#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O54918 uniprotkb:P97287 intact:EBI-526067|uniprotkb:O54919|uniprotkb:O54920|uniprotkb:A2ALQ6|ensembl:ENSMUSP00000105970 intact:EBI-707292|uniprotkb:D2K6L9|uniprotkb:Q3TUS0|uniprotkb:Q792P0|uniprotkb:Q9CRI4|ensembl:ENSMUSP00000044048 psi-mi:b2l11_mouse(display_long)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)|uniprotkb:Bcl2l11(gene name)|psi-mi:Bcl2l11(display_short)|uniprotkb:Bim(gene name synonym) psi-mi:mcl1_mouse(display_long)|uniprotkb:Bcl-2-related protein EAT/mcl1(gene name synonym)|uniprotkb:Mcl1(gene name)|psi-mi:Mcl1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Maurer et al. (2006) imex:IM-21573|pubmed:16543145 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-8793320|imex:IM-21573-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033884.1|refseq:NP_997563.1|refseq:NP_997564.1|ensembl:ENSMUSG00000027381(gene)|ensembl:ENSMUST00000110341(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|rcsb pdb:1PQ1|reactome:R-MMU-111446|reactome:R-MMU-111453|reactome:R-MMU-193648|dip:DIP-29214N refseq:NP_032588.1|dip:DIP-33343N|ensembl:ENSMUSG00000038612(gene)|ensembl:ENSMUST00000037947(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034097"(response to cytokine)|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2ROC|rcsb pdb:2ROD|rcsb pdb:3D7V|rcsb pdb:3IO9|rcsb pdb:4BPI|rcsb pdb:4BPJ|rcsb pdb:4G35|rcsb pdb:5KU9|rcsb pdb:5MES|rcsb pdb:5MEV|rcsb pdb:5VX2|rcsb pdb:6DM8|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051400"(BH domain binding)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR013281(Apoptosis regulator, Mcl-1)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR036834|rcsb pdb:1WSX|rcsb pdb:2JM6|rcsb pdb:2NL9|rcsb pdb:2NLA - - - figure legend:fig 6D|antagonist:IL-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-fl5.12)|taxid:10090(murine FL5.12 pro-B-cell lymphoid cell line) - 2013/10/11 2014/10/16 rogid:Yv0iM/Lv2orJjfRLaDKto6SFCIQ10090 rogid:mzEFIihn4nh/O1UVSXggXEpJOKg10090 intact-crc:F14AAFB01EB499B7|rigid:+5xIzo86JBM2aQOVw+ddJ5WylaA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)