#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96MT3	uniprotkb:Q92997	intact:EBI-2348662|uniprotkb:Q14C83|uniprotkb:Q71QF8|uniprotkb:Q96N00|ensembl:ENSP00000345064|ensembl:ENSP00000398947|ensembl:ENSP00000401060|ensembl:ENSP00000448359|ensembl:ENSP00000449819|ensembl:ENSP00000491051|ensembl:ENSP00000491228|ensembl:ENSP00000492332|ensembl:ENSP00000492644|ensembl:ENSP00000492763	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:pric1_human(display_long)|uniprotkb:PRICKLE1(gene name)|psi-mi:PRICKLE1(display_short)|uniprotkb:RILP(gene name synonym)|uniprotkb:REST/NRSF-interacting LIM domain protein 1(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chan et al. (2006)	pubmed:17030191|imex:IM-22156	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8850502|imex:IM-22156-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536248.1|refseq:XP_011536249.1|refseq:NP_001138353.1|refseq:NP_001138354.1|refseq:NP_001138355.1|refseq:NP_694571.2|refseq:XP_016874327.1|refseq:XP_016874328.1|refseq:XP_016874329.1|ensembl:ENSG00000139174(gene)|ensembl:ENST00000345127(transcript)|ensembl:ENST00000445766(transcript)|ensembl:ENST00000455697(transcript)|ensembl:ENST00000548696(transcript)|ensembl:ENST00000552240(transcript)|ensembl:ENST00000639566(transcript)|ensembl:ENST00000639589(transcript)|ensembl:ENST00000639958(transcript)|ensembl:ENST00000640055(transcript)|ensembl:ENST00000640132(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000691"(negative regulation of cardiac muscle cell myoblast differentiation)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033723|interpro:IPR033726|interpro:IPR033727|reactome:R-HSA-4608870	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/11/13	2014/10/16	rogid:Ja2xuOriMFG/HYyzg7JuPnFlaOM9606	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:B41DE58CC829676B|rigid:oZPU5KE0Vj1pPzXQm1geBhYiVGs	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q92997	uniprotkb:Q96MT3	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-2348662|uniprotkb:Q14C83|uniprotkb:Q71QF8|uniprotkb:Q96N00|ensembl:ENSP00000345064|ensembl:ENSP00000398947|ensembl:ENSP00000401060|ensembl:ENSP00000448359|ensembl:ENSP00000449819|ensembl:ENSP00000491051|ensembl:ENSP00000491228|ensembl:ENSP00000492332|ensembl:ENSP00000492644|ensembl:ENSP00000492763	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:pric1_human(display_long)|uniprotkb:PRICKLE1(gene name)|psi-mi:PRICKLE1(display_short)|uniprotkb:RILP(gene name synonym)|uniprotkb:REST/NRSF-interacting LIM domain protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chan et al. (2006)	pubmed:17030191|imex:IM-22156	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8850510|imex:IM-22156-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	refseq:XP_011536248.1|refseq:XP_011536249.1|refseq:NP_001138353.1|refseq:NP_001138354.1|refseq:NP_001138355.1|refseq:NP_694571.2|refseq:XP_016874327.1|refseq:XP_016874328.1|refseq:XP_016874329.1|ensembl:ENSG00000139174(gene)|ensembl:ENST00000345127(transcript)|ensembl:ENST00000445766(transcript)|ensembl:ENST00000455697(transcript)|ensembl:ENST00000548696(transcript)|ensembl:ENST00000552240(transcript)|ensembl:ENST00000639566(transcript)|ensembl:ENST00000639589(transcript)|ensembl:ENST00000639958(transcript)|ensembl:ENST00000640055(transcript)|ensembl:ENST00000640132(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000691"(negative regulation of cardiac muscle cell myoblast differentiation)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033723|interpro:IPR033726|interpro:IPR033727|reactome:R-HSA-4608870	-	-	-	figure legend:Fig. 4B, C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/11/13	2014/10/16	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:Ja2xuOriMFG/HYyzg7JuPnFlaOM9606	intact-crc:62F77813CA0907A7|rigid:oZPU5KE0Vj1pPzXQm1geBhYiVGs	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92997	uniprotkb:Q96MT3	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-2348662|uniprotkb:Q14C83|uniprotkb:Q71QF8|uniprotkb:Q96N00|ensembl:ENSP00000345064|ensembl:ENSP00000398947|ensembl:ENSP00000401060|ensembl:ENSP00000448359|ensembl:ENSP00000449819|ensembl:ENSP00000491051|ensembl:ENSP00000491228|ensembl:ENSP00000492332|ensembl:ENSP00000492644|ensembl:ENSP00000492763	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:pric1_human(display_long)|uniprotkb:PRICKLE1(gene name)|psi-mi:PRICKLE1(display_short)|uniprotkb:RILP(gene name synonym)|uniprotkb:REST/NRSF-interacting LIM domain protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chan et al. (2006)	pubmed:17030191|imex:IM-22156	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-8850483|imex:IM-22156-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	refseq:XP_011536248.1|refseq:XP_011536249.1|refseq:NP_001138353.1|refseq:NP_001138354.1|refseq:NP_001138355.1|refseq:NP_694571.2|refseq:XP_016874327.1|refseq:XP_016874328.1|refseq:XP_016874329.1|ensembl:ENSG00000139174(gene)|ensembl:ENST00000345127(transcript)|ensembl:ENST00000445766(transcript)|ensembl:ENST00000455697(transcript)|ensembl:ENST00000548696(transcript)|ensembl:ENST00000552240(transcript)|ensembl:ENST00000639566(transcript)|ensembl:ENST00000639589(transcript)|ensembl:ENST00000639958(transcript)|ensembl:ENST00000640055(transcript)|ensembl:ENST00000640132(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000691"(negative regulation of cardiac muscle cell myoblast differentiation)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033723|interpro:IPR033726|interpro:IPR033727|reactome:R-HSA-4608870	-	-	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/11/13	2014/10/16	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:Ja2xuOriMFG/HYyzg7JuPnFlaOM9606	intact-crc:420B12542A480478|rigid:oZPU5KE0Vj1pPzXQm1geBhYiVGs	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)