#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P42768	uniprotkb:P08103	intact:EBI-346375|uniprotkb:Q9BU11|uniprotkb:Q9UNJ9|ensembl:ENSP00000365891	intact:EBI-6248894|uniprotkb:Q0VH03|uniprotkb:Q3UD17	psi-mi:wasp_human(display_long)|uniprotkb:WAS(gene name)|psi-mi:WAS(display_short)|uniprotkb:IMD2(gene name synonym)	psi-mi:hck_mouse(display_long)|uniprotkb:Hck(gene name)|psi-mi:Hck(display_short)|uniprotkb:B-cell/myeloid kinase(gene name synonym)|uniprotkb:Hematopoietic cell kinase(gene name synonym)|uniprotkb:Hemopoietic cell kinase(gene name synonym)|uniprotkb:p56-HCK/p59-HCK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cory et al. (2002)	imex:IM-18848|pubmed:12235133	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6478128|imex:IM-18848-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000368.1|dip:DIP-431N|ensembl:ENSG00000015285(gene)|ensembl:ENST00000376701(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0007596"(blood coagulation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008544"(epidermis development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P42768|rcsb pdb:1CEE|rcsb pdb:1EJ5|rcsb pdb:1T84|rcsb pdb:2A3Z|rcsb pdb:2K42|rcsb pdb:2OT0|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422	go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|reactome:R-MMU-2029481|reactome:R-MMU-912631|reactome:R-MMU-9674555|reactome:R-MMU-9705462|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005901"(caveola)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006887"(exocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030133"(transport vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|mint:P08103|refseq:NP_001165588.1|refseq:NP_034537.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035851|interpro:IPR036028|interpro:IPR036860	-	-	-	figure legend:Fig 1C.|comment:"The interaction between WASp and Hck was unaffected in the presence of the kinase dead mutant of Hck (267 Hck). The interaction was also unaffected by the presence or absence of active (V12) or dominant negative (N17) CDC42."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/01/14	2014/10/16	rogid:VHtlRNZQYpIU2btQV28coDiNsO09606	rogid:ZkVHYxfS6PGWqyvA53/MKE5mv5A10090	intact-crc:522B9B50F60AD8A5|rigid:TrmpQpfm8Ma+W50VZly2fCCKyEM	false	vsv tag:c-c	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P08103	uniprotkb:P42768	intact:EBI-6248894|uniprotkb:Q0VH03|uniprotkb:Q3UD17	intact:EBI-346375|uniprotkb:Q9BU11|uniprotkb:Q9UNJ9|ensembl:ENSP00000365891	psi-mi:hck_mouse(display_long)|uniprotkb:Hck(gene name)|psi-mi:Hck(display_short)|uniprotkb:B-cell/myeloid kinase(gene name synonym)|uniprotkb:Hematopoietic cell kinase(gene name synonym)|uniprotkb:Hemopoietic cell kinase(gene name synonym)|uniprotkb:p56-HCK/p59-HCK(gene name synonym)	psi-mi:wasp_human(display_long)|uniprotkb:WAS(gene name)|psi-mi:WAS(display_short)|uniprotkb:IMD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cory et al. (2002)	imex:IM-18848|pubmed:12235133	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6478146|imex:IM-18848-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|reactome:R-MMU-2029481|reactome:R-MMU-912631|reactome:R-MMU-9674555|reactome:R-MMU-9705462|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005901"(caveola)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006887"(exocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030133"(transport vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|mint:P08103|refseq:NP_001165588.1|refseq:NP_034537.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035851|interpro:IPR036028|interpro:IPR036860	refseq:NP_000368.1|dip:DIP-431N|ensembl:ENSG00000015285(gene)|ensembl:ENST00000376701(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0007596"(blood coagulation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008544"(epidermis development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P42768|rcsb pdb:1CEE|rcsb pdb:1EJ5|rcsb pdb:1T84|rcsb pdb:2A3Z|rcsb pdb:2K42|rcsb pdb:2OT0|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422	-	-	-	figure legend:Fig 2A.