#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q58A45	uniprotkb:P11940	intact:EBI-2513054|uniprotkb:B7Z3W7|ensembl:ENSP00000370345|uniprotkb:Q76E13|uniprotkb:Q8NBA6|uniprotkb:A1A4Y9|uniprotkb:Q5T515|uniprotkb:Q5T516|uniprotkb:Q5HYG6|uniprotkb:Q5TBA0|uniprotkb:B1ALF1|uniprotkb:A0N0X1|uniprotkb:A1A4Y8|uniprotkb:Q0D2P2	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:pan3_human(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8805560|imex:IM-21755-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152520(gene)|ensembl:ENST00000380958(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0031251"(PAN complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR030844|interpro:IPR036855|interpro:IPR041332|reactome:R-HSA-429947|mint:Q58A45|refseq:NP_787050.6|ensembl:ENSP00000370345|refseq:XP_005266390.1|refseq:XP_005266391.1|refseq:XP_016876021.1|refseq:XP_016876022.1|dip:DIP-53755N	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	-	-	-	figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/22	2014/10/16	rogid:mwXI4k9hdjdxaPRQ9UXH7pC7nuQ9606	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:E0A9479949039DC4|rigid:oPv5ngr5Nbs7+CYYoKQeU5cKpw4	false	35s radiolabel:?-?|mutation decreasing interaction:293-293	glutathione s tranferase tag:?-?|sufficient binding region:498-636(IPR002004)	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P11940	uniprotkb:O95453	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	intact:EBI-372832|uniprotkb:B2RCB3|ensembl:ENSP00000387911|ensembl:ENSP00000478668|intact:EBI-28988750|uniprotkb:B4DSB0|uniprotkb:B4DDG8|uniprotkb:B4DWR4|uniprotkb:B4E1H6	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:parn_human(display_long)|uniprotkb:PARN(gene name)|psi-mi:PARN(display_short)|uniprotkb:Polyadenylate-specific ribonuclease(gene name synonym)|uniprotkb:Deadenylating nuclease(gene name synonym)|uniprotkb:Deadenylation nuclease(gene name synonym)|uniprotkb:DAN(gene name synonym)	psi-mi:"MI:0096"(pull down)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8805787|imex:IM-21755-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	refseq:NP_002573.1|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:0110008"(ncRNA deadenylation)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014789("Poly(A)-specific ribonuclease, RNA binding")|interpro:IPR034042|interpro:IPR035979|interpro:IPR036397|interpro:IPR036867|mint:O95453|rcsb pdb:2A1R|rcsb pdb:2A1S|rcsb pdb:3CTR|reactome:R-HSA-380994|reactome:R-HSA-429947|reactome:R-HSA-450604|ensembl:ENSG00000140694(gene)|ensembl:ENSG00000274829(gene)|ensembl:ENST00000437198(transcript)|ensembl:ENST00000615183(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007292"(female gamete generation)|go:"GO:0009451"(RNA modification)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043169"(cation binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|refseq:NP_001127949.1|refseq:NP_001229921.1|ensembl:ENST00000341484|ensembl:ENSP00000345456|ensembl:ENST00000420015|ensembl:ENSP00000410525|ensembl:ENSP00000387911|ensembl:ENST00000539279|ensembl:ENSP00000444381|ensembl:ENSP00000478668|ensembl:ENST00000618929|ensembl:ENSP00000484279|ensembl:ENST00000631868|ensembl:ENSP00000488554|ensembl:ENST00000634004|ensembl:ENSP00000487634|dip:DIP-31124N	-	-	-	figure legend:Fig. 4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/22	2014/10/16	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:V/6onCtb7dz2cK4pEHQwvHqEFuQ9606	intact-crc:0C4F004A958B67D6|rigid:P/fetZEZBwm0R+kJEPBnRSlJi8k	false	glutathione s tranferase tag:?-?