#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P61020 intact:EBI-8853273 intact:EBI-399401|uniprotkb:P35239|uniprotkb:P35277|uniprotkb:Q6PIK9|uniprotkb:Q86TH0|uniprotkb:Q8IXL2|uniprotkb:A8K982|uniprotkb:B4DKD7|ensembl:ENSP00000353444|ensembl:ENSP00000450168 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:rab5b_human(display_long)|uniprotkb:RAB5B(gene name)|psi-mi:RAB5B(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Stone et al. (2007) pubmed:17301141|imex:IM-25879 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-8853299|imex:IM-25879-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_002859.1|refseq:NP_001238965.1|refseq:XP_005269108.1|refseq:XP_005269109.1|refseq:NP_001238966.1|ensembl:ENSG00000111540(gene)|ensembl:ENST00000360299(transcript)|ensembl:ENST00000553116(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2HEI|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 go:"GO:0005769"(early endosome) chain-seq-start:1712|chain-seq-end:1972 - figure legend:Fig. 2D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2013/11/18 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:jm+x3SYDL+i+/BrDFnp44kxlHUM9606 intact-crc:6356E30133B51BCF|rigid:hmcVaz/jUdZ3NvgSCd44YQm5wK0 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9WMX2-PRO_0000037551 uniprotkb:P61020 intact:EBI-6863748 intact:EBI-399401|uniprotkb:P35239|uniprotkb:P35277|uniprotkb:Q6PIK9|uniprotkb:Q86TH0|uniprotkb:Q8IXL2|uniprotkb:A8K982|uniprotkb:B4DKD7|ensembl:ENSP00000353444|ensembl:ENSP00000450168 psi-mi:q9wmx2-pro_0000037551(display_long) psi-mi:rab5b_human(display_long)|uniprotkb:RAB5B(gene name)|psi-mi:RAB5B(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Stone et al. (2007) pubmed:17301141|imex:IM-25879 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-8853290|imex:IM-25879-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_002859.1|refseq:NP_001238965.1|refseq:XP_005269108.1|refseq:XP_005269109.1|refseq:NP_001238966.1|ensembl:ENSG00000111540(gene)|ensembl:ENST00000360299(transcript)|ensembl:ENST00000553116(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2HEI|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 go:"GO:0005769"(early endosome) chain-seq-start:1973|chain-seq-end:2419 - figure legend:Fig. 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2013/11/18 2017/09/02 rogid:dkkgGI4Apbz9im+o4Uqn8t9r8kw333284 rogid:jm+x3SYDL+i+/BrDFnp44kxlHUM9606 intact-crc:4DF653B1F3B2EEC3|rigid:A9GNOW2uLVJQXT5e3+peXvD3Y6o false green fluorescent protein tag:?-? - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q9WMX2-PRO_0000037551 intact:EBI-8853273 intact:EBI-6863748 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:q9wmx2-pro_0000037551(display_long) psi-mi:"MI:0416"(fluorescence microscopy) Stone et al. (2007) pubmed:17301141|imex:IM-25879 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-8853267|imex:IM-25879-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) intact:EBI-710918(chain-parent) - chain-seq-start:1712|chain-seq-end:1972 chain-seq-start:1973|chain-seq-end:2419 figure legend:Fig. 1A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2013/11/18 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:dkkgGI4Apbz9im+o4Uqn8t9r8kw333284 intact-crc:F25D0854E9F2B0C6|rigid:reZOtC0OlJETb39e7SYVteXG7r8 false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q9WMX2-PRO_0000037551 intact:EBI-8853273 intact:EBI-6863748 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:q9wmx2-pro_0000037551(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stone et al. (2007) pubmed:17301141|imex:IM-25879 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9005424|imex:IM-25879-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) intact:EBI-710918(chain-parent) - chain-seq-start:1712|chain-seq-end:1972 chain-seq-start:1973|chain-seq-end:2419 figure legend:Fig. 5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/11/18 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:dkkgGI4Apbz9im+o4Uqn8t9r8kw333284 intact-crc:65214C614980EA35|rigid:gz0CcmML2+WIeLDCmRaa13QGpnw false - green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:P27824 intact:EBI-8853273 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stone et al. (2007) pubmed:17301141|imex:IM-25879 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9005424|imex:IM-25879-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Fig. 5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/11/18 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 intact-crc:65214C614980EA35|rigid:gz0CcmML2+WIeLDCmRaa13QGpnw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q86Y82 intact:EBI-8853273 intact:EBI-2691717|uniprotkb:B1AJQ7|uniprotkb:O95564|ensembl:ENSP00000363054 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:stx12_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stone et al. (2007) pubmed:17301141|imex:IM-25879 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9005424|imex:IM-25879-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) refseq:NP_803173.1|ensembl:ENSG00000117758(gene)|ensembl:ENST00000373943(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0050821"(protein stabilization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:Q86Y82|rcsb pdb:2DNX|dip:DIP-44225N - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Fig. 5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/11/18 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:kSTOaE08HK8SpI19dBZRZbOVCGw9606 intact-crc:65214C614980EA35|rigid:gz0CcmML2+WIeLDCmRaa13QGpnw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WMX2-PRO_0000037550 uniprotkb:Q9WMX2-PRO_0000037552 intact:EBI-8853273 intact:EBI-9005440 psi-mi:q9wmx2-pro_0000037550(display_long) psi-mi:q9wmx2-pro_0000037552(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stone et al. (2007) pubmed:17301141|imex:IM-25879 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9005424|imex:IM-25879-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-710918(chain-parent) intact:EBI-710918(chain-parent) - chain-seq-start:1712|chain-seq-end:1972 chain-seq-start:2420|chain-seq-end:3010 figure legend:Fig. 5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/11/18 2017/09/02 rogid:peGklEMd2cYv6RSI93fnVUXwUu8333284 rogid:4d6fo8km49QSX5eITFjOoXs8UL0333284 intact-crc:65214C614980EA35|rigid:gz0CcmML2+WIeLDCmRaa13QGpnw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)