|comment:"Phospho forms of Hck were not detected by the anti-phosphotyrosine antibodies when the kinase dead mutant Hck (267 Hck) were coimmunoprecipitated with WASp, showing an absence of phosphorylation by the kinase dead mutant (Fig 1B). Phospo forms of Hck were not detected when Hck was coimmunoprecipitated with WASp in the presence of phosphatases such as CIP, PP1 and LAR (Fig 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/01/14	2014/10/16	rogid:ZkVHYxfS6PGWqyvA53/MKE5mv5A10090	rogid:VHtlRNZQYpIU2btQV28coDiNsO09606	intact-crc:0920CF8B1FED5A36|rigid:TrmpQpfm8Ma+W50VZly2fCCKyEM	false	flag tag:n-n	vsv tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P42768	uniprotkb:P08103	intact:EBI-346375|uniprotkb:Q9BU11|uniprotkb:Q9UNJ9|ensembl:ENSP00000365891	intact:EBI-6248894|uniprotkb:Q0VH03|uniprotkb:Q3UD17	psi-mi:wasp_human(display_long)|uniprotkb:WAS(gene name)|psi-mi:WAS(display_short)|uniprotkb:IMD2(gene name synonym)	psi-mi:hck_mouse(display_long)|uniprotkb:Hck(gene name)|psi-mi:Hck(display_short)|uniprotkb:B-cell/myeloid kinase(gene name synonym)|uniprotkb:Hematopoietic cell kinase(gene name synonym)|uniprotkb:Hemopoietic cell kinase(gene name synonym)|uniprotkb:p56-HCK/p59-HCK(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Cory et al. (2002)	imex:IM-18848|pubmed:12235133	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6478166|imex:IM-18848-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000368.1|dip:DIP-431N|ensembl:ENSG00000015285(gene)|ensembl:ENST00000376701(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0007596"(blood coagulation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008544"(epidermis development)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P42768|rcsb pdb:1CEE|rcsb pdb:1EJ5|rcsb pdb:1T84|rcsb pdb:2A3Z|rcsb pdb:2K42|rcsb pdb:2OT0|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422	go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|reactome:R-MMU-2029481|reactome:R-MMU-912631|reactome:R-MMU-9674555|reactome:R-MMU-9705462|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005901"(caveola)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006887"(exocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030133"(transport vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|mint:P08103|refseq:NP_001165588.1|refseq:NP_034537.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035851|interpro:IPR036028|interpro:IPR036860	go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/01/14	2014/10/16	rogid:VHtlRNZQYpIU2btQV28coDiNsO09606	rogid:ZkVHYxfS6PGWqyvA53/MKE5mv5A10090	intact-crc:39F41F2D262190D5|rigid:TrmpQpfm8Ma+W50VZly2fCCKyEM	false	glutathione s tranferase tag:?-?|sufficient binding region:201-321	flag tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P08103	-	intact:EBI-6248894|uniprotkb:Q0VH03|uniprotkb:Q3UD17	-	psi-mi:hck_mouse(display_long)|uniprotkb:Hck(gene name)|psi-mi:Hck(display_short)|uniprotkb:B-cell/myeloid kinase(gene name synonym)|uniprotkb:Hematopoietic cell kinase(gene name synonym)|uniprotkb:Hemopoietic cell kinase(gene name synonym)|uniprotkb:p56-HCK/p59-HCK(gene name synonym)	-	psi-mi:"MI:0424"(protein kinase assay)	Cory et al. (2002)	imex:IM-18848|pubmed:12235133	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-6478176|imex:IM-18848-4	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|reactome:R-MMU-2029481|reactome:R-MMU-912631|reactome:R-MMU-9674555|reactome:R-MMU-9705462|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005901"(caveola)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006887"(exocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030133"(transport vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|mint:P08103|refseq:NP_001165588.1|refseq:NP_034537.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR035851|interpro:IPR036028|interpro:IPR036860	-	go:"GO:0004672"(protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)	-	-	figure legend:Fig 3B.|comment:"Interaction type: Autophosphorylation of Hck."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/01/14	2014/10/16	rogid:ZkVHYxfS6PGWqyvA53/MKE5mv5A10090	-	intact-crc:171EC5DB6123C6B1	false	flag tag:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	-