|necessary binding region:1-497	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P11940	uniprotkb:Q58A45	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	intact:EBI-2513054|uniprotkb:B7Z3W7|ensembl:ENSP00000370345|uniprotkb:Q76E13|uniprotkb:Q8NBA6|uniprotkb:A1A4Y9|uniprotkb:Q5T515|uniprotkb:Q5T516|uniprotkb:Q5HYG6|uniprotkb:Q5TBA0|uniprotkb:B1ALF1|uniprotkb:A0N0X1|uniprotkb:A1A4Y8|uniprotkb:Q0D2P2	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:pan3_human(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8817453|imex:IM-21755-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	ensembl:ENSG00000152520(gene)|ensembl:ENST00000380958(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0031251"(PAN complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR030844|interpro:IPR036855|interpro:IPR041332|reactome:R-HSA-429947|mint:Q58A45|refseq:NP_787050.6|ensembl:ENSP00000370345|refseq:XP_005266390.1|refseq:XP_005266391.1|refseq:XP_016876021.1|refseq:XP_016876022.1|dip:DIP-53755N	-	-	-	figure legend:Fig. 2a|kinetic_conditions:Temp = 15C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:40.0x10^-6(molar)	2013/10/22	2014/10/16	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:mwXI4k9hdjdxaPRQ9UXH7pC7nuQ9606	intact-crc:6081112F4AAD54E0|rigid:oPv5ngr5Nbs7+CYYoKQeU5cKpw4	false	sufficient binding region:544-636(IPR002004)	sufficient binding region:284-300(LIG_PAM2_1)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04147	uniprotkb:P36102	intact:EBI-12823|ensemblfungi:YER165W|uniprotkb:D3DM73	intact:EBI-12895|ensemblfungi:YKL025C|uniprotkb:D6VXQ9	psi-mi:pabp_yeast(display_long)|uniprotkb:PAB1(gene name)|psi-mi:PAB1(display_short)|uniprotkb:ARS consensus-binding protein ACBP-67(gene name synonym)|uniprotkb:Polyadenylate tail-binding protein(gene name synonym)|uniprotkb:YER165W(locus name)	psi-mi:pan3_yeast(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:ECM35(gene name synonym)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)|uniprotkb:YKL025C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8817605|imex:IM-21755-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER165W(gene)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008143"("poly(A) binding")|ensemblfungi:YER165W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|rcsb pdb:1IFW|rcsb pdb:6R5K|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-156827|refseq:NP_011092.1|sgd:S000000967|mint:P04147|dip:DIP-2275N	ensemblfungi:YKL025C(gene)|go:"GO:0031251"(PAN complex)|ensemblfungi:YKL025C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|go:"GO:0003723"(RNA binding)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|interpro:IPR030844|interpro:IPR041332|rcsb pdb:4CYK|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4XR7|reactome:R-SCE-429947|go:"GO:0008143"("poly(A) binding")|refseq:NP_012900.1|sgd:S000001508|mint:P36102|dip:DIP-3987N	-	crc64:4F97E494753E17C7	crc64:DE03E15BF4A5DA7C	figure legend:Fig 5a|kinetic_conditions:Temp = 15C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:165.0x10^-6(molar)	2013/10/22	2014/10/16	rogid:6ZjESO1CUgykLdGVlTuZoFRwqyg559292	rogid:3WaNQ0kDMX1U4WAAWP2StsyyjGU559292	intact-crc:1EAA1C05E44131EB|rigid:2WW8l9LxFl+BtnSduusSb/SSZ/4	false	sufficient binding region:491-577(IPR002004)	sufficient binding region:146-161	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36102	uniprotkb:P04147	intact:EBI-12895|ensemblfungi:YKL025C|uniprotkb:D6VXQ9	intact:EBI-12823|ensemblfungi:YER165W|uniprotkb:D3DM73	psi-mi:pan3_yeast(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:ECM35(gene name synonym)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)|uniprotkb:YKL025C(locus name)	psi-mi:pabp_yeast(display_long)|uniprotkb:PAB1(gene name)|psi-mi:PAB1(display_short)|uniprotkb:ARS consensus-binding protein ACBP-67(gene name synonym)|uniprotkb:Polyadenylate tail-binding protein(gene name synonym)|uniprotkb:YER165W(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9003914|imex:IM-21755-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL025C(gene)|go:"GO:0031251"(PAN complex)|ensemblfungi:YKL025C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|go:"GO:0003723"(RNA binding)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|interpro:IPR030844|interpro:IPR041332|rcsb pdb:4CYK|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4XR7|reactome:R-SCE-429947|go:"GO:0008143"("poly(A) binding")|refseq:NP_012900.1|sgd:S000001508|mint:P36102|dip:DIP-3987N	