#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P80645	uniprotkb:P80644	intact:EBI-561637|ensemblbacteria:AAC74021|ensemblbacteria:BAA35690|uniprotkb:P75852|uniprotkb:Q9RM46	intact:EBI-1121047|uniprotkb:P75854|ensemblbacteria:AAC74023|ensemblbacteria:BAA35692	psi-mi:ssud_ecoli(display_long)|uniprotkb:Sulfate starvation-induced protein 6(gene name synonym)|uniprotkb:ycbN(gene name synonym)|uniprotkb:FMNH2-dependent aliphatic sulfonate monooxygenase(gene name synonym)|uniprotkb:ssuD(gene name)|psi-mi:ssuD(display_short)|uniprotkb:b0935(locus name)|uniprotkb:JW0918(locus name)	psi-mi:ssue_ecoli(display_long)|uniprotkb:ycbP(gene name synonym)|uniprotkb:Sulfate starvation-induced protein 4(gene name synonym)|uniprotkb:ssuE(gene name)|psi-mi:ssuE(display_short)|uniprotkb:b0937(locus name)|uniprotkb:JW0920(locus name)|uniprotkb:FMN reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Abdurachim et al. (2006)	pubmed:16997955|imex:IM-21531	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8786257|imex:IM-21531-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC74021(transcript)|ensemblbacteria:b0935(gene)|ensemblbacteria:BAA35690(gene)|ensemblbacteria:BAA35690(transcript)|go:"GO:0008726"(alkanesulfonate monooxygenase activity)|go:"GO:0009408"(response to heat)|go:"GO:0042802"(identical protein binding)|go:"GO:0046306"(alkanesulfonate catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990201"(alkanesulfonate monooxygenase complex)|interpro:IPR011251(Bacterial luciferase-like)|interpro:IPR019911|interpro:IPR036661|rcsb pdb:1M41|rcsb pdb:1NQK|refseq:NP_415455.1|refseq:WP_000056006.1|dip:DIP-10928N	refseq:WP_001263933.1|ensemblbacteria:AAC74023(transcript)|ensemblbacteria:b0937(gene)|ensemblbacteria:BAA35692(gene)|ensemblbacteria:BAA35692(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008752"(FMN reductase activity)|go:"GO:0009970"(cellular response to sulfate starvation)|go:"GO:0046306"(alkanesulfonate catabolic process)|go:"GO:0052873"("FMN reductase (NADPH) activity")|go:"GO:1990202"(FMN reductase complex)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR020048|interpro:IPR029039|rcsb pdb:4PTY|rcsb pdb:4PTZ|rcsb pdb:4PU0|rcsb pdb:6DQI|rcsb pdb:6DQO|rcsb pdb:6DQP|refseq:NP_415457.1|dip:DIP-10929N	-	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/02	2014/10/16	rogid:92cxlr0o2JzhcR9o4QpXEXRuLS083333	rogid:YpdiBKrDluG+Az9H6RVO5tTw3e083333	intact-crc:AF91C3A19AB51AE3|rigid:xPwcXkGbQsKsBmgVVPyNeweRwFc	false	his tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17621"	uniprotkb:P80644	intact:EBI-8786278|chebi:"CHEBI:42587"|chebi:"CHEBI:775745"|chebi:"CHEBI:4960"|chebi:"CHEBI:13317"|chebi:"CHEBI:21127"	intact:EBI-1121047|uniprotkb:P75854|ensemblbacteria:AAC74023|ensemblbacteria:BAA35692	psi-mi:fmn(display_short)|psi-mi:"CHEBI:17621"(display_long)|intact:"1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol"(synonym)|intact:Flavin mononucleotide(synonym)|intact:FLAVIN MONONUCLEOTIDE(synonym)|intact:FMN(synonym)|intact:"riboflavin 5'-(dihydrogen phosphate)"(synonym)|intact:riboflavin 5'-monophosphate(synonym)|intact:riboflavin 5'-phosphate(synonym)|intact:riboflavin monophosphate(synonym)|intact:Riboflavin-5-phosphate(synonym)|intact:riboflavine dihydrogen phosphate(synonym)|intact:"1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol"(iupac name)	psi-mi:ssue_ecoli(display_long)|uniprotkb:ycbP(gene name synonym)|uniprotkb:Sulfate starvation-induced protein 4(gene name synonym)|uniprotkb:ssuE(gene name)|psi-mi:ssuE(display_short)|uniprotkb:b0937(locus name)|uniprotkb:JW0920(locus name)|uniprotkb:FMN reductase(gene name synonym)	psi-mi:"MI:0016"(circular dichroism)	Abdurachim et al. (2006)	pubmed:16997955|imex:IM-21531	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8786272|imex:IM-21531-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:WP_001263933.1|ensemblbacteria:AAC74023(transcript)|ensemblbacteria:b0937(gene)|ensemblbacteria:BAA35692(gene)|ensemblbacteria:BAA35692(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008752"(FMN