#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9QUI1 uniprotkb:P12755 intact:EBI-6503100|ensembl:ENSMUSP00000097538|uniprotkb:Q8K2S5|uniprotkb:Q9JHD8|uniprotkb:Q9JL54 intact:EBI-347281|uniprotkb:Q5SYT7|ensembl:ENSP00000367797 psi-mi:lra25_mouse(display_long)|uniprotkb:Fam89b(gene name)|psi-mi:Fam89b(display_short)|uniprotkb:Mtvr2(gene name synonym)|uniprotkb:C184L ORF2 protein(gene name synonym)|uniprotkb:C184M protein(gene name synonym)|uniprotkb:C184m(gene name synonym)|uniprotkb:MMTV receptor(gene name synonym)|uniprotkb:Lrap25(gene name synonym) psi-mi:ski_human(display_long)|uniprotkb:SKI(gene name)|psi-mi:SKI(display_short)|uniprotkb:Proto-oncogene c-Ski(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kokura et al. (2003) pubmed:12646588 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852117.2|ensembl:ENSMUST00000099955(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|interpro:IPR039499|ensembl:ENSMUSG00000024939(gene) refseq:NP_003027.1|ensembl:ENSG00000157933(gene)|ensembl:ENST00000378536(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028760|interpro:IPR037000|rcsb pdb:1MR1|rcsb pdb:1SBX|rcsb pdb:5XOD|rcsb pdb:6ZVQ|reactome:R-HSA-201451|reactome:R-HSA-2173795|dip:DIP-31514N - - - figure legend:no figure|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/01/24 2014/10/16 rogid:V36rCHIbelYmcn6H3UO72UqT32410090 rogid:4B7ntPUjNTh9UjjFHW6PoLUnxCM9606 intact-crc:1740CE18C49A2422|rigid:CLRoUkWUhF56JTE2PbUIwbN9yUA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9QUI1 uniprotkb:P12755 intact:EBI-6503100|ensembl:ENSMUSP00000097538|uniprotkb:Q8K2S5|uniprotkb:Q9JHD8|uniprotkb:Q9JL54 intact:EBI-347281|uniprotkb:Q5SYT7|ensembl:ENSP00000367797 psi-mi:lra25_mouse(display_long)|uniprotkb:Fam89b(gene name)|psi-mi:Fam89b(display_short)|uniprotkb:Mtvr2(gene name synonym)|uniprotkb:C184L ORF2 protein(gene name synonym)|uniprotkb:C184M protein(gene name synonym)|uniprotkb:C184m(gene name synonym)|uniprotkb:MMTV receptor(gene name synonym)|uniprotkb:Lrap25(gene name synonym) psi-mi:ski_human(display_long)|uniprotkb:SKI(gene name)|psi-mi:SKI(display_short)|uniprotkb:Proto-oncogene c-Ski(gene name synonym) psi-mi:"MI:0096"(pull down) Kokura et al. (2003) pubmed:12646588 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852117.2|ensembl:ENSMUST00000099955(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|interpro:IPR039499|ensembl:ENSMUSG00000024939(gene) refseq:NP_003027.1|ensembl:ENSG00000157933(gene)|ensembl:ENST00000378536(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028760|interpro:IPR037000|rcsb pdb:1MR1|rcsb pdb:1SBX|rcsb pdb:5XOD|rcsb pdb:6ZVQ|reactome:R-HSA-201451|reactome:R-HSA-2173795|dip:DIP-31514N - - - figure legend:1B and D|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/24 2014/10/16 rogid:V36rCHIbelYmcn6H3UO72UqT32410090 rogid:4B7ntPUjNTh9UjjFHW6PoLUnxCM9606 intact-crc:66B607612233F81D|rigid:CLRoUkWUhF56JTE2PbUIwbN9yUA false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P12755 uniprotkb:Q9QUI1 intact:EBI-347281|uniprotkb:Q5SYT7|ensembl:ENSP00000367797 intact:EBI-6503100|ensembl:ENSMUSP00000097538|uniprotkb:Q8K2S5|uniprotkb:Q9JHD8|uniprotkb:Q9JL54 psi-mi:ski_human(display_long)|uniprotkb:SKI(gene name)|psi-mi:SKI(display_short)|uniprotkb:Proto-oncogene c-Ski(gene name synonym) psi-mi:lra25_mouse(display_long)|uniprotkb:Fam89b(gene name)|psi-mi:Fam89b(display_short)|uniprotkb:Mtvr2(gene name synonym)|uniprotkb:C184L ORF2 protein(gene name synonym)|uniprotkb:C184M protein(gene name synonym)|uniprotkb:C184m(gene name synonym)|uniprotkb:MMTV receptor(gene name synonym)|uniprotkb:Lrap25(gene name synonym) psi-mi:"MI:0096"(pull down) Kokura et al. (2003) pubmed:12646588 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003027.1|ensembl:ENSG00000157933(gene)|ensembl:ENST00000378536(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028760|interpro:IPR037000|rcsb pdb:1MR1|rcsb pdb:1SBX|rcsb pdb:5XOD|rcsb pdb:6ZVQ|reactome:R-HSA-201451|reactome:R-HSA-2173795|dip:DIP-31514N refseq:NP_852117.2|ensembl:ENSMUST00000099955(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|interpro:IPR039499|ensembl:ENSMUSG00000024939(gene) - - - figure legend:2A and C|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/24 2014/10/16 rogid:4B7ntPUjNTh9UjjFHW6PoLUnxCM9606 rogid:V36rCHIbelYmcn6H3UO72UqT32410090 intact-crc:BCDE77B50FF4E46B|rigid:CLRoUkWUhF56JTE2PbUIwbN9yUA false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9QUI1 uniprotkb:P12755 intact:EBI-6503100|ensembl:ENSMUSP00000097538|uniprotkb:Q8K2S5|uniprotkb:Q9JHD8|uniprotkb:Q9JL54 