ensemblfungi:YER165W(gene)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008143"("poly(A) binding")|ensemblfungi:YER165W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|rcsb pdb:1IFW|rcsb pdb:6R5K|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-156827|refseq:NP_011092.1|sgd:S000000967|mint:P04147|dip:DIP-2275N	-	crc64:DE03E15BF4A5DA7C	crc64:4F97E494753E17C7	figure legend:Fig. 5a|kinetic_conditions:Temp = 15C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:150.0x10^-6(molar)	2013/10/22	2014/10/16	rogid:3WaNQ0kDMX1U4WAAWP2StsyyjGU559292	rogid:6ZjESO1CUgykLdGVlTuZoFRwqyg559292	intact-crc:7A191582E3DFB642|rigid:2WW8l9LxFl+BtnSduusSb/SSZ/4	false	sufficient binding region:138-162	sufficient binding region:491-577(IPR002004)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11940	uniprotkb:Q58A45	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	intact:EBI-2513054|uniprotkb:B7Z3W7|ensembl:ENSP00000370345|uniprotkb:Q76E13|uniprotkb:Q8NBA6|uniprotkb:A1A4Y9|uniprotkb:Q5T515|uniprotkb:Q5T516|uniprotkb:Q5HYG6|uniprotkb:Q5TBA0|uniprotkb:B1ALF1|uniprotkb:A0N0X1|uniprotkb:A1A4Y8|uniprotkb:Q0D2P2	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:pan3_human(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8817528|imex:IM-21755-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	ensembl:ENSG00000152520(gene)|ensembl:ENST00000380958(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0031251"(PAN complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR030844|interpro:IPR036855|interpro:IPR041332|reactome:R-HSA-429947|mint:Q58A45|refseq:NP_787050.6|ensembl:ENSP00000370345|refseq:XP_005266390.1|refseq:XP_005266391.1|refseq:XP_016876021.1|refseq:XP_016876022.1|dip:DIP-53755N	-	-	-	figure legend:Fig. 2b, Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/22	2014/10/16	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	rogid:mwXI4k9hdjdxaPRQ9UXH7pC7nuQ9606	intact-crc:E68EF8A8C4D20D01|rigid:oPv5ngr5Nbs7+CYYoKQeU5cKpw4	false	15n label:?-?|sufficient binding region:498-636(IPR002004)	sufficient binding region:284-300(LIG_PAM2_1)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36102	uniprotkb:P04147	intact:EBI-12895|ensemblfungi:YKL025C|uniprotkb:D6VXQ9	intact:EBI-12823|ensemblfungi:YER165W|uniprotkb:D3DM73	psi-mi:pan3_yeast(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:ECM35(gene name synonym)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)|uniprotkb:YKL025C(locus name)	psi-mi:pabp_yeast(display_long)|uniprotkb:PAB1(gene name)|psi-mi:PAB1(display_short)|uniprotkb:ARS consensus-binding protein ACBP-67(gene name synonym)|uniprotkb:Polyadenylate tail-binding protein(gene name synonym)|uniprotkb:YER165W(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8817647|imex:IM-21755-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL025C(gene)|go:"GO:0031251"(PAN complex)|ensemblfungi:YKL025C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|go:"GO:0003723"(RNA binding)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|interpro:IPR030844|interpro:IPR041332|rcsb pdb:4CYK|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4XR7|reactome:R-SCE-429947|go:"GO:0008143"("poly(A) binding")|refseq:NP_012900.1|sgd:S000001508|mint:P36102|dip:DIP-3987N	ensemblfungi:YER165W(gene)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008143"("poly(A) binding")|ensemblfungi:YER165W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|rcsb pdb:1IFW|rcsb pdb:6R5K|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-156827|refseq:NP_011092.1|sgd:S000000967|mint:P04147|dip:DIP-2275N	-	crc64:DE03E15BF4A5DA7C	crc64:4F97E494753E17C7	figure legend:Fig. 3b, Fig. 5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/22	2014/10/16	rogid:3WaNQ0kDMX1U4WAAWP2StsyyjGU559292	rogid:6ZjESO1CUgykLdGVlTuZoFRwqyg559292	intact-crc:76863B9B8EF8A7A4|rigid:2WW8l9LxFl+BtnSduusSb/SSZ/4	false	sufficient binding region:146-161	sufficient binding region:491-577(IPR002004)|15n label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04147	uniprotkb:P36102	intact:EBI-12823|ensemblfungi:YER165W|uniprotkb:D3DM73	intact:EBI-12895|ensemblfungi:YKL025C|uniprotkb:D6VXQ9	