#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:17345" uniprotkb:Q9P2T1 intact:EBI-9007299|chebi:"CHEBI:13341"|chebi:"CHEBI:14381"|chebi:"CHEBI:129502"|chebi:"CHEBI:24449"|chebi:"CHEBI:24450"|chebi:"CHEBI:29058"|chebi:"CHEBI:40119"|chebi:"CHEBI:42979"|chebi:"CHEBI:42615"|chebi:"CHEBI:42647"|chebi:"CHEBI:42831"|chebi:"CHEBI:42887"|chebi:"CHEBI:42892"|chebi:"CHEBI:47450"|chebi:"CHEBI:5228" intact:EBI-2806548|uniprotkb:Q567T0|uniprotkb:Q6IAJ8|uniprotkb:D3DS66|ensembl:ENSP00000347449|ensembl:ENSP00000382369|ensembl:ENSP00000453299|ensembl:ENSP00000494224|ensembl:ENSP00000495583|ensembl:ENSP00000496504|uniprotkb:Q86T14 psi-mi:gmp(display_short)|psi-mi:"CHEBI:17345"(display_long)|intact:5'-GMP(synonym)|intact:GMP(synonym)|intact:Guanosine 5'-monophosphate(synonym)|intact:Guanosine 5'-phosphate(synonym)|intact:Guanosine monophosphate(synonym)|intact:guanosine-5'-monophosphate(synonym)|intact:Guanylic acid(synonym)|intact:pG(synonym)|intact:5'-guanylic acid(iupac name)|intact:"[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen phosphate"(iupac name) psi-mi:gmpr2_human(display_long)|uniprotkb:Guanosine 5'-monophosphate oxidoreductase 2(gene name synonym)|uniprotkb:GMPR2(gene name)|psi-mi:GMPR2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Li et al. (2006) pubmed:16359702|imex:IM-21793 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9005496|pdbe:2A7R|imex:IM-21793-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001269950.1|refseq:NP_001269951.1|refseq:NP_001269952.1|refseq:NP_001002000.1|refseq:NP_001002001.1|refseq:NP_001002002.1|refseq:NP_057660.2|ensembl:ENSG00000100938(gene)|ensembl:ENSG00000284752(gene)|ensembl:ENST00000355299(transcript)|ensembl:ENST00000399440(transcript)|ensembl:ENST00000559836(transcript)|ensembl:ENST00000642276(transcript)|ensembl:ENST00000644066(transcript)|ensembl:ENST00000647320(transcript)|go:"GO:0003920"(GMP reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0046037"(GMP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1902560"(GMP reductase complex)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:2A7R|rcsb pdb:2BZN|rcsb pdb:2C6Q|reactome:R-HSA-74217|interpro:IPR005993(Guanosine monophosphate reductase 1) - inchi key:RQFCJASXJCIDSX-UUOKFMHZSA-N - 3d-r-factors:"R-factor:0.228 R-free:0.276"|3d-resolution:3.0 A|figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2019/01/30 - rogid:/k9kNXIA6CIiiNIhpdrXTrR5wE89606 intact-crc:E02CA4CC9CA8A163 false - sufficient binding region:1-348 3 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)