#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9ERE7 uniprotkb:O88572 intact:EBI-6662606|ensembl:ENSMUSP00000091768|uniprotkb:Q8C611|uniprotkb:Q8CCX7|uniprotkb:Q91WK8|uniprotkb:Q9CVB9 intact:EBI-6169857 psi-mi:mesd_mouse(display_long)|uniprotkb:Mesd(gene name)|psi-mi:Mesd(display_short)|uniprotkb:LDLR chaperone MESD(gene name synonym)|uniprotkb:Mesdc2(gene name synonym)|uniprotkb:Mesoderm development candidate 2(gene name synonym)|uniprotkb:Mesoderm development protein(gene name synonym) psi-mi:lrp6_mouse(display_long)|uniprotkb:Lrp6(gene name)|psi-mi:Lrp6(display_short) psi-mi:"MI:0663"(confocal microscopy) Hsieh et al. (2003) imex:IM-20535|pubmed:12581525 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-6677952|imex:IM-20535-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038503(gene)|ensembl:ENSMUST00000094215(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006909"(phagocytosis)|go:"GO:0007498"(mesoderm development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR019330|mint:Q9ERE7|rcsb pdb:2I9S|rcsb pdb:2KGL|rcsb pdb:2KMI|rcsb pdb:2RQK|rcsb pdb:2RQM|rcsb pdb:3OFH|refseq:NP_075892.3|dip:DIP-59114N go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051593"(response to folic acid)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060026"(convergent extension)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060284"(regulation of cell development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060596"(mammary placode formation)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0061310"(canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021872"(forebrain generation of neurons)|go:"GO:0021915"(neural tube development)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030917"(midbrain-hindbrain boundary development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035261"(external genitalia morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046849"(bone remodeling)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014029"(neural crest formation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0019534"(toxin transmembrane transporter activity)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021794"(thalamus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:2000164"(negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis)|go:"GO:2000166"(negative regulation of planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:2000168"(negative regulation of planar cell polarity pathway involved in neural tube closure)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR017049(Low density lipoprotein receptor-related protein, 5/6)|interpro:IPR023415|interpro:IPR036055|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071936"(coreceptor activity involved in Wnt signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090244"(Wnt signaling pathway involved in somitogenesis)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0110135"(Norrin signaling pathway)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|go:"GO:2000149"(negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:2000151"(negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:2000162"(negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis)|refseq:NP_032540.2|dip:DIP-46460N|reactome:R-MMU-3772470|reactome:R-MMU-4641262|reactome:R-MMU-4641263 go:"GO:0009986"(cell surface) - - figure legend:6F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2013/05/02 2014/10/16 rogid:8ONvF1cxwse6ed0r9tgfeHj0+Ww10090 rogid:62E3KoylZ2wnvUSiqWjHmW66CvE10090 intact-crc:DE86134F4A8B3E9C|rigid:wKHFHL4ODZOAKYCVBkpRjD17JbU false his tag:c-c|flag tag:?-?|v5 tag:c-c tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q9ERE7 uniprotkb:Q91VN0 intact:EBI-6662606|ensembl:ENSMUSP00000091768|uniprotkb:Q8C611|uniprotkb:Q8CCX7|uniprotkb:Q91WK8|uniprotkb:Q9CVB9 intact:EBI-6662680|ensembl:ENSMUSP00000025856|uniprotkb:E9QQ75|uniprotkb:O88883|uniprotkb:Q9R208 psi-mi:mesd_mouse(display_long)|uniprotkb:Mesd(gene name)|psi-mi:Mesd(display_short)|uniprotkb:LDLR chaperone MESD(gene name synonym)|uniprotkb:Mesdc2(gene name synonym)|uniprotkb:Mesoderm development candidate 2(gene name synonym)|uniprotkb:Mesoderm development protein(gene name synonym) psi-mi:lrp5_mouse(display_long)|uniprotkb:Lrp5(gene name)|psi-mi:Lrp5(display_short)|uniprotkb:Lrp7(gene name synonym)|uniprotkb:Low-density lipoprotein receptor-related protein 7(gene name synonym)|uniprotkb:Lr3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hsieh et al. (2003) imex:IM-20535|pubmed:12581525 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6662678|imex:IM-20535-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038503(gene)|ensembl:ENSMUST00000094215(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006909"(phagocytosis)|go:"GO:0007498"(mesoderm development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR019330|mint:Q9ERE7|rcsb pdb:2I9S|rcsb pdb:2KGL|rcsb pdb:2KMI|rcsb pdb:2RQK|rcsb pdb:2RQM|rcsb pdb:3OFH|refseq:NP_075892.3|dip:DIP-59114N go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060348"(bone development)|go:"GO:0043235"(receptor complex)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:0061304"(retinal blood vessel