psi-mi:pabp_yeast(display_long)|uniprotkb:PAB1(gene name)|psi-mi:PAB1(display_short)|uniprotkb:ARS consensus-binding protein ACBP-67(gene name synonym)|uniprotkb:Polyadenylate tail-binding protein(gene name synonym)|uniprotkb:YER165W(locus name)	psi-mi:pan3_yeast(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:ECM35(gene name synonym)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)|uniprotkb:YKL025C(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8817674|imex:IM-21755-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER165W(gene)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008143"("poly(A) binding")|ensemblfungi:YER165W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|rcsb pdb:1IFW|rcsb pdb:6R5K|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-156827|refseq:NP_011092.1|sgd:S000000967|mint:P04147|dip:DIP-2275N	ensemblfungi:YKL025C(gene)|go:"GO:0031251"(PAN complex)|ensemblfungi:YKL025C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|go:"GO:0003723"(RNA binding)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|interpro:IPR030844|interpro:IPR041332|rcsb pdb:4CYK|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4XR7|reactome:R-SCE-429947|go:"GO:0008143"("poly(A) binding")|refseq:NP_012900.1|sgd:S000001508|mint:P36102|dip:DIP-3987N	-	crc64:4F97E494753E17C7	crc64:DE03E15BF4A5DA7C	figure legend:Fig 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/22	2014/10/16	rogid:6ZjESO1CUgykLdGVlTuZoFRwqyg559292	rogid:3WaNQ0kDMX1U4WAAWP2StsyyjGU559292	intact-crc:504A40D21FB876C8|rigid:2WW8l9LxFl+BtnSduusSb/SSZ/4	false	sufficient binding region:491-577(IPR002004)	15n label:?-?|sufficient binding region:138-162	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04147	uniprotkb:P36102	intact:EBI-12823|ensemblfungi:YER165W|uniprotkb:D3DM73	intact:EBI-12895|ensemblfungi:YKL025C|uniprotkb:D6VXQ9	psi-mi:pabp_yeast(display_long)|uniprotkb:PAB1(gene name)|psi-mi:PAB1(display_short)|uniprotkb:ARS consensus-binding protein ACBP-67(gene name synonym)|uniprotkb:Polyadenylate tail-binding protein(gene name synonym)|uniprotkb:YER165W(locus name)	psi-mi:pan3_yeast(display_long)|uniprotkb:PAN3(gene name)|psi-mi:PAN3(display_short)|uniprotkb:ECM35(gene name synonym)|uniprotkb:"PAB1P-dependent poly(A)-specific ribonuclease"(gene name synonym)|uniprotkb:"Poly(A)-nuclease deadenylation complex subunit 3"(gene name synonym)|uniprotkb:YKL025C(locus name)	psi-mi:"MI:0018"(two hybrid)	Siddiqui et al. (2007)	pubmed:17595167|imex:IM-21755	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8817782|imex:IM-21755-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER165W(gene)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008143"("poly(A) binding")|ensemblfungi:YER165W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|rcsb pdb:1IFW|rcsb pdb:6R5K|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-156827|refseq:NP_011092.1|sgd:S000000967|mint:P04147|dip:DIP-2275N	ensemblfungi:YKL025C(gene)|go:"GO:0031251"(PAN complex)|ensemblfungi:YKL025C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR000719(Protein kinase, core)|go:"GO:0003723"(RNA binding)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|interpro:IPR030844|interpro:IPR041332|rcsb pdb:4CYK|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4XR7|reactome:R-SCE-429947|go:"GO:0008143"("poly(A) binding")|refseq:NP_012900.1|sgd:S000001508|mint:P36102|dip:DIP-3987N	-	crc64:4F97E494753E17C7	crc64:DE03E15BF4A5DA7C	figure legend:Fig. 7a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(baker's yeast-l40)|taxid:4932(Saccharomyces cerevisiae)	-	2013/10/22	2014/10/16	rogid:6ZjESO1CUgykLdGVlTuZoFRwqyg559292	rogid:3WaNQ0kDMX1U4WAAWP2StsyyjGU559292	intact-crc:B903EE2488F54BAF|rigid:2WW8l9LxFl+BtnSduusSb/SSZ/4	false	sufficient binding region:406-577(IPR002004)	mutation decreasing interaction:151-151|mutation decreasing interaction:152-152|mutation decreasing interaction:156-156|mutation decreasing interaction:151-151,156-156	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)