#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:B2BUF1	uniprotkb:Q9UL18	intact:EBI-4291940	intact:EBI-527363|uniprotkb:Q5TA57|uniprotkb:Q6P4S0|ensembl:ENSP00000362300|ensembl:ENSP00000501450	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:ago1_human(display_long)|uniprotkb:AGO1(gene name)|psi-mi:AGO1(display_short)|uniprotkb:Argonaute RISC catalytic component 1(gene name synonym)|uniprotkb:EIF2C1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 1(gene name synonym)|uniprotkb:Putative RNA-binding protein Q99(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	dip:DIP-29193N|refseq:NP_036331.1|ensembl:ENSG00000092847(gene)|ensembl:ENST00000373204(transcript)|ensembl:ENST00000674304(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016442"(RISC complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UL18|rcsb pdb:1SI2|rcsb pdb:1SI3|rcsb pdb:4KRE|rcsb pdb:4KRF|rcsb pdb:4KXT|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|refseq:NP_001304051.1|refseq:NP_001304052.1	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:l/WmIsnfJjifEOoxOyG9zDo2ljQ9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:P27694	intact:EBI-4291940	intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:O14646	intact:EBI-4291940	intact:EBI-1560858|uniprotkb:Q17RZ3|ensembl:ENSP00000284049|ensembl:ENSP00000483667	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:chd1_human(display_long)|uniprotkb:ATP-dependent helicase CHD1(gene name synonym)|uniprotkb:CHD1(gene name)|psi-mi:CHD1(display_short)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_001261.2|refseq:XP_005271924.1|dip:DIP-38922N|ensembl:ENSG00000153922(gene)|ensembl:ENST00000284049(transcript)|ensembl:ENST00000614616(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14646|rcsb pdb:2B2T|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2B2Y|rcsb pdb:2N39|rcsb pdb:4B4C|rcsb pdb:4NW2|rcsb pdb:4O42|rcsb pdb:5AFW|reactome:R-HSA-9018519	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:KzH9c8MyoQh0Ph+KwSUktSa5qWM9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:O94906	intact:EBI-4291940	intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:Q6P1J9	intact:EBI-4291940	intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:P43243	intact:EBI-4291940	intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:Q9NZC9	intact:EBI-4291940	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:P09874	intact:EBI-4291940	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:P20042	intact:EBI-4291940	intact:EBI-711977|ensembl:ENSP00000364119|uniprotkb:Q9BVU0|uniprotkb:Q9UJE4	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:if2b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym)|uniprotkb:EIF2S2(gene name)|psi-mi:EIF2S2(display_short)|uniprotkb:EIF2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	ensembl:ENSG00000125977(gene)|ensembl:ENST00000374980(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002176"(male germ cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008584"(male gonad development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P20042|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_003899.2	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:64ZkCKZ5jRT6MEm9RK4AynY2ga49606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:O00567	intact:EBI-4291940	intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:O15371	intact:EBI-4291940	intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:Q9BV38	intact:EBI-4291940	intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:Q9Y3I0	intact:EBI-4291940	intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:O75821	intact:EBI-4291940	intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110503	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental  Fig2|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606	intact-crc:47345635E096F5D0|rigid:xvL3lwM14MJcAa4i3mimUevCMJ0	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:B2BUF1	uniprotkb:Q6P1J9	intact:EBI-4291940	intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110545	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654	go:"GO:0005634"(nucleus)	-	-	figure legend:1c|comment:293 cell nuclear extract has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606	intact-crc:F8AACA4B1E0BB33F|rigid:gB5lztrItG7V8Ub0JqmyslgCXi8	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q8N7H5	intact:EBI-4291940	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110545	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N	go:"GO:0005634"(nucleus)	-	-	figure legend:1c|comment:293 cell nuclear extract has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	intact-crc:F8AACA4B1E0BB33F|rigid:gB5lztrItG7V8Ub0JqmyslgCXi8	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q9NZC9	intact:EBI-4291940	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110545	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	go:"GO:0005634"(nucleus)	-	-	figure legend:1c|comment:293 cell nuclear extract has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:F8AACA4B1E0BB33F|rigid:gB5lztrItG7V8Ub0JqmyslgCXi8	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:O14646	intact:EBI-4291940	intact:EBI-1560858|uniprotkb:Q17RZ3|ensembl:ENSP00000284049|ensembl:ENSP00000483667	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:chd1_human(display_long)|uniprotkb:ATP-dependent