#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0071"(molecular sieving)	Guarné et al. (2002)	pubmed:12379844|imex:IM-20594	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671578|imex:IM-20594-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 1b|comment:"Tetramer present when SeqA in low concentration or in 5% (v/v) isopropanol. Otherwise forms larger homo-multimers."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:7352D87809C03738|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	sufficient binding region:51-181	sufficient binding region:51-181	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFY8	uniprotkb:P0AFY8	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0030"(cross-linking study)	Guarné et al. (2002)	pubmed:12379844|imex:IM-20594	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671604|imex:IM-20594-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	crc64:37D9078CA3D7229B	crc64:37D9078CA3D7229B	figure legend:Fig. 1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:45CFC23DB6E8BE82|rigid:syFRgJK2kjXv3CXF2C1q/LYz+O4	false	sufficient binding region:51-181	sufficient binding region:51-181	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
intact:EBI-6671633	intact:EBI-6675502	-	-	psi-mi:hemimeth_dna_forw(display_short)|psi-mi:EBI-6671633(display_long)	psi-mi:hemimeth_dna_rev(display_short)|psi-mi:EBI-6675502(display_long)	psi-mi:"MI:0028"(cosedimentation in solution)	Guarné et al. (2002)	pubmed:12379844|imex:IM-20594	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671630|imex:IM-20594-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	pubmed:12379844(primary-reference)	pubmed:12379844(primary-reference)	-	-	-	figure legend:Fig. 1d|comment:Reverse DNA oligo is methylated on Adenine6.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.0x10^-6(molar)	2013/05/10	2014/10/16	-	-	intact-crc:A6366D0AED79E3C6	false	binding-associated region:1-12	binding-associated region:1-14	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-6671633	uniprotkb:P0AFY8	-	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:hemimeth_dna_forw(display_short)|psi-mi:EBI-6671633(display_long)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Guarné et al. (2002)	pubmed:12379844|imex:IM-20594	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671630|imex:IM-20594-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	pubmed:12379844(primary-reference)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	-	crc64:37D9078CA3D7229B	figure legend:Fig. 1d|comment:Reverse DNA oligo is methylated on Adenine6.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.0x10^-6(molar)	2013/05/10	2014/10/16	-	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:A6366D0AED79E3C6	false	binding-associated region:1-12	-	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-6671633	intact:EBI-6675502	-	-	psi-mi:hemimeth_dna_forw(display_short)|psi-mi:EBI-6671633(display_long)	psi-mi:hemimeth_dna_rev(display_short)|psi-mi:EBI-6675502(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Guarné et al. (2002)	pubmed:12379844|imex:IM-20594	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671646|imex:IM-20594-4|wwpdb:1lrr	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	pubmed:12379844(primary-reference)	pubmed:12379844(primary-reference)	-	-	-	figure legend:Fig. 2|3d-r-factors:Rwork = 0.25; Rfree = 0.28|3d-resolution:2.65 A|comment:Reverse DNA oligo is methylated on Adenine6.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	-	-	intact-crc:07E35A688675EECB	false	binding-associated region:1-12	binding-associated region:1-14	1	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-6671633	uniprotkb:P0AFY8	-	intact:EBI-552553|uniprotkb:P36658|ensemblbacteria:AAC73781|ensemblbacteria:BAA35336	psi-mi:hemimeth_dna_forw(display_short)|psi-mi:EBI-6671633(display_long)	psi-mi:seqa_ecoli(display_long)|uniprotkb:seqA(gene name)|psi-mi:seqA(display_short)|uniprotkb:b0687(locus name)|uniprotkb:JW0674(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Guarné et al. (2002)	pubmed:12379844|imex:IM-20594	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6671646|imex:IM-20594-4|wwpdb:1lrr	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	pubmed:12379844(primary-reference)	refseq:NP_415213.1|refseq:WP_000848387.1|dip:DIP-48017N|ensemblbacteria:AAC73781(transcript)|ensemblbacteria:b0687(gene)|ensemblbacteria:BAA35336(gene)|ensemblbacteria:BAA35336(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044729"(hemi-methylated DNA-binding)|go:"GO:0090143"(nucleoid organization)|go:"GO:1990097"(SeqA-DNA complex)|interpro:IPR005621(Regulation modulator SeqA)|interpro:IPR010985(Ribbon-helix-helix)|interpro:IPR013321(Arc-type ribbon-helix-helix)|interpro:IPR026577|interpro:IPR033761|interpro:IPR036835|rcsb pdb:1IU3|rcsb pdb:1J3E|rcsb pdb:1LRR|rcsb pdb:1XRX|rcsb pdb:2CH3|rcsb pdb:3FMT	-	-	crc64:37D9078CA3D7229B	figure legend:Fig. 2|3d-r-factors:Rwork = 0.25; Rfree = 0.28|3d-resolution:2.65 A|comment:Reverse DNA oligo is methylated on Adenine6.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	-	rogid:ma8bSMqGLrkT6Tms0Ye4k+zQW/I83333	intact-crc:07E35A688675EECB	false	binding-associated region:1-12	sufficient binding region:51-181|L-selenomethionine:?-?	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)