#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43406	uniprotkb:Q8VI36	intact:EBI-6598977|ensembl:ENSMUSP00000028499|uniprotkb:A2AKI6	intact:EBI-983394|uniprotkb:Q3TB62|uniprotkb:Q3TZQ6|uniprotkb:Q8VI37	psi-mi:itav_mouse(display_long)|uniprotkb:Itgav(gene name)|psi-mi:Itgav(display_short)|uniprotkb:Vitronectin receptor subunit alpha(gene name synonym)	psi-mi:paxi_mouse(display_long)|uniprotkb:Pxn(gene name)|psi-mi:Pxn(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	von et al. (2003)	imex:IM-18861|pubmed:12682088|mint:MINT-8312164	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6597515|imex:IM-18861-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000027087(gene)|ensembl:ENSMUST00000028499(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009566"(fertilization)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019960"(C-X3-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032490"(detection of molecule of bacterial origin)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034685"(integrin alphav-beta6 complex)|go:"GO:0034686"(integrin alphav-beta8 complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0038132"(neuregulin binding)|go:"GO:0042110"(T cell activation)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050748"(negative regulation of lipoprotein metabolic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071604"(transforming growth factor beta production)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1901388"(regulation of transforming growth factor beta activation)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|go:"GO:1990430"(extracellular matrix protein binding)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P43406|reactome:R-MMU-1236973|reactome:R-MMU-1566948|reactome:R-MMU-210990|reactome:R-MMU-2129379|reactome:R-MMU-216083|reactome:R-MMU-3000170|reactome:R-MMU-3000178|reactome:R-MMU-4420097|go:"GO:0034684"(integrin alphav-beta5 complex)|reactome:R-MMU-445144|reactome:R-MMU-6798695|refseq:NP_032428.2	refseq:NP_598676.2|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017166"(vinculin binding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0038191"(neuropilin binding)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051435"(BH4 domain binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:1901652"(response to peptide)|rcsb pdb:5W93|rcsb pdb:6JMU|reactome:R-MMU-180292|reactome:R-MMU-4420097|reactome:R-MMU-445355|reactome:R-MMU-446343|reactome:R-MMU-446388|reactome:R-MMU-8849471|refseq:NP_035353.1|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q8VI36|interpro:IPR001904(Paxillin)	go:"GO:0031252"(cell leading edge)	-	-	figure legend:"Fig 2A (e, o)."|comment:"RPTP-alpha, integrin alpha-V and paxillin colocalized at the leading edge at 30 min after cell spreading on both fibronectin and vitronectin surfaces [Fig 2A (e,o)]. RPTP-alpha did not colocalize with integrin alpha-V or paxillin, at 240 min after cell spreading on either fibronectin or vitronectin surfaces [Fig 2A(h,r)], whereas integrin alpha-V and paxillin remained colocalized at focal contacts [Fig 2A (j,t)]."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2013/04/03	2014/10/16	rogid:gXXEM3W1KZEAcURvaHkTBb7Skwg10090	rogid:x972uTduA/N0V3wYShfP138d6Sk10090	intact-crc:24F0DB82BCDDE571|rigid:lElR0TqMpJvkYYEBNIlVSjNM8ug	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P43406	uniprotkb:P18052	intact:EBI-6598977|ensembl:ENSMUSP00000028499|uniprotkb:A2AKI6	intact:EBI-6597520|ensembl:ENSMUSP00000076533|uniprotkb:A2AHF2|uniprotkb:Q61808	psi-mi:itav_mouse(display_long)|uniprotkb:Itgav(gene name)|psi-mi:Itgav(display_short)|uniprotkb:Vitronectin receptor subunit alpha(gene name synonym)	psi-mi:ptpra_mouse(display_long)|uniprotkb:Ptpra(gene name)|psi-mi:Ptpra(display_short)|uniprotkb:Lrp(gene name synonym)|uniprotkb:Ptpa(gene name synonym)|uniprotkb:LCA-related phosphatase(gene name synonym)|uniprotkb:PTPTY-28(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	von et al. (2003)	imex:IM-18861|pubmed:12682088|mint:MINT-8312164	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6597515|imex:IM-18861-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000027087(gene)|ensembl:ENSMUST00000028499(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009566"(fertilization)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019960"(C-X3-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032490"(detection of molecule of bacterial origin)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034685"(integrin alphav-beta6 complex)|go:"GO:0034686"(integrin alphav-beta8 complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0038132"(neuregulin binding)|go:"GO:0042110"(T cell activation)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050748"(negative regulation of lipoprotein metabolic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071604"(transforming