reductase activity)|go:"GO:0009970"(cellular response to sulfate starvation)|go:"GO:0046306"(alkanesulfonate catabolic process)|go:"GO:0052873"("FMN reductase (NADPH) activity")|go:"GO:1990202"(FMN reductase complex)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR020048|interpro:IPR029039|rcsb pdb:4PTY|rcsb pdb:4PTZ|rcsb pdb:4PU0|rcsb pdb:6DQI|rcsb pdb:6DQO|rcsb pdb:6DQP|refseq:NP_415457.1|dip:DIP-10929N	-	inchi key:FVTCRASFADXXNN-SCRDCRAPSA-N	-	figure legend:Fig. 4|comment:The SsuD-His construct was not added as a participant because the spectrum did not change significantly when SsuD-His was added to the reaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/02	2014/10/16	-	rogid:YpdiBKrDluG+Az9H6RVO5tTw3e083333	intact-crc:BF66E62D6EE5E922	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P80645	uniprotkb:P80644	intact:EBI-561637|ensemblbacteria:AAC74021|ensemblbacteria:BAA35690|uniprotkb:P75852|uniprotkb:Q9RM46	intact:EBI-1121047|uniprotkb:P75854|ensemblbacteria:AAC74023|ensemblbacteria:BAA35692	psi-mi:ssud_ecoli(display_long)|uniprotkb:Sulfate starvation-induced protein 6(gene name synonym)|uniprotkb:ycbN(gene name synonym)|uniprotkb:FMNH2-dependent aliphatic sulfonate monooxygenase(gene name synonym)|uniprotkb:ssuD(gene name)|psi-mi:ssuD(display_short)|uniprotkb:b0935(locus name)|uniprotkb:JW0918(locus name)	psi-mi:ssue_ecoli(display_long)|uniprotkb:ycbP(gene name synonym)|uniprotkb:Sulfate starvation-induced protein 4(gene name synonym)|uniprotkb:ssuE(gene name)|psi-mi:ssuE(display_short)|uniprotkb:b0937(locus name)|uniprotkb:JW0920(locus name)|uniprotkb:FMN reductase(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Abdurachim et al. (2006)	pubmed:16997955|imex:IM-21531	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8786567|imex:IM-21531-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC74021(transcript)|ensemblbacteria:b0935(gene)|ensemblbacteria:BAA35690(gene)|ensemblbacteria:BAA35690(transcript)|go:"GO:0008726"(alkanesulfonate monooxygenase activity)|go:"GO:0009408"(response to heat)|go:"GO:0042802"(identical protein binding)|go:"GO:0046306"(alkanesulfonate catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990201"(alkanesulfonate monooxygenase complex)|interpro:IPR011251(Bacterial luciferase-like)|interpro:IPR019911|interpro:IPR036661|rcsb pdb:1M41|rcsb pdb:1NQK|refseq:NP_415455.1|refseq:WP_000056006.1|dip:DIP-10928N	refseq:WP_001263933.1|ensemblbacteria:AAC74023(transcript)|ensemblbacteria:b0937(gene)|ensemblbacteria:BAA35692(gene)|ensemblbacteria:BAA35692(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008752"(FMN reductase activity)|go:"GO:0009970"(cellular response to sulfate starvation)|go:"GO:0046306"(alkanesulfonate catabolic process)|go:"GO:0052873"("FMN reductase (NADPH) activity")|go:"GO:1990202"(FMN reductase complex)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR020048|interpro:IPR029039|rcsb pdb:4PTY|rcsb pdb:4PTZ|rcsb pdb:4PU0|rcsb pdb:6DQI|rcsb pdb:6DQO|rcsb pdb:6DQP|refseq:NP_415457.1|dip:DIP-10929N	-	-	-	figure legend:Fig. 5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/02	2014/10/16	rogid:92cxlr0o2JzhcR9o4QpXEXRuLS083333	rogid:YpdiBKrDluG+Az9H6RVO5tTw3e083333	intact-crc:E2167405523499F0|rigid:xPwcXkGbQsKsBmgVVPyNeweRwFc	false	his tag:c-c	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17621"	uniprotkb:P80645	intact:EBI-8786278|chebi:"CHEBI:42587"|chebi:"CHEBI:775745"|chebi:"CHEBI:4960"|chebi:"CHEBI:13317"|chebi:"CHEBI:21127"	intact:EBI-561637|ensemblbacteria:AAC74021|ensemblbacteria:BAA35690|uniprotkb:P75852|uniprotkb:Q9RM46	psi-mi:fmn(display_short)|psi-mi:"CHEBI:17621"(display_long)|intact:"1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol"(synonym)|intact:Flavin mononucleotide(synonym)|intact:FLAVIN MONONUCLEOTIDE(synonym)|intact:FMN(synonym)|intact:"riboflavin 5'-(dihydrogen