniprotkb:Q6XLQ0	intact:EBI-6663469	intact:EBI-6663486|ensembl:ENSGALP00000058796	psi-mi:q90zh5_chick(display_long)|uniprotkb:chSAP18(gene name)|psi-mi:chSAP18(display_short)	psi-mi:q6xlq0_chick(display_long)|uniprotkb:hairy1(gene name)|psi-mi:hairy1(display_short)|uniprotkb:HES4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sheeba et al. (2007)	pubmed:17623094|imex:IM-25936	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6663465|imex:IM-25936-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR042534|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR010516(Sin3 associated polypeptide p18)|refseq:NP_989643.1	ensembl:ENSGALG00000002055(gene)|ensembl:ENSGALT00000085574(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060173"(limb development)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001005848.1	go:"GO:0004565"(beta-galactosidase activity)	-	-	figure legend:2|comment:Hairy1 associate with Sap18 through the C-terminal domain|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/03	2014/10/16	rogid:/AkXOVTwHva41C7WFHkqiOGGLjQ9031	rogid:Y4h/+819RPYGvdOtYBhsIBK/PcU9031	intact-crc:AD944C874751CE46|rigid:ghFnjX41pFHcjLm/KuMzL6+f25I	false	-	necessary binding region:150-290	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q90ZH5	uniprotkb:Q6XLQ0	intact:EBI-6663469	intact:EBI-6663486|ensembl:ENSGALP00000058796	psi-mi:q90zh5_chick(display_long)|uniprotkb:chSAP18(gene name)|psi-mi:chSAP18(display_short)	psi-mi:q6xlq0_chick(display_long)|uniprotkb:hairy1(gene name)|psi-mi:hairy1(display_short)|uniprotkb:HES4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sheeba et al. (2007)	pubmed:17623094|imex:IM-25936	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6671523|imex:IM-25936-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR042534|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR010516(Sin3 associated polypeptide p18)|refseq:NP_989643.1	ensembl:ENSGALG00000002055(gene)|ensembl:ENSGALT00000085574(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060173"(limb development)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001005848.1	-	-	-	figure legend:3|comment:Chick hairy1 and sap18 genes  cloned in pGBKT7 and pGADT7 vectors, respectively, were used to generate 35S-labeled c-Myc-Hairy1 and HASap18  through in vitro transcription/translation reactions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/03	2014/10/16	rogid:/AkXOVTwHva41C7WFHkqiOGGLjQ9031	rogid:Y4h/+819RPYGvdOtYBhsIBK/PcU9031	intact-crc:D371F9D23C03D31C|rigid:ghFnjX41pFHcjLm/KuMzL6+f25I	false	ha tag:?-?|35s radiolabel:?-?	myc tag:?-?|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q90ZH5	uniprotkb:Q6XLQ0	intact:EBI-6663469	intact:EBI-6663486|ensembl:ENSGALP00000058796	psi-mi:q90zh5_chick(display_long)|uniprotkb:chSAP18(gene name)|psi-mi:chSAP18(display_short)	psi-mi:q6xlq0_chick(display_long)|uniprotkb:hairy1(gene name)|psi-mi:hairy1(display_short)|uniprotkb:HES4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sheeba et al. (2007)	pubmed:17623094|imex:IM-25936	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6663523|imex:IM-25936-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR042534|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR010516(Sin3 associated polypeptide p18)|refseq:NP_989643.1	ensembl:ENSGALG00000002055(gene)|ensembl:ENSGALT00000085574(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001756"(somitogenesis)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060173"(limb development)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001005848.1	-	-	-	figure legend:3|comment:Chick hairy1 and sap18 genes  cloned in pGBKT7 and pGADT7 vectors, respectively, were used to generate 35S-labeled c-Myc-Hairy1 and HASap18  through in vitro transcription/translation reactions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/03	2014/10/16	rogid:/AkXOVTwHva41C7WFHkqiOGGLjQ9031	rogid:Y4h/+819RPYGvdOtYBhsIBK/PcU9031	intact-crc:3AF84B78886C091A|rigid:ghFnjX41pFHcjLm/KuMzL6+f25I	false	35s radiolabel:?-?|ha tag:?-?	35s radiolabel:?-?|myc tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)