#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q95MP1 uniprotkb:Q8MJ87 intact:EBI-6557379|ensembl:ENSBTAP00000010954 intact:EBI-6557364 psi-mi:aipl1_bovin(display_long)|uniprotkb:AIPL1(gene name)|psi-mi:AIPL1(display_short) psi-mi:nub1_bovin(display_long)|uniprotkb:NUB1(gene name)|psi-mi:NUB1(display_short)|uniprotkb:Negative regulator of ubiquitin-like proteins 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Akey et al. (2002) imex:IM-18712|pubmed:12374762 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6557362|imex:IM-18712-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSBTAG00000008318(gene)|ensembl:ENSBTAT00000010954(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001918"(farnesylated protein binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0018343"(protein farnesylation)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031209|interpro:IPR039663|refseq:NP_776659.1 go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR039749|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/03/11 2014/10/16 rogid:OGBh/YGKgkSnfVAhuFHbMjyy0/I9913 rogid:SYX8mhLd6rhwmc50Iw5CIkjB6qk9913 intact-crc:59CA55E57AD9CB84|rigid:h8KZZTeeFSOvy8m38D/u9BCbHs8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MJ87 uniprotkb:Q95MP1 intact:EBI-6557364 intact:EBI-6557379|ensembl:ENSBTAP00000010954 psi-mi:nub1_bovin(display_long)|uniprotkb:NUB1(gene name)|psi-mi:NUB1(display_short)|uniprotkb:Negative regulator of ubiquitin-like proteins 1(gene name synonym) psi-mi:aipl1_bovin(display_long)|uniprotkb:AIPL1(gene name)|psi-mi:AIPL1(display_short) psi-mi:"MI:0018"(two hybrid) Akey et al. (2002) imex:IM-18712|pubmed:12374762 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6557401|imex:IM-18712-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR039749|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote) ensembl:ENSBTAG00000008318(gene)|ensembl:ENSBTAT00000010954(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001918"(farnesylated protein binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0018343"(protein farnesylation)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031209|interpro:IPR039663|refseq:NP_776659.1 - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/03/11 2014/10/16 rogid:SYX8mhLd6rhwmc50Iw5CIkjB6qk9913 rogid:OGBh/YGKgkSnfVAhuFHbMjyy0/I9913 intact-crc:C07B6C6A3A693750|rigid:h8KZZTeeFSOvy8m38D/u9BCbHs8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NZN9 uniprotkb:Q9Y5A7 intact:EBI-6557414|ensembl:ENSP00000370521|uniprotkb:D3DTM4|uniprotkb:Q6ZZB6|uniprotkb:Q8N6A0|uniprotkb:Q9H873|uniprotkb:Q9NS10|uniprotkb:Q659W3|uniprotkb:Q659W4 intact:EBI-3936907|uniprotkb:Q75MR9|uniprotkb:Q9BXR2|uniprotkb:Q8IX22|uniprotkb:O95422|ensembl:ENSP00000418234|ensembl:ENSP00000454264 psi-mi:aipl1_human(display_long)|uniprotkb:AIPL1(gene name)|psi-mi:AIPL1(display_short)|uniprotkb:AIPL2(gene name synonym) psi-mi:nub1_human(display_long)|uniprotkb:NUB1(gene name)|psi-mi:NUB1(display_short)|uniprotkb:NYREN18(gene name synonym)|uniprotkb:Negative regulator of ubiquitin-like proteins 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Akey et al. (2002) imex:IM-18712|pubmed:12374762 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6557450|imex:IM-18712-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272329.1|refseq:NP_001272330.1|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0018343"(protein farnesylation)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031209|interpro:IPR039663|rcsb pdb:5U9A|rcsb pdb:5U9I|rcsb pdb:5U9J|rcsb pdb:5U9K|rcsb pdb:5V35|rcsb pdb:6PX0|ensembl:ENSG00000129221(gene)|ensembl:ENST00000381129(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001918"(farnesylated protein binding)|refseq:NP_001272328.1|refseq:NP_001272332.1|refseq:NP_001028226.1|refseq:NP_001028227.1|refseq:NP_055151.3 ensembl:ENSG00000013374(gene)|ensembl:ENST00000470229(transcript)|ensembl:ENST00000568733(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR009060(UBA-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR039749|interpro:IPR041207|rcsb pdb:1WJU|reactome:R-HSA-8951664|refseq:NP_001230280.1|refseq:NP_057202.3|refseq:XP_005250068.1|refseq:XP_016867795.1 