#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27958-PRO_0000037573 uniprotkb:P27958-PRO_0000037573 intact:EBI-3649474|intact:EBI-6904428 intact:EBI-3649474|intact:EBI-6904428 psi-mi:p27958-pro_0000037573(display_long) psi-mi:p27958-pro_0000037573(display_long) psi-mi:"MI:0018"(two hybrid) Khu et al. (2001) pubmed:11119590|imex:IM-26021 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8872740|imex:IM-26021-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) intact:EBI-706378(chain-parent) - chain-seq-start:1027|chain-seq-end:1657 chain-seq-start:1027|chain-seq-end:1657 figure legend:Fig. 1A, 2A and 5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/11/23 2014/10/16 rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746 rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746 intact-crc:E72FD62C749BD676|rigid:Xtg1+g+kW6bwFSViwqUysFanyv0 false sufficient binding region:162-375|mutation decreasing interaction strength:288-288|mutation decreasing interaction strength:266-266|mutation disrupting interaction strength:268-268|mutation decreasing interaction strength:267-267|mutation disrupting interaction strength:269-269 sufficient binding region:162-335 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037573 uniprotkb:P27958-PRO_0000037573 intact:EBI-3649474|intact:EBI-6904428 intact:EBI-3649474|intact:EBI-6904428 psi-mi:p27958-pro_0000037573(display_long) psi-mi:p27958-pro_0000037573(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Khu et al. (2001) pubmed:11119590|imex:IM-26021 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8872758|imex:IM-26021-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) intact:EBI-706378(chain-parent) - chain-seq-start:1027|chain-seq-end:1657 chain-seq-start:1027|chain-seq-end:1657 figure legend:Fig. 1B and 2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast) - 2013/11/23 2014/10/16 rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746 rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746 intact-crc:62635FAB6AE4E8D5|rigid:Xtg1+g+kW6bwFSViwqUysFanyv0 false sufficient binding region:182-335|flag tag:?-? sufficient binding region:182-335|myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P27958-PRO_0000037573 intact:EBI-9029720 intact:EBI-3649474|intact:EBI-6904428 - psi-mi:p27958-pro_0000037573(display_long) psi-mi:olg39(display_short)|psi-mi:EBI-9029720(display_long) psi-mi:"MI:0071"(molecular sieving) Khu et al. (2001) pubmed:11119590|imex:IM-26021 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:11108(hcvh)|taxid:11108("Hepatitis C virus genotype 1a (isolate H) (HCV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8872780|imex:IM-26021-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0840"(stimulator) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0318"(nucleic acid) intact:EBI-706378(chain-parent) - - chain-seq-start:1027|chain-seq-end:1657 - figure legend:Fig. 3 and 4B|comment:"When 39-mer oligonucleotide (OLG39: 39ATAATGTGTGCTGCCTGCCACTCAACTGACTCAACT59) was added, NS3 formed a dimer."|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/23 2019/01/30 rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746 - intact-crc:FDE837466D3EED91 false sufficient binding region:182-631|mutation decreasing interaction:288-288|mutation decreasing interaction:266-266|mutation decreasing interaction:267-267 - 2 - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27958-PRO_0000037573 intact:EBI-9036743 intact:EBI-3649474|intact:EBI-6904428 - psi-mi:p27958-pro_0000037573(display_long) psi-mi:olg54_olg55(display_short)|psi-mi:EBI-9036743(display_long) psi-mi:"MI:0415"(enzymatic study) Khu et al. (2001) pubmed:11119590|imex:IM-26021 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0414"(enzymatic reaction) psi-mi:"MI:1335"(HPIDb) intact:EBI-8872821|imex:IM-26021-6 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) intact:EBI-706378(chain-parent) - go:"GO:0004386"(helicase activity) chain-seq-start:1027|chain-seq-end:1657 - figure legend:Fig. 6|comment:double-stranded oligodeoxynucleotide used as a substrate|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/23 2019/01/30 rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746 - intact-crc:DE2946DA63F081EA false mutation decreasing interaction rate:267-267|mutation decreasing interaction rate:288-288|sufficient binding region:182-631|mutation decreasing interaction rate:266-266 - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)