helicase CHD1(gene name synonym)|uniprotkb:CHD1(gene name)|psi-mi:CHD1(display_short)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110545	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_001261.2|refseq:XP_005271924.1|dip:DIP-38922N|ensembl:ENSG00000153922(gene)|ensembl:ENST00000284049(transcript)|ensembl:ENST00000614616(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14646|rcsb pdb:2B2T|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2B2Y|rcsb pdb:2N39|rcsb pdb:4B4C|rcsb pdb:4NW2|rcsb pdb:4O42|rcsb pdb:5AFW|reactome:R-HSA-9018519	go:"GO:0005634"(nucleus)	-	-	figure legend:1c|comment:293 cell nuclear extract has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:KzH9c8MyoQh0Ph+KwSUktSa5qWM9606	intact-crc:F8AACA4B1E0BB33F|rigid:gB5lztrItG7V8Ub0JqmyslgCXi8	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N7H5	uniprotkb:B2BUF1	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	intact:EBI-4291940	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110604	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	-	-	-	figure legend:1e|comment:Purified PAF1 has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	intact-crc:1A0A8E159BA92DFC|rigid:14hHNgDa8z7h/fnNZQIzerhyzW8	false	-	sufficient binding region:220..220-230..230	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q6PD62	intact:EBI-4291940	intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110618	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N	-	-	-	figure legend:supplemental 3a|comment:Recombinant hPAF1C complex has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606	intact-crc:9DBB9544B219C4C5|rigid:aLkqXA0Q9dgc2/PeDDxA7Xs+8mg	false	sufficient binding region:220..220-230..230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q6P1J9	intact:EBI-4291940	intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110618	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654	-	-	-	figure legend:supplemental 3a|comment:Recombinant hPAF1C complex has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606	intact-crc:9DBB9544B219C4C5|rigid:aLkqXA0Q9dgc2/PeDDxA7Xs+8mg	false	sufficient binding region:220..220-230..230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q92541	intact:EBI-4291940	intact:EBI-1055239|uniprotkb:Q96BX6|ensembl:ENSP00000374280	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:rtf1_human(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:KIAA0252(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110618	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_055953.3|ensembl:ENSG00000137815(gene)|ensembl:ENST00000389629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR004343(Plus-3)|interpro:IPR036128|mint:Q92541|rcsb pdb:2BZE|rcsb pdb:2DB9|rcsb pdb:3U1U|rcsb pdb:4L1P|rcsb pdb:4L1U|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654	-	-	-	figure legend:supplemental 3a|comment:Recombinant hPAF1C complex has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:uWqJdVWJE0snWuZCdF0OkVWXRuI9606	intact-crc:9DBB9544B219C4C5|rigid:aLkqXA0Q9dgc2/PeDDxA7Xs+8mg	false	sufficient binding region:220..220-230..230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q8WVC0	intact:EBI-4291940	intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110618	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654	-	-	-	figure legend:supplemental 3a|comment:Recombinant hPAF1C complex has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606	intact-crc:9DBB9544B219C4C5|rigid:aLkqXA0Q9dgc2/PeDDxA7Xs+8mg	false	sufficient binding region:220..220-230..230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q8N7H5	intact:EBI-4291940	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110618	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N	-	-	-	figure legend:supplemental 3a|comment:Recombinant hPAF1C complex has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	intact-crc:9DBB9544B219C4C5|rigid:aLkqXA0Q9dgc2/PeDDxA7Xs+8mg	false	sufficient binding region:220..220-230..230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q8N7H5	intact:EBI-4291940	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110631	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N	-	-	-	figure legend:supplemental 3b|comment:A549 cells nuclear extract has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	intact-crc:606AE91E02E0E5E4|rigid:iWF1k17MiWYUN3soTiRrCjcGo7Q	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q6P1J9	intact:EBI-4291940	intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110631	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654	-	-	-	figure legend:supplemental 3b|comment:A549 cells nuclear extract has been used.