#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:16810"	chebi:"CHEBI:22651"	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-8789006	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:ascorbate(display_short)|psi-mi:"CHEBI:22651"(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	O'Brien et al. (2003)	pubmed:12741810|imex:IM-21536	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8789005|wwpdb:1otj|imex:IM-21536-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	3d-r-factors:R = 0.22; Rwork = 0.21; Rfree = 0.25|3d-resolution:1.9 A|figure legend:Fig.s 2, 5|comment:The full asymmetrical structure is thought to be a homotetramer with three TauD-taurine bound monomers and one open TauD monomer. PISA modeling in PDB suggests dimers may also be possible.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/07	2014/10/16	-	-	intact-crc:3322A30663FD0374	false	-	-	4	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	chebi:"CHEBI:29033"	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-2929936	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:iron2plus(display_short)|psi-mi:"CHEBI:29033"(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	O'Brien et al. (2003)	pubmed:12741810|imex:IM-21536	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8789005|wwpdb:1otj|imex:IM-21536-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	3d-r-factors:R = 0.22; Rwork = 0.21; Rfree = 0.25|3d-resolution:1.9 A|figure legend:Fig.s 2, 5|comment:The full asymmetrical structure is thought to be a homotetramer with three TauD-taurine bound monomers and one open TauD monomer. PISA modeling in PDB suggests dimers may also be possible.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/07	2014/10/16	-	-	intact-crc:3322A30663FD0374	false	-	-	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	uniprotkb:P37610	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-1116170|uniprotkb:P77797|uniprotkb:Q2MC57|uniprotkb:Q47540|ensemblbacteria:AAC73471|ensemblbacteria:BAE76149	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:taud_ecoli(display_long)|uniprotkb:yaiG(gene name synonym)|uniprotkb:2-aminoethanesulfonate dioxygenase(gene name synonym)|uniprotkb:tauD(gene name)|psi-mi:tauD(display_short)|uniprotkb:ssiD(gene name synonym)|uniprotkb:b0368(locus name)|uniprotkb:JW0360(locus name)|uniprotkb:Sulfate starvation-induced protein 3(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	O'Brien et al. (2003)	pubmed:12741810|imex:IM-21536	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8789005|wwpdb:1otj|imex:IM-21536-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_414902.1|ensemblbacteria:AAC73471(transcript)|ensemblbacteria:b0368(gene)|ensemblbacteria:BAE76149(gene)|ensemblbacteria:BAE76149(transcript)|go:"GO:0000908"(taurine dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990205"(taurine dioxygenase complex)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR042098|rcsb pdb:1GQW|rcsb pdb:1GY9|rcsb pdb:1OS7|rcsb pdb:1OTJ|rcsb pdb:6EDH|refseq:WP_000004027.1|dip:DIP-10966N	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	-	3d-r-factors:R = 0.22; Rwork = 0.21; Rfree = 0.25|3d-resolution:1.9 A|figure legend:Fig.s 2, 5|comment:The full asymmetrical structure is thought to be a homotetramer with three TauD-taurine bound monomers and one open TauD monomer. PISA modeling in PDB suggests dimers may also be possible.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/07	2014/10/16	-	rogid:RyZHCdTYwnfUiLU45pNScj+gDVU83333	intact-crc:3322A30663FD0374	false	-	his tag:n-n	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16810"	chebi:"CHEBI:15891"	intact:EBI-8789008|chebi:"CHEBI:11638"|chebi:"CHEBI:19748"	intact:EBI-8789020|chebi:"CHEBI:45877"|chebi:"CHEBI:9406"|chebi:"CHEBI:15195"|chebi:"CHEBI:26852"	psi-mi:"2-oxoglutarate(2-)"(display_short)|psi-mi:"CHEBI:16810"(display_long)|intact:2-ketoglutarate(synonym)|intact:2-oxoglutarate(synonym)|intact:"2-oxopentanedioic acid, ion(2-)"(synonym)|intact:alpha-ketoglutarate(synonym)|intact:2-oxopentanedioate(iupac name)	psi-mi:taurine(display_short)|psi-mi:"CHEBI:15891"(display_long)|intact:2-Aminoethanesulfonic acid(synonym)|intact:2-aminoethyl sulfonate(synonym)|intact:Aminoethylsulfonic acid(synonym)|intact:beta-aminoethylsulfonic acid(synonym)|intact:Taurine(synonym)|intact:2-aminoethanesulfonic acid(iupac name)	psi-mi:"MI:0114"(x-ray crystallography)	O'Brien et al. (2003)	pubmed:12741810|imex:IM-21536	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8789005|wwpdb:1otj|imex:IM-21536-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	inchi key:KPGXRSRHYNQIFN-UHFFFAOYSA-L	inchi key:XOAAWQZATWQOTB-UHFFFAOYSA-N	3d-r-factors:R = 0.22; Rwork = 0.21; Rfree = 0.25|3d-resolution:1.9 A|figure legend:Fig.s 2, 5|comment:The full asymmetrical structure is thought to be a homotetramer with three TauD-taurine bound monomers and one open TauD monomer. PISA modeling in PDB suggests dimers may also be possible.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/07	2014/10/16	-	-	intact-crc:3322A30663FD0374	false	-	-	4	3	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15891"	uniprotkb:P37610	intact:EBI-8789020|chebi:"CHEBI:45877"|chebi:"CHEBI:9406"|chebi:"CHEBI:15195"|chebi:"CHEBI:26852"	intact:EBI-1116170|uniprotkb:P77797|uniprotkb:Q2MC57|uniprotkb:Q47540|ensemblbacteria:AAC73471|ensemblbacteria:BAE76149	psi-mi:taurine(display_short)|psi-mi:"CHEBI:15891"(display_long)|intact:2-Aminoethanesulfonic acid(synonym)|intact:2-aminoethyl sulfonate(synonym)|intact:Aminoethylsulfonic acid(synonym)|intact:beta-aminoethylsulfonic acid(synonym)|intact:Taurine(synonym)|intact:2-aminoethanesulfonic acid(iupac name)	psi-mi:taud_ecoli(display_long)|uniprotkb:yaiG(gene name synonym)|uniprotkb:2-aminoethanesulfonate dioxygenase(gene name synonym)|uniprotkb:tauD(gene name)|psi-mi:tauD(display_short)|uniprotkb:ssiD(gene name synonym)|uniprotkb:b0368(locus name)|uniprotkb:JW0360(locus name)|uniprotkb:Sulfate starvation-induced protein 3(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	O'Brien et al. (2003)	pubmed:12741810|imex:IM-21536	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8789145|wwpdb:1os7|imex:IM-21536-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_414902.1|ensemblbacteria:AAC73471(transcript)|ensemblbacteria:b0368(gene)|ensemblbacteria:BAE76149(gene)|ensemblbacteria:BAE76149(transcript)|go:"GO:0000908"(taurine dioxygenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006790"(sulfur compound metabolic process)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990205"(taurine dioxygenase complex)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR042098|rcsb pdb:1GQW|rcsb pdb:1GY9|rcsb pdb:1OS7|rcsb pdb:1OTJ|rcsb pdb:6EDH|refseq:WP_000004027.1|dip:DIP-10966N	-	inchi key:XOAAWQZATWQOTB-UHFFFAOYSA-N	-	3d-r-factors:R = 0.23; Rwork = 0.22; Rfree = 0.28|3d-resolution:2.5 A|figure legend:Fig.s 3, 4|comment:The full asymmetrical structure is thought to be a homotetramer with three TauD-taurine bound monomers and one open TauD monomer. PISA modeling in PDB suggests dimers may also be possible.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/07	2019/01/30	-	rogid:RyZHCdTYwnfUiLU45pNScj+gDVU83333	intact-crc:6A9952B63374ABC6	false	-	his tag:n-n	3	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)