#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17948 uniprotkb:P15692-4 intact:EBI-1026718|uniprotkb:B0LPF1|uniprotkb:B3FR89|uniprotkb:B5A923|uniprotkb:O60722|uniprotkb:P16057|uniprotkb:Q12954|uniprotkb:A8KA71|ensembl:ENSP00000282397|uniprotkb:A3E342|uniprotkb:A3E344|uniprotkb:B2BF46|uniprotkb:B2BF47|uniprotkb:F5H5L6|uniprotkb:B2BF48 intact:EBI-1026691|ensembl:ENSP00000429643 psi-mi:vgfr1_human(display_long)|uniprotkb:Vascular permeability factor receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor FLT(gene name synonym)|uniprotkb:Tyrosine-protein kinase FRT(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 1(gene name synonym)|uniprotkb:FLT1(gene name)|psi-mi:FLT1(display_short)|uniprotkb:FLT(gene name synonym)|uniprotkb:FRT(gene name synonym)|uniprotkb:VEGFR1(gene name synonym) psi-mi:p15692-4(display_long)|uniprotkb:VEGF(isoform synonym)|uniprotkb:VEGFA(gene name)|psi-mi:VEGFA(display_short)|uniprotkb:VEGF(gene name synonym)|uniprotkb:Vascular permeability factor(gene name synonym) psi-mi:"MI:0405"(competition binding) de et al. (1992) pubmed:1312256|imex:IM-22104 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9006093|imex:IM-22104-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153392.1|refseq:NP_002010.2|ensembl:ENSG00000102755(gene)|ensembl:ENST00000282397(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036323"(vascular endothelial growth factor receptor-1 signaling pathway)|go:"GO:0036332"(placental growth factor-activated receptor activity)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009135(Vascular endothelial growth factor receptor 1, VEGFR1, N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|mint:P17948|rcsb pdb:1FLT|rcsb pdb:1QSV|rcsb pdb:1QSZ|rcsb pdb:1QTY|rcsb pdb:1RV6|rcsb pdb:2XAC|rcsb pdb:3HNG|rcsb pdb:4CKV|rcsb pdb:4CL7|rcsb pdb:5ABD|rcsb pdb:5EX3|rcsb pdb:5T89|reactome:R-HSA-194306|reactome:R-HSA-195399|interpro:IPR041348|refseq:NP_001153502.1|refseq:NP_001153503.1|dip:DIP-643N intact:EBI-1026643(vegfa_human)|ensembl:ENSG00000112715(gene)|ensembl:ENST00000523950(transcript) - - - figure legend:Fig.2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2014/10/16 rogid:AfSO/WFuXISaK/PbB/s2Vv+vLFE9606 rogid:/DdgEEe0/rYnemiYvqxeQ+KiXXs9606 intact-crc:8C1DF4309E3D2684|rigid:cs5mJ/dDnmfnmsXcWmIPcgD1Zt0 false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P17948 uniprotkb:P15692-4 intact:EBI-1026718|uniprotkb:B0LPF1|uniprotkb:B3FR89|uniprotkb:B5A923|uniprotkb:O60722|uniprotkb:P16057|uniprotkb:Q12954|uniprotkb:A8KA71|ensembl:ENSP00000282397|uniprotkb:A3E342|uniprotkb:A3E344|uniprotkb:B2BF46|uniprotkb:B2BF47|uniprotkb:F5H5L6|uniprotkb:B2BF48 intact:EBI-1026691|ensembl:ENSP00000429643 psi-mi:vgfr1_human(display_long)|uniprotkb:Vascular permeability factor receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor FLT(gene name synonym)|uniprotkb:Tyrosine-protein kinase FRT(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 1(gene name synonym)|uniprotkb:FLT1(gene name)|psi-mi:FLT1(display_short)|uniprotkb:FLT(gene name synonym)|uniprotkb:FRT(gene name synonym)|uniprotkb:VEGFR1(gene name synonym) psi-mi:p15692-4(display_long)|uniprotkb:VEGF(isoform synonym)|uniprotkb:VEGFA(gene name)|psi-mi:VEGFA(display_short)|uniprotkb:VEGF(gene name synonym)|uniprotkb:Vascular permeability factor(gene name synonym) psi-mi:"MI:0405"(competition binding) de et al. (1992) pubmed:1312256|imex:IM-22104 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9006093|imex:IM-22104-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153392.1|refseq:NP_002010.2|ensembl:ENSG00000102755(gene)|ensembl:ENST00000282397(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036323"(vascular