#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99996 uniprotkb:P51787 intact:EBI-1048311|uniprotkb:O14869|uniprotkb:O43355|uniprotkb:O94895|uniprotkb:Q75N20|uniprotkb:Q9UQH3|uniprotkb:Q9UQQ4|uniprotkb:Q9Y6B8|uniprotkb:A4D1F0|uniprotkb:Q9Y6Y2|uniprotkb:A4D1F2|uniprotkb:A4D1F4|ensembl:ENSP00000348573 intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840 psi-mi:akap9_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:KIAA0803(gene name synonym) psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Marx et al. (2002) pubmed:11799244|imex:IM-26706 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8802725|imex:IM-26706-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005742.4|refseq:NP_671714.1|ensembl:ENSG00000127914(gene)|ensembl:ENST00000356239(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR005539(ELK)|interpro:IPR019528|interpro:IPR028745|mint:Q99996|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5576890|reactome:R-HSA-5576893|reactome:R-HSA-5620912|reactome:R-HSA-6802952|reactome:R-HSA-8854518|ensembl:ENSP00000348573|ensembl:ENST00000680766|ensembl:ENSP00000505204|dip:DIP-29942N refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N - - caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21 figure legend:Fig 1D and results text|comment:In Figure 1D anti-PKA, and anti-PP1 not specific enough to annotate bound protein.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/18 2018/04/30 rogid:LQUNbTHUgEsjayFEZvczC4e90Nw9606 rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606 intact-crc:ACDD80CE9526474C|rigid:d+XXgcwXjAevOBWLw7bZ2xQLB/w false - sufficient binding region:526-676|mutation decreasing interaction:602-602,609-609 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51787 uniprotkb:Q70FJ1 intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840 intact:EBI-645887|uniprotkb:Q3TH74|uniprotkb:Q80TR6 psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym) psi-mi:akap9_mouse(display_long)|uniprotkb:Akap9(gene name)|psi-mi:Akap9(display_short)|uniprotkb:Kiaa0803(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Marx et al. (2002) pubmed:11799244|imex:IM-26706 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8802739|imex:IM-26706-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N refseq:NP_919444.2|interpro:IPR019528|interpro:IPR028745|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097729"(9+2 motile cilium)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0120219"(subapical part of cell)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5576890|reactome:R-MMU-5576893|reactome:R-MMU-5620912|reactome:R-MMU-8854518|mint:Q70FJ1 - caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21 - figure legend:Fig 1D and results text, 2C|comment:In Figure 1D anti-PKA, and anti-PP1 not specific enough to annotate bound protein. In Figure 2C anti-PKA, and anti-PP1 not specific enough to annotate bound protein.|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/18 2014/10/16 rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606 rogid:9yyCeoX35wNULJg413iGM9TIQxA10090 intact-crc:C2D49BE07486000A|rigid:mQPXmM56kHr/iNig9r8953mXDJo false sufficient binding region:526-676|mutation decreasing interaction:602-602,609-609 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51787 uniprotkb:Q70FJ1 intact:EBI-359667|intact:EBI-1760548|uniprotkb:O00347|uniprotkb:O60607|uniprotkb:O94787|uniprotkb:Q7Z6G9|uniprotkb:Q92960|uniprotkb:Q9UMN8|uniprotkb:Q9UMN9|uniprotkb:Q14D14|intact:EBI-1965607|ensembl:ENSP00000155840 intact:EBI-645887|uniprotkb:Q3TH74|uniprotkb:Q80TR6 psi-mi:kcnq1_human(display_long)|uniprotkb:KCNQ1(gene name)|psi-mi:KCNQ1(display_short)|uniprotkb:KCNA8(gene name synonym)|uniprotkb:KCNA9(gene name synonym)|uniprotkb:KVLQT1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym) psi-mi:akap9_mouse(display_long)|uniprotkb:Akap9(gene name)|psi-mi:Akap9(display_short)|uniprotkb:Kiaa0803(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marx et al. (2002) pubmed:11799244|imex:IM-26706 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8802699|imex:IM-26706-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000209.2|refseq:NP_861463.1|ensembl:ENSG00000053918(gene)|ensembl:ENST00000155840(transcript)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|mint:P51787|rcsb pdb:3BJ4|rcsb pdb:3HFC|rcsb pdb:3HFE|rcsb pdb:4UMO|rcsb pdb:4V0C|rcsb pdb:6MIE|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|reactome:R-HSA-1296072|reactome:R-HSA-5576890|reactome:R-HSA-5576893|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|dip:DIP-27591N|dip:DIP-29941N refseq:NP_919444.2|interpro:IPR019528|interpro:IPR028745|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097729"(9+2 motile cilium)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0120219"(subapical part of cell)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5576890|reactome:R-MMU-5576893|reactome:R-MMU-5620912|reactome:R-MMU-8854518|mint:Q70FJ1 - caution:This sequence has been withdrawn from Uniprot.|crc64:ADFCA9E2B9763B21 - figure legend:Fig 1C, 2C|comment:"In Figure 1C anti-PKA (catalytic subunit), anti-RII (PKA regulatory subunit), anti-PP1 (catalytic subunit of PP1) not specific enough to annotate bound protein. In Figure 2C anti-PKA, and anti-PP1 not specific enough to annotate bound protein."|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2013/10/18 2019/02/01 rogid:w5Bp2fzyW56IIPAgVjXWgOOAlr49606 rogid:9yyCeoX35wNULJg413iGM9TIQxA10090 intact-crc:F2B93D4FD2F3DE82|rigid:mQPXmM56kHr/iNig9r8953mXDJo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)