#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UPY8 uniprotkb:O95996 intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short) psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8842039|imex:IM-22158-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7 refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 - - - figure legend:Fig. 6a|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/11/01 2014/10/16 rogid:LHuufxyNrygS3iFW5mmg13R43NE9606 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 intact-crc:A71E6408E7112F53|rigid:LyKZ48/Pm7emxP/NtvkSrtTl6Qs false flag tag:n-n myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPY8 uniprotkb:O95996 intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short) psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8842052|imex:IM-22158-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7 refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 - - - figure legend:Fig. 6b|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/11/01 2014/10/16 rogid:LHuufxyNrygS3iFW5mmg13R43NE9606 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 intact-crc:A3885665E7284F07|rigid:LyKZ48/Pm7emxP/NtvkSrtTl6Qs false flag tag:n-n myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95996 uniprotkb:Q9UPY8 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121 psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short) psi-mi:"MI:0663"(confocal microscopy) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8850639|imex:IM-22158-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7 - - - figure legend:Fig. 7|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/11/01 2014/10/16 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 rogid:LHuufxyNrygS3iFW5mmg13R43NE9606 intact-crc:B2CE636E4F2DBFF6|rigid:LyKZ48/Pm7emxP/NtvkSrtTl6Qs false myc tag:c-c flag tag:n-n - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:O95996 uniprotkb:Q15691 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:"MI:0018"(two hybrid) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8840634|imex:IM-22158-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N - - - dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/11/01 2014/10/16 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 intact-crc:2BAE9A3FD32DADFD|rigid:UJaZOHx78Mq64qUDW7WT9bfhGjA false sufficient binding region:?-2303 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UPY8 uniprotkb:O95996 intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short) psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8840649|imex:IM-22158-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7 refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 - - - dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/11/01 2014/10/16 rogid:LHuufxyNrygS3iFW5mmg13R43NE9606 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 intact-crc:B66E3B5C357CDEA6|rigid:LyKZ48/Pm7emxP/NtvkSrtTl6Qs false - sufficient binding region:?-2303 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UPY8 uniprotkb:O95996 intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short) psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:"MI:0096"(pull down) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8840717|imex:IM-22158-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7 refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 - - - figure legend:Fig. 5b|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/01 2014/10/16 rogid:LHuufxyNrygS3iFW5mmg13R43NE9606 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 intact-crc:B3857D9FD5CCA465|rigid:LyKZ48/Pm7emxP/NtvkSrtTl6Qs false 35s radiolabel:?-? glutathione s tranferase tag:n-n|sufficient binding region:2071-2121 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q15691 uniprotkb:O95996 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:"MI:0096"(pull down) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8840719|imex:IM-22158-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 - - - figure legend:Fig. 5b|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/01 2014/10/16 rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 intact-crc:350A9DEFEF8274E8|rigid:UJaZOHx78Mq64qUDW7WT9bfhGjA false 35s radiolabel:?-? glutathione s tranferase tag:n-n|sufficient binding region:2071-2121 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9UPY8 uniprotkb:O95996 intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short) psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:"MI:0096"(pull down) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8840687|imex:IM-22158-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7 refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 - - - figure legend:Fig. 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/01 2014/10/16 rogid:LHuufxyNrygS3iFW5mmg13R43NE9606 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 intact-crc:50DCCF3193C04CC3|rigid:LyKZ48/Pm7emxP/NtvkSrtTl6Qs false glutathione s tranferase tag:n-n 35s radiolabel:?-?|sufficient binding region:1372-2303 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O95996 uniprotkb:Q15691 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:"MI:0096"(pull down) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8840681|imex:IM-22158-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N - - - figure legend:Fig. 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/01 2014/10/16 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 intact-crc:D961C03932459A50|rigid:UJaZOHx78Mq64qUDW7WT9bfhGjA false sufficient binding region:1372-2303|35s radiolabel:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O95996 uniprotkb:Q9UPY8 intact:EBI-1053045|uniprotkb:Q05BW4|uniprotkb:Q9UBZ1|uniprotkb:Q9UEM8|uniprotkb:Q9UQJ8|uniprotkb:Q9UQJ9|uniprotkb:Q9Y632|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073 intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121 psi-mi:apcl_human(display_long)|uniprotkb:Adenomatous polyposis coli protein-like(gene name synonym)|uniprotkb:APC2(gene name)|psi-mi:APC2(display_short)|uniprotkb:APCL(gene name synonym) psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short) psi-mi:"MI:0663"(confocal microscopy) Nakagawa et al. (2000) pubmed:10644998|imex:IM-22158 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1332"(bhf-ucl) intact:EBI-8850616|imex:IM-22158-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005874.1|ensembl:ENSP00000233607|ensembl:ENSP00000442954|ensembl:ENSP00000467073|ensembl:ENSG00000115266(gene)|ensembl:ENST00000233607(transcript)|ensembl:ENST00000535453(transcript)|ensembl:ENST00000590469(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001708"(cell fate specification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000225(Armadillo)|interpro:IPR009223(APC cysteine-rich)|interpro:IPR009224(SAMP)|interpro:IPR009234(APC basic)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818|interpro:IPR026831|interpro:IPR026837|interpro:IPR032038|interpro:IPR036149|interpro:IPR041257|mint:O95996|refseq:XP_006722672.1 refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7 - - - figure legend:Fig. 7|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line) - 2013/11/01 2014/10/16 rogid:v1BSNAoDD3R0+lrhI5zsOZvxFjQ9606 rogid:LHuufxyNrygS3iFW5mmg13R43NE9606 intact-crc:6995A3D454D03424|rigid:LyKZ48/Pm7emxP/NtvkSrtTl6Qs false myc tag:c-c flag tag:n-n - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry)