#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P17888	uniprotkb:P07013	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556121|imex:IM-18706-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	-	-	-	figure legend:Fig. 2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.2x10^-7(molar)	2013/03/07	2014/10/16	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:A0031309AB80CB8B|rigid:Kd7b1OfQNATd2WUJ2VbQQ3pPLtM	false	his tag:n-n|sufficient binding region:199-732	fluorescein isothiocyanate label:?-?|his tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0A8J2	uniprotkb:P17888	intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym)	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556469|imex:IM-18706-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	go:"GO:0003697"(single-stranded DNA binding)	crc64:8DE048A3B2A6235B	-	figure legend:Fig. 5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/07	2020/01/31	rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	intact-crc:F388265FBD02ECBC	false	his tag:n-n|fluorescein isothiocyanate label:?-?	his tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0A8J2	uniprotkb:P07013	intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556469|imex:IM-18706-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	go:"GO:0003697"(single-stranded DNA binding)	crc64:8DE048A3B2A6235B	-	figure legend:Fig. 5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/07	2020/01/31	rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:F388265FBD02ECBC	false	his tag:n-n|fluorescein isothiocyanate label:?-?	mutation decreasing interaction:44-44|mutation decreasing interaction:39-39|his tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0A8J2	intact:EBI-6508950	intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352	chebi:"CHEBI:9160"	psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym)	psi-mi:ssdna-1(display_short)|psi-mi:EBI-6508950(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556469|imex:IM-18706-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7	-	go:"GO:0003697"(single-stranded DNA binding)	crc64:8DE048A3B2A6235B	-	figure legend:Fig. 5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/07	2020/01/31	rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333	-	intact-crc:F388265FBD02ECBC	false	his tag:n-n|fluorescein isothiocyanate label:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07013	intact:EBI-6508950	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	chebi:"CHEBI:9160"	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:ssdna-1(display_short)|psi-mi:EBI-6508950(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556209|imex:IM-18706-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	-	go:"GO:0003697"(single-stranded DNA binding)	-	-	figure legend:Fig. 2c, Tab. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.4x10^-8(molar)	2013/03/07	2020/01/31	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	-	intact-crc:2862AEE86198D69B	false	mutation decreasing interaction:44-44|mutation decreasing interaction:82-82|his tag:n-n|mutation decreasing interaction:47-47,82-82	fluorescein label:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P17888	uniprotkb:P07013	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6555996|imex:IM-18706-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	go:"GO:0003697"(single-stranded DNA binding)	-	-	figure legend:Fig. 2a, Tab. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.6x10^-8(molar)	2013/03/07	2020/01/31	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:2EB008832B984E8F	false	his tag:n-n	his tag:n-n|fluorescein isothiocyanate label:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P17888	intact:EBI-6508950	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	chebi:"CHEBI:9160"	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:ssdna-1(display_short)|psi-mi:EBI-6508950(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6555996|imex:IM-18706-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	-	go:"GO:0003697"(single-stranded DNA binding)	-	-	figure legend:Fig. 2a, Tab. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.6x10^-8(molar)	2013/03/07	2020/01/31	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	-	intact-crc:2EB008832B984E8F	false	his tag:n-n	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0A8J2	uniprotkb:P07013	intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556434|imex:IM-18706-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	go:"GO:0003697"(single-stranded DNA binding)	crc64:8DE048A3B2A6235B	-	figure legend:Fig. 3b, Tab. 1|comment:PriB has a higher affinity for DnaT than ssDNA. Therefore, DnaT displaced PriB from ssDNA and bound to it reducing the anisotrophy of labelled ssDNA. If DnaT fails to bind a PriB mutant, the PriB mutant remains bound to the ssDNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-7(molar)	2013/03/07	2020/01/31	rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:8DF92832A2B6A205	false	his tag:n-n	mutation decreasing interaction:84-84|mutation decreasing interaction:47-47,82-82|his tag:n-n|mutation decreasing interaction:89-89|mutation decreasing interaction:44-44|mutation decreasing interaction:82-82|mutation decreasing interaction:42-42|mutation decreasing interaction:39-39|mutation decreasing interaction:47-47	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0A8J2	intact:EBI-6508950	intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352	chebi:"CHEBI:9160"	psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym)	psi-mi:ssdna-1(display_short)|psi-mi:EBI-6508950(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556434|imex:IM-18706-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7	-	go:"GO:0003697"(single-stranded DNA binding)	crc64:8DE048A3B2A6235B	-	figure legend:Fig. 3b, Tab. 1|comment:PriB has a higher affinity for DnaT than ssDNA. Therefore, DnaT displaced PriB from ssDNA and bound to it reducing the anisotrophy of labelled ssDNA. If DnaT fails to bind a PriB mutant, the PriB mutant