endothelial growth factor receptor-1 signaling pathway)|go:"GO:0036332"(placental growth factor-activated receptor activity)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009135(Vascular endothelial growth factor receptor 1, VEGFR1, N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|mint:P17948|rcsb pdb:1FLT|rcsb pdb:1QSV|rcsb pdb:1QSZ|rcsb pdb:1QTY|rcsb pdb:1RV6|rcsb pdb:2XAC|rcsb pdb:3HNG|rcsb pdb:4CKV|rcsb pdb:4CL7|rcsb pdb:5ABD|rcsb pdb:5EX3|rcsb pdb:5T89|reactome:R-HSA-194306|reactome:R-HSA-195399|interpro:IPR041348|refseq:NP_001153502.1|refseq:NP_001153503.1|dip:DIP-643N intact:EBI-1026643(vegfa_human)|ensembl:ENSG00000112715(gene)|ensembl:ENST00000523950(transcript) - - - figure legend:Fig.2|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2014/10/16 rogid:AfSO/WFuXISaK/PbB/s2Vv+vLFE9606 rogid:/DdgEEe0/rYnemiYvqxeQ+KiXXs9606 intact-crc:8C1DF4309E3D2684|rigid:cs5mJ/dDnmfnmsXcWmIPcgD1Zt0 false - 125i radiolabel:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P17948 uniprotkb:P15692-4 intact:EBI-1026718|uniprotkb:B0LPF1|uniprotkb:B3FR89|uniprotkb:B5A923|uniprotkb:O60722|uniprotkb:P16057|uniprotkb:Q12954|uniprotkb:A8KA71|ensembl:ENSP00000282397|uniprotkb:A3E342|uniprotkb:A3E344|uniprotkb:B2BF46|uniprotkb:B2BF47|uniprotkb:F5H5L6|uniprotkb:B2BF48 intact:EBI-1026691|ensembl:ENSP00000429643 psi-mi:vgfr1_human(display_long)|uniprotkb:Vascular permeability factor receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor FLT(gene name synonym)|uniprotkb:Tyrosine-protein kinase FRT(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 1(gene name synonym)|uniprotkb:FLT1(gene name)|psi-mi:FLT1(display_short)|uniprotkb:FLT(gene name synonym)|uniprotkb:FRT(gene name synonym)|uniprotkb:VEGFR1(gene name synonym) psi-mi:p15692-4(display_long)|uniprotkb:VEGF(isoform synonym)|uniprotkb:VEGFA(gene name)|psi-mi:VEGFA(display_short)|uniprotkb:VEGF(gene name synonym)|uniprotkb:Vascular permeability factor(gene name synonym) psi-mi:"MI:0030"(cross-linking study) de et al. (1992) pubmed:1312256|imex:IM-22104 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9006223|imex:IM-22104-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153392.1|refseq:NP_002010.2|ensembl:ENSG00000102755(gene)|ensembl:ENST00000282397(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036323"(vascular endothelial growth factor receptor-1 signaling pathway)|go:"GO:0036332"(placental growth factor-activated receptor activity)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009135(Vascular endothelial growth factor receptor 1, VEGFR1, N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|mint:P17948|rcsb pdb:1FLT|rcsb pdb:1QSV|rcsb pdb:1QSZ|rcsb pdb:1QTY|rcsb pdb:1RV6|rcsb pdb:2XAC|rcsb pdb:3HNG|rcsb pdb:4CKV|rcsb pdb:4CL7|rcsb pdb:5ABD|rcsb pdb:5EX3|rcsb pdb:5T89|reactome:R-HSA-194306|reactome:R-HSA-195399|interpro:IPR041348|refseq:NP_001153502.1|refseq:NP_001153503.1|dip:DIP-643N intact:EBI-1026643(vegfa_human)|ensembl:ENSG00000112715(gene)|ensembl:ENST00000523950(transcript) - - - figure legend:Fig. 