#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20591 uniprotkb:P27958-PRO_0000037576 intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712 intact:EBI-8753518 psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym) psi-mi:p27958-pro_0000037576(display_long) psi-mi:"MI:0663"(confocal microscopy) Melén et al. (2004) pubmed:15221897|imex:IM-25998 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-8788892|imex:IM-25998-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733 intact:EBI-706378(chain-parent) - - chain-seq-start:1973|chain-seq-end:2420 figure legend:Fig. 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2013/10/06 2017/09/02 rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606 rogid:QUtsxvdJhyaJg2Xu4JFrW5Tay2A63746 intact-crc:8F20CE017C6CA920|rigid:s5fh3THtRTMxcsb96K21YU120wo false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P27958-PRO_0000037575 uniprotkb:P20591 intact:EBI-8763498 intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712 psi-mi:p27958-pro_0000037575(display_long) psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Melén et al. (2004) pubmed:15221897|imex:IM-25998 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-8788886|imex:IM-25998-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733 - chain-seq-start:1712|chain-seq-end:1972 - figure legend:Fig. 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2013/10/06 2017/09/02 rogid:ciVyawOEfr/vRqtj/2hRgz/7zEw63746 rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606 intact-crc:04938E03F1A63936|rigid:ipLecdMNiW8PArIOfqaDitx8RTM false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)