remains bound to the ssDNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.5x10^-7(molar)	2013/03/07	2020/01/31	rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333	-	intact-crc:8DF92832A2B6A205	false	his tag:n-n	fluorescein label:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P0A8J2	uniprotkb:P07013	intact:EBI-549621|uniprotkb:P07904|uniprotkb:Q2M5V4|ensemblbacteria:AAC77318|ensemblbacteria:BAE78352	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:dnat_ecoli(display_long)|uniprotkb:dnaT(gene name)|psi-mi:dnaT(display_short)|uniprotkb:b4362(locus name)|uniprotkb:JW4326(locus name)|uniprotkb:Primosomal protein I(gene name synonym)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556273|imex:IM-18706-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418782.1|refseq:WP_000098818.1|dip:DIP-47957N|ensemblbacteria:AAC77318(transcript)|ensemblbacteria:b4362(gene)|ensemblbacteria:BAE78352(gene)|ensemblbacteria:BAE78352(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0042802"(identical protein binding)|go:"GO:1990077"(primosome complex)|interpro:IPR020917|interpro:IPR040480|rcsb pdb:2RU8|rcsb pdb:4OU6|rcsb pdb:4OU7	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	-	crc64:8DE048A3B2A6235B	-	figure legend:Fig. 3a, Tab 1|comment:While an increase in fluorescence anisotropy of FITC-DnaT following addition of PriB was observed, the interaction requires high concentrations of PriB and is not saturable, precluding KD,app determination. Thus, while a direct, physical interaction exists between PriB and DnaT, it needs additional factors.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/07	2014/10/16	rogid:Ca5J+AWjsjBGNNpTU2itH6zmSZc83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:8239A500447AF403|rigid:TErVPZg2hwV4Wi4A0I3n03HqXOk	false	fluorescein isothiocyanate label:?-?|his tag:n-n	mutation decreasing interaction:47-47,82-82|mutation increasing interaction:45-45|his tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P17888	uniprotkb:P07013	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556093|imex:IM-18706-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	go:"GO:0003697"(single-stranded DNA binding)	-	-	figure legend:Fig. 2b, Tab. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.2x10^-7(molar)	2013/03/07	2020/01/31	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:5E7E35CAAF0ACF0B	false	his tag:n-n	his tag:n-n|mutation decreasing interaction:44-44|mutation decreasing interaction:47-47,82-82|mutation decreasing interaction:39-39	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P17888	uniprotkb:P07013	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556093|imex:IM-18706-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	go:"GO:0003697"(single-stranded DNA binding)	-	-	figure legend:Fig. 2b, Tab. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.2x10^-7(molar)	2013/03/07	2020/01/31	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:5E7E35CAAF0ACF0B	false	his tag:n-n	fluorescein isothiocyanate label:?-?|his tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P17888	intact:EBI-6508950	intact:EBI-552050|uniprotkb:Q2M8N1|ensemblbacteria:AAC76917|ensemblbacteria:BAE77375	chebi:"CHEBI:9160"	psi-mi:pria_ecoli(display_long)|uniprotkb:priA(gene name)|psi-mi:priA(display_short)|uniprotkb:b3935(locus name)|uniprotkb:Replication factor Y(gene name synonym)|uniprotkb:JW3906(locus name)|uniprotkb:ATP-dependent helicase PriA(gene name synonym)	psi-mi:ssdna-1(display_short)|psi-mi:EBI-6508950(display_long)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556093|imex:IM-18706-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	refseq:NP_418370.1|refseq:WP_001301269.1|dip:DIP-10562N|ensemblbacteria:AAC76917(transcript)|ensemblbacteria:b3935(gene)|ensemblbacteria:BAE77375(gene)|ensemblbacteria:BAE77375(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990077"(primosome complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR005259(Primosomal protein n)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR040498|interpro:IPR041222|interpro:IPR041236|interpro:IPR042115|rcsb pdb:2D7E|rcsb pdb:2D7G|rcsb pdb:2D7H|rcsb pdb:2DWL|rcsb pdb:2DWM|rcsb pdb:2DWN|rcsb pdb:6DCR	-	go:"GO:0003697"(single-stranded DNA binding)	-	-	figure legend:Fig. 2b, Tab. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.2x10^-7(molar)	2013/03/07	2020/01/31	rogid:QD9LmjaQ1XsaW1D5sdGnrHTihgQ83333	-	intact-crc:5E7E35CAAF0ACF0B	false	his tag:n-n	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07013	uniprotkb:P07013	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	intact:EBI-1125223|uniprotkb:Q2M6A4|ensemblbacteria:AAC77158|ensemblbacteria:BAE78202	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:prib_ecoli(display_long)|uniprotkb:priB(gene name)|psi-mi:priB(display_short)|uniprotkb:b4201(locus name)|uniprotkb:JW4159(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Lopper et al. (2007)	imex:IM-18706|pubmed:17588514	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6556500|wwpdb:2pnh|imex:IM-18706-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	refseq:NP_418622.1|refseq:WP_001315977.1|ensemblbacteria:b4201(gene)|ensemblbacteria:BAE78202(gene)|ensemblbacteria:BAE78202(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006276"(plasmid maintenance)|go:"GO:0009314"(response to radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:1990099"(pre-primosome complex)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR023646|rcsb pdb:1TXY|rcsb pdb:1V1Q|rcsb pdb:1WOC|rcsb pdb:2CCZ|rcsb pdb:2PNH|rcsb pdb:5WQV|ensemblbacteria:AAC77158(transcript)|dip:DIP-10563N	-	-	-	figure legend:Fig. S2|3d-r-factors:Rwork = 0.25; Rfree = 0.28|3d-resolution:2.25A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/07	2014/10/16	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	rogid:t9m94Sm9Zz1cXCqAybm67nkDNRQ83333	intact-crc:073FE4991A91491C|rigid:tQEr3Esz+2lSYwSpvmxxeS+lDxU	false	his tag:n-n|mutation:39-39	his tag:n-n|mutation:39-39	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)