#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSG00000133703 uniprotkb:Q8N693 intact:EBI-8830056 intact:EBI-3921985|ensembl:ENSP00000361669|uniprotkb:B0QYU3|uniprotkb:Q7Z6K7 psi-mi:kras_human_gene(display_short)|psi-mi:ENSG00000133703(display_long) psi-mi:esx1_human(display_long)|uniprotkb:ESX1(gene name)|psi-mi:ESX1(display_short)|uniprotkb:ESX1L(gene name synonym)|uniprotkb:ESX1R(gene name synonym)|uniprotkb:Extraembryonic, spermatogenesis, homeobox 1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Yanagihara et al. (2005) pubmed:15897875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1264"(NTNU) intact:EBI-8788772 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000123576(gene)|ensembl:ENST00000372588(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013847(POU)|interpro:IPR017970|refseq:NP_703149.1 - - - figure legend:Fig 4d|causality statement:Q8N693 decreases expression at RNA level of ENSG00000133703|comment:"Q8N693 decreases expression at RNA level of ENSG00000133703 (decreases activity of intronic regulatory region (SO:0001492) as measured in reporter gene assay). Reported in Figure 4b"|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2013/10/05 2014/10/16 - rogid:DOb7X+Wigujg4OEYvGi4F35M+rk9606 intact-crc:87D7B50F574BCA92 false - sufficient binding region:1-229|myc tag:?-? - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr) intact:EBI-8830061 uniprotkb:Q8N693 - intact:EBI-3921985|ensembl:ENSP00000361669|uniprotkb:B0QYU3|uniprotkb:Q7Z6K7 psi-mi:kras_human_dna_51bp_intronic(display_short)|psi-mi:EBI-8830061(display_long) psi-mi:esx1_human(display_long)|uniprotkb:ESX1(gene name)|psi-mi:ESX1(display_short)|uniprotkb:ESX1L(gene name synonym)|uniprotkb:ESX1R(gene name synonym)|uniprotkb:Extraembryonic, spermatogenesis, homeobox 1(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Yanagihara et al. (2005) pubmed:15897875 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-8839326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000133703 ensembl:ENSG00000123576(gene)|ensembl:ENST00000372588(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013847(POU)|interpro:IPR017970|refseq:NP_703149.1 - - - figure legend:Fig 4c|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/05 2014/10/16 - rogid:DOb7X+Wigujg4OEYvGi4F35M+rk9606 intact-crc:450652843BF44220 false 32p radiolabel:?-?|sufficient binding region:?-? sufficient binding region:1-229 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-8830061 intact:EBI-8830061 - - psi-mi:kras_human_dna_51bp_intronic(display_short)|psi-mi:EBI-8830061(display_long) psi-mi:kras_human_dna_51bp_intronic(display_short)|psi-mi:EBI-8830061(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Yanagihara et al. (2005) pubmed:15897875 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-8788794 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0319"(deoxyribonucleic acid) ensembl:ENSG00000133703 ensembl:ENSG00000133703 - - - figure legend:Fig 4c|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/05 2014/10/16 - - intact-crc:78B63EBCAED4A0F8 false 32p radiolabel:?-?|sufficient binding region:?-? sufficient binding region:23-31|mutation:23-23,29-31 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-8830061 uniprotkb:Q8N693 - intact:EBI-3921985|ensembl:ENSP00000361669|uniprotkb:B0QYU3|uniprotkb:Q7Z6K7 psi-mi:kras_human_dna_51bp_intronic(display_short)|psi-mi:EBI-8830061(display_long) psi-mi:esx1_human(display_long)|uniprotkb:ESX1(gene name)|psi-mi:ESX1(display_short)|uniprotkb:ESX1L(gene name synonym)|uniprotkb:ESX1R(gene name synonym)|uniprotkb:Extraembryonic, spermatogenesis, homeobox 1(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Yanagihara et al. (2005) pubmed:15897875 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-8788794 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000133703 ensembl:ENSG00000123576(gene)|ensembl:ENST00000372588(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013847(POU)|interpro:IPR017970|refseq:NP_703149.1 - - - figure legend:Fig 4c|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/05 2014/10/16 - rogid:DOb7X+Wigujg4OEYvGi4F35M+rk9606 intact-crc:78B63EBCAED4A0F8 false 32p radiolabel:?-?|sufficient binding region:?-? sufficient binding region:1-229 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) intact:EBI-8830061 uniprotkb:Q8N693 - intact:EBI-3921985|ensembl:ENSP00000361669|uniprotkb:B0QYU3|uniprotkb:Q7Z6K7 psi-mi:kras_human_dna_51bp_intronic(display_short)|psi-mi:EBI-8830061(display_long) psi-mi:esx1_human(display_long)|uniprotkb:ESX1(gene name)|psi-mi:ESX1(display_short)|uniprotkb:ESX1L(gene name synonym)|uniprotkb:ESX1R(gene name synonym)|uniprotkb:Extraembryonic, spermatogenesis, homeobox 1(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Yanagihara et al. (2005) pubmed:15897875 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1264"(NTNU) intact:EBI-8788823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0319"(deoxyribonucleic acid) psi-mi:"MI:0326"(protein) ensembl:ENSG00000133703 ensembl:ENSG00000123576(gene)|ensembl:ENST00000372588(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013847(POU)|interpro:IPR017970|refseq:NP_703149.1 - - - figure legend:Fig 4c|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/05 2014/10/16 - rogid:DOb7X+Wigujg4OEYvGi4F35M+rk9606 intact-crc:1E89163F9625FAE0 false 32p radiolabel:?-?|sufficient binding region:?-? sufficient binding region:1-229 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)