phosphate)"(synonym)|intact:riboflavin 5'-monophosphate(synonym)|intact:riboflavin 5'-phosphate(synonym)|intact:riboflavin monophosphate(synonym)|intact:Riboflavin-5-phosphate(synonym)|intact:riboflavine dihydrogen phosphate(synonym)|intact:"1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol"(iupac name)	psi-mi:ssud_ecoli(display_long)|uniprotkb:Sulfate starvation-induced protein 6(gene name synonym)|uniprotkb:ycbN(gene name synonym)|uniprotkb:FMNH2-dependent aliphatic sulfonate monooxygenase(gene name synonym)|uniprotkb:ssuD(gene name)|psi-mi:ssuD(display_short)|uniprotkb:b0935(locus name)|uniprotkb:JW0918(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Abdurachim et al. (2006)	pubmed:16997955|imex:IM-21531	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8786584|imex:IM-21531-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC74021(transcript)|ensemblbacteria:b0935(gene)|ensemblbacteria:BAA35690(gene)|ensemblbacteria:BAA35690(transcript)|go:"GO:0008726"(alkanesulfonate monooxygenase activity)|go:"GO:0009408"(response to heat)|go:"GO:0042802"(identical protein binding)|go:"GO:0046306"(alkanesulfonate catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990201"(alkanesulfonate monooxygenase complex)|interpro:IPR011251(Bacterial luciferase-like)|interpro:IPR019911|interpro:IPR036661|rcsb pdb:1M41|rcsb pdb:1NQK|refseq:NP_415455.1|refseq:WP_000056006.1|dip:DIP-10928N	-	inchi key:FVTCRASFADXXNN-SCRDCRAPSA-N	-	figure legend:Fig.s 6, 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.2x10^-9(molar)	2013/10/02	2014/10/16	-	rogid:92cxlr0o2JzhcR9o4QpXEXRuLS083333	intact-crc:D5E81027E664BB49	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17621"	uniprotkb:P80644	intact:EBI-8786278|chebi:"CHEBI:42587"|chebi:"CHEBI:775745"|chebi:"CHEBI:4960"|chebi:"CHEBI:13317"|chebi:"CHEBI:21127"	intact:EBI-1121047|uniprotkb:P75854|ensemblbacteria:AAC74023|ensemblbacteria:BAA35692	psi-mi:fmn(display_short)|psi-mi:"CHEBI:17621"(display_long)|intact:"1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol"(synonym)|intact:Flavin mononucleotide(synonym)|intact:FLAVIN MONONUCLEOTIDE(synonym)|intact:FMN(synonym)|intact:"riboflavin 5'-(dihydrogen phosphate)"(synonym)|intact:riboflavin 5'-monophosphate(synonym)|intact:riboflavin 5'-phosphate(synonym)|intact:riboflavin monophosphate(synonym)|intact:Riboflavin-5-phosphate(synonym)|intact:riboflavine dihydrogen phosphate(synonym)|intact:"1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphono-D-ribitol"(iupac name)	psi-mi:ssue_ecoli(display_long)|uniprotkb:ycbP(gene name synonym)|uniprotkb:Sulfate starvation-induced protein 4(gene name synonym)|uniprotkb:ssuE(gene name)|psi-mi:ssuE(display_short)|uniprotkb:b0937(locus name)|uniprotkb:JW0920(locus name)|uniprotkb:FMN reductase(gene name synonym)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Abdurachim et al. (2006)	pubmed:16997955|imex:IM-21531	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8786584|imex:IM-21531-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:WP_001263933.1|ensemblbacteria:AAC74023(transcript)|ensemblbacteria:b0937(gene)|ensemblbacteria:BAA35692(gene)|ensemblbacteria:BAA35692(transcript)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008752"(FMN reductase activity)|go:"GO:0009970"(cellular response to sulfate starvation)|go:"GO:0046306"(alkanesulfonate catabolic process)|go:"GO:0052873"("FMN reductase (NADPH) activity")|go:"GO:1990202"(FMN reductase complex)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR020048|interpro:IPR029039|rcsb pdb:4PTY|rcsb pdb:4PTZ|rcsb pdb:4PU0|rcsb pdb:6DQI|rcsb pdb:6DQO|rcsb pdb:6DQP|refseq:NP_415457.1|dip:DIP-10929N	-	inchi key:FVTCRASFADXXNN-SCRDCRAPSA-N	-	figure legend:Fig.s 6, 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.2x10^-9(molar)	2013/10/02	2014/10/16	-	rogid:YpdiBKrDluG+Az9H6RVO5tTw3e083333	intact-crc:D5E81027E664BB49	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)