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/03/11 2014/10/16 rogid:yOBFTxGRiIgyInsIxwLKrBMy+VI9606 rogid:RO3+wwxnIE0O0kfXxL8Jnn5bgxY9606 intact-crc:EB88CCBE004960FB|rigid:gkZNn98jNdFUIG66k7P/Jlff6ao false sufficient binding region:116-207|sufficient binding region:1-117|mutation decreasing interaction:53-53|mutation decreasing interaction:262-262|mutation decreasing interaction:79-79|mutation decreasing interaction:96-96|sufficient binding region:298-384|mutation decreasing interaction:302-302|necessary binding region:278-384 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-6678057 uniprotkb:Q9NZN9 - intact:EBI-6557414|ensembl:ENSP00000370521|uniprotkb:D3DTM4|uniprotkb:Q6ZZB6|uniprotkb:Q8N6A0|uniprotkb:Q9H873|uniprotkb:Q9NS10|uniprotkb:Q659W3|uniprotkb:Q659W4 psi-mi:nub1_chlae_protein(display_short)|psi-mi:EBI-6678057(display_long) psi-mi:aipl1_human(display_long)|uniprotkb:AIPL1(gene name)|psi-mi:AIPL1(display_short)|uniprotkb:AIPL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Akey et al. (2002) imex:IM-18712|pubmed:12374762 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6557484|imex:IM-18712-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001272329.1|refseq:NP_001272330.1|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0018343"(protein farnesylation)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031209|interpro:IPR039663|rcsb pdb:5U9A|rcsb pdb:5U9I|rcsb pdb:5U9J|rcsb pdb:5U9K|rcsb pdb:5V35|rcsb pdb:6PX0|ensembl:ENSG00000129221(gene)|ensembl:ENST00000381129(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001918"(farnesylated protein binding)|refseq:NP_001272328.1|refseq:NP_001272332.1|refseq:NP_001028226.1|refseq:NP_001028227.1|refseq:NP_055151.3 - comment:Similar to human NUB1 UniProt Ac Q9Y5A7 - figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_6)|taxid:9534(African green monkey kidney cell line) - 2013/03/11 2014/10/16 - rogid:yOBFTxGRiIgyInsIxwLKrBMy+VI9606 intact-crc:5221EFB1F6232C16 false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y5A7 uniprotkb:Q9NZN9 intact:EBI-3936907|uniprotkb:Q75MR9|uniprotkb:Q9BXR2|uniprotkb:Q8IX22|uniprotkb:O95422|ensembl:ENSP00000418234|ensembl:ENSP00000454264 intact:EBI-6557414|ensembl:ENSP00000370521|uniprotkb:D3DTM4|uniprotkb:Q6ZZB6|uniprotkb:Q8N6A0|uniprotkb:Q9H873|uniprotkb:Q9NS10|uniprotkb:Q659W3|uniprotkb:Q659W4 psi-mi:nub1_human(display_long)|uniprotkb:NUB1(gene name)|psi-mi:NUB1(display_short)|uniprotkb:NYREN18(gene name synonym)|uniprotkb:Negative regulator of ubiquitin-like proteins 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-18(gene name synonym) psi-mi:aipl1_human(display_long)|uniprotkb:AIPL1(gene name)|psi-mi:AIPL1(display_short)|uniprotkb:AIPL2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Akey et al. (2002) imex:IM-18712|pubmed:12374762 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6557496|imex:IM-18712-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000013374(gene)|ensembl:ENST00000470229(transcript)|ensembl:ENST00000568733(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR009060(UBA-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR039749|interpro:IPR041207|rcsb pdb:1WJU|reactome:R-HSA-8951664|refseq:NP_001230280.1|refseq:NP_057202.3|refseq:XP_005250068.1|refseq:XP_016867795.1 refseq:NP_001272329.1|refseq:NP_001272330.1|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0018343"(protein farnesylation)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031209|interpro:IPR039663|rcsb pdb:5U9A|rcsb pdb:5U9I|rcsb pdb:5U9J|rcsb pdb:5U9K|rcsb pdb:5V35|rcsb pdb:6PX0|ensembl:ENSG00000129221(gene)|ensembl:ENST00000381129(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001918"(farnesylated protein binding)|refseq:NP_001272328.1|refseq:NP_001272332.1|refseq:NP_001028226.1|refseq:NP_001028227.1|refseq:NP_055151.3 - - - figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-y7)|taxid:9606(Homo sapiens Y7 retinoblastoma cells) - 2013/03/11 2014/10/16 rogid:RO3+wwxnIE0O0kfXxL8Jnn5bgxY9606 rogid:yOBFTxGRiIgyInsIxwLKrBMy+VI9606 intact-crc:A5D174B72FE93B2F|rigid:gkZNn98jNdFUIG66k7P/Jlff6ao false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)