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606	intact-crc:606AE91E02E0E5E4|rigid:iWF1k17MiWYUN3soTiRrCjcGo7Q	false	sufficient binding region:220-230	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O14646	uniprotkb:B2BUF1	intact:EBI-1560858|uniprotkb:Q17RZ3|ensembl:ENSP00000284049|ensembl:ENSP00000483667	intact:EBI-4291940	psi-mi:chd1_human(display_long)|uniprotkb:ATP-dependent helicase CHD1(gene name synonym)|uniprotkb:CHD1(gene name)|psi-mi:CHD1(display_short)	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marazzi et al. (2012)	pubmed:22419161	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001261.2|refseq:XP_005271924.1|dip:DIP-38922N|ensembl:ENSG00000153922(gene)|ensembl:ENST00000284049(transcript)|ensembl:ENST00000614616(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14646|rcsb pdb:2B2T|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2B2Y|rcsb pdb:2N39|rcsb pdb:4B4C|rcsb pdb:4NW2|rcsb pdb:4O42|rcsb pdb:5AFW|reactome:R-HSA-9018519	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	-	-	-	figure legend:1d|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/26	2014/10/16	rogid:KzH9c8MyoQh0Ph+KwSUktSa5qWM9606	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	intact-crc:CB6C273B599084AC|rigid:0R2CXeN/jHrTCxI8QuOw7BQW5RA	false	-	methylated lysine:229-229	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:B2BUF1	uniprotkb:Q8N7H5	intact:EBI-4291940	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemental 3c|curation depth:mimix curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	intact-crc:3E93B31E84B52877|rigid:14hHNgDa8z7h/fnNZQIzerhyzW8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:B2BUF1	uniprotkb:Q8N7H5	intact:EBI-4291940	intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35	psi-mi:b2buf1_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym)	psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Marazzi et al. (2012)	pubmed:22419161	taxid:480024("influenza a virus (a/wyoming/03/2003(h3n2))")|taxid:480024("Influenza A virus (A/Wyoming/03/2003(H3N2))")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038064|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR004208("Influenza B non-structural protein (NS1)")	refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N	go:"GO:0005634"(nucleus)	-	-	figure legend:supplemtal 3c|curation depth:mimix curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2012/04/26	2014/10/16	rogid:vMgydliMB3avTxSwsHQsOn8XdGU480024	rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606	intact-crc:3661C5D4CC1897A7|rigid:14hHNgDa8z7h/fnNZQIzerhyzW8	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P24928	uniprotkb:P03431	intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874	intact:EBI-2547514|uniprotkb:A4GXH1|uniprotkb:Q20N30|uniprotkb:Q8JUU7	psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym)	psi-mi:rdrp_i34a1(display_long)|uniprotkb:PB1(gene name)|psi-mi:PB1(display_short)|uniprotkb:Polymerase basic protein 1(gene name synonym)|uniprotkb:RNA-directed RNA polymerase subunit P1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Marazzi et al. (2012)	pubmed:22419161	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110672	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095	go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019083"(viral transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0031904"(endosome lumen)|go:"GO:0039523"(suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity)|go:"GO:0039694"(viral RNA genome replication)|interpro:IPR001407(RNA-dependent RNA polymerase, PB1 subunit, Influenza-ype)|interpro:IPR007099(RNA-directed RNA polymerase, negative-strand RNA virus)|rcsb pdb:2ZNL|rcsb pdb:2ZTT|rcsb pdb:3A1G|go:"GO:0042025"(host cell nucleus)|refseq:NP_040985.1|reactome:R-HSA-168255|reactome:R-HSA-168271|reactome:R-HSA-168275|reactome:R-HSA-168288|reactome:R-HSA-168298|reactome:R-HSA-168302|reactome:R-HSA-168303|reactome:R-HSA-168325|reactome:R-HSA-168330|reactome:R-HSA-168333|dip:DIP-56974N|reactome:R-HSA-168336|reactome:R-HSA-192814|reactome:R-HSA-192823|reactome:R-HSA-192869|reactome:R-HSA-192905	-	-	-	figure legend:supplemental 7|curation depth:mimix curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2012/04/26	2014/10/16	rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606	rogid:57q1RvwNj9GxHcwpri3Kb7yBFm8211044	intact-crc:65021DA9EF51821D|rigid:yuFOm8ftf2K0ugpPrO1fzxzFhIs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P24928	uniprotkb:P03466	intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874	intact:EBI-2547640|uniprotkb:Q20N34|uniprotkb:Q58NB3|uniprotkb:Q67228|uniprotkb:Q80AB4	psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym)	psi-mi:ncap_i34a1(display_long)|uniprotkb:NP(gene name)|psi-mi:NP(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Marazzi et al. (2012)	pubmed:22419161	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6110672	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095	go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0031904"(endosome lumen)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR002141("Influenza virus nucleoprotein (NP)")|rcsb pdb:2BST|rcsb pdb:2WFS|rcsb pdb:4NQV|rcsb pdb:4ZDU|rcsb pdb:5NPZ|rcsb pdb:5NQ3|rcsb pdb:5V5O|reactome:R-HSA-168255|reactome:R-HSA-168271|reactome:R-HSA-168275|reactome:R-HSA-168288|reactome:R-HSA-168298|reactome:R-HSA-168302|reactome:R-HSA-168303|reactome:R-HSA-168316|reactome:R-HSA-168325|reactome:R-HSA-168330|reactome:R-HSA-168333|reactome:R-HSA-168336|reactome:R-HSA-192814|reactome:R-HSA-192823|reactome:R-HSA-192869|reactome:R-HSA-192905|refseq:NP_040982.1|dip:DIP-43998N|mint:P03466	-	-	-	figure legend:supplemental 7|curation depth:mimix curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2012/04/26	2014/10/16	rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606	rogid:N04UBXG2kQhoSQNftH7+NFsPJPU211044	intact-crc:65021DA9EF51821D|rigid:yuFOm8ftf2K0ugpPrO1fzxzFhIs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)