#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671685|imex:IM-20595-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 1c, 2a|comment:This crystal assembly is only described in the paper but not in PDB.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:306E980AA8DEAD34|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	L-selenomethionine:?-?|sufficient binding region:1-50	L-selenomethionine:?-?|sufficient binding region:1-50	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671694|wwpdb:1xrx|imex:IM-20595-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 1d|3d-r-factors:All = 0.22; Rwork = 0.22; Rfree = 0.24|3d-resolution:2.15 A|3d-structure:In PDB only a dimer and an octomer are assembled, however, the authors mention that the dimers form essentially filaments which could be recorded as multimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:B44D56E3A30B71B4|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	L-selenomethionine:?-?|sufficient binding region:1-50	L-selenomethionine:?-?|sufficient binding region:1-50	8	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671679|wwpdb:1xrx|imex:IM-20595-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 1b|3d-r-factors:All = 0.22; Rwork = 0.22; Rfree = 0.24|3d-resolution:2.15 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:BEEDDC7765A13C68|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	sufficient binding region:1-50|L-selenomethionine:?-?	sufficient binding region:1-50|L-selenomethionine:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0071"(molecular sieving)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671935|imex:IM-20595-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 2d|comment:"SeqA form filaments which are disrupted by certain mutations (see EBI-6671939)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:C9FF8A78669C96A5|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0071"(molecular sieving)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671939|imex:IM-20595-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 2d|comment:SeqA form filaments which are disrupted by any of these mutations.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:7DA8BAEEE9D601CC|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	mutation:25-25|mutation:18-18|mutation:21-21	mutation:25-25|mutation:18-18|mutation:21-21	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671996|imex:IM-20595-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 2e|comment:SeqA forms filaments which are disrupted by any of these mutations and forms, amongst other homotetramers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:8ADA7D413D19CA37|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	mutation:21-21|mutation:18-18	mutation:21-21|mutation:18-18	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671968|imex:IM-20595-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 2e|comment:SeqA forms filaments which are disrupted by any of these mutations and forms, amongst other homodimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:D37A9AD7BFF3110B|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	mutation:18-18|mutation:21-21|mutation:25-25	mutation:18-18|mutation:21-21|mutation:25-25	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671978|imex:IM-20595-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 2e|comment:SeqA forms filaments which are disrupted by this mutation and forms, amongst other homooctamers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:9F7FF4668A34D7F5|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	mutation:21-21	mutation:21-21	8	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Guarné et al. (2005)	pubmed:15933720|imex:IM-20595	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671964|imex:IM-20595-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 2e|comment:"SeqA forms filaments which are disrupted by certain mutations (see EBI-6671968, EBI-6671978, EBI-6671996)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:4EDB559DEF8F1589|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)