morphogenesis)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071936"(coreceptor activity involved in Wnt signaling pathway)|go:"GO:0110135"(Norrin signaling pathway)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR017049(Low density lipoprotein receptor-related protein, 5/6)|interpro:IPR023415|interpro:IPR036055|reactome:R-MMU-3772470|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046849"(bone remodeling)|go:"GO:0048539"(bone marrow development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060033"(anatomical structure regression)|ensembl:ENSMUST00000025856(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001944"(vasculature development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002076"(osteoblast development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006007"(glucose catabolic process)|ensembl:ENSMUSG00000024913(gene)|go:"GO:0006897"(endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035426"(extracellular matrix-cell signaling)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042733"(embryonic digit morphogenesis)|refseq:NP_032539.2 - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2013/05/02 2014/10/16 rogid:8ONvF1cxwse6ed0r9tgfeHj0+Ww10090 rogid:sjkxOcWTXsSC85GDdixlr5hsPE810090 intact-crc:D5302A53EDF98A6D|rigid:hF9t8l+fflYvRB+aI80XXjPaKtY false v5 tag:c-c|his tag:c-c|flag tag:?-? tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ERE7 uniprotkb:O88572 intact:EBI-6662606|ensembl:ENSMUSP00000091768|uniprotkb:Q8C611|uniprotkb:Q8CCX7|uniprotkb:Q91WK8|uniprotkb:Q9CVB9 intact:EBI-6169857 psi-mi:mesd_mouse(display_long)|uniprotkb:Mesd(gene name)|psi-mi:Mesd(display_short)|uniprotkb:LDLR chaperone MESD(gene name synonym)|uniprotkb:Mesdc2(gene name synonym)|uniprotkb:Mesoderm development candidate 2(gene name synonym)|uniprotkb:Mesoderm development protein(gene name synonym) psi-mi:lrp6_mouse(display_long)|uniprotkb:Lrp6(gene name)|psi-mi:Lrp6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hsieh et al. (2003) imex:IM-20535|pubmed:12581525 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6662746|imex:IM-20535-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038503(gene)|ensembl:ENSMUST00000094215(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006909"(phagocytosis)|go:"GO:0007498"(mesoderm development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042802"(identical protein binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR019330|mint:Q9ERE7|rcsb pdb:2I9S|rcsb pdb:2KGL|rcsb pdb:2KMI|rcsb pdb:2RQK|rcsb pdb:2RQM|rcsb pdb:3OFH|refseq:NP_075892.3|dip:DIP-59114N go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051593"(response to folic acid)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060026"(convergent extension)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060059"(embryonic retina morphogenesis in camera-type eye)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060284"(regulation of cell development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060596"(mammary placode formation)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0061310"(canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021872"(forebrain generation of neurons)|go:"GO:0021915"(neural tube development)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030917"(midbrain-hindbrain boundary development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035261"(external genitalia morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046849"(bone remodeling)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014029"(neural crest formation)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0019534"(toxin transmembrane transporter activity)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021794"(thalamus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:2000164"(negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis)|go:"GO:2000166"(negative regulation of planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:2000168"(negative regulation of planar cell polarity pathway involved in neural tube closure)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR017049(Low density lipoprotein receptor-related protein, 5/6)|interpro:IPR023415|interpro:IPR036055|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071936"(coreceptor activity involved in Wnt signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090244"(Wnt signaling pathway involved in somitogenesis)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0110135"(Norrin signaling pathway)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|go:"GO:2000149"(negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:2000151"(negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:2000162"(negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis)|refseq:NP_032540.2|dip:DIP-46460N|reactome:R-MMU-3772470|reactome:R-MMU-4641262|reactome:R-MMU-4641263 - - - figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2013/05/02 2014/10/16 rogid:8ONvF1cxwse6ed0r9tgfeHj0+Ww10090 rogid:62E3KoylZ2wnvUSiqWjHmW66CvE10090 intact-crc:8FC239A361DEE13B|rigid:wKHFHL4ODZOAKYCVBkpRjD17JbU false his tag:c-c|v5 tag:c-c|flag tag:?-? tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)