#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0A988	uniprotkb:P69931	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Kurz et al. (2004)	pubmed:15150238|imex:IM-18732	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6597341|imex:IM-18732-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	-	caution:This sequence has been withdrawn from Uniprot.	comment:according to authors, similar results were found with 10x histidine tag.	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/04/02	2014/10/16	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	intact-crc:1500489DED0D7871|rigid:MP0+ueUvbIAk4nO8VSxixb9SGW4	false	his tag:n-n	maltose binding protein tag:n-n|mutation decreasing interaction:7-7,9-9|mutation decreasing interaction:9-9,10-10	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P69931	uniprotkb:P69931	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Kurz et al. (2004)	pubmed:15150238|imex:IM-18732	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6597627|imex:IM-18732-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	-	comment:according to authors, similar results were found with 10x histidine tag.	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/04/02	2014/10/16	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	intact-crc:32540D284E990B15|rigid:MP0+ueUvbIAk4nO8VSxixb9SGW4	false	maltose binding protein tag:n-n	necessary binding region:4-13|mutation:12-13,4-5|mutation:4-5,10-13	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P69931	uniprotkb:P0A988	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Kurz et al. (2004)	pubmed:15150238|imex:IM-18732	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6597627|imex:IM-18732-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	-	comment:according to authors, similar results were found with 10x histidine tag.	caution:This sequence has been withdrawn from Uniprot.	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/04/02	2014/10/16	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	intact-crc:32540D284E990B15|rigid:MP0+ueUvbIAk4nO8VSxixb9SGW4	false	maltose binding protein tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P0A988	uniprotkb:P69931	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	intact:EBI-545453|uniprotkb:P76570|uniprotkb:P76979|ensemblbacteria:BAA16384|ensemblbacteria:AAC75549	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:hda_ecoli(display_long)|uniprotkb:hda(gene name)|psi-mi:hda(display_short)|uniprotkb:yfgE(gene name synonym)|uniprotkb:DnaA paralog(gene name synonym)|uniprotkb:idaB(gene name synonym)|uniprotkb:f248c(orf name)|uniprotkb:JW5397(locus name)|uniprotkb:b2496(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kurz et al. (2004)	pubmed:15150238|imex:IM-18732	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6597364|imex:IM-18732-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	refseq:NP_416991.2|ensemblbacteria:AAC75549(transcript)|ensemblbacteria:b2496(gene)|ensemblbacteria:BAA16384(gene)|ensemblbacteria:BAA16384(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR017788(DnaA regulatory inactivator Hda)|interpro:IPR020591|interpro:IPR022864|interpro:IPR027417|dip:DIP-48006N|refseq:WP_001307333.1	-	caution:This sequence has been withdrawn from Uniprot.	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/04/02	2014/10/16	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	rogid:oLydtsoKho23cOIxa1+hXs75tD483333	intact-crc:07882FA15714DBBE|rigid:MP0+ueUvbIAk4nO8VSxixb9SGW4	false	his tag:n-n	mutation disrupting interaction:9-9,10-10|mutation disrupting interaction:7-7,9-9|maltose binding protein tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)