intact:EBI-347281|uniprotkb:Q5SYT7|ensembl:ENSP00000367797 psi-mi:lra25_mouse(display_long)|uniprotkb:Fam89b(gene name)|psi-mi:Fam89b(display_short)|uniprotkb:Mtvr2(gene name synonym)|uniprotkb:C184L ORF2 protein(gene name synonym)|uniprotkb:C184M protein(gene name synonym)|uniprotkb:C184m(gene name synonym)|uniprotkb:MMTV receptor(gene name synonym)|uniprotkb:Lrap25(gene name synonym) psi-mi:ski_human(display_long)|uniprotkb:SKI(gene name)|psi-mi:SKI(display_short)|uniprotkb:Proto-oncogene c-Ski(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kokura et al. (2003) pubmed:12646588 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852117.2|ensembl:ENSMUST00000099955(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|interpro:IPR039499|ensembl:ENSMUSG00000024939(gene) refseq:NP_003027.1|ensembl:ENSG00000157933(gene)|ensembl:ENST00000378536(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028760|interpro:IPR037000|rcsb pdb:1MR1|rcsb pdb:1SBX|rcsb pdb:5XOD|rcsb pdb:6ZVQ|reactome:R-HSA-201451|reactome:R-HSA-2173795|dip:DIP-31514N - - - figure legend:3A|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/01/24 2014/10/16 rogid:V36rCHIbelYmcn6H3UO72UqT32410090 rogid:4B7ntPUjNTh9UjjFHW6PoLUnxCM9606 intact-crc:74648B211872C916|rigid:CLRoUkWUhF56JTE2PbUIwbN9yUA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P12755 uniprotkb:Q9QUI1 intact:EBI-347281|uniprotkb:Q5SYT7|ensembl:ENSP00000367797 intact:EBI-6503100|ensembl:ENSMUSP00000097538|uniprotkb:Q8K2S5|uniprotkb:Q9JHD8|uniprotkb:Q9JL54 psi-mi:ski_human(display_long)|uniprotkb:SKI(gene name)|psi-mi:SKI(display_short)|uniprotkb:Proto-oncogene c-Ski(gene name synonym) psi-mi:lra25_mouse(display_long)|uniprotkb:Fam89b(gene name)|psi-mi:Fam89b(display_short)|uniprotkb:Mtvr2(gene name synonym)|uniprotkb:C184L ORF2 protein(gene name synonym)|uniprotkb:C184M protein(gene name synonym)|uniprotkb:C184m(gene name synonym)|uniprotkb:MMTV receptor(gene name synonym)|uniprotkb:Lrap25(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kokura et al. (2003) pubmed:12646588 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6503219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003027.1|ensembl:ENSG00000157933(gene)|ensembl:ENST00000378536(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028760|interpro:IPR037000|rcsb pdb:1MR1|rcsb pdb:1SBX|rcsb pdb:5XOD|rcsb pdb:6ZVQ|reactome:R-HSA-201451|reactome:R-HSA-2173795|dip:DIP-31514N refseq:NP_852117.2|ensembl:ENSMUST00000099955(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|interpro:IPR039499|ensembl:ENSMUSG00000024939(gene) - - - figure legend:3B|curation depth:mimix curation taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast) - 2013/01/24 2014/10/16 rogid:4B7ntPUjNTh9UjjFHW6PoLUnxCM9606 rogid:V36rCHIbelYmcn6H3UO72UqT32410090 intact-crc:52BED9D442E3A5D2|rigid:CLRoUkWUhF56JTE2PbUIwbN9yUA false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9QUI1 uniprotkb:P12755 intact:EBI-6503100|ensembl:ENSMUSP00000097538|uniprotkb:Q8K2S5|uniprotkb:Q9JHD8|uniprotkb:Q9JL54 intact:EBI-347281|uniprotkb:Q5SYT7|ensembl:ENSP00000367797 psi-mi:lra25_mouse(display_long)|uniprotkb:Fam89b(gene name)|psi-mi:Fam89b(display_short)|uniprotkb:Mtvr2(gene name synonym)|uniprotkb:C184L ORF2 protein(gene name synonym)|uniprotkb:C184M protein(gene name synonym)|uniprotkb:C184m(gene name synonym)|uniprotkb:MMTV receptor(gene name synonym)|uniprotkb:Lrap25(gene name synonym) psi-mi:ski_human(display_long)|uniprotkb:SKI(gene name)|psi-mi:SKI(display_short)|uniprotkb:Proto-oncogene c-Ski(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kokura et al. (2003) pubmed:12646588 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852117.2|ensembl:ENSMUST00000099955(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|interpro:IPR039499|ensembl:ENSMUSG00000024939(gene) refseq:NP_003027.1|ensembl:ENSG00000157933(gene)|ensembl:ENST00000378536(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046811"(histone deacetylase inhibitor activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR010919(SAND-like)|interpro:IPR014890(c-SKI Smad4 binding)|interpro:IPR023216|interpro:IPR028760|interpro:IPR037000|rcsb pdb:1MR1|rcsb pdb:1SBX|rcsb pdb:5XOD|rcsb pdb:6ZVQ|reactome:R-HSA-201451|reactome:R-HSA-2173795|dip:DIP-31514N - - - figure legend:3B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/01/24 2014/10/16 rogid:V36rCHIbelYmcn6H3UO72UqT32410090 rogid:4B7ntPUjNTh9UjjFHW6PoLUnxCM9606 intact-crc:E80286EA8415A821|rigid:CLRoUkWUhF56JTE2PbUIwbN9yUA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)