#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07953	uniprotkb:P07953	intact:EBI-709873|ensembl:ENSRNOP00000035212|uniprotkb:P16119	intact:EBI-709873|ensembl:ENSRNOP00000035212|uniprotkb:P16119	psi-mi:f261_rat(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase liver isozyme(gene name synonym)|uniprotkb:Pfkfb1(gene name)|psi-mi:Pfkfb1(display_short)	psi-mi:f261_rat(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase liver isozyme(gene name synonym)|uniprotkb:Pfkfb1(gene name)|psi-mi:Pfkfb1(display_short)	psi-mi:"MI:0018"(two hybrid)	Langer et al. (2012)	pubmed:22668829|mint:MINT-8361543	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7905380|mint:MINT-8361548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003094(Fructose-2,6-bisphosphatase)|rgd:3307|refseq:NP_036753.4|ensembl:ENSRNOT00000033656(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|ensembl:ENSRNOG00000000165(gene)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033762"(response to glucagon)|go:"GO:0042594"(response to starvation)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043540"(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:1C7Z|rcsb pdb:1C80|rcsb pdb:1C81|rcsb pdb:1FBT|rcsb pdb:1TIP|reactome:R-RNO-9634600|mint:MINT-8361551(identity)	interpro:IPR003094(Fructose-2,6-bisphosphatase)|rgd:3307|refseq:NP_036753.4|ensembl:ENSRNOT00000033656(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|ensembl:ENSRNOG00000000165(gene)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033762"(response to glucagon)|go:"GO:0042594"(response to starvation)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043540"(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:1C7Z|rcsb pdb:1C80|rcsb pdb:1C81|rcsb pdb:1FBT|rcsb pdb:1TIP|reactome:R-RNO-9634600|mint:MINT-8361550(identity)	-	-	-	figure legend:f2|comment:homomint|comment:mint	taxid:9534(chlae-cos)|taxid:9534(Chlorocebus aethiops)	-	2012/04/02	2014/10/16	rogid:rL9vZlrhsbopiNmyJQxtiv/la4E10116	rogid:rL9vZlrhsbopiNmyJQxtiv/la4E10116	intact-crc:D234CFC8F1DEC97A|rigid:yvnKfoIwTnmMTmxg5YdRcbQrrmU	false	fusion protein:?-?(MINT-8361564)|mutation increasing interaction:33-33(MINT-8361567)|mutation increasing interaction:259-259(MINT-8361569)	fusion protein:?-?(MINT-8361553)|mutation increasing interaction:33-33(MINT-8361557)|mutation increasing interaction:259-259(MINT-8361560)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07953	uniprotkb:P07953	intact:EBI-709873|ensembl:ENSRNOP00000035212|uniprotkb:P16119	intact:EBI-709873|ensembl:ENSRNOP00000035212|uniprotkb:P16119	psi-mi:f261_rat(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase liver isozyme(gene name synonym)|uniprotkb:Pfkfb1(gene name)|psi-mi:Pfkfb1(display_short)	psi-mi:f261_rat(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase liver isozyme(gene name synonym)|uniprotkb:Pfkfb1(gene name)|psi-mi:Pfkfb1(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Langer et al. (2012)	pubmed:22668829|mint:MINT-8361543	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0471"(MINT)	intact:EBI-7905457|mint:MINT-8361572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003094(Fructose-2,6-bisphosphatase)|rgd:3307|refseq:NP_036753.4|ensembl:ENSRNOT00000033656(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|ensembl:ENSRNOG00000000165(gene)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033762"(response to glucagon)|go:"GO:0042594"(response to starvation)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043540"(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:1C7Z|rcsb pdb:1C80|rcsb pdb:1C81|rcsb pdb:1FBT|rcsb pdb:1TIP|reactome:R-RNO-9634600|mint:MINT-8361582(identity)	interpro:IPR003094(Fructose-2,6-bisphosphatase)|rgd:3307|refseq:NP_036753.4|ensembl:ENSRNOT00000033656(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|ensembl:ENSRNOG00000000165(gene)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033762"(response to glucagon)|go:"GO:0042594"(response to starvation)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043540"(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:1C7Z|rcsb pdb:1C80|rcsb pdb:1C81|rcsb pdb:1FBT|rcsb pdb:1TIP|reactome:R-RNO-9634600|mint:MINT-8361574(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f4a f4b f4c	taxid:9534(chlae-cos)|taxid:9534(Chlorocebus aethiops)	-	2012/04/02	2014/10/16	rogid:rL9vZlrhsbopiNmyJQxtiv/la4E10116	rogid:rL9vZlrhsbopiNmyJQxtiv/la4E10116	intact-crc:95614D73DFA72A76|rigid:yvnKfoIwTnmMTmxg5YdRcbQrrmU	false	fusion protein:?-?(MINT-8361587)	fusion protein:?-?(MINT-8361579)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07953	uniprotkb:P07953	intact:EBI-709873|ensembl:ENSRNOP00000035212|uniprotkb:P16119	intact:EBI-709873|ensembl:ENSRNOP00000035212|uniprotkb:P16119	psi-mi:f261_rat(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase liver isozyme(gene name synonym)|uniprotkb:Pfkfb1(gene name)|psi-mi:Pfkfb1(display_short)	psi-mi:f261_rat(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase liver isozyme(gene name synonym)|uniprotkb:Pfkfb1(gene name)|psi-mi:Pfkfb1(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Langer et al. (2012)	pubmed:22668829|mint:MINT-8361543	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7905512|mint:MINT-8361598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003094(Fructose-2,6-bisphosphatase)|rgd:3307|refseq:NP_036753.4|ensembl:ENSRNOT00000033656(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|ensembl:ENSRNOG00000000165(gene)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033762"(response to glucagon)|go:"GO:0042594"(response to starvation)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043540"(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:1C7Z|rcsb pdb:1C80|rcsb pdb:1C81|rcsb pdb:1FBT|rcsb pdb:1TIP|reactome:R-RNO-9634600|mint:MINT-8361600(identity)	interpro:IPR003094(Fructose-2,6-bisphosphatase)|rgd:3307|refseq:NP_036753.4|ensembl:ENSRNOT00000033656(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|ensembl:ENSRNOG00000000165(gene)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033762"(response to glucagon)|go:"GO:0042594"(response to starvation)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043540"(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|rcsb pdb:1C7Z|rcsb pdb:1C80|rcsb pdb:1C81|rcsb pdb:1FBT|rcsb pdb:1TIP|reactome:R-RNO-9634600|mint:MINT-8361604(identity)	-	-	-	figure legend:f5|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/02	2014/10/16	rogid:rL9vZlrhsbopiNmyJQxtiv/la4E10116	rogid:rL9vZlrhsbopiNmyJQxtiv/la4E10116	intact-crc:095426ECB44A147D|rigid:yvnKfoIwTnmMTmxg5YdRcbQrrmU	false	fusion protein:?-?(MINT-8361601)	fusion protein:?-?(MINT-8361605)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)