growth factor beta production)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1901388"(regulation of transforming growth factor beta activation)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|go:"GO:1990430"(extracellular matrix protein binding)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P43406|reactome:R-MMU-1236973|reactome:R-MMU-1566948|reactome:R-MMU-210990|reactome:R-MMU-2129379|reactome:R-MMU-216083|reactome:R-MMU-3000170|reactome:R-MMU-3000178|reactome:R-MMU-4420097|go:"GO:0034684"(integrin alphav-beta5 complex)|reactome:R-MMU-445144|reactome:R-MMU-6798695|refseq:NP_032428.2	ensembl:ENSMUSG00000027303(gene)|ensembl:ENSMUST00000077303(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|rcsb pdb:1P15|rcsb pdb:1YFO|reactome:R-MMU-375165|reactome:R-MMU-5673001|mint:P18052|refseq:NP_033006.2	go:"GO:0031252"(cell leading edge)	-	-	figure legend:"Fig 2A (e, o)."|comment:"RPTP-alpha, integrin alpha-V and paxillin colocalized at the leading edge at 30 min after cell spreading on both fibronectin and vitronectin surfaces [Fig 2A (e,o)]. RPTP-alpha did not colocalize with integrin alpha-V or paxillin, at 240 min after cell spreading on either fibronectin or vitronectin surfaces [Fig 2A(h,r)], whereas integrin alpha-V and paxillin remained colocalized at focal contacts [Fig 2A (j,t)]."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2013/04/03	2014/10/16	rogid:gXXEM3W1KZEAcURvaHkTBb7Skwg10090	rogid:2OLnRSJvcMrmaAF1Jw9t/tpt/L410090	intact-crc:24F0DB82BCDDE571|rigid:lElR0TqMpJvkYYEBNIlVSjNM8ug	false	-	yellow fluorescent protein tag:c-c|sufficient binding region:1-516	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P18052	uniprotkb:P43406	intact:EBI-6597520|ensembl:ENSMUSP00000076533|uniprotkb:A2AHF2|uniprotkb:Q61808	intact:EBI-6598977|ensembl:ENSMUSP00000028499|uniprotkb:A2AKI6	psi-mi:ptpra_mouse(display_long)|uniprotkb:Ptpra(gene name)|psi-mi:Ptpra(display_short)|uniprotkb:Lrp(gene name synonym)|uniprotkb:Ptpa(gene name synonym)|uniprotkb:LCA-related phosphatase(gene name synonym)|uniprotkb:PTPTY-28(gene name synonym)	psi-mi:itav_mouse(display_long)|uniprotkb:Itgav(gene name)|psi-mi:Itgav(display_short)|uniprotkb:Vitronectin receptor subunit alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	von et al. (2003)	imex:IM-18861|pubmed:12682088|mint:MINT-8312164	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6599037|imex:IM-18861-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000027303(gene)|ensembl:ENSMUST00000077303(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|rcsb pdb:1P15|rcsb pdb:1YFO|reactome:R-MMU-375165|reactome:R-MMU-5673001|mint:P18052|refseq:NP_033006.2	ensembl:ENSMUSG00000027087(gene)|ensembl:ENSMUST00000028499(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009566"(fertilization)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019960"(C-X3-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032490"(detection of molecule of bacterial origin)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034685"(integrin alphav-beta6 complex)|go:"GO:0034686"(integrin alphav-beta8 complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0035867"(alphav-beta3 integrin-IGF-1-IGF1R complex)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0038132"(neuregulin binding)|go:"GO:0042110"(T cell activation)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050748"(negative regulation of lipoprotein metabolic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071604"(transforming growth factor beta production)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1901388"(regulation of transforming growth factor beta activation)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|go:"GO:1990430"(extracellular matrix protein binding)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P43406|reactome:R-MMU-1236973|reactome:R-MMU-1566948|reactome:R-MMU-210990|reactome:R-MMU-2129379|reactome:R-MMU-216083|reactome:R-MMU-3000170|reactome:R-MMU-3000178|reactome:R-MMU-4420097|go:"GO:0034684"(integrin alphav-beta5 complex)|reactome:R-MMU-445144|reactome:R-MMU-6798695|refseq:NP_032428.2	-	-	-	figure legend:Fig 3A.|comment:RPTP-alpha co-precipitated with integrin alpha-V  in fibroblasts, 15 minutes after spreading on both fibronectin and vitronectin. RPTP-alpha did not co-precipitate with integrin alpha-V , at 15 min after the fibroblasts were spread on fibronectin, but treated with GPen. RPTP-alpha did not co-precipitate with integrin alpha-V, at 240 min after the fibroblasts were spread on fibronectin. RPTP-alpha did not co-precipitate with integrin alpha-V, in fibroblast cells in suspension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2013/04/03	2014/10/16	rogid:2OLnRSJvcMrmaAF1Jw9t/tpt/L410090	rogid:gXXEM3W1KZEAcURvaHkTBb7Skwg10090	intact-crc:AA44B77C689DEEB4|rigid:nqV9onj8A/9NZxJaxoADM3Ah0SQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)