#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O95551	uniprotkb:P14921	intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6867621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	-	-	-	figure legend:fig 1a and materials and methods|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/03/26	2014/10/16	rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:9442D5A0E3C1A352|rigid:TSuETDJo+bgu6wrchV2mdEJTxeU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14921	uniprotkb:Q9UER7	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6570628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N	-	-	-	figure legend:fig 1a and materials and methods|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/03/26	2014/10/16	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606	intact-crc:A494F1208CC946D8|rigid:ck0AW10h2ZJPAszvolK2caOUzeM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23497	uniprotkb:P14921	intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6867615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	-	-	-	figure legend:fig 1a and materials and methods|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/03/26	2014/10/16	rogid:+rzb0oseufnoLe2QXNCvZlV89x89606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:C8A290C67D766087|rigid:QrrcHCbdjc58tsQnnDaRLdNdgvM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23497	uniprotkb:P14921	intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6570646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	-	-	-	figure legend:fig 1b|curation depth:mimix curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/03/26	2014/10/16	rogid:+rzb0oseufnoLe2QXNCvZlV89x89606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:7472A205576CDFB6|rigid:QrrcHCbdjc58tsQnnDaRLdNdgvM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23497-2	uniprotkb:Q01543	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-2271018|uniprotkb:B4DFV4|uniprotkb:Q14319|uniprotkb:Q92480|uniprotkb:Q9UE07|uniprotkb:B2R8H2|uniprotkb:B4DTC6|uniprotkb:G3V183|ensembl:ENSP00000433488	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:fli1_human(display_long)|uniprotkb:FLI1(gene name)|psi-mi:FLI1(display_short)|uniprotkb:Proto-oncogene Fli-1(gene name synonym)|uniprotkb:Transcription factor ERGB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6570673	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	refseq:NP_002008.2|refseq:NP_001161153.1|refseq:NP_001257939.1|refseq:NP_001257941.1|go:"GO:0030154"(cell differentiation)|go:"GO:0035855"(megakaryocyte development)|ensembl:ENSG00000151702(gene)|ensembl:ENST00000527786(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007599"(hemostasis)|go:"GO:0008015"(blood circulation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016604"(nuclear body)|refseq:XP_011541003.1|refseq:XP_016872894.1|refseq:XP_016872895.1|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035573|interpro:IPR035575|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1FLI|rcsb pdb:1X66|rcsb pdb:2YTU|rcsb pdb:5E8G|rcsb pdb:5E8I|rcsb pdb:5JVT|rcsb pdb:6VG2|rcsb pdb:6VG8|rcsb pdb:6VGD|reactome:R-HSA-9616222	-	isoform-comment:Major isoform.	-	figure legend:fig 1c|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/26	2014/10/16	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:WCQw202NBbJxHliWsFCoYNv45WM9606	intact-crc:2FF9F6A378F17422|rigid:5MNcpem9M2LOr1OXa5CTUuugoTA	false	sufficient binding region:10-480	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P23497-2	uniprotkb:P14921-1	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-913224|ensembl:ENSP00000324578	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:p14921-1(display_long)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:Ets-1 p51(isoform synonym)	psi-mi:"MI:0096"(pull down)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6570673	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	intact:EBI-913209(ets1_human)|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)	-	isoform-comment:Major isoform.	-	figure legend:fig 1c|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/26	2014/10/16	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:2FF9F6A378F17422|rigid:5MNcpem9M2LOr1OXa5CTUuugoTA	false	sufficient binding region:10-480	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P23497-2	uniprotkb:P14921-2	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-913228|ensembl:ENSP00000433500	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:p14921-2(display_long)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)|uniprotkb:p54(gene name synonym)|uniprotkb:Ets-1 p42(isoform synonym)	psi-mi:"MI:0096"(pull down)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6570673	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	intact:EBI-913209(ets1_human)|ensembl:ENSG00000134954(gene)|ensembl:ENST00000526145(transcript)	-	isoform-comment:Major isoform.	-	figure legend:fig 1c|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/03/26	2014/10/16	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:9fwH9HMx7ozV1Qss8DrZyu/SlkE9606	intact-crc:2FF9F6A378F17422|rigid:5MNcpem9M2LOr1OXa5CTUuugoTA	false	sufficient binding region:10-480	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P23497	uniprotkb:P14921	intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6589333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	-	-	-	figure legend:fig 1d|curation depth:mimix curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2013/03/26	2014/10/16	rogid:+rzb0oseufnoLe2QXNCvZlV89x89606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:FA481F156D77BDCF|rigid:QrrcHCbdjc58tsQnnDaRLdNdgvM	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P14921	uniprotkb:P23497	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6589346	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE	-	-	-	figure legend:fig 1e|curation depth:mimix curation	taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma)	-	2013/03/26	2014/10/16	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	rogid:+rzb0oseufnoLe2QXNCvZlV89x89606	intact-crc:16A7E1FB1290D286|rigid:QrrcHCbdjc58tsQnnDaRLdNdgvM	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P23497-2	uniprotkb:P14921	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Yordy et al. (2004)	pubmed:15247905	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6589357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	go:"GO:0005634"(nucleus)	isoform-comment:Major isoform.	-	figure legend:fig 2|curation depth:mimix curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/03/26	2014/10/16	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:32D3F87DAE54424C|rigid:MgcHLyXyHkJZcDeTBZbbL7s1KOw	false	-	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)