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2014/10/16 rogid:AfSO/WFuXISaK/PbB/s2Vv+vLFE9606 rogid:/DdgEEe0/rYnemiYvqxeQ+KiXXs9606 intact-crc:4F2E4B71E0F5F05F|rigid:cs5mJ/dDnmfnmsXcWmIPcgD1Zt0 false - 125i radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P15692-4 uniprotkb:P15692-4 intact:EBI-1026691|ensembl:ENSP00000429643 intact:EBI-1026691|ensembl:ENSP00000429643 psi-mi:p15692-4(display_long)|uniprotkb:VEGF(isoform synonym)|uniprotkb:VEGFA(gene name)|psi-mi:VEGFA(display_short)|uniprotkb:VEGF(gene name synonym)|uniprotkb:Vascular permeability factor(gene name synonym) psi-mi:p15692-4(display_long)|uniprotkb:VEGF(isoform synonym)|uniprotkb:VEGFA(gene name)|psi-mi:VEGFA(display_short)|uniprotkb:VEGF(gene name synonym)|uniprotkb:Vascular permeability factor(gene name synonym) psi-mi:"MI:0030"(cross-linking study) de et al. (1992) pubmed:1312256|imex:IM-22104 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9006656|imex:IM-22104-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1026643(vegfa_human)|ensembl:ENSG00000112715(gene)|ensembl:ENST00000523950(transcript) intact:EBI-1026643(vegfa_human)|ensembl:ENSG00000112715(gene)|ensembl:ENST00000523950(transcript) - - - figure legend:Fig. 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2014/10/16 rogid:/DdgEEe0/rYnemiYvqxeQ+KiXXs9606 rogid:/DdgEEe0/rYnemiYvqxeQ+KiXXs9606 intact-crc:C7B8B47CA974B111|rigid:cs5mJ/dDnmfnmsXcWmIPcgD1Zt0 false 125i radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P15692-4 uniprotkb:P17948 intact:EBI-1026691|ensembl:ENSP00000429643 intact:EBI-1026718|uniprotkb:B0LPF1|uniprotkb:B3FR89|uniprotkb:B5A923|uniprotkb:O60722|uniprotkb:P16057|uniprotkb:Q12954|uniprotkb:A8KA71|ensembl:ENSP00000282397|uniprotkb:A3E342|uniprotkb:A3E344|uniprotkb:B2BF46|uniprotkb:B2BF47|uniprotkb:F5H5L6|uniprotkb:B2BF48 psi-mi:p15692-4(display_long)|uniprotkb:VEGF(isoform synonym)|uniprotkb:VEGFA(gene name)|psi-mi:VEGFA(display_short)|uniprotkb:VEGF(gene name synonym)|uniprotkb:Vascular permeability factor(gene name synonym) psi-mi:vgfr1_human(display_long)|uniprotkb:Vascular permeability factor receptor(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor FLT(gene name synonym)|uniprotkb:Tyrosine-protein kinase FRT(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 1(gene name synonym)|uniprotkb:FLT1(gene name)|psi-mi:FLT1(display_short)|uniprotkb:FLT(gene name synonym)|uniprotkb:FRT(gene name synonym)|uniprotkb:VEGFR1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) de et al. (1992) pubmed:1312256|imex:IM-22104 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-9006656|imex:IM-22104-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1026643(vegfa_human)|ensembl:ENSG00000112715(gene)|ensembl:ENST00000523950(transcript) refseq:NP_001153392.1|refseq:NP_002010.2|ensembl:ENSG00000102755(gene)|ensembl:ENST00000282397(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005021"(vascular endothelial growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036323"(vascular endothelial growth factor receptor-1 signaling pathway)|go:"GO:0036332"(placental growth factor-activated receptor activity)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009135(Vascular endothelial growth factor receptor 1, VEGFR1, N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036179|mint:P17948|rcsb pdb:1FLT|rcsb pdb:1QSV|rcsb pdb:1QSZ|rcsb pdb:1QTY|rcsb pdb:1RV6|rcsb pdb:2XAC|rcsb pdb:3HNG|rcsb pdb:4CKV|rcsb pdb:4CL7|rcsb pdb:5ABD|rcsb pdb:5EX3|rcsb pdb:5T89|reactome:R-HSA-194306|reactome:R-HSA-195399|interpro:IPR041348|refseq:NP_001153502.1|refseq:NP_001153503.1|dip:DIP-643N - - - figure legend:Fig. 3|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/12/03 2014/10/16 rogid:/DdgEEe0/rYnemiYvqxeQ+KiXXs9606 rogid:AfSO/WFuXISaK/PbB/s2Vv+vLFE9606 intact-crc:C7B8B47CA974B111|rigid:cs5mJ/dDnmfnmsXcWmIPcgD1Zt0 false 125i radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)